Infectious Diseases
The VHIR Infectious Diseases research group is made up of medical professionals, with healthcare and clinical or basic translational research activities; of Biomedicine dedicated to basic research; and Nursing, with activities to support clinical research.
The group's lines of research are mainly focused on four areas:
Infections related to immunosuppression. Includes infectious diseases related to immunocompromised patients, solid organ or hematopoietic stem cell transplant recipients and recipients of biological therapies.
Sexually transmitted diseases, including HIV infection and other highly prevalent infections in our country (syphilis, gonorrhea, lymphogranuloma venere or infections caused by the human papillomavirus).
Infections related to health care, with special emphasis on those difficult to treat (cardiovascular infections or infections related to prosthetic materials) or caused by multi-resistant pathogens (MDRO) or affecting vulnerable populations.
Global Health and Tropical Diseases with special emphasis on prevalent diseases in our environment that affect the immigrant or displaced population.
Publications
Identification of HIV-reservoir cells with reduced susceptibility to antibody-dependent immune response.
PMID: 35616530
Journal: eLife
Year: 2022
Reference: Elife. 2022 May 26;11. pii: 78294. doi: 10.7554/eLife.78294.
Impact factor: 8.146
Publication type: Paper in international publication
Authors: Astorga-Gamaza, Antonio, Grau-Exposito, Judith, Burgos, Joaquin, Navarro, Jordi, Curran, Adria, Planas, Bibiana, Suanzes, Paula, Falco, Vicenc, Genesca, Meritxell, Buzon, Maria et al.
DOI: 10.7554/eLife.78294
Association of HLA-B*35 and moderate or severe cutaneous reactions secondary to benznidazole treatment in chronic Chagas disease patients.
PMID: 34863919
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2022
Reference: Clin Microbiol Infect. 2022 Jun;28(6):881.e1-881.e5. doi: 10.1016/j.cmi.2021.11.021. Epub 2021 Dec 1.
Impact factor: 8.067
Publication type: Paper in international publication
Authors: Bosch-Nicolau, P, Salvador, F, Sanchez-Montalva, A, Franco-Jarava, C, Arrese-Munoz, I, Sulleiro, E, Roure, S, Valerio, Ll, Oliveira-Souto, I, Serre-Delcor, N et al.
DOI: 10.1016/j.cmi.2021.11.021
Pharmacotherapeutic interventions for the treatment of bacterial prostatitis.
PMID: 35574695
Journal: EXPERT OPINION ON PHARMACOTHERAPY
Year: 2022
Reference: Expert Opin Pharmacother. 2022 Jun 27:1-11. doi: 10.1080/14656566.2022.2077101.
Impact factor: 3.889
Publication type: Review in international publication
Authors: Marquez-Algaba, Ester, Burgos, Joaquin, Almirante, Benito et al.
DOI: 10.1080/14656566.2022.2077101
Unified European support framework to sustain the HIV cascade of care for people living with HIV including in displaced populations of war-struck Ukraine.
PMID: 35576942
Journal: Lancet HIV
Year: 2022
Reference: Lancet HIV. 2022 Jun;9(6):e438-e448. doi: 10.1016/S2352-3018(22)00125-4. Epub 2022 May 13.
Impact factor: 12.767
Publication type: Review in international publication
Authors: Antoniak, Sergii, Gilles, Christine, Libois, Agnes, Curran, Adrian, Spinner, Christoph D, Rowley, Dominic, Bickel, Markus, Aichelburg, Maximilian C, Nozza, Silvia, Wensing, Annemarie et al.
DOI: 10.1016/S2352-3018(22)00125-4
COVID-19 Clinical Profile in Latin American Migrants Living in Spain: Does the Geographical Origin Matter?
PMID: 34830495
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Nov 9;10(22). pii: jcm10225213. doi: 10.3390/jcm10225213.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Sempere, Abiu, Salvador, Fernando, Monforte, Arnau, Sampol, Julia, Espinosa-Pereiro, Juan, Miarons, Marta, Bosch-Nicolau, Pau, Guillen-Del-Castillo, Alfredo, Aznar, Maria Luisa, Campos-Varela, Isabel et al.
DOI: 10.3390/jcm10225213
Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis.
PMID: 34819643
Journal: Nature Microbiology
Year: 2021
Reference: Nat Microbiol. 2021 Dec;6(12):1549-1560. doi: 10.1038/s41564-021-01000-z. Epub 2021 Nov 24.
