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Microbiology

The Microbiology research group of the Vall d'Hebron Research Institute (VHIR) focuses on the study of microbiological aspects —in basic, translational and clinical research— that could improve the outcome of patients with infectious diseases.

Our priority research areas are:

  • Microbiological surveillance of emerging and re-emerging infectious diseases.
    • Diseases due to viral infections of the respiratory tract
    • Microorganisms that cause vaccine-preventable diseases
    • Infectious diseases of sexual transmission
  • Antimicrobial resistance
  • Sepsis
  • Development and validation of rapid microbiological diagnostic devices.
  • International Health
  • Hepatitis 

We actively collaborate with other microbiology laboratories, health services, national and international centres and organizations, as well as with the different research networks of the Carlos III Health Institute in Spain.

In addition, we carry out an important activity in the surveillance of the genotypic and phenotypic evolution of microorganisms present in the community in terms of their virulence, transmissibility, antigenic escape and antimicrobial resistance, in collaboration with public administrations, both at the national and international level.
 

Publications

Precision medicine in sepsis and septic shock: From omics to clinical tools.

PMID: 35433311
Journal: World journal of critical care medicine
Year: 2022
Reference: World J Crit Care Med. 2022 Jan 9;11(1):1-21. doi: 10.5492/wjccm.v11.i1.1. eCollection 2022 Jan 9.
Impact factor: 0
Publication type: Review in international publication
Authors: Ruiz-Rodriguez, Juan Carlos, Ruiz-Sanmartin, Adolfo, Perez-Carrasco, Marcos, Palmada, Clara, Ribas, Vicent, Martinez-Gallo, Monica, Hernandez-Gonzalez, Manuel, Gonzalez-Lopez, Juan J, Larrosa, Nieves, Ferrer, Ricard et al.
DOI: 10.5492/wjccm.v11.i1.1

Drassanes Expres: a public and confidential testing service for asymptomatic STIs with same-day result notification.

PMID: 33846278
Journal: SEXUALLY TRANSMITTED INFECTIONS
Year: 2022
Reference: Sex Transm Infect. 2022 May;98(3):166-172. doi: 10.1136/sextrans-2020-054779. Epub 2021 Apr 12.
Impact factor: 3.519
Publication type: Paper in international publication
Authors: Pumarola, Tomas, Espasa, Mateu, Almirante, Benito, LLinas, Montserrat, Serra-Pladevall, Judit, Barbera, Maria Jesus, Garcia, Jorge Nestor, Sulleiro, Elena, Esperalba, Juliana, Salmeron, Paula et al.
DOI: 10.1136/sextrans-2020-054779

Standardized Hepatitis B Virus RNA Quantification in Untreated and Treated Chronic Patients: a Promising Marker of Infection Follow-Up.

PMID: 35377229
Journal: Microbiology Spectrum
Year: 2022
Reference: Microbiol Spectr. 2022 Apr 27;10(2):e0214921. doi: 10.1128/spectrum.02149-21. Epub 2022 Apr 4.
Impact factor: 7.171
Publication type: Paper in international publication
Authors: Rodriguez-Frias, Francisco, Buti, Maria, Pumarola, Tomas, Garcia-Garcia, Selene, Cortese, Maria Francesca, Riveiro-Barciela, Mar, Tabernero, David, Rodriguez-Algarra, Francisco, Palom, Adriana, Sopena, Sara et al.
DOI: 10.1128/spectrum.02149-21

Positive Polymerase Chain Reaction for SARS-CoV-2 in a Candidate Does Not Always Preclude Liver Transplantation: Case Report and Literature Review.

PMID: 35352636
Journal: Experimental and Clinical Transplantation
Year: 2022
Reference: Exp Clin Transplant. 2022 Mar;20(3):321-324. doi: 10.6002/ect.2021.0387.
Impact factor: 0.945
Publication type: Letter or abstract
Authors: Len, Oscar, Castells, Lluis, Nuvials, Xavier, Sellares-Nadal, Julia, Esperalba, Juliana, Marquez-Algaba, Ester, Los-Arcos, Ibai, Anton, Andres et al.
DOI: 10.6002/ect.2021.0387

Nasal high flow oxygen therapy in COVID-19 patients does not cause environmental surface contamination.

