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Cardiovascular Diseases

Cardiovascular Diseases group is a translational research group within the Cardiology Department of Vall d’Hebron Hospital that performs laboratory, clinical and epidemiological research. In the CIBERCV network we are within the topic of descriptor 2 “Arterial disease, thrombosis and myocardial ischemia-reperfusion injury”. Our contributions in these topics address the following lines: 

  • Myocardial ischemia-reperfusion injury (i.e. mechanisms of endogenous cardioprotection, ischemic conditioning and remodeling), 
  • Coronary artery disease (i.e. genetic factors involved in coronary artery disease, determinants of thrombotic complications and prognosis), 
  • Aortic diseases (i.e. determinants of aorta dilatation, aortic biomechanics abnormalities in Marfan´s syndrome, and new imaging methods), 
  • Congenital/familiar heart diseases (i.e. genetic determinants and prognosis factors). 

In the CIBERESP network, our group is interested in the study of effectiveness/cost-effectiveness of cardiovascular interventions, health outcome research and methods in clinical research. The group has 19 principal investigators, 32 active projects and clinical trial and has been done 142 publications in 2020.

Publications

Relationship Between Maximal Left Ventricular Wall Thickness and Sudden Cardiac Death in Childhood Onset Hypertrophic Cardiomyopathy.

PMID: 35491873
Journal: Circulation. Arrhythmia and Electrophysiology
Year: 2022
Reference: Circ Arrhythm Electrophysiol. 2022 May;15(5):e010075. doi: 10.1161/CIRCEP.121.010075. Epub 2022 May 2.
Impact factor: 6.572
Publication type: Paper in international publication
Authors: Cervi, Elena, Ziolkowska, Lidia, Olivotto, Iacopo, Khraiche, Diala, Limongelli, Giuseppe, Anastasakis, Aris, Weintraub, Robert, Biagini, Elena, Ragni, Luca, Prendiville, Terrence et al.
DOI: 10.1161/CIRCEP.121.010075

Combination of late gadolinium enhancement and genotype improves prediction of prognosis in non-ischemic dilated cardiomyopathy.

PMID: 35485241
Journal: EUROPEAN JOURNAL OF HEART FAILURE
Year: 2022
Reference: Eur J Heart Fail. 2022 Apr 29. doi: 10.1002/ejhf.2514.
Impact factor: 15.534
Publication type: Paper in international publication
Authors: Barriales-Villa, Roberto, Mogollon-Jimenez, Maria Victoria, Garcia-Pinilla, Jose M, Garcia-Granja, Pablo Elpidio, Climent, Vicente, Palomino-Doza, Julian, Garcia-Alvarez, Ana, Alvarez-Barredo, Maria, Borrego, Eva Cabrera, Ripoll-Vera, Tomas et al.
DOI: 10.1002/ejhf.2514

Is humoral and cellular response to SARS-CoV-2 vaccine modified by DMT in patients with multiple sclerosis and other autoimmune diseases?

PMID: 35475363
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jun;28(7):1138-1145. doi: 10.1177/13524585221089540. Epub 2022 Apr 27.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Arrambide, Georgina, Otero-Romero, Susana, Pappolla, Agustin, Tagliani, Paula, Lopez-Maza, Samuel, Cardenas-Robledo, Simon, Esperalba, Juliana, Fernandez-Naval, Candela, Martinez-Gallo, Monica, Castillo, Mireia et al.
DOI: 10.1177/13524585221089540

Can an ultrathin strut stent design and a polymer free, proendothelializing probucol matrix coating improve early strut healing? The FRIENDLY-OCT trial. An intra-patient randomized study with OCT, evaluating early strut coverage of a novel probucol coated polymer-free and ultra-thin strut sirolimus-eluting stent compared to a biodegradable polymer sirolimus-eluting stent.

PMID: 35472561
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2022
Reference: Int J Cardiol. 2022 Aug 1;360:13-20. doi: 10.1016/j.ijcard.2022.04.043. Epub 2022 Apr 25.
Impact factor: 4.164
Publication type: Paper in international publication
Authors: Irurueta, Imanol Otaegui, Sucarrats, Silvia Gonzalez, Molina, Jose Luis Barron, de Prado, Armando Perez, Massotti, Monica, Ramirez, Maria Angeles Carmona, Marti, Gerard, Bellera, Neus, Serra, Bernat, Domingo, Enric et al.
DOI: 10.1016/j.ijcard.2022.04.043

Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes.

PMID: 34304861
Journal: ANNALS OF THORACIC SURGERY
Year: 2021
Reference: Ann Thorac Surg. 2021 Sep;112(3):1005-1022. doi: 10.1016/j.athoracsur.2021.05.001. Epub 2021 Jul 22.
Impact factor: 4.33
Publication type: Paper in international publication
Authors: Fedak, Paul W M, Girdauskas, Evaldas, Delgado, Victoria, Abbara, Suhny, Lansac, Emmanuel, Prakash, Siddharth K, Bissell, Malenka M, Popescu, Bogdan A, Hope, Michael D, Sitges, Marta et al.
DOI: 10.1016/j.athoracsur.2021.05.001

International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes.

