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Cardiovascular Diseases

Cardiovascular Diseases group is a translational research group within the Cardiology Department of Vall d’Hebron Hospital that performs laboratory, clinical and epidemiological research. In the CIBERCV network we are within the topic of descriptor 2 “Arterial disease, thrombosis and myocardial ischemia-reperfusion injury”. Our contributions in these topics address the following lines: 

  • Myocardial ischemia-reperfusion injury (i.e. mechanisms of endogenous cardioprotection, ischemic conditioning and remodeling), 
  • Coronary artery disease (i.e. genetic factors involved in coronary artery disease, determinants of thrombotic complications and prognosis), 
  • Aortic diseases (i.e. determinants of aorta dilatation, aortic biomechanics abnormalities in Marfan´s syndrome, and new imaging methods), 
  • Congenital/familiar heart diseases (i.e. genetic determinants and prognosis factors). 

In the CIBERESP network, our group is interested in the study of effectiveness/cost-effectiveness of cardiovascular interventions, health outcome research and methods in clinical research. The group has 19 principal investigators, 32 active projects and clinical trial and has been done 142 publications in 2020.

Publications

Neurological event rates and associated risk factors in acute type B aortic dissections treated by thoracic aortic endovascular repair.

PMID: 35260280
Journal: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
Year: 2022
Reference: J Thorac Cardiovasc Surg. 2022 Feb 10. pii: S0022-5223(22)00131-3. doi: 10.1016/j.jtcvs.2022.02.007.
Impact factor: 5.209
Publication type: Paper in international publication
Authors: Bossone, Eduardo, Pai, Chih-Wen, Eagle, Kim, Sundt, Thoralf, Patel, Himanshu, Trimarchi, Santi, Eckstein, Hans-Henning, Schermerhorn, Marc, Estrera, Anthony, Chen, Edward P et al.
DOI: 10.1016/j.jtcvs.2022.02.007

CT or Invasive Coronary Angiography in Stable Chest Pain.

PMID: 35240010
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2022
Reference: N Engl J Med. 2022 Apr 28;386(17):1591-1602. doi: 10.1056/NEJMoa2200963. Epub 2022 Mar 4.
Impact factor: 91.253
Publication type: Paper in international publication
Authors: Rieckmann, Nina, Maurovich-Horvat, Pal, Bosserdt, Maria, Kofoed, Klaus F, Merkely, Bela, Knudsen, Andreas D, Benedek, Imre, Orr, Clare, Xavier Valente, Filipa, Zvaigzne, Ligita et al.
DOI: 10.1056/NEJMoa2200963

Defective dimerization of FoF1-ATP synthase secondary to glycation favors mitochondrial energy deficiency in cardiomyocytes during aging.

PMID: 35233924
Journal: AGING CELL
Year: 2022
Reference: Aging Cell. 2022 Mar;21(3):e13564. doi: 10.1111/acel.13564. Epub 2022 Mar 2.
Impact factor: 9.304
Publication type: Paper in international publication
Authors: Bou-Teen, Diana, Fernandez-Sanz, Celia, Miro-Casas, Elisabet, Nichtova, Zuzana, Bonzon-Kulichenko, Elena, Casos, Kelly, Inserte, Javier, Rodriguez-Sinovas, Antonio, Benito, Begona, Sheu, Shey-Shing et al.
DOI: 10.1111/acel.13564

Magnesium-based resorbable scaffold vs permanent metallic sirolimus-eluting stent in patients with ST-segment elevation myocardial infarction: 3-year results of the MAGSTEMI randomised controlled trial.

PMID: 35225793
Journal: EuroIntervention
Year: 2022
Reference: EuroIntervention. 2022 Feb 28. pii: EIJ-D-21-00651. doi: 10.4244/EIJ-D-21-00651.
Impact factor: 6.534
Publication type: Paper in international publication
Authors: Sabate, Manel, Cuesta, Javier, Ortega-Paz, Luis, Brugaletta, Salvatore, Gomez-Lara, Josep, Alfonso, Fernando, Cequier, Angel, Romani, Sebastian, Bordes, Pascual, Serra, Antonio et al.
DOI: 10.4244/EIJ-D-21-00651

Pulmonary Arterial Remodeling Is Related to the Risk Stratification and Right Ventricular-Pulmonary Arterial Coupling in Patients With Pulmonary Arterial Hypertension.

PMID: 34012405
Journal: Frontiers in Physiology
Year: 2021
Reference: Front Physiol. 2021 May 3;12:631326. doi: 10.3389/fphys.2021.631326. eCollection 2021.
Impact factor: 4.566
Publication type: Paper in international publication
Authors: Grignola, Juan C, Domingo, Enric, Lopez-Meseguer, Manuel, Trujillo, Pedro, Bravo, Carlos, Perez-Hoyos, Santiago, Roman, Antonio et al.
DOI: 10.3389/fphys.2021.631326

[Middle cerebral artery stroke due to paradoxical embolism in a patient with COVID-19 pneumonia].

