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Clinical Neuroimmunology

The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches. 

Publications

Disease modifying therapy switching in relapsing multiple sclerosis: A Delphi consensus of the demyelinating expert group of the Spanish society of neurology.

PMID: 35512501
Journal: Multiple Sclerosis and Related Disorders
Year: 2022
Reference: Mult Scler Relat Disord. 2022 Jul;63:103805. doi: 10.1016/j.msard.2022.103805. Epub 2022 Apr 12.
Impact factor: 4.339
Publication type: Paper in international publication
Authors: Costa-Frossard, Lucienne, Gonzalez Platas, Montserrat, Pascual, Lamberto Landete, Llaneza-Gonzalez, Miguel, Gines, Maria Luisa Martinez, Matias-Guiu, Jorge, Meca-Lallana, Jose E, Bilbao, Mar Mendibe, Sempere, Angel Perez, Romero-Pinel, Lucia et al.
DOI: 10.1016/j.msard.2022.103805

Angioplasty with a stent retriever to treat vasospasm secondary to subarachnoid hemorrhage due to an aneurysm: a multicenter study of safety and efficacy.

PMID: 35504675
Journal: Radiologia
Year: 2022
Reference: Radiologia. 2022 Mar-Apr;64(2):103-109. doi: 10.1016/j.rxeng.2020.04.009.
Impact factor: 0
Publication type: Paper in international publication
Authors: Remollo, S, Lopez-Rueda, A, Vargas, A, Pinana, C, Chirife, O, Werner, M, Aja, L, Tomasello, Y A et al.
DOI: 10.1016/j.rxeng.2020.04.009

Combined technique as first approach in mechanical thrombectomy: Efficacy and safety of REACT catheter combined with stent retriever.

PMID: 35491662
Journal: INTERVENTIONAL NEURORADIOLOGY
Year: 2022
Reference: Interv Neuroradiol. 2022 May 2:15910199221095798. doi: 10.1177/15910199221095798.
Impact factor: 1.61
Publication type: Paper in international publication
Authors: Requena, Manuel, Pinana, Carlos, Olive-Gadea, Marta, Hernandez, David, Boned, Sandra, De Dios, Marta, Rodrigo, Marc, Rivera, Eila, Muchada, Marian, Cuevas, Jose Luis et al.
DOI: 10.1177/15910199221095798

Serum neurofilament light chain levels predict long-term disability progression in patients with progressive multiple sclerosis.

PMID: 35487685
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2022
Reference: J Neurol Neurosurg Psychiatry. 2022 Apr 29. pii: jnnp-2022-329020. doi: 10.1136/jnnp-2022-329020.
Impact factor: 10.283
Publication type: Paper in international publication
Authors: Comabella, Manuel, Sastre-Garriga, Jaume, Carbonell-Mirabent, Pere, Fissolo, Nicolas, Tur, Carmen, Malhotra, Sunny, Pareto, Deborah, Aymerich, Francesc X, Rio, Jordi, Rovira, Alex et al.
DOI: 10.1136/jnnp-2022-329020

Testing the Food Experience in Healthy Human Volunteers: a Proof-of-Concept Study.

PMID: 32176761
Journal: Journal of Gastrointestinal and Liver Diseases
Year: 2020
Reference: J Gastrointestin Liver Dis. 2020 Mar 13;29(1):65-68. doi: 10.15403/jgld-806.
Impact factor: 2.351
Publication type: Paper in international publication
Authors: Pribic, Teodora, Lopez, Quiro, Lucas, Eduardo, Livovsky, Dan M, Rovira, Alex, Accarino, Anna, Azpiroz, Fernando, Pareto, Deborah et al.
DOI: 10.15403/jgld-806

Ratio of T1-Weighted to T2-Weighted Signal Intensity as a Measure of Tissue Integrity: Comparison with Magnetization Transfer Ratio in Patients with Multiple Sclerosis.

PMID: 32139431
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2020
Reference: AJNR Am J Neuroradiol. 2020 Mar;41(3):461-463. doi: 10.3174/ajnr.A6481. Epub 2020 Mar 5.
Impact factor: 3.381
Publication type: Paper in international publication
Authors: Pareto, D, Garcia-Vidal, A, Alberich, M, Auger, C, Montalban, X, Tintore, M, Sastre-Garriga, J, Rovira, A et al.
DOI: 10.3174/ajnr.A6481

A fully convolutional neural network for new T2-w lesion detection in multiple sclerosis.

PMID: 31918065
Journal: NeuroImage-Clinical
Year: 2020
Reference: Neuroimage Clin. 2020;25:102149. doi: 10.1016/j.nicl.2019.102149. Epub 2019 Dec 28.
Impact factor: 4.35
Publication type: Paper in international publication
Authors: Salem, Mostafa, Valverde, Sergi, Cabezas, Mariano, Pareto, Deborah, Oliver, Arnau, Salvi, Joaquim, Rovira, Alex, Llado, Xavier et al.
DOI: 10.1016/j.nicl.2019.102149

MAGNIMS consensus recommendations on the use of brain and spinal cord atrophy measures in clinical practice.

PMID: 32094485
Journal: Nature Reviews Neurology
Year: 2020
Reference: Nat Rev Neurol. 2020 Mar;16(3):171-182. doi: 10.1038/s41582-020-0314-x. Epub 2020 Feb 24.
Impact factor: 27
Publication type: Review in international publication
Authors: Palace, Jackie, Sastre-Garriga, Jaume, Pareto, Deborah, Battaglini, Marco, Rocca, Maria A, Ciccarelli, Olga, Enzinger, Christian, Wuerfel, Jens, Sormani, Maria P, Barkhof, Frederik et al.
DOI: 10.1038/s41582-020-0314-x

Blog

News

In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.

The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.

Rates

Simoa HD1 equipment

We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis

We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.

More information