PMID: 34304860
Journal: ANNALS OF THORACIC SURGERY
Year: 2021
Reference: Ann Thorac Surg. 2021 Sep;112(3):e203-e235. doi: 10.1016/j.athoracsur.2020.08.119. Epub 2021 Jul 22.
Impact factor: 4.33
Publication type: Paper in international publication
Authors: Markl, Michael, Fedak, Paul W M, Girdauskas, Evaldas, Delgado, Victoria, Abbara, Suhny, Lansac, Emmanuel, Prakash, Siddharth K, Bissell, Malenka M, Popescu, Bogdan A, Hope, Michael D et al.
DOI: 10.1016/j.athoracsur.2020.08.119

International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.

PMID: 34304896
Journal: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
Year: 2021
Reference: J Thorac Cardiovasc Surg. 2021 Sep;162(3):e383-e414. doi: 10.1016/j.jtcvs.2021.06.019. Epub 2021 Jul 22.
Impact factor: 5.209
Publication type: Paper in international publication
Authors: Delgado, Victoria, Abbara, Suhny, Lansac, Emmanuel, Prakash, Siddharth K, Bissell, Malenka M, Popescu, Bogdan A, Hope, Michael D, Sitges, Marta, Thourani, Vinod H, Pibarot, Phillippe et al.
DOI: 10.1016/j.jtcvs.2021.06.019

Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional, and research purposes.

PMID: 34304894
Journal: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
Year: 2021
Reference: J Thorac Cardiovasc Surg. 2021 Sep;162(3):781-797. doi: 10.1016/j.jtcvs.2021.05.008. Epub 2021 Jul 22.
Impact factor: 5.209
Publication type: Paper in international publication
Authors: Roberts, William C, Delgado, Victoria, Abbara, Suhny, Lansac, Emmanuel, Prakash, Siddharth K, Bissell, Malenka M, Popescu, Bogdan A, Hope, Michael D, Sitges, Marta, Thourani, Vinod H et al.
DOI: 10.1016/j.jtcvs.2021.05.008

Age-specific reference values for carotid arterial stiffness estimated by ultrasonic wall tracking.

PMID: 31435004
Journal: JOURNAL OF HUMAN HYPERTENSION
Year: 2020
Reference: J Hum Hypertens. 2020 Mar;34(3):214-222. doi: 10.1038/s41371-019-0228-5. Epub 2019 Aug 21.
Impact factor: 2.26
Publication type: Paper in international publication
Authors: Evangelista, Arturo, Lancellotti, Patrizio, Leftheriotis, Georges, Kozakova, Michaela, Palombo, Carlo, Fraser, Alan G, Popescu, Bogdan A, Zamorano, Jose L, Vinereanu, Dragos, Vriz, Olga et al.
DOI: 10.1038/s41371-019-0228-5

Parvovirus B19 Myocarditis: Looking Beyond the Heart.

PMID: 31335286
Journal: PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
Year: 2020
Reference: Pediatr Dev Pathol. 2020 Mar-Apr;23(2):158-162. doi: 10.1177/1093526619865641. Epub 2019 Jul 23.
Impact factor: 0.885
Publication type: Paper in international publication
Authors: Izquierdo-Blasco, Jaume, Salcedo Allende, Maria Teresa, Codina Grau, Maria Gemma, Gran, Ferran, Martinez Saez, Elena, Balcells, Joan et al.
DOI: 10.1177/1093526619865641

Late Cerebrovascular Events Following Transcatheter Aortic Valve Replacement.

PMID: 32171718
Journal: JACC-Cardiovascular Interventions
Year: 2020
Reference: JACC Cardiovasc Interv. 2020 Apr 13;13(7):872-881. doi: 10.1016/j.jcin.2019.11.022. Epub 2020 Mar 11.
Impact factor: 8.432
Publication type: Paper in international publication
Authors: Rodes-Cabau, Josep, Kalavrouziotis, Dimitri, Couture, Thomas, Fischer, Quentin, Muntane-Carol, Guillem, Urena, Marina, Munoz-Garcia, Antonio, Gutierrez, Enrique, Regueiro, Ander, Serra, Vicenc et al.
DOI: 10.1016/j.jcin.2019.11.022

Cyclophilins A and B Oppositely Regulate Renal Tubular Epithelial Cell Phenotype.

PMID: 32162654
Journal: Journal of Molecular Cell Biology
Year: 2020
Reference: J Mol Cell Biol. 2020 Jul 1;12(7):499-514. doi: 10.1093/jmcb/mjaa005.
Impact factor: 4
Publication type: Paper in international publication
Authors: Gundelach, Justin H, Sarro, Eduard, Duran, Monica, Rico, Ana, Bou-Teen, Diana, Fernandez-Majada, Vanesa, Croatt, Anthony J, Nath, Karl A, Salcedo, Maria Teresa, Meseguer, Anna et al.
DOI: 10.1093/jmcb/mjaa005

Comments on the 2018 ESC/ESH Guidelines for the Management of Arterial Hypertension.

