About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is focused on studying the pathophysiology of migraine and other primary headaches using preclinical, translational and clinical research.
Migraine will allow us to define the brain’s adaptive, sensory/cognitive functions, through genetics, epigenetics, neurophysiology, neuromolecular and neuroanatomical information with an interest in developing clinical therapeutic solutions, with the goal on having an impact on suffering and increasing the well-being.
PMID: 37786502 Journal: Future healthcare journal Year: 2023 Reference: Future Healthc J. 2023 Mar;10(1):46-49. doi: 10.7861/fhj.2022-0142. Impact factor: Publication type: Paper in international publication Authors: Aguilar, Anna Ochoa de Echaguen; Carbonell-Cobo, Marta; de Castro, Rodolfo; Hueto-Madrid, Juan Antonio; Paradell, Raquel Canovas; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Rovira-Simon, Jordi; Sales-I-Coll, Marc; Shaw, Genevieve et al. DOI: 10.7861/fhj.2022-0142
PMID: 37791410 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2023 Reference: Eur J Neurol. 2023 Oct 4. doi: 10.1111/ene.16058. Impact factor: Publication type: Paper in international publication Authors: Alpuente, Alicia; Alpuente, Alicia; Caronna, Edoardo; Elosua-Bayes, Iker; Gallardo, Victor J; Gallardo, Victor J; Melgarejo, Laura; Melgarejo, Laura; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia et al. DOI: 10.1111/ene.16058
PMID: 37795746 Journal: HEADACHE Year: 2023 Reference: Headache. 2023 Oct 5. doi: 10.1111/head.14629. Impact factor: Publication type: Paper in international publication Authors: Buse, Dawn C; Dabruzzo, Brett; Fanning, Kristina M; Lipton, Richard B; Orr, Serena L; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Reed, Michael L et al. DOI: 10.1111/head.14629
PMID: 37802552 Journal: Neurologia Year: 2023 Reference: Neurologia (Engl Ed). 2023 Oct;38(8):541-549. doi: 10.1016/j.nrleng.2021.02.009. Impact factor: Publication type: Paper in international publication Authors: Bohorquez, S; Camina, J; Diaz de Teran, J; Gago-Veiga, A; Gallardo, V J; Gallardo, V J; Gonzalez-Garcia, N; Gonzalez-Quintanilla, V; Gonzalez-Quintanilla, V; Lopez-Veloso, A C et al. DOI: 10.1016/j.nrleng.2021.02.009
PMID: 35716692 Journal: LANCET NEUROLOGY Year: 2022 Reference: Lancet Neurol. 2022 Jul;21(7):597-607. doi: 10.1016/S1474-4422(22)00185-5. Impact factor: Publication type: Paper in international publication Authors: Ashina, Messoud; Christoffersen, Cecilie Laurberg; Ettrup, Anders; Josiassen, Mette Krog; Lanteri-Minet, Michel; Phul, Ravinder; Pozo-Rosich, Patricia; Sperling, Bjorn et al. DOI: 10.1016/S1474-4422(22)00185-5
PMID: 35678104 Journal: PSYCHOPHYSIOLOGY Year: 2022 Reference: Psychophysiology. 2022 Nov;59(11):e14108. doi: 10.1111/psyp.14108. Epub 2022 Jun 9. Impact factor: Publication type: Paper in international publication Authors: Marti-Marca, Angela; Pozo-Rosich, Patricia; Soto-Faraco, Salvador; Torralba Cuello, Mireia; Vila-Ballo, Adria et al. DOI: 10.1111/psyp.14108
PMID: 35675076 Journal: JAMA Network Open Year: 2022 Reference: JAMA Netw Open. 2022 Jun 1;5(6):e2215499. doi: 10.1001/jamanetworkopen.2022.15499. Impact factor: Publication type: Paper in international publication Authors: Blumenfeld, Andrew M; Dabruzzo, Brett; Dodick, David W; Finnegan, Michelle; Li, Ye; Lipton, Richard B; Lu, Kaifeng; McAllister, Peter; Miceli, Rosa; Pozo-Rosich, Patricia et al. DOI: 10.1001/jamanetworkopen.2022.15499
