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Microbiology

The Microbiology research group of the Vall d'Hebron Research Institute (VHIR) focuses on the study of microbiological aspects —in basic, translational and clinical research— that could improve the outcome of patients with infectious diseases.

Our priority research areas are:

  • Microbiological surveillance of emerging and re-emerging infectious diseases.
    • Diseases due to viral infections of the respiratory tract
    • Microorganisms that cause vaccine-preventable diseases
    • Infectious diseases of sexual transmission
  • Antimicrobial resistance
  • Sepsis
  • Development and validation of rapid microbiological diagnostic devices.
  • International Health
  • Hepatitis 

We actively collaborate with other microbiology laboratories, health services, national and international centres and organizations, as well as with the different research networks of the Carlos III Health Institute in Spain.

In addition, we carry out an important activity in the surveillance of the genotypic and phenotypic evolution of microorganisms present in the community in terms of their virulence, transmissibility, antigenic escape and antimicrobial resistance, in collaboration with public administrations, both at the national and international level.
 

Publications

Management of Hospitalized Respiratory Syncytial Virus Bronchiolitis in the Pediatric Ward in Spain: Assessing the Impact of a New Clinical Practice Protocol.

PMID: 34936054
Journal: PEDIATRIC DRUGS
Year: 2022
Reference: Paediatr Drugs. 2022 Jan;24(1):63-71. doi: 10.1007/s40272-021-00488-6. Epub 2021 Dec 22.
Impact factor:
Publication type: Paper in international publication
Authors: Andres, Cristina; Anton, Andres; Barcelo, Irene; Lera, Esther; Martinez, Laia; Peremiquel-Trillas, Paula; Rodrigo, Carlos; Rodrigo-Pendas, Jose Angel; Vila, Jorgina et al.
DOI: 10.1007/s40272-021-00488-6

Justification for 24/7 clinical microbiology services.

PMID: 34991847
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2022
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2022 Jan;40(1):1-4. doi: 10.1016/j.eimce.2021.08.014.
Impact factor:
Publication type: Editorail in international publication
Authors: Alvarez de Luna, Fran Franco; Angel Goenaga, Miguel; Bou, German; Calbo, Esther; Canton, Rafael; Carlos Rodriguez, Juan; Crespo, Manuel; Garcia Rodriguez, Julio; Gonzalez, Julia; Gonzalez-Garcia, Juan et al.
DOI: 10.1016/j.eimce.2021.08.014

A year living with SARS-CoV-2: an epidemiological overview of viral lineage circulation by whole-genome sequencing in Barcelona city (Catalonia, Spain).

PMID: 34842496
Journal: Emerging Microbes & Infections
Year: 2022
Reference: Emerg Microbes Infect. 2022 Dec;11(1):172-181. doi: 10.1080/22221751.2021.2011617.
Impact factor:
Publication type: Paper in international publication
Authors: Andres, Cristina; Anton, Andres; Blanco-Grau, Albert; Borras-Bermejo, Blanca; Campins-Marti, Magda; Campos, Carolina; Castillo, Carla; Codina, Maria Gema; Colomer-Castell, Sergi; Esperalba, Juliana et al.
DOI: 10.1080/22221751.2021.2011617

Mycotic aneurysm of Internal Carotid Artery Secondary to Livestock-associated Methicillin-resistant Staphylococcus Aureus Clonal Complex CC398.

PMID: 34481883
Journal: ANNALS OF VASCULAR SURGERY
Year: 2022
Reference: Ann Vasc Surg. 2022 Jan;78:379.e7-379.e10. doi: 10.1016/j.avsg.2021.06.031. Epub 2021 Sep 3.
Impact factor:
Publication type: Letter or abstract
Authors: Bellmunt-Montoya, Sergi; Escola-Verge, Laura; Gil-Sala, Daniel; Gonzalez-Lopez, Juan Jose; Lung, Mayli; Tenezaca-Sari, Xavier et al.
DOI: 10.1016/j.avsg.2021.06.031

Gestation and COVID-19: clinical and microbiological observational study (Gesta-COVID19).

