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Microbiology

The Microbiology research group of the Vall d'Hebron Research Institute (VHIR) focuses on the study of microbiological aspects —in basic, translational and clinical research— that could improve the outcome of patients with infectious diseases.

Our priority research areas are:

  • Microbiological surveillance of emerging and re-emerging infectious diseases.
    • Diseases due to viral infections of the respiratory tract
    • Microorganisms that cause vaccine-preventable diseases
    • Infectious diseases of sexual transmission
  • Antimicrobial resistance
  • Sepsis
  • Development and validation of rapid microbiological diagnostic devices.
  • International Health
  • Hepatitis 

We actively collaborate with other microbiology laboratories, health services, national and international centres and organizations, as well as with the different research networks of the Carlos III Health Institute in Spain.

In addition, we carry out an important activity in the surveillance of the genotypic and phenotypic evolution of microorganisms present in the community in terms of their virulence, transmissibility, antigenic escape and antimicrobial resistance, in collaboration with public administrations, both at the national and international level.
 

Publications

COVID-19: an opportunity of systematic integration for Chagas disease. Example of a community-based approach within the Bolivian population in Barcelona.

PMID: 35346096
Journal: BMC INFECTIOUS DISEASES
Year: 2022
Reference: BMC Infect Dis. 2022 Mar 28;22(1):298. doi: 10.1186/s12879-022-07305-6.
Impact factor: 3.09
Publication type: Paper in international publication
Authors: Gomez I Prat, Jordi, Essadek, Hakima Ouaarab, Esperalba, Juliana, Serrat, Francesc Zarzuela, Guiu, Isabel Claveria, Goterris, Lidia, Zules-Ona, Ricardo, Choque, Estefa, Pastoret, Conxita, Ponces, Natalia Casamitjana et al.
DOI: 10.1186/s12879-022-07305-6

Next-Generation Sequencing for Confronting Virus Pandemics.

PMID: 35337007
Journal: Viruses-Basel
Year: 2022
Reference: Viruses. 2022 Mar 14;14(3). pii: v14030600. doi: 10.3390/v14030600.
Impact factor: 5.048
Publication type: Review in international publication
Authors: Anton, Andres, Quer, Josep, Colomer-Castell, Sergi, Campos, Carolina, Andres, Cristina, Pinana, Maria, Cortese, Maria Francesca, Gonzalez-Sanchez, Alejandra, Garcia-Cehic, Damir, Ibanez, Marta et al.
DOI: 10.3390/v14030600

Epidemiological and Genetic Characterization of Norovirus Outbreaks That Occurred in Catalonia, Spain, 2017-2019.

PMID: 35336893
Journal: Viruses-Basel
Year: 2022
Reference: Viruses. 2022 Feb 27;14(3). pii: v14030488. doi: 10.3390/v14030488.
Impact factor: 5.048
Publication type: Paper in international publication
Authors: Razquin, Efren, Cornejo Sanchez, Thais, Bartolome, Rosa, Torner, Nuria, Izquierdo, Conchita, Soldevila, Nuria, Coronas, Lorena, Dominguez, Angela, Fuentes, Cristina, Pinto, Rosa M et al.
DOI: 10.3390/v14030488

Inspecting the Ribozyme Region of Hepatitis Delta Virus Genotype 1: Conservation and Variability.

PMID: 35215809
Journal: Viruses-Basel
Year: 2022
Reference: Viruses. 2022 Jan 22;14(2). pii: v14020215. doi: 10.3390/v14020215.
Impact factor: 5.048
Publication type: Paper in international publication
Authors: Rodriguez-Frias, Francisco, Pacin-Ruiz, Beatriz, Cortese, Maria Francesca, Tabernero, David, Sopena, Sara, Gregori, Josep, Garcia-Garcia, Selene, Najarro, Adrian, Aldama, Unai, Palom, Adriana et al.
DOI: 10.3390/v14020215

Evaluation of the performance of Loopamp Trypanosoma cruzi Detection Kit for the diagnosis of Chagas disease in a non-endemic area, Spain.

