About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Biomedical Research in Urology group is interested in the study of hormone-dependent cancers, in particular prostate cancer (but not limited to it).
Our efforts are focused on finding, on the one hand, tools that help us in the early diagnosis of the disease, in the best differentiation of tumors according to their aggressiveness and their response to therapy, and finally in finding effective therapies against it.
From a molecular point of view, we focus our studies mainly on cell signaling processes related to the cell cycle and mitosis (with kinesins, kinases and ubiquitin ligases as main targets).
Our multidisciplinary group is made up of molecular biologists and urologists, and we collaborate with oncologists, pathologists and specialists in other diseases when required.
We work with in silico data obtained with different "omics" techniques, samples and clinical data from patients, in vitro and in vivo models, to answer the questions raised.
PMID: 35021312 Journal: World Journal of Mens Health Year: 2022 Reference: World J Mens Health. 2022 Apr;40(2):270-279. doi: 10.5534/wjmh.210117. Epub 2021 Dec 27. Impact factor: Publication type: Paper in international publication Authors: Campistol, Miriam; Celma, Anna; de Torres, Ines; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Roche, Sarai; Santamaria, Anna; Semidey, Maria E et al. DOI: 10.5534/wjmh.210117
PMID: 35327491 Journal: Biomedicines Year: 2022 Reference: Biomedicines. 2022 Mar 17;10(3). pii: biomedicines10030689. doi: 10.3390/biomedicines10030689. Impact factor: Publication type: Review in international publication Authors: Aguilar, Adriana; Morote, Juan; Planas, Jacques; Trilla, Enrique et al. DOI: 10.3390/biomedicines10030689
PMID: 35326740 Journal: Cancers Year: 2022 Reference: Cancers (Basel). 2022 Mar 21;14(6). pii: cancers14061589. doi: 10.3390/cancers14061589. Impact factor: Publication type: Paper in international publication Authors: Abascal, Jose M; Borque-Fernando, Angel; Celma, Anna; de Torres, Ines M; Escobar, Manel; Esteban, Luis M; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas et al. DOI: 10.3390/cancers14061589
PMID: 35332883 Journal: ARCHIVOS ESPANOLES DE UROLOGIA Year: 2022 Reference: Arch Esp Urol. 2022 Mar;75(2):133-143. Impact factor: Publication type: Paper in national publication Authors: Carrion, Albert; Lozano, Fernando; Raventos, Carles Xavier; Trilla, Enrique et al. DOI:
PMID: 32067845 Journal: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS Year: 2020 Reference: Urol Oncol. 2020 May;38(5):410-417. doi: 10.1016/j.urolonc.2019.12.013. Epub 2020 Feb 15. Impact factor: Publication type: Paper in international publication Authors: Celma, Anna; de Torres, Ines M; Diaz, Fernando; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Roche, Sarai; Semedey, Maria E; Trilla, Enrique et al. DOI: 10.1016/j.urolonc.2019.12.013
PMID: 33194736 Journal: Frontiers in Oncology Year: 2020 Reference: Front Oncol. 2020 Oct 22;10:586069. doi: 10.3389/fonc.2020.586069. eCollection 2020. Impact factor: 4.848 Publication type: Review in international publication Authors: Kondoh, Hiroshi, Alvarez-Meythaler, Jose G, Garcia-Mayea, Yoelsis, Mir, Cristina, LLeonart, Matilde E et al. DOI: 10.3389/fonc.2020.586069
