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Cardiovascular Diseases

Cardiovascular Diseases group is a translational research group within the Cardiology Department of Vall d’Hebron Hospital that performs laboratory, clinical and epidemiological research. In the CIBERCV network we are within the topic of descriptor 2 “Arterial disease, thrombosis and myocardial ischemia-reperfusion injury”. Our contributions in these topics address the following lines: 

  • Myocardial ischemia-reperfusion injury (i.e. mechanisms of endogenous cardioprotection, ischemic conditioning and remodeling), 
  • Coronary artery disease (i.e. genetic factors involved in coronary artery disease, determinants of thrombotic complications and prognosis), 
  • Aortic diseases (i.e. determinants of aorta dilatation, aortic biomechanics abnormalities in Marfan´s syndrome, and new imaging methods), 
  • Congenital/familiar heart diseases (i.e. genetic determinants and prognosis factors). 

In the CIBERESP network, our group is interested in the study of effectiveness/cost-effectiveness of cardiovascular interventions, health outcome research and methods in clinical research. The group has 19 principal investigators, 32 active projects and clinical trial and has been done 142 publications in 2020.

Publications

Transcatheter versus surgical aortic valve replacement in patients with morbid obesity: a multicentre propensity score-matched analysis.

PMID: 35321860
Journal: EuroIntervention
Year: 2022
Reference: EuroIntervention. 2022 Mar 24. pii: EIJ-D-21-00891. doi: 10.4244/EIJ-D-21-00891.
Impact factor: 6.534
Publication type: Paper in international publication
Authors: Cobiella, Javier, Toggweiler, Stefan, Saia, Francesco, Dabrowski, Maciej, Serra, Vicent, Alfonso, Fernando, Ribeiro, Henrique B, Regueiro, Ander, Alpieri, Alberto, Gil Ongay, Aritz et al.
DOI: 10.4244/EIJ-D-21-00891

Sex-Related Differences in Patients With Unexplained Syncope and Bundle Branch Block: Lower Risk of AV Block and Lesser Need for Cardiac Pacing in Women.

PMID: 35282384
Journal: Frontiers in Cardiovascular Medicine
Year: 2022
Reference: Front Cardiovasc Med. 2022 Feb 25;9:838473. doi: 10.3389/fcvm.2022.838473. eCollection 2022.
Impact factor: 6.05
Publication type: Paper in international publication
Authors: Francisco-Pascual, Jaume, Rivas-Gandara, Nuria, Bach-Oller, Montserrat, Badia-Molins, Clara, Maymi-Ballesteros, Manel, Benito, Begona, Perez-Rodon, Jordi, Santos-Ortega, Alba, Sambola-Ayala, Antonia, Roca-Luque, Ivo et al.
DOI: 10.3389/fcvm.2022.838473

Proteins and pathways in atrial fibrillation and atrial cardiomyopathy underlying cryptogenic stroke.

PMID: 35281755
Journal: International journal of cardiology. Heart & vasculature
Year: 2022
Reference: Int J Cardiol Heart Vasc. 2022 Mar 7;39:100977. doi: 10.1016/j.ijcha.2022.100977. eCollection 2022 Apr.
Impact factor: 0
Publication type: Paper in international publication
Authors: Pala, Elena, Pagola, Jorge, Juega, Jesus, Francisco-Pascual, Jaume, Penalba, Anna, Rodriguez, Maite, De Lera Alfonso, Mercedes, Arenillas, Juan F, Cabezas, Juan Antonio, Moniche, Francisco et al.
DOI: 10.1016/j.ijcha.2022.100977

Prognostic implications of left atrial dilation in aortic regurgitation due to bicuspid aortic valve.

PMID: 33833069
Journal: HEART
Year: 2022
Reference: Heart. 2022 Jan;108(2):137-144. doi: 10.1136/heartjnl-2020-318907. Epub 2021 Apr 8.
Impact factor: 5.994
Publication type: Paper in international publication
Authors: Shanks, Miriam, Popescu, Bogdan A, Galian-Gay, Laura, Fijalkowski, Marcin, Liang, Michael, Tay, Edgar, Ajmone Marsan, Nina, Selvanayagam, Joseph B, Yeo, Tiong-Cheng, Pinto, Fausto J et al.
DOI: 10.1136/heartjnl-2020-318907

Worldwide Diagnostic Reference Levels for Single-Photon Emission Computed Tomography Myocardial Perfusion Imaging: Findings From INCAPS.

PMID: 32828783
Journal: JACC-Cardiovascular Imaging
Year: 2021
Reference: JACC Cardiovasc Imaging. 2021 Mar;14(3):657-665. doi: 10.1016/j.jcmg.2020.06.029. Epub 2020 Aug 19.
Impact factor: 14.805
Publication type: Paper in international publication
Authors: Hirschfeld, Cole B, Dondi, Maurizio, Pascual, Thomas N B, Mercuri, Mathew, Vitola, Joao, Kashyap, R, Lele, V, Magboo, V P C, Mahmarian, J J, Meeks, J B et al.
DOI: 10.1016/j.jcmg.2020.06.029

Imaging and Biomarkers in Acute Aortic Syndromes: Diagnostic and Prognostic Implications.

