About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is focused on studying the pathophysiology of migraine and other primary headaches using preclinical, translational and clinical research.
Migraine will allow us to define the brain’s adaptive, sensory/cognitive functions, through genetics, epigenetics, neurophysiology, neuromolecular and neuroanatomical information with an interest in developing clinical therapeutic solutions, with the goal on having an impact on suffering and increasing the well-being.
PMID: 35166156 Journal: CEPHALALGIA Year: 2022 Reference: Cephalalgia. 2022 Jul;42(8):804-809. doi: 10.1177/03331024211068074. Epub 2022 Feb 15. Impact factor: Publication type: Paper in international publication Authors: Ballve, Alejandro; Caronna, Edoardo; Cornejo, Ana; de Lorenzo, Inigo; Diaz-de-Teran, Javier; Gago-Veiga, Ana Beatriz; Gallardo, Victor J; Garcia-Azorin, David; Gonzalez-Garcia, Nuria; Gonzalez-Martinez, Alicia et al. DOI: 10.1177/03331024211068074
PMID: 34535428 Journal: NEUROLOGIA Year: 2022 Reference: Neurologia. 2022 Jan-Feb;37(1):1-12. doi: 10.1016/j.nrleng.2018.12.023. Epub 2021 Sep 14. Impact factor: Publication type: Paper in national publication Authors: Diaz de Teran, J; Gago-Veiga, A B; Gonzalez-Garcia, N; Lopez-Veloso, A C; Mas-Sala, N; Minguez-Olaondo, A; Pozo-Rosich, P; Ruiz-Pinero, M; Santos-Lasaosa, S; Viguera-Romero, J et al. DOI: 10.1016/j.nrl.2018.12.003
PMID: 34600443 Journal: BRITISH JOURNAL OF PHARMACOLOGY Year: 2022 Reference: Br J Pharmacol. 2022 Feb;179(3):358-370. doi: 10.1111/bph.15699. Epub 2021 Nov 16. Impact factor: Publication type: Paper in international publication Authors: Goadsby, Peter J; Holland, Philip R; Johnson, Kirk W; Loraine, Howard J; Murdock, Paul R; Page, Keith; Vila-Pueyo, Marta; Woodrooffe, Amanda J et al. DOI: 10.1111/bph.15699
PMID: 35354072 Journal: European Journal of Pharmacology Year: 2022 Reference: Eur J Pharmacol. 2022 May 5;922:174905. doi: 10.1016/j.ejphar.2022.174905. Epub 2022 Mar 27. Impact factor: Publication type: Paper in international publication Authors: Araya, Erika Ivanna; Baggio, Darciane Favero; Chichorro, Juliana Geremias; Koren, Laura de Oliveira; Schwarting, Rainer K W et al. DOI: 10.1016/j.ejphar.2022.174905
PMID: 33778933 Journal: Pain and Therapy Year: 2021 Reference: Pain Ther. 2021 Jun;10(1):637-650. doi: 10.1007/s40122-021-00253-0. Epub 2021 Mar 28. Impact factor: Publication type: Paper in international publication Authors: Ahmed, Fayyaz; Alpuente, Alicia; Andreou, Anna P; Baraldi, Carlo; Brunelli, Nicoletta; Butera, Calogera; Cevoli, Sabina; Colombo, Bruno; Filatova, Elena; Filippi, Massimo et al. DOI: 10.1007/s40122-021-00253-0
PMID: 33772636 Journal: JOURNAL OF NEUROLOGY Year: 2021 Reference: J Neurol. 2021 Oct;268(10):3789-3798. doi: 10.1007/s00415-021-10523-8. Epub 2021 Mar 27. Impact factor: Publication type: Paper in international publication Authors: Alpuente, Alicia; Caronna, Edoardo; Gallardo, Victor J; Gine-Cipres, Eulalia; Pozo-Rosich, Patricia; Torres-Ferrus, Marta et al. DOI: 10.1007/s00415-021-10523-8
PMID: 33767185 Journal: Nature Reviews Disease Primers Year: 2021 Reference: Nat Rev Dis Primers. 2021 Mar 25;7(1):24. doi: 10.1038/s41572-021-00257-2. Impact factor: Publication type: Review in international publication Authors: Ashina, Hakan; Ashina, Sait; Buse, Dawn C; Diener, Hans-Christoph; Jensen, Rigmor H; Lee, Mi Ji; Lipton, Richard B; Messina, Roberta; Mitsikostas, Dimos D; Pozo-Rosich, Patricia et al. DOI: 10.1038/s41572-021-00257-2
PMID: 33766414 Journal: NEUROLOGIA Year: 2021 Reference: Neurologia (Engl Ed). 2021 Mar 22:S0213-4853(21)00036-0. doi: 10.1016/j.nrl.2021.02.006. Impact factor: Publication type: Paper in national publication Authors: Bohorquez, S; Camina, J; Diaz de Teran, J; Gago-Veiga, A; Gallardo, V J; Gonzalez-Garcia, N; Gonzalez-Quintanilla, V; Lopez-Veloso, A C; Mas-Sala, N; Pozo-Rosich, P et al. DOI: 10.1016/j.nrl.2021.02.006
PMID: 32421912 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2020 Reference: Eur J Neurol. 2020 Oct;27(10):2102-2108. doi: 10.1111/ene.14331. Epub 2020 Jun 17. Impact factor: 4.516 Publication type: Paper in international publication Authors: Alpuente, Alicia, Gallardo, Victor Jose, Torres-Ferrus, Marta, Santos-Lasaosa, Sonia, Guerrero, Angel, Lainez, Jose Miguel, Viguera, Javier, Gago-Veiga, Ana, Irimia, Pablo, Del Rio, Margarita Sanchez et al. DOI: 10.1111/ene.14331
PMID: 32349653 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2020 Reference: J Headache Pain. 2020 Apr 29;21(1):42. doi: 10.1186/s10194-020-01111-8. Impact factor: 4.797 Publication type: Review in international publication Authors: Lampl, C, van Hoogstraten, W S, Van den Abbeele, D, Torres-Ferrus, M, Ursitti, F, Alpuente-Ruiz, A, Brunello, F, Chiappino, D, de Vries, T, Di Marco, S et al. DOI: 10.1186/s10194-020-01111-8
PMID: 32086801 Journal: HEADACHE Year: 2020 Reference: Headache. 2020 Apr;60(4):677-685. doi: 10.1111/head.13765. Epub 2020 Feb 22. Impact factor: 4.041 Publication type: Paper in international publication Authors: Alpuente, Alicia, Gallardo, Victor Jose, Torres-Ferrus, Marta, Alvarez-Sabin, Jose, Pozo-Rosich, Patricia et al. DOI: 10.1111/head.13765
PMID: 32068897 Journal: HEADACHE Year: 2020 Reference: Headache. 2020 May;60(5):916-928. doi: 10.1111/head.13774. Epub 2020 Feb 18. Impact factor: 4.041 Publication type: Paper in international publication Authors: Fonseca, Elena, Caronna, Edoardo, Gallardo, Victor Jose, Torres-Ferrus, Marta, Pozo-Rosich, Patricia, Alpuente, Alicia, Gomez-Galvan, Juan Bernardo et al. DOI: 10.1111/head.13774
Two international studies led by Vall d'Hebron recommend early administration of specific drugs to prevent migraine to achieve a better response to therapy.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
The study, conducted in more than 770 people, concludes that atogepant reduces the frequency of migraine attacks and the need to take medication.