PMID: 33482757
Journal: BMC Pregnancy and Childbirth
Year: 2021
Reference: BMC Pregnancy Childbirth. 2021 Jan 22;21(1):78. doi: 10.1186/s12884-021-03572-4.
Impact factor:
Publication type: Paper in international publication
Authors: Anton, Andres; Anton, Andres; Arevalo, Silvia; Barranco, Francisco Jose; Camba, Fatima; Camba, Fatima; Carbonell, Melchor; Carbonell, Melchor; Carreras, Elena; Carreras, Elena et al.
DOI: 10.1186/s12884-021-03572-4

Detection of Viruses and Virus-Neutralizing Antibodies Using Synthetic Erythrocytes: Toward a Tuneable Tool for Virus Surveillance.

PMID: 33427446
Journal: ACS Sensors
Year: 2021
Reference: ACS Sens. 2021 Jan 22;6(1):83-90. doi: 10.1021/acssensors.0c01830. Epub 2021 Jan 11.
Impact factor:
Publication type: Paper in international publication
Authors: Andres, Cristina; Anton, Andres; Baldrich, Eva; Herance, Jose R; Pumarola, Tomas; Sanchez-Cano, Ana et al.
DOI: 10.1021/acssensors.0c01830

[Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units].

PMID: 32998844
Journal: ANALES DE PEDIATRIA
Year: 2021
Reference: An Pediatr (Barc). 2021 Jan;94(1):19-27. doi: 10.1016/j.anpedi.2020.03.013. Epub 2020 Sep 29.
Impact factor:
Publication type: Paper in national publication
Authors: Campins, Magda; Ciruela, Pilar; Codina, Gemma; de Sevilla, Mariona Fernandez; Diaz-Conradi, Alvaro; Dominguez, Angela; Dominguez, Angela; Esteva, Cristina; Fernandez de Sevilla, Mariona; Garcia-Garcia, Juan Jose et al.
DOI: 10.1016/j.anpedi.2020.03.013

Secular trends in the epidemiology and clinical characteristics of Enterococcus faecalis infective endocarditis at a referral center (2007-2018).

PMID: 33404892
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2021
Reference: Eur J Clin Microbiol Infect Dis. 2021 Jun;40(6):1137-1148. doi: 10.1007/s10096-020-04117-x. Epub 2021 Jan 6.
Impact factor:
Publication type: Paper in international publication
Authors: Almirante, Benito; Escola-Verge, Laura; Fernandez-Galera, Ruben; Fernandez-Hidalgo, Nuria; Larrosa, Maria Nieves et al.
DOI: 10.1007/s10096-020-04117-x

Hantavirus Pulmonary Syndrome in Traveler Returning from Nepal to Spain.

PMID: 31674901
Journal: EMERGING INFECTIOUS DISEASES
Year: 2020
Reference: Emerg Infect Dis. 2020 Jan;26(1):150-153. doi: 10.3201/eid2601.181685. Epub 2020 Jan 17.
Impact factor:
Publication type: Paper in international publication
Authors: Aznar, Maria Luisa; de Ory, Fernando; Diaz-Lagares, Candido; Espasa, Mateu; Martinez, Miguel J; Molina, Daniel; Molina, Israel; Oliveira, Ines; Pumarola, Tomas; Salvador, Fernando et al.
DOI: 10.3201/eid2601.181685

Vancomycin-Gentamicin Prefabricated Spacers in 2-Stage Revision Arthroplasty for Chronic Hip and Knee Periprosthetic Joint Infection: Insights Into Reimplantation Microbiology and Outcomes.

PMID: 31530462
Journal: JOURNAL OF ARTHROPLASTY
Year: 2020
Reference: J Arthroplasty. 2020 Jan;35(1):247-254. doi: 10.1016/j.arth.2019.07.043. Epub 2019 Aug 19.
Impact factor:
Publication type: Paper in international publication
Authors: Corona, Pablo S; Corro, Sebastian; Lung, Mayli; Pigrau, Carles; Rodriguez-Pardo, Dolors; Vicente, Matias et al.
DOI: 10.1016/j.arth.2019.07.043

Survey of diagnostic resources for STI in Spain.