PMID: 30704721
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Feb;72(2):104-108. doi: 10.1016/j.rec.2018.12.001.
Impact factor: 5.078
Publication type: Editorial in national publication
Authors: Mazon, Pilar, Marin, Francisco, Cosin-Sales, Juan, Cordero, Alberto, Roldan, Inmaculada, Garcia-Moll, Xavier, Vazquez, Rafael, Coca, Antonio, Escobar, Carlos, Barrios, Vivencio et al.
DOI: 10.1016/j.rec.2018.12.001

Invasive Versus Conservative Strategy in Frail Patients With NSTEMI: The MOSCA-FRAIL Clinical Trial Study Design.

PMID: 29525724
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Feb;72(2):154-159. doi: 10.1016/j.rec.2018.02.007. Epub 2018 Mar 7.
Impact factor: 5.078
Publication type: Paper in international publication
Authors: Sanchis, Juan, Ariza-Sole, Albert, Abu-Assi, Emad, Alegre, Oriol, Alfonso, Fernando, Barrabes, Jose Antonio, Baz, Jose Antonio, Carol, Antonio, Diez Villanueva, Pablo, Garcia Del Blanco, Bruno et al.
DOI: 10.1016/j.recesp.2018.01.028

Colchicine Administered in the First Episode of Acute Idiopathic Pericarditis: A Randomized Multicenter Open-label Study.

PMID: 30683494
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Sep;72(9):709-716. doi: 10.1016/j.rec.2018.11.016. Epub 2019 Jan 22.
Impact factor: 5.078
Publication type: Paper in national publication
Authors: Sambola, Antonia, Roca Luque, Ivo, Merce, Jordi, Alguersuari, Joan, Francisco-Pascual, Jaume, Garcia-Dorado, David, Sagrista-Sauleda, Jaume et al.
DOI: 10.1016/j.rec.2018.11.016

Comments on the 2018 ESC/EACTS Guidelines for Myocardial Revascularization.

PMID: 30580785
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Jan;72(1):16-20. doi: 10.1016/j.rec.2018.11.010.
Impact factor: 5.078
Publication type: Review in national publication
Authors: Bueno, Hector, Ibanez, Borja, Bautista-Hernandez, Victor, Alfonso, Fernando, Berga Congost, Gemma, Carnero, Manuel, Viana-Tejedor, Ana, Cid-Alvarez, Belen A, de la Torre Hernandez, Jose Maria, Franco-Pelaez, Juan Antonio et al.
DOI: 10.1016/j.rec.2018.11.010

Recurrent purulent pericarditis secondary to a giant bronchogenic cyst.

PMID: 29029080
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2018
Reference: Eur Heart J Cardiovasc Imaging. 2018 Jan 1;19(1):118. doi: 10.1093/ehjci/jex208.
Impact factor: 8.336
Publication type: Paper in international publication
Authors: Valente, Filipa, Migliori, Maximo, Segura, Cristobal, Rodriguez Palomares, Jose et al.
DOI: 10.1093/ehjci/jex208

Short-term exposure to air pollutants increases the risk of ST elevation myocardial infarction and of infarct-related ventricular arrhythmias and mortality.

PMID: 29056239
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2018
Reference: Int J Cardiol. 2018 Jan 1;250:35-42. doi: 10.1016/j.ijcard.2017.10.004. Epub 2017 Oct 5.
Impact factor: 4.034
Publication type: Paper in international publication
Authors: Baneras, Jordi, Ferreira-Gonzalez, Ignacio, Marsal, Josep Ramon, Barrabes, Jose A, Ribera, Aida, Lidon, Rosa Maria, Domingo, Enric, Marti, Gerard, Garcia-Dorado, David et al.
DOI: 10.1016/j.ijcard.2017.10.004

Mitochondrial Cx43, an important component of cardiac preconditioning.

PMID: 28642043
Journal: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Year: 2018
Reference: Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):174-181. doi: 10.1016/j.bbamem.2017.06.011. Epub 2017 Jun 20.
Impact factor: 3.438
Publication type: Review in international publication
Authors: Rodriguez-Sinovas, Antonio, Ruiz-Meana, Marisol, Denuc, Amanda, Garcia-Dorado, David et al.
DOI: 10.1016/j.bbamem.2017.06.011

Blog

News

The consensus document is the result of multidisciplinary work that takes into account the risks associated with all stages of women's lives and the differences compared to men.

The study, which involved Vall d'Hebron, developed an action plan to efficiently allocate resources to patients most at risk of suffering this complication.

In light of this evidence, hospitals such as Vall d'Hebron have already started to include warnings about environmental pollution in their hospital discharge plans after a myocardial infarction.