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Biomedical Research in Urology

The Biomedical Research in Urology group is interested in the study of hormone-dependent cancers, in particular prostate cancer (but not limited to it).

Our efforts are focused on finding, on the one hand, tools that help us in the early diagnosis of the disease, in the best differentiation of tumors according to their aggressiveness and their response to therapy, and finally in finding effective therapies against it.

From a molecular point of view, we focus our studies mainly on cell signaling processes related to the cell cycle and mitosis (with kinesins, kinases and ubiquitin ligases as main targets).

Our multidisciplinary group is made up of molecular biologists and urologists, and we collaborate with oncologists, pathologists and specialists in other diseases when required.

We work with in silico data obtained with different "omics" techniques, samples and clinical data from patients, in vitro and in vivo models, to answer the questions raised.

Publications

Is Tumor Budding a New Predictor for Early Cystectomy in pT1 High-Grade Bladder Cancer?

PMID: 34352790
Journal: UROLOGIA INTERNATIONALIS
Year: 2022
Reference: Urol Int. 2022;106(2):154-162. doi: 10.1159/000517543. Epub 2021 Aug 5.
Impact factor:
Publication type: Paper in international publication
Authors: Aula Olivar, Ana; Carrion Puig, Albert; De Torres Ramirez, Ines M; Lozano Palacio, Fernando; Raventos Busquets, Carles X; Semidey, M Eugenia; Trilla Herrera, Enrique et al.
DOI: 10.1159/000517543

The importance of appropriate castrate level measurements of serum testosterone in prostate cancer patients.

PMID: 35101469
Journal: RADIOTHERAPY AND ONCOLOGY
Year: 2022
Reference: Radiother Oncol. 2022 Jan 28. pii: S0167-8140(22)00032-9. doi: 10.1016/j.radonc.2022.01.028.
Impact factor:
Publication type: Letter or abstract
Authors: Morote, Juan et al.
DOI: 10.1016/j.radonc.2022.01.028

Perioperative and Functional Outcomes of Robot-assisted Ureteroenteric Reimplantation: A Multicenter Study of Seven Referral Institutions.

PMID: 35024631
Journal: European Urology Open Science
Year: 2022
Reference: Eur Urol Open Sci. 2022 Jan 3;35:47-53. doi: 10.1016/j.euros.2021.11.005. eCollection 2022 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Abaza, Ronney; Bonet, Xavier; Breda, Alberto; Carrion, Albert; Eun, Daniel; Gaya, Josep Maria; Guru, Khurshid A; Hosseini, Abolfazl; Hussein, Ahmed Aly; Iqbal, Umar et al.
DOI: 10.1016/j.euros.2021.11.005

Re: Magdalena Gortz, Jan Philipp Radtke, Gencay Hatiboglu, et al. The Value of Prostate-specific Antigen Density for Prostate Imaging-Reporting and Data System 3 Lesions on Multiparametric Magnetic Resonance Imaging: A Strategy to Avoid Unnecessary Prostate Biopsies. Eur Urol Focus 2021;7:325-31.

PMID: 34992001
Journal: European Urology Focus
Year: 2022
Reference: Eur Urol Focus. 2022 Sep;8(5):1557-1558. doi: 10.1016/j.euf.2021.12.007. Epub 2022 Jan 3.
Impact factor:
Publication type: Letter or abstract
Authors: Morote, Juan; Planas, Jacques; Trilla, Enrique et al.
DOI: 10.1016/j.euf.2021.12.007

Blog

News

On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.

The work led by Dr. Regis demonstrates that performing robotic reconstruction after radical prostatectomy is associated with better urinary control.

A clinical trial with the prototype of the device shows that the use of this technology improves patient monitoring by nurses and reduces post-surgical complications.