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Microbiology

The Microbiology research group of the Vall d'Hebron Research Institute (VHIR) focuses on the study of microbiological aspects —in basic, translational and clinical research— that could improve the outcome of patients with infectious diseases.

Our priority research areas are:

  • Microbiological surveillance of emerging and re-emerging infectious diseases.
    • Diseases due to viral infections of the respiratory tract
    • Microorganisms that cause vaccine-preventable diseases
    • Infectious diseases of sexual transmission
  • Antimicrobial resistance
  • Sepsis
  • Development and validation of rapid microbiological diagnostic devices.
  • International Health
  • Hepatitis 

We actively collaborate with other microbiology laboratories, health services, national and international centres and organizations, as well as with the different research networks of the Carlos III Health Institute in Spain.

In addition, we carry out an important activity in the surveillance of the genotypic and phenotypic evolution of microorganisms present in the community in terms of their virulence, transmissibility, antigenic escape and antimicrobial resistance, in collaboration with public administrations, both at the national and international level.
 

Publications

Outbreaks of Gastroenteritis Due to Norovirus in Schools and Summer Camps in Catalonia, 2017-2019.

PMID: 35543555
Journal: Microbiology Spectrum
Year: 2022
Reference: Microbiol Spectr. 2022 Jun 29;10(3):e0011922. doi: 10.1128/spectrum.00119-22. Epub 2022 May 11.
Impact factor: 7.171
Publication type: Paper in international publication
Authors: Parron, Ignacio, Barrabeig, Irene, Soldevila, Nuria, Bartolome, Rosa, Guix, Susana, Rius, Cristina, Cornejo-Sanchez, Thais, Izquierdo, Conchita, Dominguez, Angela et al.
DOI: 10.1128/spectrum.00119-22

Shared risk factors for COVID-19 and preeclampsia in the first trimester: An observational study.

PMID: 35505629
Journal: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
Year: 2022
Reference: Acta Obstet Gynecol Scand. 2022 Jul;101(7):803-808. doi: 10.1111/aogs.14371. Epub 2022 May 3.
Impact factor: 3.636
Publication type: Paper in international publication
Authors: Serrano, Berta, Mendoza, Manel, Garcia-Aguilar, Paula, Bonacina, Erika, Garcia-Ruiz, Itziar, Garcia-Manau, Pablo, Gil, Judit, Armengol-Alsina, Mireia, Fernandez-Hidalgo, Nuria, Sulleiro, Elena et al.
DOI: 10.1111/aogs.14371

Case Report: X-Linked SASH3 Deficiency Presenting as a Common Variable Immunodeficiency.

PMID: 35464398
Journal: Frontiers in Immunology
Year: 2022
Reference: Front Immunol. 2022 Apr 8;13:881206. doi: 10.3389/fimmu.2022.881206. eCollection 2022.
Impact factor: 7.561
Publication type: Paper in international publication
Authors: Labrador-Horrillo, Moises, Franco-Jarava, Clara, Parra-Martinez, Alba, Antolin, Maria, Salgado-Perandres, Sandra, Aguilo-Cucurull, Aina, Martinez-Gallo, Monica, Colobran, Roger, Garcia-Prat, Marina et al.
DOI: 10.3389/fimmu.2022.881206

Pertactin-Deficient Bordetella pertussis with Unusual Mechanism of Pertactin Disruption, Spain, 1986-2018.

PMID: 35447067
Journal: EMERGING INFECTIOUS DISEASES
Year: 2022
Reference: Emerg Infect Dis. 2022 May;28(5):967-976. doi: 10.3201/eid2805.211958.
Impact factor: 6.883
Publication type: Paper in international publication
Authors: Mir-Cros, Alba, Moreno-Mingorance, Albert, Martin-Gomez, M Teresa, Abad, Raquel, Bloise, Ivan, Campins, Magda, Gonzalez-Praetorius, Alejandro, Gutierrez, M Nieves, Martin-Gonzalez, Hector, Munoz-Almagro, Carmen et al.
DOI: 10.3201/eid2805.211958

Low seroprevalence of SARS-CoV-2 antibodies in a liver transplant cohort.