PMID: 34082060
Journal: JOURNAL OF HOSPITAL INFECTION
Year: 2021
Reference: J Hosp Infect. 2021 Oct;116:103-105. doi: 10.1016/j.jhin.2021.04.034. Epub 2021 May 31.
Impact factor: 3.926
Publication type: Letter or abstract
Authors: Armadans, Lluis, Segales, Joaquim, Pumarola, Tomas, Campins, Magda, Ferrer, Ricard, Rodriguez-Garrido, Virginia, Vergara-Alert, Julia, Anton, Andres, Rodon, Jordi, Pacheco, Andres et al.
DOI: 10.1016/j.jhin.2021.04.034

Peripheral and lung resident memory T cell responses against SARS-CoV-2.

PMID: 34021148
Journal: Nature Communications
Year: 2021
Reference: Nat Commun. 2021 May 21;12(1):3010. doi: 10.1038/s41467-021-23333-3.
Impact factor: 14.919
Publication type: Paper in international publication
Authors: Perea, David, Rosado, Joel, Falco, Anna, Kirkegaard, Cristina, Torrella, Ariadna, Planas, Bibiana, Navarro, Jordi, Suanzes, Paula, Alvarez-Sierra, Daniel, Ayora, Alfonso et al.
DOI: 10.1038/s41467-021-23333-3

Role of asymptomatic bacteriuria on early periprosthetic joint infection after hip hemiarthroplasty. BARIFER randomized clinical trial.

PMID: 33864153
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2021
Reference: Eur J Clin Microbiol Infect Dis. 2021 Nov;40(11):2411-2419. doi: 10.1007/s10096-021-04241-2. Epub 2021 Apr 16.
Impact factor: 3.267
Publication type: Paper in international publication
Authors: Rodriguez-Pardo, Dolors, Del Toro, Maria Dolores, Guio-Carrion, Laura, Escudero-Sanchez, Rosa, Fernandez-Sampedro, Marta, Garcia-Viejo, Miguel Angel, Velasco-Arribas, Maria, Soldevila-Boixader, Laura, Femenias, Magdalena, Iribarren, Jose Antonio et al.
DOI: 10.1007/s10096-021-04241-2

Infectious complications of non-surgical biliary tract manipulation in paediatric patients. Role of antibiotic prophylaxis.

PMID: 33715879
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2021
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2021 Mar 11. pii: S0213-005X(21)00045-8. doi: 10.1016/j.eimc.2021.01.019.
Impact factor: 1.731
Publication type: Paper in national publication
Authors: Soria-Navarro, Beatriz, Mendoza-Palomar, Natalia, Juamperez-Gomi, Javier, Melendo, Susana, Mercadal-Hally, Maria, Lung, Mayli, Perez, Maria Mercedes, Quintero, Jesus, Soler-Palacin, Pere et al.
DOI: 10.1016/j.eimc.2021.01.019

Effect of antiviral treatment in older patients hospitalized with confirmed influenza.

PMID: 32234540
Journal: ANTIVIRAL RESEARCH
Year: 2020
Reference: Antiviral Res. 2020 Jun;178:104785. doi: 10.1016/j.antiviral.2020.104785. Epub 2020 Mar 29.
Impact factor: 4.101
Publication type: Paper in international publication
Authors: Martin, Vicente, Egurrola, Mikel, Morales Suarez-Varela, Maria, Dominguez, Angela, Mayoral, J M, Diaz-Borrego, J, Morillo, A, Perez-Lozano, M J, Gutierrez, J, Perez-Ruiz, M et al.
DOI: 10.1016/j.antiviral.2020.104785

Hospital-acquired influenza infections detected by a surveillance system over six seasons, from 2010/2011 to 2015/2016.

PMID: 31992207
Journal: BMC INFECTIOUS DISEASES
Year: 2020
Reference: BMC Infect Dis. 2020 Jan 28;20(1):80. doi: 10.1186/s12879-020-4792-7.
Impact factor: 2.688
Publication type: Paper in international publication
Authors: Barrabeig, I, Godoy, P, Soldevila, N, Rius, C, Jane, M, Martinez, A, Cayla, J A, Dominguez, A, Alseda, M, Alvarez, J et al.
DOI: 10.1186/s12879-020-4792-7

mcr-Colistin Resistance Genes Mobilized by IncX4, IncHI2, and IncI2 Plasmids in Escherichia coli of Pigs and White Stork in Spain.

