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Clinical Neuroimmunology

The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches. 

Publications

Long-term safety and efficacy of ozanimod in relapsing multiple sclerosis: Up to 5 years of follow-up in the DAYBREAK open-label extension trial.

PMID: 35765217
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jun 28:13524585221102584. doi: 10.1177/13524585221102584.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Sheffield, James K; Minton, Neil; Cheng, Chun-Yen; Silva, Diego; Kappos, Ludwig; Cohen, Jeffrey A; Havrdova, Eva K; Montalban, Xavier; Hartung, Hans-Peter; Cree, Bruce Ac et al.
DOI: 10.1177/13524585221102584

Immunotherapy for people with clinically isolated syndrome or relapsing-remitting multiple sclerosis: treatment response by demographic, clinical, and biomarker subgroups (PROMISE)-a systematic review protocol.

PMID: 35778721
Journal: Systematic Reviews
Year: 2022
Reference: Syst Rev. 2022 Jul 1;11(1):134. doi: 10.1186/s13643-022-01997-2.
Impact factor: 2.522
Publication type: Paper in international publication
Authors: Rahn, Anne C; Heesen, Christoph; Fittipaldo, Andrea V; Chard, Declan; Rio, Jordi; Kopke, Sascha; Rover, Christian; Lehnert, Thomas; Friede, Tim et al.
DOI: 10.1186/s13643-022-01997-2

The role of specialist nurses in detecting spasticity and related symptoms in multiple sclerosis.

PMID: 35799407
Journal: JOURNAL OF CLINICAL NURSING
Year: 2022
Reference: J Clin Nurs. 2022 Jul 7. doi: 10.1111/jocn.16421.
Impact factor: 3.036
Publication type: Paper in international publication
Authors: Artola, Montse; Sola-Valls, Nuria; Saiz, Albert; Montero, Laura; Fornali, Olga; Mercade, Laura; Matamoros, Mandi; Molinos, Consuelo; Leon, Isabel; Zabay, Cinta et al.
DOI: 10.1111/jocn.16421

Fitbeat: COVID-19 Estimation Based on Wristband Heart Rate Using a Contrastive Convolutional Auto-Encoder.

PMID: 34720200
Journal: PATTERN RECOGNITION
Year: 2022
Reference: Pattern Recognit. 2022 Mar;123:108403. doi: 10.1016/j.patcog.2021.108403. Epub 2021 Oct 26.
Impact factor: 7.74
Publication type: Paper in international publication
Authors: Liu, Shuo; Han, Jing; Puyal, Estela Laporta; Kontaxis, Spyridon; Sun, Shaoxiong; Locatelli, Patrick; Dineley, Judith; Pokorny, Florian B; Costa, Gloria Dalla; Leocani, Letizia et al.
DOI: 10.1016/j.patcog.2021.108403

Initial studies with [(11)C]vorozole positron emission tomography detect over-expression of intra-tumoral aromatase in breast cancer.

PMID: 31757843
Journal: JOURNAL OF NUCLEAR MEDICINE
Year: 2020
Reference: J Nucl Med. 2020 Jun;61(6):807-813. doi: 10.2967/jnumed.119.231589. Epub 2019 Nov 22.
Impact factor: 7.887
Publication type: Paper in international publication
Authors: Shroyer, Kenneth R, Franceschi, Dinko, Dhawan, Jasbeer, Tahmi, Mouna, Pareto, Deborah, Bonilla, Patrick, Airola, Krystal, Cohen, Jules, Biegon, Anat et al.
DOI: 10.2967/jnumed.119.231589

Sex Differences and Commonalities in the Impact of a Palatable Meal on Thalamic and Insular Connectivity.

PMID: 32492812
Journal: Nutrients
Year: 2020
Reference: Nutrients. 2020 Jun 1;12(6). pii: nu12061627. doi: 10.3390/nu12061627.
Impact factor: 4.546
Publication type: Paper in international publication
Authors: Kilpatrick, Lisa, Pribic, Teodora, Ciccantelli, Barbara, Malagelada, Carolina, Livovsky, Dan M, Accarino, Anna, Pareto, Deborah, Azpiroz, Fernando, Mayer, Emeran A et al.
DOI: 10.3390/nu12061627

Assessment of brain volumes obtained from MP-RAGE and MP2RAGE images, quantified using different segmentation methods.

PMID: 32468150
Journal: MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
Year: 2020
Reference: MAGMA. 2020 Dec;33(6):757-767. doi: 10.1007/s10334-020-00854-4. Epub 2020 May 28.
Impact factor: 1.956
Publication type: Paper in international publication
Authors: Alonso, Juli, Pareto, Deborah, Alberich, Manel, Kober, Tobias, Marechal, Benedicte, Llado, Xavier, Rovira, Alex et al.
DOI: 10.1007/s10334-020-00854-4

EAN guideline on palliative care of people with severe, progressive multiple sclerosis.

PMID: 32469447
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2020
Reference: Eur J Neurol. 2020 Aug;27(8):1510-1529. doi: 10.1111/ene.14248. Epub 2020 May 29.
Impact factor: 4.516
Publication type: Paper in international publication
Authors: Sastre-Garriga, J, Kopke, S, Rahn, A C, Kleiter, I, Aleksovska, K, Battaglia, M A, Bay, J, Copetti, M, Drulovic, J, Kooij, L et al.
DOI: 10.1111/ene.14248

Blog

News

In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.

The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.

Rates

Simoa HD1 equipment

We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis

We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.

More information