PMID: 34121244
Journal: TRANSPLANT INTERNATIONAL
Year: 2021
Reference: Transpl Int. 2021 Oct;34(10):1908-1913. doi: 10.1111/tri.13946. Epub 2021 Jul 27.
Impact factor: 3.782
Publication type: Paper in international publication
Authors: Campos-Varela, Isabel, Len, Oscar, Villagrasa, Ares, Marquez-Algaba, Ester, Esperalba, Juliana, Dopazo, Cristina, Los-Arcos, Ibai, Anton, Andres, Castells, Lluis et al.
DOI: 10.1111/tri.13946

Enterovirus-A71 Rhombencephalitis Outbreak in Catalonia: Characteristics, Management and Outcome.

PMID: 34097655
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2021
Reference: Pediatr Infect Dis J. 2021 Jul 1;40(7):628-633. doi: 10.1097/INF.0000000000003114.
Impact factor: 2.129
Publication type: Paper in international publication
Authors: Anton, Andres, Castellarnau, Ester, Delgado, Ignacio, Vazquez, Elida, Gonzalez, Sebastia, Mayol, Lluis, Mendez, Maria, Sole, Eduard, Rosal, Jaume, Andres, Cristina et al.
DOI: 10.1097/INF.0000000000003114

Intra-Discrete Typing Unit TcV Genetic Variability of Trypanosoma cruzi in Chronic Chagas' Disease Bolivian Immigrant Patients in Barcelona, Spain.

PMID: 34095255
Journal: Frontiers in Cardiovascular Medicine
Year: 2021
Reference: Front Cardiovasc Med. 2021 May 20;8:665624. doi: 10.3389/fcvm.2021.665624. eCollection 2021.
Impact factor: 6.05
Publication type: Paper in international publication
Authors: de Oliveira, Maykon Tavares, Sulleiro, Elena, da Silva, Maria Claudia, Silgado, Aroa, de Lana, Marta, da Silva, Joao Santana, Molina, Israel, Marin-Neto, J Antonio et al.
DOI: 10.3389/fcvm.2021.665624

Nasal high flow oxygen therapy in COVID-19 patients does not cause environmental surface contamination.

PMID: 34082060
Journal: JOURNAL OF HOSPITAL INFECTION
Year: 2021
Reference: J Hosp Infect. 2021 Oct;116:103-105. doi: 10.1016/j.jhin.2021.04.034. Epub 2021 May 31.
Impact factor: 3.926
Publication type: Letter or abstract
Authors: Armadans, Lluis, Segales, Joaquim, Pumarola, Tomas, Campins, Magda, Ferrer, Ricard, Rodriguez-Garrido, Virginia, Vergara-Alert, Julia, Anton, Andres, Rodon, Jordi, Pacheco, Andres et al.
DOI: 10.1016/j.jhin.2021.04.034

Clinical evaluation of the ResistancePlus MG FleXible test on the GeneXpert Infinity-48s instrument: a near-patient assay for simultaneous detection of Mycoplasma genitalium and macrolide resistance.

PMID: 32451118
Journal: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Year: 2020
Reference: Diagn Microbiol Infect Dis. 2020 Aug;97(4):115062. doi: 10.1016/j.diagmicrobio.2020.115062. Epub 2020 Apr 17.
Impact factor: 2.499
Publication type: Paper in international publication
Authors: Tulsiani-Drud, Suhella, Barbera, Maria-Jesus, Hoyos-Mallecot, Yannick, Serra-Pladevall, Judit, Pumarola, Tomas, Espasa, Mateu, Silgado, Aroa, Salmeron, Paula, Fernandez-Huerta, Miguel et al.
DOI: 10.1016/j.diagmicrobio.2020.115062

Leishmania infantum asymptomatic infection in inflammatory bowel disease patients under anti-TNF therapy.

PMID: 32420499
Journal: Heliyon
Year: 2020
Reference: Heliyon. 2020 May 8;6(5):e03940. doi: 10.1016/j.heliyon.2020.e03940. eCollection 2020 May.
Impact factor: 0
Publication type: Paper in international publication
Authors: Guillen, M Carmen, Alcover, M Magdalena, Borruel, Natalia, Sulleiro, Elena, Salvador, Fernando, Berenguer, Diana, Herrera-de Guise, Claudia, Rodriguez, Veronica, Moure, Zaira, Sanchez-Montalva, Adrian et al.
DOI: 10.1016/j.heliyon.2020.e03940

Clinical Outcomes of a Zika Virus Mother-Child Pair Cohort in Spain.