PMID: 32010114
Journal: Frontiers in Microbiology
Year: 2020
Reference: Front Microbiol. 2020 Jan 17;10:3072. doi: 10.3389/fmicb.2019.03072. eCollection 2019.
Impact factor: 4.235
Publication type: Paper in international publication
Authors: Migura-Garcia, Lourdes, Gonzalez-Lopez, Juan J, Martinez-Urtaza, Jaime, Aguirre Sanchez, J R, Moreno-Mingorance, A, Perez de Rozas, A, Hofle, Ursula, Gonzalez-Escalona, Narjol, Ramiro, Y et al.
DOI: 10.3389/fmicb.2019.03072

Two multi-fragment recombination events resulted in the beta-lactam-resistant serotype 11A-ST6521 related to Spain9V-ST156 pneumococcal clone spreading in south-western Europe, 2008 to 2016.

PMID: 32347199
Journal: Eurosurveillance
Year: 2020
Reference: Euro Surveill. 2020 Apr;25(16). doi: 10.2807/1560-7917.ES.2020.25.16.1900457.
Impact factor: 6.454
Publication type: Paper in international publication
Authors: Cercenado, Emilia, Larrosa, Nieves, Quesada, Maria Dolores, Fontanals, Dionisia, El-Mniai, Assiya, Cubero, Meritxell, Carrico, Joao A, Marti, Sara, Ramirez, Mario, Ardanuy, Carmen et al.
DOI: 10.2807/1560-7917.ES.2020.25.16.1900457

Invasive pneumococcal disease and influenza activity in pediatric population. Impact of PCV13 vaccination in pandemic and non-pandemic influenza periods.

PMID: 31189583
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2019
Reference: J Clin Microbiol. 2019 Jul 26;57(8). pii: JCM.00363-19. doi: 10.1128/JCM.00363-19. Print 2019 Aug.
Impact factor: 4.959
Publication type: Paper in international publication
Authors: Munoz-Almagro, Carmen, Ciruela, Pilar, Soldevila, Nuria, Izquierdo, Conchita, Codina, Maria Gemma, Diaz, Alvaro, Moraga-Llop, Fernando, Garcia-Garcia, Juan Jose, Dominguez, Angela, Hernandez, Sergi et al.
DOI: 10.1128/JCM.00363-19

Chronic Pulmonary Aspergillosis in a Tertiary Care Center in Spain: A Retrospective, Observational Study.

PMID: 31162731
Journal: MYCOSES
Year: 2019
Reference: Mycoses. 2019 Sep;62(9):765-772. doi: 10.1111/myc.12950. Epub 2019 Jun 25.
Impact factor: 3.065
Publication type: Paper in international publication
Authors: Ruiz-Camps, Isabel, Roldan, Elisa, Sampol, Julia, Martinez-Marti, Alex, Goterris-Bonet, Lidia, Martin, Maria Teresa, Aguilar-Company, Juan, Almirante, Benito et al.
DOI: 10.1111/myc.12950

Impact of antibiotic resistance on outcomes of neutropenic cancer patients with Pseudomonas aeruginosa bacteraemia (IRONIC study): study protocol of a retrospective multicentre international study.

PMID: 31129580
Journal: BMJ Open
Year: 2019
Reference: BMJ Open. 2019 May 24;9(5):e025744. doi: 10.1136/bmjopen-2018-025744.
Impact factor: 2.376
Publication type: Paper in international publication
Authors: Bassetti, Matteo, Albasanz-Puig, Adaia, Gudiol, Carlota, Parody, Rocio, Tebe, Cristian, Akova, Murat, Araos, Rafael, Bote, Anna, Brunel, Anne-Sophie, Calik, Sebnem et al.
DOI: 10.1136/bmjopen-2018-025744

A retrospective study on the influence of siblings' relatedness in Bolivian patients with chronic Chagas disease.

PMID: 31126327
Journal: Parasites & Vectors
Year: 2019
Reference: Parasit Vectors. 2019 May 24;12(1):260. doi: 10.1186/s13071-019-3518-4.
Impact factor: 3.031
Publication type: Paper in international publication
Authors: Espinosa-Pereiro, Juan, Sanchez-Montalva, Adrian, Salvador, Fernando, Sao-Aviles, Augusto, Sulleiro, Elena, Molina, Israel et al.
DOI: 10.1186/s13071-019-3518-4

Blog

News

The collaboration will focus on several key areas of mutual interest in microbiology in particular antimicrobial resistance and stewardship.

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

The new diagnostic method, designed for use in endemic regions, combines a mobile application with a low-cost robotic microscope.