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Headache and Neurological Pain

Our research group is focused on studying the pathophysiology of migraine and other primary headaches using preclinical, translational and clinical research.

Migraine will allow us to define the brain’s adaptive, sensory/cognitive functions, through genetics, epigenetics, neurophysiology, neuromolecular and neuroanatomical information with an interest in developing clinical therapeutic solutions, with the goal on having an impact on suffering and increasing the well-being.

Publications

Salivary CGRP can monitor the different migraine phases: CGRP (in)dependent attacks.

PMID: 34601944
Journal: CEPHALALGIA
Year: 2022
Reference: Cephalalgia. 2022 Mar;42(3):186-196. doi: 10.1177/03331024211040467. Epub 2021 Oct 4.
Impact factor:
Publication type: Paper in international publication
Authors: Alpuente, Alicia; Asskour, Laila; Caronna, Edoardo; Gallardo, Victor J; Pozo-Rosich, Patricia; Torres-Ferrus, Marta et al.
DOI: 10.1177/03331024211040467

Board Walk - April 2022.

PMID: 35383491
Journal: CEPHALALGIA
Year: 2022
Reference: Cephalalgia. 2022 Apr;42(4-5):427-429. doi: 10.1177/03331024211070712.
Impact factor:
Publication type: Editorail in international publication
Authors: Pozo-Rosich, Patricia et al.
DOI: 10.1177/03331024211070712

Introduction to the cognitive hospital.

PMID: 35372780
Journal: Future healthcare journal
Year: 2022
Reference: Future Healthc J. 2022 Mar;9(1):34-40. doi: 10.7861/fhj.2021-0016.
Impact factor:
Publication type: Paper in international publication
Authors: Carbonell-Cobo, Marta; Chaudry, Zafar; Emery, Lisa; Garcia-Cuyas, Francesc; Gates, Darren; Hennessey, Iain; Hueto-Madrid, Juan Antonio; Moz, Monica; Patt, Carol; Pozo-Rosich, Patricia et al.
DOI: 10.7861/fhj.2021-0016

Epidemiology, work and economic impact of migraine in a large hospital cohort: time to raise awareness and promote sustainability.

PMID: 34282471
Journal: JOURNAL OF NEUROLOGY
Year: 2022
Reference: J Neurol. 2022 Mar;269(3):1456-1462. doi: 10.1007/s00415-021-10715-2. Epub 2021 Jul 20.
Impact factor:
Publication type: Paper in international publication
Authors: Alpuente, Alicia; Caronna, Edoardo; Gallardo, Victor Jose; Pozo-Rosich, Patricia; Torres-Ferrus, Marta et al.
DOI: 10.1007/s00415-021-10715-2

Impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the Spanish Atlas.

PMID: 33859216
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Apr 15;11(1):8286. doi: 10.1038/s41598-021-87352-2.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre-Vazquez, M; Colomina, I; Correa-Fernandez, J; Garrido-Cumbrera, M; Irimia, P; Pozo-Rosich, P; Santos-Lasaosa, S et al.
DOI: 10.1038/s41598-021-87352-2

How does the brain change in chronic migraine? Developing disease biomarkers.

PMID: 33291995
Journal: CEPHALALGIA
Year: 2021
Reference: Cephalalgia. 2021 Apr;41(5):613-630. doi: 10.1177/0333102420974359. Epub 2020 Dec 8.
Impact factor:
Publication type: Review in international publication
Authors: Coppola, Gianluca; Pascual, Julio; Pozo-Rosich, Patricia; Schwedt, Todd J et al.
DOI: 10.1177/0333102420974359

Migraine: epidemiology and systems of care.