Impact factor: 17.745
Publication type: Paper in international publication
Authors: Marks, Michael, Beale, Mathew A, Williamson, Deborah A, Hughes, Gwenda, Naidu, Prenilla, Unemo, Magnus, Krajden, Mel, Lukehart, Sheila A, Morshed, Muhammad G, Fifer, Helen et al.
DOI: 10.1038/s41564-021-01000-z
COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry.
PMID: 34777582
Journal: Therapeutic Advances in Medical Oncology
Year: 2021
Reference: Ther Adv Med Oncol. 2021 Nov 2;13:17588359211053416. doi: 10.1177/17588359211053416. eCollection 2021.
Impact factor: 8.168
Publication type: Paper in international publication
Authors: Pistilli, Barbara, Lambertini, Matteo, Ottaviani, Diego, Diamantis, Nikolaos, Lumsden, Ailsa, Pernas, Sonia, Generali, Daniele, Segui, Elia, Vinas, Gemma, Felip, Eudald et al.
DOI: 10.1177/17588359211053416
Changes in the microbiological diagnosis and epidemiology of cutaneous leishmaniasis in real-time PCR era: A six-year experience in a referral center in Barcelona.
PMID: 34758023
Journal: PLoS Neglected Tropical Diseases
Year: 2021
Reference: PLoS Negl Trop Dis. 2021 Nov 10;15(11):e0009884. doi: 10.1371/journal.pntd.0009884. eCollection 2021 Nov.
Impact factor: 4.411
Publication type: Paper in international publication
Authors: Silgado, Aroa, Armas, Mayuli, Sanchez-Montalva, Adrian, Goterris, Lidia, Ubals, Maria, Temprana-Salvador, Jordi, Aparicio, Gloria, Chicharro, Carmen, Serre-Delcor, Nuria, Ferrer, Berta et al.
DOI: 10.1371/journal.pntd.0009884
Deep-sequencing reveals broad subtype-specific HCV resistance mutations associated with treatment failure.
PMID: 31857134
Journal: ANTIVIRAL RESEARCH
Year: 2020
Reference: Antiviral Res. 2020 Feb;174:104694. doi: 10.1016/j.antiviral.2019.104694. Epub 2019 Dec 16.
Impact factor: 4.101
Publication type: Paper in international publication
Authors: Niubo, Jordi, Chen, Qian, Perales, Celia, Soria, Maria Eugenia, Garcia-Cehic, Damir, Gregori, Josep, Rodriguez-Frias, Francisco, Buti, Maria, Crespo, Javier, Calleja, Jose Luis et al.
DOI: 10.1016/j.antiviral.2019.104694
Preoperative oral antibiotics in colon surgery - Authors' reply.
PMID: 32818462
Journal: Lancet Gastroenterology & Hepatology
Year: 2020
Reference: Lancet Gastroenterol Hepatol. 2020 Sep;5(9):802-803. doi: 10.1016/S2468-1253(20)30241-7.
Impact factor: 14.789
Publication type: Letter or abstract
Authors: Almirante, Benito, Basany, Eloy Espin, Pellino, Gianluca et al.
DOI: 10.1016/S2468-1253(20)30241-7
Fixed vs adjusted-dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: A systematic review and meta-analysis.
PMID: 32804966
Journal: PLoS Neglected Tropical Diseases
Year: 2020
Reference: PLoS Negl Trop Dis. 2020 Aug 17;14(8):e0008529. doi: 10.1371/journal.pntd.0008529. eCollection 2020 Aug.
Impact factor: 3.885
Publication type: Paper in international publication
Authors: Ciapponi, Agustin, Barreira, Fabiana, Perelli, Lucas, Bardach, Ariel, Gascon, Joaquim, Molina, Israel, Morillo, Carlos, Prado, Nilda, Riarte, Adelina, Torrico, Faustino et al.
DOI: 10.1371/journal.pntd.0008529
Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients.
PMID: 32752979
Journal: Emerging Microbes & Infections
Year: 2020
Reference: Emerg Microbes Infect. 2020 Dec;9(1):1900-1911. doi: 10.1080/22221751.2020.1806735.
Impact factor: 5.776
Publication type: Paper in international publication
Authors: Almirante, Benito, Esteban, Juan Ignacio, Pumarola, Tomas, Anton, Andres, Quer, Josep, Ferrer, Ricard, Campins, Magda, Martin, Maria Carmen, Quer, Susanna, Andres, Cristina et al.