PMID: 33692137
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2021
Reference: J Clin Microbiol. 2021 Apr 20;59(5). pii: JCM.01860-20. doi: 10.1128/JCM.01860-20. Print 2021 Apr 20.
Impact factor: 5.948
Publication type: Paper in international publication
Authors: Flores-Chavez, Maria D, Abras, Alba, Ballart, Cristina, Ibanez Perez, Ismael, Perez-Gordillo, Pilar, Gallego, Montserrat, Moure, Zaira, Sulleiro Igual, Elena, Nieto, Javier, Garcia Diez, Emilia et al.
DOI: 10.1128/JCM.01860-20

Emergence and dissemination of three mild outbreaks of Neisseria gonorrhoeae with high-level resistance to azithromycin in Barcelona, 2016-18.

PMID: 33367806
Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Year: 2021
Reference: J Antimicrob Chemother. 2021 Mar 12;76(4):930-935. doi: 10.1093/jac/dkaa536.
Impact factor: 5.79
Publication type: Paper in international publication
Authors: Pumarola, T, Hoyos-Mallecot, Y, Serra-Pladevall, J, Gonzalez-Lopez, J J, Arando, M, Barbera, M J, Cornejo-Sanchez, T, Salmeron, P, Moreno-Mingorance, A, Trejo, J et al.
DOI: 10.1093/jac/dkaa536

Prescription quality of prolonged antibiotherapy in pediatrics. Impact of ASP program interventions.

PMID: 32229130
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2021
Reference: Enferm Infecc Microbiol Clin. 2021 Mar;39(3):134-138. doi: 10.1016/j.eimc.2020.02.015. Epub 2020 Mar 27.
Impact factor: 1.731
Publication type: Paper in national publication
Authors: Melendo, Susana, Fernandez-Polo, Aurora, Castellnou Asens, Ivette, Mendoza-Palomar, Natalia, Barnes-Mayolas, Meritxell, Soler-Palacin, Pere, Soler Palacin, Pere, Melendo Perez, Susana, Mendoza Palomar, Natalia, Nieves Larrosa Escartin, M et al.
DOI: 10.1016/j.eimc.2020.02.015

Detection of Plasmodium falciparum malaria in 1 h using a simplified enzyme-linked immunosorbent assay.

PMID: 33648654
Journal: ANALYTICA CHIMICA ACTA
Year: 2021
Reference: Anal Chim Acta. 2021 Apr 1;1152:338254. doi: 10.1016/j.aca.2021.338254. Epub 2021 Jan 30.
Impact factor: 6.558
Publication type: Paper in international publication
Authors: de la Serna, Erica, Arias-Alpizar, Kevin, Borgheti-Cardoso, Livia Neves, Sanchez-Cano, Ana, Sulleiro, Elena, Zarzuela, Francesc, Bosch-Nicolau, Pau, Salvador, Fernando, Molina, Israel, Ramirez, Miriam et al.
DOI: 10.1016/j.aca.2021.338254

Diagnostic Accuracy of QuantiFERON-TB Gold Plus Assays in Children and Adolescents with Tuberculosis Disease.

PMID: 32334890
Journal: JOURNAL OF PEDIATRICS
Year: 2020
Reference: J Pediatr. 2020 Aug;223:212-215.e1. doi: 10.1016/j.jpeds.2020.02.025. Epub 2020 Apr 22.
Impact factor: 3.7
Publication type: Letter or abstract
Authors: Peromingo, Estrella, Santiago, Begona, Monsonis, Manuel, Calvo, Cristina, Cobo, Elvira, Colino, Elena, Espiau, Maria, Guerrero-Laleona, Carmelo, Lobato, Zulema, Martin-Nalda, Andrea et al.
DOI: 10.1016/j.jpeds.2020.02.025

Efficacy and safety assessment of different dosage of benznidazol for the treatment of Chagas disease in chronic phase in adults (MULTIBENZ study): study protocol for a multicenter randomized Phase II non-inferiority clinical trial.

PMID: 32293523
Journal: Trials
Year: 2020
Reference: Trials. 2020 Apr 15;21(1):328. doi: 10.1186/s13063-020-4226-2.
Impact factor: 1.883
Publication type: Paper in international publication
Authors: Molina-Morant, D, Fernandez, M L, Bosch-Nicolau, P, Sulleiro, E, Bangher, M, Salvador, F, Sanchez-Montalva, A, Ribeiro, A L P, de Paula, A M B, Eloi, S et al.
DOI: 10.1186/s13063-020-4226-2

Recommendations of the Spanish Antibiogram Committee (COESANT) for selecting antimicrobial agents and concentrations for in vitro susceptibility studies using automated systems.