PMID: 33773613
Journal: LANCET
Year: 2021
Reference: Lancet. 2021 Apr 17;397(10283):1485-1495. doi: 10.1016/S0140-6736(20)32160-7. Epub 2021 Mar 25.
Impact factor:
Publication type: Review in international publication
Authors: Ashina, Messoud; Ashina, Sait; Buse, Dawn C; Do, Thien Phu; Katsarava, Zaza; Krymchantowski, Abouch V; Lebedeva, Elena R; Lipton, Richard B; Ozge, Aynur; Pozo-Rosich, Patricia et al.
DOI: 10.1016/S0140-6736(20)32160-7

Migraine: integrated approaches to clinical management and emerging treatments.

PMID: 33773612
Journal: LANCET
Year: 2021
Reference: Lancet. 2021 Apr 17;397(10283):1505-1518. doi: 10.1016/S0140-6736(20)32342-4. Epub 2021 Mar 25.
Impact factor:
Publication type: Review in international publication
Authors: Ashina, Hakan; Ashina, Messoud; Buse, Dawn C; Do, Thien Phu; Dodick, David W; Halker Singh, Rashmi; Lee, Mi Ji; Mitsikostas, Dimos D; Peres, Mario F P; Pozo-Rosich, Patricia et al.
DOI: 10.1016/S0140-6736(20)32342-4

Persistent post-traumatic headache: a migrainous loop or not? The preclinical evidence.

PMID: 32664898
Journal: JOURNAL OF HEADACHE AND PAIN
Year: 2020
Reference: J Headache Pain. 2020 Jul 14;21(1):90. doi: 10.1186/s10194-020-01135-0.
Impact factor: 4.797
Publication type: Review in international publication
Authors: Caronna, Edoardo, Benemei, Silvia, Labastida-Ramirez, Alejandro, Abramova, Ekaterina, Brunelli, Nicoletta, Diana, Paola, Gapeshin, Roman, Hofacker, Maxi Dana, Pias, Enrique Martinez, Maestrini, Ilaria et al.
DOI: 10.1186/s10194-020-01135-0

Impact of Puberty in Pediatric Migraine: A Pilot Prospective Study.

PMID: 32657062
Journal: Journal of Clinical Neurology
Year: 2020
Reference: J Clin Neurol. 2020 Jul;16(3):416-422. doi: 10.3988/jcn.2020.16.3.416.
Impact factor: 2.439
Publication type: Paper in international publication
Authors: Fonseca, Elena, Macaya, Alfons, Pozo-Rosich, Patricia, Gallardo, Victor Jose, Torres-Ferrus, Marta et al.
DOI: 10.3988/jcn.2020.16.3.416

Influence of headache pain intensity and frequency on migraine-related disability in chronic migraine patients treated with OnabotulinumtoxinA.

PMID: 32652924
Journal: JOURNAL OF HEADACHE AND PAIN
Year: 2020
Reference: J Headache Pain. 2020 Jul 11;21(1):88. doi: 10.1186/s10194-020-01157-8.
Impact factor: 4.797
Publication type: Paper in international publication
Authors: Torres-Ferrus, Marta, Gallardo, Victor Jose, Alpuente, Alicia, Pozo-Rosich, Patricia et al.
DOI: 10.1186/s10194-020-01157-8

Long-term prognosis related to deep sedation in refractory status epilepticus.

PMID: 32614067
Journal: ACTA NEUROLOGICA SCANDINAVICA
Year: 2020
Reference: Acta Neurol Scand. 2020 Dec;142(6):555-562. doi: 10.1111/ane.13302. Epub 2020 Jul 29.
Impact factor: 2.684
Publication type: Paper in international publication
Authors: Caronna, Edoardo, Sanchez Corral, Anna, Santafe, Manel, Sueiras, Maria, Guzman, Lorena, Quintana, Manuel, Toledo-Argany, Manuel, Santamarina, Estevo, Gracia Gozalo, Rosa Maria, Vilaseca, Andreu et al.
DOI: 10.1111/ane.13302

Blog

News

Two international studies led by Vall d'Hebron recommend early administration of specific drugs to prevent migraine to achieve a better response to therapy.

On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.

The study, conducted in more than 770 people, concludes that atogepant reduces the frequency of migraine attacks and the need to take medication.