DOI: 10.1080/22221751.2020.1806735
Community-acquired respiratory viruses are a risk factor for chronic lung allograft dysfunction.
PMID: 30561555
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2019
Reference: Clin Infect Dis. 2019 Sep 13;69(7):1192-1197. doi: 10.1093/cid/ciy1047.
Impact factor: 9.055
Publication type: Paper in international publication
Authors: Ferrer, Ricard, Peghin, Maddalena, Los-Arcos, Ibai, Hirsch, Hans H, Codina, Gemma, Monforte, Victor, Bravo, Carles, Berastegui, Cristina, Jauregui, Alberto, Romero, Laura et al.
DOI: 10.1093/cid/ciy1047
Impact of de-escalation on prognosis of patients with bacteraemia due to Enterobacteriaceae: a post-hoc analysis from a multicenter prospective cohort.
PMID: 30535051
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2019
Reference: Clin Infect Dis. 2019 Aug 30;69(6):956-962. doi: 10.1093/cid/ciy1032.
Impact factor: 9.055
Publication type: Paper in international publication
Authors: Palacios-Baena, Zaira R, Almirante, Benito, Gomez-Zorrilla, Silvia, Borrell, Nuria, Corzo, Juan E, Gurgui, Mercedes, de la Calle, Cristina, Garcia-Alvarez, Lara, Ramos, Lucia, Gozalo, Monica et al.
DOI: 10.1093/cid/ciy1032
Enhanced molecular typing and macrolide and tetracycline-resistance mutations of Treponema pallidum in Barcelona.
PMID: 31512516
Journal: Future Microbiology
Year: 2019
Reference: Future Microbiol. 2019 Sep;14:1099-1108. doi: 10.2217/fmb-2019-0123.
Impact factor: 2.746
Publication type: Paper in international publication
Authors: Pumarola, Tomas, Vall-Mayans, Marti, Esperalba, Juliana, Sulleiro, Elena, Serra-Pladevall, Judit, Villatoro, Ana M, Fernandez-Naval, Candela, Arando, Maider, Espasa, Mateu, Anton, Andres et al.
DOI: 10.2217/fmb-2019-0123
Rapid subacute myelopathy following kidney transplantation from HTLV-1 donors: role of immunosuppresors and failure of antiretrovirals.
PMID: 31467675
Journal: Therapeutic advances in infectious disease
Year: 2019
Reference: Ther Adv Infect Dis. 2019 Aug 21;6:2049936119868028. doi: 10.1177/2049936119868028. eCollection 2019 Jan-Dec.
Impact factor: 0
Publication type: Paper in international publication
Authors: Rojo, S, Roc, Lourdes, de Mendoza, Carmen, Fernandez-Alonso, Miriam, Reina, Gabriel, Soriano, Vicente, Rodriguez, C, Vera, M, Del Romero, J, Marcaida, G et al.
DOI: 10.1177/2049936119868028
Prevalence of Chagas Disease among Solid Organ-Transplanted Patients in a Nonendemic Country.
PMID: 29405102
Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
Year: 2018
Reference: Am J Trop Med Hyg. 2018 Mar;98(3):742-746. doi: 10.4269/ajtmh.17-0735. Epub 2018 Feb 1.
Impact factor: 2.564
Publication type: Paper in international publication
Authors: Salvador, Fernando, Sanchez-Montalva, Adrian, Sulleiro, Elena, Moreso, Francesc, Berastegui, Cristina, Caralt, Mireia, Pinazo, Maria-Jesus, Moure, Zaira, Los-Arcos, Ibai, Len, Oscar et al.
DOI: 10.4269/ajtmh.17-0735
A pragmatic approach for mortality prediction after surgery in infective endocarditis: Optimizing and refining EuroSCORE.
PMID: 29408350
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2018
Reference: Clin Microbiol Infect. 2018 Oct;24(10):1102.e7-1102.e15. doi: 10.1016/j.cmi.2018.01.019. Epub 2018 Mar 3.
Impact factor: 5.394
Publication type: Paper in international publication
Authors: Aznar, Maria L, de Alarcon, Aristides, Garcia-Cabrera, Emilio, Galvez-Acebal, Juan, Sanchez-Espin, Gemma, Reguera-Iglesias, Jose M, De La Torre-Lima, Javier, Lomas, Jose M, Hidalgo-Tenorio, Carmen, Vallejo, Nuria et al.