PMID: 32647375 Journal: Communications Biology Year: 2020 Reference: Commun Biol. 2020 Jul 9;3(1):366. doi: 10.1038/s42003-020-1092-0. Impact factor: 4.165 Publication type: Paper in international publication Authors: Granado-Martinez, Paula, Garcia-Ortega, Sara, Gonzalez-Sanchez, Elena, McGrail, Kimberley, Selgas, Rafael, Grueso, Judit, Gil, Rosa, Naldaiz-Gastesi, Neia, Rhodes, Ana C, Hernandez-Losa, Javier et al. DOI: 10.1038/s42003-020-1092-0
PMID: 30770954 Journal: CELLULAR AND MOLECULAR LIFE SCIENCES Year: 2019 Reference: Cell Mol Life Sci. 2019 Jun;76(11):2231-2243. doi: 10.1007/s00018-019-03041-4. Epub 2019 Feb 15. Impact factor: Publication type: Paper in international publication Authors: Boloix, Ariadna; de Toledo, Josep Sanchez; Gallego, Soledad; Henrich, Kai-Oliver; Jimenez, Carlos; Masanas, Marc; Masia, Nuria; Paris-Coderch, Laia; Piskareva, Olga; Roma, Josep et al. DOI: 10.1007/s00018-019-03041-4
PMID: 30700322 Journal: BMC research notes Year: 2019 Reference: BMC Res Notes. 2019 Jan 30;12(1):68. doi: 10.1186/s13104-019-4100-z. Impact factor: Publication type: Paper in international publication Authors: Agullo-Ortuno, M Teresa; Alcaraz, Antonio; Asensi-Puig, Adria; de Torres, Ines; Donovan, Michael J; Erill, Nadina; Gonzalez-Garcia, Judit; Gonzalez-Rumayor, Victor; Lopez-Martin, Jose A; Mengual, Lourdes et al. DOI: 10.1186/s13104-019-4100-z
PMID: 30667539 Journal: HISTOPATHOLOGY Year: 2019 Reference: Histopathology. 2019 Jul;75(1):4-19. doi: 10.1111/his.13828. Epub 2019 May 14. Impact factor: Publication type: Editorail in international publication Authors: Castellvi, J; De Torres, I; Hernandez-Losa, J; Hummer, S; Martinez-Saez, E; Matias Guiu, X; Peg, V; Ramon Y Cajal, S et al. DOI: 10.1111/his.13828
PMID: 30628520 Journal: Scandinavian Journal of Urology Year: 2019 Reference: Scand J Urol. 2019 Feb;53(1):21-25. doi: 10.1080/21681805.2018.1551243. Epub 2019 Jan 10. Impact factor: Publication type: Paper in international publication Authors: Celma, Ana; Lopez, Ricardo; Lorente, David; Morote, Juan; Placer, Jose; Planas, Jacques; Regis, Lucas; Roche, Sarai; Trilla, Enrique et al. DOI: 10.1080/21681805.2018.1551243
PMID: 23606355 Journal: Clinical & Translational Oncology Year: 2014 Reference: Clin Transl Oncol. 2014 Jan;16(1):102-6. doi: 10.1007/s12094-013-1045-x. Epub 2013 Apr 20. Impact factor: Publication type: Paper in international publication Authors: Carles, J; Maldonado, X; Morales-Barrera, R; Morote, J; Nunez, I; Suarez, C; Valverde, C et al. DOI: 10.1007/s12094-013-1045-x
PMID: 24390735 Journal: CANCER RESEARCH Year: 2014 Reference: Cancer Res. 2014 Mar 1;74(5):1416-28. doi: 10.1158/0008-5472.CAN-13-1671. Epub 2014 Jan 3. Impact factor: Publication type: Paper in international publication Authors: Cuadros, Thais; de Torres, Ines; Itarte, Emilio; Lopez-Hellin, Joan; Meseguer, Anna; Morote, Juan; Ramon Y Cajal, Santiago; Salcedo, Mayte; Sanchez, Alex; Sarro, Eduard et al. DOI: 10.1158/0008-5472.CAN-13-1671
PMID: 23268930 Journal: MOLECULAR & CELLULAR PROTEOMICS Year: 2013 Reference: Mol Cell Proteomics. 2013 May;12(5):1046-60. doi: 10.1074/mcp.M112.021618. Epub 2012 Dec 26. Impact factor: Publication type: Paper in international publication Authors: Baselga, Jose; Gregori, Josep; Mendez, Olga; Salvans, Candida; Villanueva, Josep; Villarreal, Laura et al. DOI: 10.1074/mcp.M112.021618
On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.
The work led by Dr. Regis demonstrates that performing robotic reconstruction after radical prostatectomy is associated with better urinary control.
A clinical trial with the prototype of the device shows that the use of this technology improves patient monitoring by nurses and reduces post-surgical complications.
