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Clinical Neuroimmunology

The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches. 

Publications

Assessment of 2D conventional and synthetic MRI in multiple sclerosis.

PMID: 35583667
Journal: NEURORADIOLOGY
Year: 2022
Reference: Neuroradiology. 2022 May 18. pii: 10.1007/s00234-022-02973-2. doi: 10.1007/s00234-022-02973-2.
Impact factor: 2.804
Publication type: Paper in international publication
Authors: Aymerich, Francesc Xavier, Auger, Cristina, Alonso, Julio, Barros, Andrea, Clarke, Margareta A, Mora, Juan, Arrambide, Georgina, Corral, Juan Francisco, Andrino, Ana, Sastre-Garriga, Jaume et al.
DOI: 10.1007/s00234-022-02973-2

Exploring in vivo multiple sclerosis brain microstructural damage through T1w/T2w ratio: a multicentre study.

PMID: 35580993
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2022
Reference: J Neurol Neurosurg Psychiatry. 2022 Jul;93(7):741-752. doi: 10.1136/jnnp-2022-328908. Epub 2022 May 17.
Impact factor: 10.283
Publication type: Paper in international publication
Authors: Margoni, Monica, Pagani, Elisabetta, Meani, Alessandro, Storelli, Loredana, Mesaros, Sarlota, Drulovic, Jelena, Barkhof, Frederik, Vrenken, Hugo, Gallo, Antonio, Bisecco, Alvino et al.
DOI: 10.1136/jnnp-2022-328908

Two years of COVID-19 in the MS community: What have we learnt so far?

PMID: 35549532
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jun;28(7):1005-1008. doi: 10.1177/13524585221099844. Epub 2022 May 13.
Impact factor: 6.312
Publication type: Editorail in international publication
Authors: Thompson, Alan J, Montalban, Xavier, Zabalza, Ana et al.
DOI: 10.1177/13524585221099844

Inflammation in multiple sclerosis induces a specific reactive astrocyte state driving non-cell-autonomous neuronal damage.

PMID: 35538884
Journal: Clinical and Translational Medicine
Year: 2022
Reference: Clin Transl Med. 2022 May;12(5):e837. doi: 10.1002/ctm2.837.
Impact factor: 11.492
Publication type: Letter whit IF
Authors: Matute-Blanch, Clara, Brito, Veronica, Midaglia, Luciana, Villar, Luisa M, Garcia-Diaz Barriga, Gerardo, Guzman de la Fuente, Alerie, Borras, Eva, Fernandez-Garcia, Sara, Calvo-Barreiro, Laura, Miguez, Andres et al.
DOI: 10.1002/ctm2.837

Time Matters: Adjusted Analysis of the Influence of Direct Transfer to Angio-Suite Protocol in Functional Outcome.

PMID: 32390548
Journal: STROKE
Year: 2020
Reference: Stroke. 2020 Jun;51(6):1766-1771. doi: 10.1161/STROKEAHA.119.028586. Epub 2020 May 11.
Impact factor: 7.19
Publication type: Paper in international publication
Authors: Rubiera, Marta, Molina, Carlos A, Tomasello, Alejandro, Ribo, Marc, Hernandez, David, Rodriguez-Luna, David, Pagola, Jorge, Coscojuela, Pilar, Requena, Manuel, Olive, Marta et al.
DOI: 10.1161/STROKEAHA.119.028586

[12th Post-ECTRIMS Meeting: review of the novelties from the 2019 ECTRIMS Congress (I)].

PMID: 32390131
Journal: REVISTA DE NEUROLOGIA
Year: 2020
Reference: Rev Neurol. 2020 May 16;70(10):379-390. doi: 10.33588/rn.7010.2020121.
Impact factor: 0.562
Publication type: Review in national publication
Authors: Prieto, J M, Fernandez, O, Aladro, Y, Arroyo, R, Brieva, Ll, Calles-Hernandez, M C, Carrascal, P, Comabella, M, Costa-Frossard, L, Eichau, S et al.
DOI: 10.33588/rn.7010.2020121

Reduced dynamics of functional connectivity and cognitive impairment in multiple sclerosis.

PMID: 30887862
Journal: Multiple Sclerosis Journal
Year: 2020
Reference: Mult Scler. 2020 Apr;26(4):476-488. doi: 10.1177/1352458519837707. Epub 2019 Mar 19.
Impact factor: 5.412
Publication type: Paper in international publication
Authors: Koini, Marisa, d'Ambrosio, Alessandro, Valsasina, Paola, Gallo, Antonio, De Stefano, Nicola, Pareto, Deborah, Barkhof, Frederik, Ciccarelli, Olga, Enzinger, Christian, Tedeschi, Gioacchino et al.
DOI: 10.1177/1352458519837707

A validation study of manual atrophy measures in patients with Multiple Sclerosis.

PMID: 32246177
Journal: NEURORADIOLOGY
Year: 2020
Reference: Neuroradiology. 2020 Aug;62(8):955-964. doi: 10.1007/s00234-020-02401-3. Epub 2020 Apr 3.
Impact factor: 2.238
Publication type: Paper in international publication
Authors: Cappelle, Sarah, Pareto, Deborah, Tintore, Mar, Alyafeai, Rumaiza, Vidal-Jordana, Angela, Alberich, Manel, Sastre-Garriga, Jaume, Auger, Cristina, Montalban, Xavier, Rovira, Alex et al.
DOI: 10.1007/s00234-020-02401-3

Blog

News

In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.

The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.

Rates

Simoa HD1 equipment

We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis

We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.

More information