PMID: 32826099
Journal:
Year: 2020
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2020 Aug 18:S0213-005X(20)30255-X. doi: 10.1016/j.eimc.2020.06.018.
Impact factor:
Publication type: Paper in international publication
Authors: Del Romero-Guerrero, Jorge; Gil-Alonso, Leire; Lopez-de Munain, Josefina; Otero-Guerra, Luis; Serra-Pladevall, Judit; Vazquez, Fernando et al.
DOI: 10.1016/j.eimc.2020.06.018

Development of DNA Aptamers Against Plasmodium falciparum Blood Stages Using Cell-Systematic Evolution of Ligands by EXponential Enrichment.

PMID: 32493542
Journal: Journal of Biomedical Nanotechnology
Year: 2020
Reference: J Biomed Nanotechnol. 2020 Mar 1;16(3):315-334. doi: 10.1166/jbn.2020.2901.
Impact factor: 4.483
Publication type: Paper in international publication
Authors: Ramirez, Miriam, Lantero, Elena, Belavilas-Trovas, Alexandros, Biosca, Arnau, Recolons, Paula, Moles, Ernest, Sulleiro, Elena, Zarzuela, Francesc, Avalos-Padilla, Yunuen, Fernandez-Busquets, Xavier et al.
DOI: 10.1166/jbn.2020.2901

Prevalence and risk factors of multidrug-resistant tuberculosis in Cubal, Angola: a prospective cohort study.

PMID: 30674377
Journal: INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
Year: 2019
Reference: Int J Tuberc Lung Dis. 2019 Jan 1;23(1):67-72. doi: 10.5588/ijtld.18.0231.
Impact factor:
Publication type: Paper in international publication
Authors: Aznar, M L; Bocanegra, C; Eugenio, A Ninda; Fernandez, M T Tortola; Gabriel, E; Garcia, M T Lopez; Igual, E S; Katimba, D; Mendioroz, J; Moreno, M M et al.
DOI: 10.5588/ijtld.18.0231

Faecal phageome of healthy individuals: presence of antibiotic resistance genes and variations caused by ciprofloxacin treatment.

PMID: 30649322
Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Year: 2019
Reference: J Antimicrob Chemother. 2019 Apr 1;74(4):854-864. doi: 10.1093/jac/dky540.
Impact factor:
Publication type: Paper in international publication
Authors: Brown-Jaque, Maryury; Espinal, Paula; Fernandez-Orth, Dietmar; Gonzalez-Lopez, Juan Jose; Miro, Elisenda; Muniesa, Maite; Navarro, Ferran; Rodriguez-Navarro, Judith; Rodriguez-Rubio, Lorena et al.
DOI: 10.1093/jac/dky540

Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope(R).

PMID: 30628529
Journal: CRITICAL REVIEWS IN MICROBIOLOGY
Year: 2019
Reference: Crit Rev Microbiol. 2019 Feb;45(1):1-21. doi: 10.1080/1040841X.2018.1514366. Epub 2019 Jan 10.
Impact factor:
Publication type: Paper in international publication
Authors: Aurbach, Ute; Bachmann, Bjorn; Borchert, Kersten; Burchardt, Alexander; Caggiano, Giuseppina; Chakrabarti, Arunaloke; Chander, Jagdish; Chedotal, Isabelle; Cheng, Matthew P; Christopeit, Maximilian et al.
DOI: 10.1080/1040841X.2018.1514366

Knufia epidermidis: A rare finding in a paediatric dermatological sample.

PMID: 30114511
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2019
Reference: Clin Microbiol Infect. 2019 Jan;25(1):65-66. doi: 10.1016/j.cmi.2018.08.006. Epub 2018 Aug 13.
Impact factor:
Publication type: Paper in international publication
Authors: Cano-Lira, Jose F; Martin-Gomez, M Teresa; Valenzuela-Lopez, Nicomedes et al.
DOI: 10.1016/j.cmi.2018.08.006

Blog

News

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The new diagnostic method, designed for use in endemic regions, combines a mobile application with a low-cost robotic microscope.