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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

Collapsing Glomerulonephritis in a Kidney Transplant Recipient after mRNA SARS-CoV-2 Vaccination.

PMID: 35806939
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Jun 24;11(13). pii: jcm11133651. doi: 10.3390/jcm11133651.
Impact factor: 4.242
Publication type: Letter or abstract
Authors: Gomez Preciado, Francisco; De Carvalho Ovalles, Rosa Alejandra; Codina, Sergi; Donadeu, Laura; Fava, Alexandre; Martinez Valenzuela, Laura; Sandoval, Diego; Fernandez-Cidon, Barbara; Bestard, Oriol; Alia-Ramos, Pedro et al.
DOI: 10.3390/jcm11133651

Tacrolimus CYP3A Single-Nucleotide Polymorphisms and Preformed T- and B-Cell Alloimmune Memory Improve Current Pretransplant Rejection-Risk Stratification in Kidney Transplantation.

PMID: 35833145
Journal: Frontiers in Immunology
Year: 2022
Reference: Front Immunol. 2022 Jun 27;13:869554. doi: 10.3389/fimmu.2022.869554. eCollection 2022.
Impact factor: 7.561
Publication type: Paper in international publication
Authors: Crespo, Elena, Vidal-Alabro, Anna, Jouve, Thomas, Fontova, Pere, Stein, Maik, Mocka, Sonila, Meneghini, Maria, Sefrin, Anett, Hruba, Petra, Goma, Montserrat et al.
DOI: 10.3389/fimmu.2022.869554

Mortality in elderly patients starting hemodialysis program.

PMID: 35817409
Journal: SEMINARS IN DIALYSIS
Year: 2022
Reference: Semin Dial. 2022 Jul 11. doi: 10.1111/sdi.13114.
Impact factor: 3.455
Publication type: Paper in international publication
Authors: Toapanta, Nestor, Comas, Jordi, Leon Roman, Juan, Ramos, Natalia, Azancot, Maria, Bestard, Oriol, Tort, Jaume, Soler, Maria Jose et al.
DOI: 10.1111/sdi.13114

Proposed Definitions of Antibody-Mediated Rejection for Use as a Clinical Trial Endpoint in Kidney Transplantation.

PMID: 35669973
Journal: TRANSPLANT INTERNATIONAL
Year: 2022
Reference: Transpl Int. 2022 May 20;35:10140. doi: 10.3389/ti.2022.10140. eCollection 2022.
Impact factor: 3.782
Publication type: Editorail in international publication
Authors: Roufosse, Candice, Becker, Jan Ulrich, Rabant, Marion, Seron, Daniel, Bellini, Maria Irene, Bohmig, Georg A, Budde, Klemens, Diekmann, Fritz, Glotz, Denis, Naesens, Maarten et al.
DOI: 10.3389/ti.2022.10140

SARS CoV-2 seropositivity in hemodialysis patients.

PMID: 34217504
Journal: NEFROLOGIA
Year: 2021
Reference: Nefrologia (Engl Ed). 2021 May 27. pii: S0211-6995(21)00105-3. doi: 10.1016/j.nefro.2021.04.004.
Impact factor: 2.033
Publication type: Letter or abstract
Authors: Toapanta, Nestor, Castaneda, Zaira, Zuniga, Jose, Leon-Roman, Juan, Ramos, Natalia, Azancot, Maria, Soler, Maria Jose et al.
DOI: 10.1016/j.nefro.2021.04.004

Systemic sclerosis and microscopic polyangiitis after systemic exposure to silicone.

PMID: 34221392
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2021 Mar 15;14(7):1848-1850. doi: 10.1093/ckj/sfab058. eCollection 2021 Jul.
Impact factor: 4.452
Publication type: Letter or abstract
Authors: Segarra Medrano, Alfons, Roig Carcel, Jordi, Estaran, Elena, Abo Rivera, Annabel, Carrera Munoz, Claudia, Gonzalez Rodriguez, Jorge et al.
DOI: 10.1093/ckj/sfab058

Acute interstitial nephritis associated with immune checkpoint inhibitors: a single-centre experience.

PMID: 34221369
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2020 Feb 10;14(5):1364-1370. doi: 10.1093/ckj/sfaa008. eCollection 2021 May.
Impact factor: 4.452
Publication type: Paper in international publication
Authors: Oleas, Diana, Bolufer, Monica, Agraz, Irene, Felip, Enriqueta, Munoz, Eva, Gabaldon, Alejandra, Bury, Roxana, Espinel, Eugenia, Seron, Daniel, Garcia-Carro, Clara et al.
DOI: 10.1093/ckj/sfaa008

How to Assess Diabetic Kidney Disease Progression? From Albuminuria to GFR.

PMID: 34198818
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Jun 5;10(11). pii: jcm10112505. doi: 10.3390/jcm10112505.
Impact factor: 4.242
Publication type: Review in international publication
Authors: Bermejo, Sheila, Garcia-Carro, Clara, Vergara, Ander, Sanchez de la Nieta, M Dolores, Agraz, Irene, Soler, Maria Jose, Sanchez-Fructuoso, Ana I, Azancot, Maria A et al.
DOI: 10.3390/jcm10112505

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.

The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.