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Microbiology

The Microbiology research group of the Vall d'Hebron Research Institute (VHIR) focuses on the study of microbiological aspects —in basic, translational and clinical research— that could improve the outcome of patients with infectious diseases.

Our priority research areas are:

  • Microbiological surveillance of emerging and re-emerging infectious diseases.
    • Diseases due to viral infections of the respiratory tract
    • Microorganisms that cause vaccine-preventable diseases
    • Infectious diseases of sexual transmission
  • Antimicrobial resistance
  • Sepsis
  • Development and validation of rapid microbiological diagnostic devices.
  • International Health
  • Hepatitis 

We actively collaborate with other microbiology laboratories, health services, national and international centres and organizations, as well as with the different research networks of the Carlos III Health Institute in Spain.

In addition, we carry out an important activity in the surveillance of the genotypic and phenotypic evolution of microorganisms present in the community in terms of their virulence, transmissibility, antigenic escape and antimicrobial resistance, in collaboration with public administrations, both at the national and international level.
 

Publications

Respiratory Syncytial Virus Infections in Young Children Presenting to Primary Care in Catalonia During the COVID-19 Pandemic.

PMID: 34922377
Journal: Journal of the Pediatric Infectious Diseases Socie
Year: 2022
Reference: J Pediatric Infect Dis Soc. 2022 Feb 23;11(2):69-72. doi: 10.1093/jpids/piab121.
Impact factor: 3.164
Publication type: Paper in international publication
Authors: Coma, Ermengol, Vila, Jorgina, Mendez-Boo, Leonardo, Anton, Andres, Mora, Nuria, Fina, Francesc, Fabregas, Mireia, Medina, Manuel et al.
DOI: 10.1093/jpids/piab121

Multicenter clinical evaluation of a novel transcription-mediated amplification assay for SARS-CoV-2 molecular testing.

PMID: 35185236
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2022
Reference: Enferm Infecc Microbiol Clin. 2022 Feb 14. pii: S0213-005X(22)00024-6. doi: 10.1016/j.eimc.2022.01.014.
Impact factor: 1.731
Publication type: Paper in national publication
Authors: Camara, Jordi, Anton, Andres, Fernandez-Huerta, Miguel, Salmeron, Paula, Hernandez-Hermida, Yolanda, Andres, Cristina, Niubo, Jordi, Calatayud, Laura, Angeles Dominguez, M, Pumarola, Tomas et al.
DOI: 10.1016/j.eimc.2022.01.014

Study protocol for monitoring SARS-CoV-2 infection and its determinants in Catalonia (Spain): an observational and participatory research approach in a Sentinel Network of Schools.

PMID: 35078847
Journal: BMJ Open
Year: 2022
Reference: BMJ Open. 2022 Jan 25;12(1):e055649. doi: 10.1136/bmjopen-2021-055649.
Impact factor: 2.692
Publication type: Paper in international publication
Authors: Blanco, Ignacio, Bordas, Anna, Soriano-Arandes, Antoni, Subirana, Maria, Malagrida, Rosina, Reyes-Uruena, Juliana Maria, Folch, Cinta, Soler-Palacin, Pere, Gascon, Mireia, Sunyer, Jordi et al.
DOI: 10.1136/bmjopen-2021-055649

Dynamics of SARS-CoV-2 Alpha (B.1.1.7) variant spread: The wastewater surveillance approach.

PMID: 35074352
Journal: ENVIRONMENTAL RESEARCH
Year: 2022
Reference: Environ Res. 2022 May 15;208:112720. doi: 10.1016/j.envres.2022.112720. Epub 2022 Jan 22.
Impact factor: 6.498
Publication type: Paper in international publication
Authors: Carcereny, Albert, Garcia-Pedemonte, David, Martinez-Velazquez, Adan, Quer, Josep, Garcia-Cehic, Damir, Gregori, Josep, Anton, Andres, Andres, Cristina, Pumarola, Tomas, Chacon-Villanueva, Carme et al.
DOI: 10.1016/j.envres.2022.112720

Does Routine Abdominal Drain Tip Culture Anticipate Post-Operative Infection in Liver Transplantation?