DOI: 10.1016/j.cmi.2018.01.019
Ultrasound findings and associated factors to morbidity in Schistosoma haematobium infection in a highly endemic setting.
PMID: 29205689
Journal: TROPICAL MEDICINE & INTERNATIONAL HEALTH
Year: 2018
Reference: Trop Med Int Health. 2018 Feb;23(2):221-228. doi: 10.1111/tmi.13020. Epub 2017 Dec 20.
Impact factor: 2.541
Publication type: Paper in international publication
Authors: Garcia, Cristina Bocanegra, Pintar, Zeferino, Serres, Xavier, Mendioroz, Jacobo, Moreno, Milagros, Gallego, Sara, Lopez, Teresa, Soriano-Arandes, Antoni, Aznar, Maria Luisa, Sikaleta, Nicolau et al.
DOI: 10.1111/tmi.13020
Recommendations for Management of Endemic Diseases and Travel Medicine in Solid-Organ Transplant Recipients and Donors: Latin America - Map Gallery.
PMID: 29381582
Journal: TRANSPLANTATION
Year: 2018
Reference: Transplantation. 2018 Feb;102(2S Suppl 2):S81. doi: 10.1097/TP.0000000000002031.
Impact factor: 3.96
Publication type: Paper in international publication
Authors: Mourao, Paulo Henrique Orlandi, Gavalda, Joan, Salvador, Fernando, Molina, Israel et al.
DOI: 10.1097/TP.0000000000002031
The role of oncogenic HPV determination for diagnosis of high-grade anal intraepithelial neoplasia in HIV-infected MSM.
PMID: 28723712
Journal: AIDS
Year: 2017
Reference: AIDS. 2017 Oct 23;31(16):2227-2233. doi: 10.1097/QAD.0000000000001605.
Impact factor: 5.003
Publication type: Paper in international publication
Authors: Burgos, Joaquin, Hernandez-Losa, J, Landolfi, S, Guelar, A, Dinares, M femininec, Villar, J, Navarro, J, Ribera, E, Falco, V, Curran, A et al.
DOI: 10.1097/QAD.0000000000001605
A Novel Single-Cell FISH-Flow Assay Identifies Effector Memory CD4+ T cells as a Major Niche for HIV-1 Transcription in HIV-Infected Patients.
PMID: 28698276
Journal: mBio
Year: 2017
Reference: MBio. 2017 Jul 11;8(4). pii: e00876-17. doi: 10.1128/mBio.00876-17.
Impact factor: 6.956
Publication type: Paper in international publication
Authors: Buzon, Maria J, Crespo, Manuel, Falco, Vicenc, Grau-Exposito, Judith, Miguel, Lucia, Navarro, Jordi, Curran, Adria, Burgos, Joaquin, Ocana, Imma, Ribera, Esteban et al.
DOI: 10.1128/mBio.00876-17
Successful liver transplantation despite donor-transmitted ESBL-producing Klebsiella pneumoniae infection: Case report and review of the literature.
PMID: 28691772
Journal: Transplant Infectious Disease
Year: 2017
Reference: Transpl Infect Dis. 2017 Oct;19(5). doi: 10.1111/tid.12743. Epub 2017 Aug 2.
Impact factor: 1.719
Publication type: Review in international publication
Authors: Escola-Verge, Laura, Los-Arcos, Ibal, Gonzalez, Junajo, Lung, Mayli, Bilbao, Itxarone, Farre, Merce, Pont, Teresa, Sandiumenge, Alberto, Gavalda, Joan, Len, Oscar et al.
DOI: 10.1111/tid.12743
Epidemiological trends of HIV-1 infection in blood donors from Catalonia, Spain (2005-2014).
PMID: 28681400
Journal: TRANSFUSION
Year: 2017
Reference: Transfusion. 2017 Sep;57(9):2164-2173. doi: 10.1111/trf.14195. Epub 2017 Jul 5.
Impact factor: 3.386
Publication type: Paper in international publication
Authors: Bes, Marta, Piron, Maria, Casamitjana, Natalia, Gregori, Josep, Esteban, Juan Ignacio, Ribera, Esteban, Quer, Josep, Puig, Lluis, Sauleda, Silvia et al.
DOI: 10.1111/trf.14195
News
The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.
On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.
Vall d'Hebron has coordinated this initiative that has carried out numerous training and community awareness activities aimed at empowering young people in sexual and reproductive health issues.