PMID: 32392815
Journal: Pathogens
Year: 2020
Reference: Pathogens. 2020 May 7;9(5). pii: pathogens9050352. doi: 10.3390/pathogens9050352.
Impact factor: 3.018
Publication type: Paper in international publication
Authors: Soler-Palacin, Pere, Espiau, Maria, Salazar, Ainara, Guarch-Ibanez, Borja, Vazquez, Ana, Navarro-Moron, Juan, Ramos-Amador, Jose-Tomas, Martin-Nalda, Andrea, Duenas, Eva, Blazquez-Gamero, Daniel et al.
DOI: 10.3390/pathogens9050352

Necrotizing fasciitis in haematological patients: a different scenario.

PMID: 32399706
Journal: ANNALS OF HEMATOLOGY
Year: 2020
Reference: Ann Hematol. 2020 Aug;99(8):1741-1747. doi: 10.1007/s00277-020-04061-y. Epub 2020 May 12.
Impact factor: 2.904
Publication type: Paper in international publication
Authors: Albasanz-Puig, A, Rodriguez-Pardo, D, Pigrau, C, Lung, M, Roldan, E, Corona, P S, Almirante, B, Ruiz-Camps, I et al.
DOI: 10.1007/s00277-020-04061-y

Epidemiology of congenital Chagas disease 6 years after implementation of a public health surveillance system, Catalonia, 2010 to 2015.

PMID: 31266591
Journal: Eurosurveillance
Year: 2019
Reference: Euro Surveill. 2019 Jun;24(26). doi: 10.2807/1560-7917.ES.2019.24.26.19-00011.
Impact factor: 7.421
Publication type: Paper in international publication
Authors: Basile, Luca, Ciruela, Pilar, Requena-Mendez, Ana, Vidal, M feminine Jose, Dopico, Eva, Martin-Nalda, Andrea, Sulleiro, Elena, Gascon, Joaquim, Jane, Mireia, The Working Group Of Congenital Chagas Disease In et al.
DOI: 10.2807/1560-7917.ES.2019.24.26.19-00011

Novel Human Astroviruses: Prevalence and Association with Common Enteric Viruses in Undiagnosed Gastroenteritis Cases in Spain.

PMID: 31252663
Journal: Viruses-Basel
Year: 2019
Reference: Viruses. 2019 Jun 27;11(7). pii: v11070585. doi: 10.3390/v11070585.
Impact factor: 3.811
Publication type: Paper in international publication
Authors: Vu, Diem-Lan, Sabria, Aurora, Rodriguez Garrido, Virginia, Goterris, Lidia, Bosch, Albert, Pinto, Rosa Maria, Guix, Susana, Michl, Kristina, Aregall, Nuria et al.
DOI: 10.3390/v11070585

A Community-Based Intervention for the Detection of Chagas Disease in Barcelona, Spain.

PMID: 31222620
Journal: JOURNAL OF COMMUNITY HEALTH
Year: 2019
Reference: J Community Health. 2019 Aug;44(4):704-711. doi: 10.1007/s10900-019-00684-z.
Impact factor: 1.572
Publication type: Paper in international publication
Authors: Gomez I Prat, Jordi, Peremiquel-Trillas, Paula, Claveria Guiu, Isabel, Choque, Estefa, Oliveira Souto, Ines, Serre Delcor, Nuria, Sulleiro, Elena, Espasa, Mateu, Pastoret, Conxita, de Los Santos, Juan Jose et al.
DOI: 10.1007/s10900-019-00684-z

Understanding the relation between Zika virus infection during pregnancy and adverse fetal, infant and child outcomes: a protocol for a systematic review and individual participant data meta-analysis of longitudinal studies of pregnant women and their infants and children.

PMID: 31217315
Journal: BMJ Open
Year: 2019
Reference: BMJ Open. 2019 Jun 18;9(6):e026092. doi: 10.1136/bmjopen-2018-026092.
Impact factor: 2.376
Publication type: Paper in international publication
Authors: Lan, Zhiyi, Sousa, Patricia, Soriano-Arandes, Antoni, Soria-Segarra, Carmen, Sanchez Clemente, Nuria, Rosenberger, Kerstin Daniela, Reveiz, Ludovic, Prata-Barbosa, Arnaldo, Pomar, Leo, Pela Rosado, Luiza Emylce et al.
DOI: 10.1136/bmjopen-2018-026092

Blog

News

The collaboration will focus on several key areas of mutual interest in microbiology in particular antimicrobial resistance and stewardship.

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

The new diagnostic method, designed for use in endemic regions, combines a mobile application with a low-cost robotic microscope.