PMID: 35670131 Journal: HEADACHE Year: 2022 Reference: Headache. 2022 Jun;62(6):648-649. doi: 10.1111/head.14330. Epub 2022 Jun 7. Impact factor: Publication type: Letter or abstract Authors: Caronna, Edoardo; Pozo-Rosich, Patricia et al. DOI: 10.1111/head.14330
PMID: 34145431 Journal: Nature Reviews Neurology Year: 2021 Reference: Nat Rev Neurol. 2021 Aug;17(8):501-514. doi: 10.1038/s41582-021-00509-5. Epub 2021 Jun 18. Impact factor: Publication type: Review in international publication Authors: Arons, Mihails; Ashina, Hakan; Ashina, Messoud; Braschinsky, Mark; Daniel, Oved; Del Rio, Margarita Sanchez; Diener, Hans-Christoph; Ducros, Anne; Eigenbrodt, Anna K; Katsarava, Zaza et al. DOI: 10.1038/s41582-021-00509-5
PMID: 34030634 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2021 Reference: J Headache Pain. 2021 May 24;22(1):43. doi: 10.1186/s10194-021-01258-y. Impact factor: Publication type: Paper in international publication Authors: Alpuente Ruiz, A; Frattale, I; Gago-Veiga, A B; Gallardo, V J; Gryglas-Dworak, A; Huhn, J-I; Latysheva, N; Marques, I B; Ornello, R; Pozo-Rosich, P et al. DOI: 10.1186/s10194-021-01258-y
PMID: 34006218 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2021 Reference: J Headache Pain. 2021 May 18;22(1):39. doi: 10.1186/s10194-021-01252-4. Impact factor: Publication type: Paper in international publication Authors: Abdelrahman, Tagwa; Abobaker Hamza, Salih Boushra; Abramova, Ekaterina; Abu-Arafeh, Ishaq; Akhmadeeva, Leila; Albanese, Maria; Aloman, Stefan; Amin, Faisal Mohammad; Antic, Sonja; Antonaci, Fabio et al. DOI: 10.1186/s10194-021-01252-4
PMID: 33990161 Journal: CEPHALALGIA Year: 2021 Reference: Cephalalgia. 2021 Oct;41(11-12):1135-1151. doi: 10.1177/03331024211010413. Epub 2021 May 14. Impact factor: Publication type: Paper in international publication Authors: Ashina, Messoud; Deen, Marie; Diener, Hans-Christoph; Dodick, David W; Goadsby, Peter J; Hoek, Thomas van den; Jensen, Rigmor H; Magis, Delphine; Martinelli, Daniele; Pozo-Rosich, Patricia et al. DOI: 10.1177/03331024211010413
PMID: 32349653 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2020 Reference: J Headache Pain. 2020 Apr 29;21(1):42. doi: 10.1186/s10194-020-01111-8. Impact factor: Publication type: Review in international publication Authors: Alpuente-Ruiz, A; Brunello, F; Chiappino, D; de Vries, T; Di Marco, S; Ferlisi, S; Gonzalez-Garcia, N; Gonzalez-Martinez, A; Guerritore, L; Khutorov, D et al. DOI: 10.1186/s10194-020-01111-8
PMID: 31757168 Journal: CEPHALALGIA Year: 2020 Reference: Cephalalgia. 2020 Apr;40(4):411-412. doi: 10.1177/0333102419885375. Epub 2019 Nov 22. Impact factor: Publication type: Letter whit IF Authors: Pozo-Rosich, Patricia; Torres-Ferrus, Marta et al. DOI: 10.1177/0333102419885375
PMID: 32086801 Journal: HEADACHE Year: 2020 Reference: Headache. 2020 Apr;60(4):677-685. doi: 10.1111/head.13765. Epub 2020 Feb 22. Impact factor: Publication type: Paper in international publication Authors: Alpuente, Alicia; Alvarez-Sabin, Jose; Gallardo, Victor Jose; Pozo-Rosich, Patricia; Torres-Ferrus, Marta et al. DOI: 10.1111/head.13765
PMID: 32068897 Journal: HEADACHE Year: 2020 Reference: Headache. 2020 May;60(5):916-928. doi: 10.1111/head.13774. Epub 2020 Feb 18. Impact factor: Publication type: Paper in international publication Authors: Alpuente, Alicia; Caronna, Edoardo; Fonseca, Elena; Gallardo, Victor Jose; Gomez-Galvan, Juan Bernardo; Pozo-Rosich, Patricia; Torres-Ferrus, Marta et al. DOI: 10.1111/head.13774