PMID: 32429799
Journal: Surgical Infections
Year: 2021
Reference: Surg Infect (Larchmt). 2021 Mar;22(2):222-226. doi: 10.1089/sur.2020.031. Epub 2020 May 20.
Impact factor: 2.15
Publication type: Paper in international publication
Authors: Perez-Cameo, Cristina, Lung, Mayli, Hidalgo, Ernesto, Gomez-Gavara, Concepcion, Vargas, Victor, Nuvials, Xavier, Los-Arcos, Ibai, Castells, Lluis, Len, Oscar et al.
DOI: 10.1089/sur.2020.031

Sophisticated viral quasispecies with a genotype-related pattern of mutations in the hepatitis B X gene of HBeAg-ve chronically infected patients.

PMID: 33603102
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Feb 18;11(1):4215. doi: 10.1038/s41598-021-83762-4.
Impact factor: 4.38
Publication type: Paper in international publication
Authors: Pacin Ruiz, Beatriz, Garcia-Garcia, Selene, Esteban-Mur, Rafael, Tabernero, David, Buti, Maria, Rodriguez-Frias, Francisco, Lopez-Martinez, Rosa, Rando, Ariadna, Quer, Josep, Yll, Marcal et al.
DOI: 10.1038/s41598-021-83762-4

Severe SARS-CoV-2 placenta infection can impact neonatal outcome in the absence of vertical transmission.

PMID: 33497369
Journal: JOURNAL OF CLINICAL INVESTIGATION
Year: 2021
Reference: J Clin Invest. 2021 Mar 15;131(6). pii: 145427. doi: 10.1172/JCI145427.
Impact factor: 14.808
Publication type: Paper in international publication
Authors: Nuciforo, Paolo, Cribiu, Fulvia Milena, Erra, Roberta, Pugni, Lorenza, Rubio-Perez, Carlota, Alonso, Lidia, Simonetti, Sara, Croci, Giorgio A, Serna, Garazi, Ronchi, Andrea et al.
DOI: 10.1172/JCI145427

Gestation and COVID-19: clinical and microbiological observational study (Gesta-COVID19).

PMID: 33482757
Journal: BMC Pregnancy and Childbirth
Year: 2021
Reference: BMC Pregnancy Childbirth. 2021 Jan 22;21(1):78. doi: 10.1186/s12884-021-03572-4.
Impact factor: 3.007
Publication type: Paper in international publication
Authors: Molina, Francisca Sonia, Sulleiro, Elena, Anton, Andres, Esperalba, Juliana, Fernandez-Hidalgo, Nuria, Frick, Marie Antoinette, Camba, Fatima, Pumarola, Tomas, Carreras, Elena, Mendoza, Manel et al.
DOI: 10.1186/s12884-021-03572-4

Parvovirus B19 Myocarditis: Looking Beyond the Heart.

PMID: 31335286
Journal: PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
Year: 2020
Reference: Pediatr Dev Pathol. 2020 Mar-Apr;23(2):158-162. doi: 10.1177/1093526619865641. Epub 2019 Jul 23.
Impact factor: 0.885
Publication type: Paper in international publication
Authors: Izquierdo-Blasco, Jaume, Salcedo Allende, Maria Teresa, Codina Grau, Maria Gemma, Gran, Ferran, Martinez Saez, Elena, Balcells, Joan et al.
DOI: 10.1177/1093526619865641

Mycoplasma genitalium macrolide resistance update: Rate among a 2016-2017 cohort of patients in Barcelona, Spain.

PMID: 31445815
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2020
Reference: Enferm Infecc Microbiol Clin. 2020 Mar;38(3):99-104. doi: 10.1016/j.eimc.2019.06.008. Epub 2019 Aug 21.
Impact factor: 1.654
Publication type: Paper in national publication
Authors: Fernandez-Huerta, Miguel, Vall, Marti, Fernandez-Naval, Candela, Barbera, Maria-Jesus, Arando, Maider, Lopez, Luis, Andreu, Antonia, Pumarola, Tomas, Serra-Pladevall, Judit, Esperalba, Juliana et al.
DOI: 10.1016/j.eimc.2019.06.008

Electrochemical POC device for fast malaria quantitative diagnosis in whole blood by using magnetic beads, Poly-HRP and microfluidic paper electrodes.