PMID: 30878313
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2020
Reference: Enferm Infecc Microbiol Clin. 2020 Apr;38(4):182-187. doi: 10.1016/j.eimc.2019.01.017. Epub 2019 Mar 14.
Impact factor: 1.654
Publication type: Review in national publication
Authors: Oteo, Jesus, Pascual, Alvaro, Perez-Trallero, Emilio, Perez-Vazquez, Maria, Soriano, Alex, Torres, Carmen, Vila, Jordi, Martinez-Martinez, Luis, Navarro, Ferran, Morosini, Maria Isabel et al.
DOI: 10.1016/j.eimc.2019.01.017

Routine Bile Culture From Liver Donors as Screening of Donor-Transmitted Infections in Liver Transplantation.

PMID: 32289870
Journal: LIVER TRANSPLANTATION
Year: 2020
Reference: Liver Transpl. 2020 Sep;26(9):1121-1126. doi: 10.1002/lt.25778. Epub 2020 Aug 4.
Impact factor: 4.57
Publication type: Paper in international publication
Authors: Perez-Cameo, Cristina, Bilbao, Itxarone, Lung, Mayli, Caralt, Mireia, Vargas, Victor, Pont, Teresa, Nuvials, Xavier, Los-Arcos, Ibai, Castells, Lluis, Len, Oscar et al.
DOI: 10.1002/lt.25778

The challenge of the laboratory diagnosis in a confirmed congenital Zika virus syndrome in utero: A case report.

PMID: 31096455
Journal: MEDICINE
Year: 2019
Reference: Medicine (Baltimore). 2019 May;98(20):e15532. doi: 10.1097/MD.0000000000015532.
Impact factor: 1.87
Publication type: Paper in international publication
Authors: Pumarola, Tomas, Soler-Palacin, Pere, Soriano-Arandes, Antoni, Martinon-Torres, Federico, Alarcon, Ana, Melendo, Susana, Sulleiro, Elena, Frick, Marie Antoinette, Rodo, Carlota, Espasa, Mateu et al.
DOI: 10.1097/MD.0000000000015532

Imported strongyloidiasis: Data from 1245 cases registered in the +REDIVI Spanish Collaborative Network (2009-2017).

PMID: 31095570
Journal: PLoS Neglected Tropical Diseases
Year: 2019
Reference: PLoS Negl Trop Dis. 2019 May 16;13(5):e0007399. doi: 10.1371/journal.pntd.0007399. eCollection 2019 May.
Impact factor: 4.487
Publication type: Paper in international publication
Authors: Salvador, Fernando, Trevino, Begona, Chamorro-Tojeiro, Sandra, Sanchez-Montalva, Adrian, Herrero-Martinez, Juan Maria, Rodriguez-Guardado, Azucena, Serre-Delcor, Nuria, Torrus, Diego, Goikoetxea, Josune, Zubero, Zurine et al.
DOI: 10.1371/journal.pntd.0007399

Retrospective Study of Cystic Echinococcosis in a Recent Cohort of a Referral Center for Liver Surgery.

PMID: 30242646
Journal: JOURNAL OF GASTROINTESTINAL SURGERY
Year: 2019
Reference: J Gastrointest Surg. 2019 Jun;23(6):1148-1156. doi: 10.1007/s11605-018-3971-y. Epub 2018 Sep 21.
Impact factor: 2.686
Publication type: Paper in international publication
Authors: Escola-Verge, Laura, Salvador, Fernando, Escudero-Fernandez, Jose Miguel, Sanchez-Montalva, Adrian, Sulleiro, Elena, Rando, Ariadna, Bilbao, Itxarone, Lazaro, Jose Luis, Serres, Xavier, Salvador, Josep et al.
DOI: 10.1007/s11605-018-3971-y

Recombinant CV-A6 strains related to hand-foot-mouth disease and herpangina at primary care centers (Barcelona, Spain).

PMID: 31033351
Journal: Future Microbiology
Year: 2019
Reference: Future Microbiol. 2019 Apr;14:499-507. doi: 10.2217/fmb-2018-0336. Epub 2019 Apr 29.
Impact factor: 2.746
Publication type: Paper in international publication
Authors: Fuentes, Francisco, Rubio, Susana, Pumarola, Tomas, Anton, Andres, Martin, Maria Carmen, Rodrigo, Carlos, Esperalba, Juliana, Andres, Cristina, Guasch, Eulalia, Pinana, Maria et al.
DOI: 10.2217/fmb-2018-0336

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