PMID: 30687919 Journal: REVISTA DE NEUROLOGIA Year: 2019 Reference: Rev Neurol. 2019 Feb 1;68(3):118-122. Impact factor: Publication type: Paper in national publication Authors: Carrillo, I; Guerrero-Peral, A L; Guilabert, M; Ignacio, E; Mira, J J; Pascual, J; Porta-Etessam, J; Pozo-Rosich, P et al. DOI: 10.33588/rn.6803.2018293
PMID: 30929913 Journal: Neurologia (Barcelona, Spain) Year: 2019 Reference: Neurologia (Engl Ed). 2019 Mar 28:S0213-4853(19)30024-6. doi: 10.1016/j.nrl.2018.12.006. Impact factor: Publication type: Review in national publication Authors: Camina Muniz, J; Gago-Veiga, A B; Garcia-Azorin, D; Gonzalez-Quintanilla, V; Ordas, C M; Pozo-Rosich, P; Santos-Lasaosa, S; Torres-Ferrus, M; Viguera-Romero, J et al. DOI: 10.1016/j.nrl.2018.12.006
PMID: 31326215 Journal: Neurologia (Barcelona, Spain) Year: 2019 Reference: Neurologia (Engl Ed). 2019 Jul 17:S0213-4853(19)30075-1. doi: 10.1016/j.nrl.2019.03.013. Impact factor: Publication type: Review in national publication Authors: Belvis, R; Cuadrado, M L; Diaz-Insa, S; Gago-Veiga, A; Guerrero-Peral, A L; Huerta, M; Irimia, P; Lainez, J M; Latorre, G; Leira, R et al. DOI: 10.1016/j.nrl.2019.03.013
PMID: 31513849 Journal: NEUROBIOLOGY OF LEARNING AND MEMORY Year: 2019 Reference: Neurobiol Learn Mem. 2019 Dec;166:107085. doi: 10.1016/j.nlm.2019.107085. Epub 2019 Sep 9. Impact factor: 3.01 Publication type: Paper in international publication Authors: Salmi, Juha, Vila-Ballo, Adria, Soveri, Anna, Rostan, Carles, Rodriguez-Fornells, Antoni, Lehtonen, Minna, Laine, Matti et al. DOI: 10.1016/j.nlm.2019.107085
PMID: 30386285 Journal: Frontiers in Neurology Year: 2018 Reference: Front Neurol. 2018 Oct 16;9:808. doi: 10.3389/fneur.2018.00808. eCollection 2018. Impact factor: 3.508 Publication type: Paper in international publication Authors: Caronna, Edoardo, Gallardo, Victor Jose, Hernandez-Beltran, Natalia, Torres-Ferrus, Marta, Pozo-Rosich, Patricia et al. DOI: 10.3389/fneur.2018.00808
PMID: 30384104 Journal: EPILEPSY & BEHAVIOR Year: 2018 Reference: Epilepsy Behav. 2018 Dec;89:8-14. doi: 10.1016/j.yebeh.2018.09.046. Epub 2018 Oct 26. Impact factor: 2.6 Publication type: Paper in international publication Authors: Santamarina, Estevo, Parejo, Beatriz, Abraira, Laura, Gutierrez-Viedma, Alvaro, Alpuente, Alicia, Abarrategui, Belen, Toledo, Manuel, Mazuela, Gonzalo, Salas-Puig, Xavier, Garcia-Morales, Irene et al. DOI: 10.1016/j.yebeh.2018.09.046
PMID: 30143565 Journal: NEUROLOGY Year: 2018 Reference: Neurology. 2018 Sep 25;91(13):622-624. doi: 10.1212/WNL.0000000000006251. Epub 2018 Aug 24. Impact factor: 8.055 Publication type: Paper in international publication Authors: Midaglia, Luciana, Gratacos, Margarida, Caronna, Edoardo, Raguer, Nuria, Sastre-Garriga, Jaume, Montalban, Xavier, Tintore, Mar et al. DOI: 10.1212/WNL.0000000000006251
PMID: 29339147 Journal: BIOLOGICAL PSYCHOLOGY Year: 2018 Reference: Biol Psychol. 2018 Feb;132:233-243. doi: 10.1016/j.biopsycho.2018.01.007. Epub 2018 Jan 12. Impact factor: 2.891 Publication type: Paper in international publication Authors: Vila-Ballo, Adria, Salmi, Juha, Soveri, Anna, Lehtonen, Minna, Laine, Matti, Rodriguez-Fornells, Antoni et al. DOI: 10.1016/j.biopsycho.2018.01.007
Two international studies led by Vall d'Hebron recommend early administration of specific drugs to prevent migraine to achieve a better response to therapy.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
The study, conducted in more than 770 people, concludes that atogepant reduces the frequency of migraine attacks and the need to take medication.