PMID: 31818756
Journal: BIOSENSORS & BIOELECTRONICS
Year: 2020
Reference: Biosens Bioelectron. 2020 Feb 15;150:111925. doi: 10.1016/j.bios.2019.111925. Epub 2019 Nov 26.
Impact factor: 10.257
Publication type: Paper in international publication
Authors: Molina, Israel, Ruiz-Vega, Gisela, Arias-Alpizar, Kevin, de la Serna, Erica, Borgheti-Cardoso, Livia Neves, Sulleiro, Elena, Del Campo, F Javier, Baldrich, Eva, Sanchez-Montalva, Adrian, Fernandez-Busquets, Xavier et al.
DOI: 10.1016/j.bios.2019.111925

Schistosomiasis in children: review of 51 imported cases in Spain.

PMID: 31821494
Journal: JOURNAL OF TRAVEL MEDICINE
Year: 2020
Reference: J Travel Med. 2020 Feb 3;27(1). pii: 5671715. doi: 10.1093/jtm/taz099.
Impact factor: 7.089
Publication type: Paper in international publication
Authors: Mendoza-Palomar, Natalia, Sulleiro, Elena, Perez-Garcia, Irene, Espiau, Maria, Soriano-Arandes, Antoni, Martin-Nalda, Andrea, Espasa, Mateu, Zarzuela, Francesc, Soler-Palacin, Pere et al.
DOI: 10.1093/jtm/taz099

Characterization of hepatitis B virus X gene quasispecies complexity in mono-infection and hepatitis delta virus superinfection.

PMID: 30983817
Journal: WORLD JOURNAL OF GASTROENTEROLOGY
Year: 2019
Reference: World J Gastroenterol. 2019 Apr 7;25(13):1566-1579. doi: 10.3748/wjg.v25.i13.1566.
Impact factor: 3.411
Publication type: Paper in international publication
Authors: Godoy, Cristina, Tabernero, David, Sopena, Sara, Gregori, Josep, Cortese, Maria Francesca, Gonzalez, Carolina, Casillas, Rosario, Yll, Marcal, Rando, Ariadna, Lopez-Martinez, Rosa et al.
DOI: 10.3748/wjg.v25.i13.1566

Novel tp0548 sequence-type of Treponema pallidum identified in Barcelona, Spain.

PMID: 30461599
Journal: SEXUALLY TRANSMITTED DISEASES
Year: 2019
Reference: Sex Transm Dis. 2019 May;46(5):e50-e52. doi: 10.1097/OLQ.0000000000000947.
Impact factor: 2.27
Publication type: Paper in international publication
Authors: Arando, Maider, Espasa, Mateu, Anton, Andres, Gimferrer, Laura, Pinana, Maria, Fernandez-Huerta, Miguel, Gonzalez-Lopez, Juan Jose, Serra-Pladevall, Judit, Pumarola, Tomas, Vall-Mayans, Marti et al.
DOI: 10.1097/OLQ.0000000000000947

Epidemiology and diagnosis of pleural tuberculosis in a low incidence country with high rate of immigrant population: A retrospective study.

PMID: 30449728
Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Year: 2019
Reference: Int J Infect Dis. 2019 Jan;78:34-38. doi: 10.1016/j.ijid.2018.10.005. Epub 2018 Oct 25.
Impact factor: 3.538
Publication type: Paper in international publication
Authors: Macias, Antonio, Sanchez-Montalva, Adrian, Salvador, Fernando, Villar, Ana, Tortola, Teresa, Saborit, Nuria, Molina, Israel et al.
DOI: 10.1016/j.ijid.2018.10.005

Plasmodium malariae in a Spanish traveller returning from Colombia.

PMID: 30924870
Journal: JOURNAL OF TRAVEL MEDICINE
Year: 2019
Reference: J Travel Med. 2019 Jun 1;26(4). pii: 5423127. doi: 10.1093/jtm/taz022.
Impact factor: 4.155
Publication type: Paper in international publication
Authors: Oliveira, I, Aznar, M L, Zarzuela, F, Sulleiro, E, Trevino, B, Serre, N, Pou, D, Salvador, F, Sanchez-Montalva, A, Bosch-Nicolau, P et al.
DOI: 10.1093/jtm/taz022

Blog

News

The collaboration will focus on several key areas of mutual interest in microbiology in particular antimicrobial resistance and stewardship.

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

The new diagnostic method, designed for use in endemic regions, combines a mobile application with a low-cost robotic microscope.