PMID: 33362331
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2021
Reference: Rev Esp Cardiol. 2021 Jun;74(6):558-559. doi: 10.1016/j.recesp.2020.12.004. Epub 2020 Dec 19.
Impact factor: 4.753
Publication type: Letter whit IF
Authors: Pons-Pellice, Laura, Camio-Visauta, Elena, Prat, Ivette Chocron-Da, Fernando Rodriguez-Palomares, Jose, Noguer, Ferran Roses, Nadal, Miriam De et al.
DOI: 10.1016/j.recesp.2020.12.004

EVOLUCIÓN DEL INTERVALO QTC EN PACIENTES CON INFECCIÓN SARS-COV-2 TRATADOS CON FARMACOS ANTIVIRALES

PMID: 33995537
Journal: ANALES DE PEDIATRIA
Year: 2021
Reference: An Pediatr (Barc). 2021 Apr 20. pii: S1695-4033(21)00177-6. doi: 10.1016/j.anpedi.2021.04.009.
Impact factor: 1.5
Publication type: Paper in national publication
Authors: Esmel-Vilomara, Roger, Dolader, Paola, Sabate-Rotes, Anna, Soriano-Arandes, Antoni, Gran, Ferran, Roses-Noguer, Ferran et al.
DOI: 10.1016/j.anpedi.2021.04.009

Transient upper limb ischaemia during veno-arterial extracorporeal membrane oxygenation in a child.

PMID: 34000021
Journal: Interactive cardiovascular and thoracic surgery
Year: 2021
Reference: Interact Cardiovasc Thorac Surg. 2021 Oct 29;33(5):803-806. doi: 10.1093/icvts/ivab153.
Impact factor: 0
Publication type: Paper in international publication
Authors: Izquierdo-Blasco, Jaume, Riaza, Lucia, Pujol, Montse, Gran, Ferran, Fernandez-Doblas, Joaquin, Perez-Andreu, Joaquin, Abella, Raul F, Balcells, Joan et al.
DOI: 10.1093/icvts/ivab153

A novel clinical risk prediction model for myocardial infarction, coronary revascularization, and cardiac death according to clinical, exercise, and gated SPECT variables (VH-RS).

PMID: 31049558
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2020
Reference: Eur Heart J Cardiovasc Imaging. 2020 Feb 1;21(2):210-221. doi: 10.1093/ehjci/jez078.
Impact factor: 4.841
Publication type: Paper in international publication
Authors: Romero-Farina, Guillermo, Candell-Riera, Jaume, Aguade-Bruix, Santiago, Garcia Dorado, David et al.
DOI: 10.1093/ehjci/jez078

Translational issues for mitoprotective agents as adjunct to reperfusion therapy in patients with ST-segment elevation myocardial infarction.

PMID: 31967733
Journal: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Year: 2020
Reference: J Cell Mol Med. 2020 Mar;24(5):2717-2729. doi: 10.1111/jcmm.14953. Epub 2020 Jan 22.
Impact factor: 4.486
Publication type: Review in international publication
Authors: Botker, Hans Erik, Cabrera-Fuentes, Hector Alejandro, Ruiz-Meana, Marisol, Heusch, Gerd, Ovize, Michel et al.
DOI: 10.1111/jcmm.14953

Mosaic Bioprostheses May Mimic Infective Endocarditis by PET/CTA: Trust the Uptake Pattern to Avoid Misdiagnosis.

PMID: 31954645
Journal: JACC-Cardiovascular Imaging
Year: 2020
Reference: JACC Cardiovasc Imaging. 2020 Oct;13(10):2239-2244. doi: 10.1016/j.jcmg.2019.11.019. Epub 2020 Jan 15.
Impact factor: 12.74
Publication type: Paper in international publication
Authors: Cuellar-Calabria, Hug, Tornos, Pilar, Roque, Albert, Pizzi, Maria N, Fernandez-Hidalgo, Nuria, Gonzalez-Alujas, Maria Teresa, Rios, Remedios, Castell-Conesa, Joan, Escobar, Manuel, Ferreira-Gonzalez, Ignacio et al.
DOI: 10.1016/j.jcmg.2019.11.019

Modified LAMPOON technique.

PMID: 31932236
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2020
Reference: Rev Esp Cardiol (Engl Ed). 2020 Jul;73(7):579. doi: 10.1016/j.rec.2019.10.021. Epub 2020 Jan 10.
Impact factor: 4.642
Publication type: Paper in national publication
Authors: Gonzalez Sucarrats, Silvia, Serra Garcia, Vicenc, Marti Aguasca, Gerard et al.
DOI: 10.1016/j.rec.2019.10.021

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News

The consensus document is the result of multidisciplinary work that takes into account the risks associated with all stages of women's lives and the differences compared to men.

The study, which involved Vall d'Hebron, developed an action plan to efficiently allocate resources to patients most at risk of suffering this complication.

In light of this evidence, hospitals such as Vall d'Hebron have already started to include warnings about environmental pollution in their hospital discharge plans after a myocardial infarction.