PMID: 32958324
Journal: CURRENT PROBLEMS IN CARDIOLOGY
Year: 2021
Reference: Curr Probl Cardiol. 2021 Mar;46(3):100654. doi: 10.1016/j.cpcardiol.2020.100654. Epub 2020 Jul 22.
Impact factor: 5.2
Publication type: Review in international publication
Authors: Bossone, Eduardo, Czerny, Martin, Lerakis, Stamatios, Rodriguez-Palomares, Jose, Kukar, Nina, Ranieri, Brigida, Russo, Valentina, Punzo, Bruna, Cocchia, Rosangela, Cademartiri, Filippo et al.
DOI: 10.1016/j.cpcardiol.2020.100654

Prevalence and Clinical Outcomes of Dystrophin associated Dilated Cardiomyopathy without severe skeletal myopathy.

PMID: 34050592
Journal: EUROPEAN JOURNAL OF HEART FAILURE
Year: 2021
Reference: Eur J Heart Fail. 2021 Aug;23(8):1276-1286. doi: 10.1002/ejhf.2250. Epub 2021 Jun 9.
Impact factor: 15.534
Publication type: Paper in international publication
Authors: Paniagua-Martin, Maria Jesus, Stojkovic, Tanya, Shomanova, Zornitsa, Bermudez-Jimenez, Francisco, Palladino, Alberto, Freimark, Dov, Garcia-Alvarez, Maria I, Jorda, Paloma, Dominguez, Fernando, Ochoa, Juan Pablo et al.
DOI: 10.1002/ejhf.2250

Usefulness of skin advanced glycation end products to predict coronary artery calcium score in patients with type 2 diabetes.

PMID: 34032928
Journal: ACTA DIABETOLOGICA
Year: 2021
Reference: Acta Diabetol. 2021 Oct;58(10):1403-1412. doi: 10.1007/s00592-021-01735-5. Epub 2021 May 25.
Impact factor: 4.28
Publication type: Paper in international publication
Authors: Planas, Alejandra, Simo-Servat, Olga, Baneras, Jordi, Sanchez, Monica, Garcia, Esther, Ortiz, Angel M, Ruiz-Meana, Marisol, Hernandez, Cristina, Ferreira-Gonzalez, Ignacio, Simo, Rafael et al.
DOI: 10.1007/s00592-021-01735-5

Correction: Age-specific reference values for carotid arterial stiffness estimated by ultrasonic wall tracking.

PMID: 32001827
Journal: JOURNAL OF HUMAN HYPERTENSION
Year: 2020
Reference: J Hum Hypertens. 2020 Mar;34(3):258. doi: 10.1038/s41371-020-0304-x.
Impact factor: 2.26
Publication type: Letter or abstract
Authors: Uejima, Tokuhisa, Dunstan, Frank D, Arbustini, Eloisa, Loboz-Grudzien, Krystyna, Hughes, Alun D, Carerj, Scipione, Favalli, Valentina, Antonini-Canterin, Francesco, Vriz, Olga, Vinereanu, Dragos et al.
DOI: 10.1038/s41371-020-0304-x

Determinants of long-term outcome of repaired pulmonary valve stenosis.

PMID: 31130344
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2020
Reference: Rev Esp Cardiol (Engl Ed). 2020 Feb;73(2):131-138. doi: 10.1016/j.rec.2019.02.014. Epub 2019 May 24.
Impact factor: 4.642
Publication type: Paper in national publication
Authors: Galian-Gay, Laura, Gordon, Blanca, Marsal, Josep Ramon, Rafecas, Agnes, Pijuan Domenech, Antonia, Castro, Miguel Angel, Sureda, Carlos, Miranda, Berta, Marti, Gerard, Garcia-Dorado, David et al.
DOI: 10.1016/j.recesp.2019.02.020

Acute Coronary Syndrome Following Transcatheter Aortic Valve Replacement.

PMID: 31992059
Journal: Circulation-Cardiovascular Interventions
Year: 2020
Reference: Circ Cardiovasc Interv. 2020 Feb;13(2):e008620. doi: 10.1161/CIRCINTERVENTIONS.119.008620. Epub 2020 Jan 29.
Impact factor: 5.493
Publication type: Paper in international publication
Authors: Serra, Vicenc, Alperi, Alberto, Nombela-Franco, Luis, Fischer, Quentin, Veiga, Gabriela, Donaint, Pierre, Asmarats, Lluis, Vilalta, Victoria, Chamandi, Chekrallah, Regueiro, Ander et al.
DOI: 10.1161/CIRCINTERVENTIONS.119.008620

A single nucleotide deletion resulting in a frameshift in exon 4 of TAB2 is associated with a polyvalular syndrome.

PMID: 31981616
Journal: European Journal of Medical Genetics
Year: 2020
Reference: Eur J Med Genet. 2020 Apr;63(4):103854. doi: 10.1016/j.ejmg.2020.103854. Epub 2020 Jan 23.
Impact factor: 2.368
Publication type: Letter or abstract
Authors: Blasco-Lucas, Arnau, Maldonado, Giuliana, Amador-Catalan, Amaya, Ferrer-Curriu, Gemma, Fuste, Berta, Perez, Maria L, Gonzalez-Alujas, Teresa, Beltran, Sergi, Comas-Riu, Jaume, Bardaji, Alfredo et al.
DOI: 10.1016/j.ejmg.2020.103854

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News

The consensus document is the result of multidisciplinary work that takes into account the risks associated with all stages of women's lives and the differences compared to men.

The study, which involved Vall d'Hebron, developed an action plan to efficiently allocate resources to patients most at risk of suffering this complication.

In light of this evidence, hospitals such as Vall d'Hebron have already started to include warnings about environmental pollution in their hospital discharge plans after a myocardial infarction.