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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

Alloimmune Risk Stratification for Kidney Transplant Rejection.

PMID: 35669972
Journal: TRANSPLANT INTERNATIONAL
Year: 2022
Reference: Transpl Int. 2022 May 20;35:10138. doi: 10.3389/ti.2022.10138. eCollection 2022.
Impact factor: 3.782
Publication type: Editorail in international publication
Authors: Oberbauer, Rainer, Pengel, Liset, Schneeberger, Stefan, Naesens, Maarten, Mamode, Nizam, Heemann, Uwe, Furian, Lucrezia, Couzi, Lionel, Claas, Frans, Budde, Klemens et al.
DOI: 10.3389/ti.2022.10138

Evolution of the Definition of Rejection in Kidney Transplantation and Its Use as an Endpoint in Clinical Trials.

PMID: 35669978
Journal: TRANSPLANT INTERNATIONAL
Year: 2022
Reference: Transpl Int. 2022 May 20;35:10141. doi: 10.3389/ti.2022.10141. eCollection 2022.
Impact factor: 3.782
Publication type: Editorail in international publication
Authors: Rabant, Marion, Roufosse, Candice, Naesens, Maarten, Seron, Daniel, Becker, Jan Ulrich et al.
DOI: 10.3389/ti.2022.10141

Proposed Definitions of T Cell-Mediated Rejection and Tubulointerstitial Inflammation as Clinical Trial Endpoints in Kidney Transplantation.

PMID: 35669975
Journal: TRANSPLANT INTERNATIONAL
Year: 2022
Reference: Transpl Int. 2022 May 20;35:10135. doi: 10.3389/ti.2022.10135. eCollection 2022.
Impact factor: 3.782
Publication type: Review in international publication
Authors: Bellini, Maria Irene, Seron, Daniel, Rabant, Marion, Becker, Jan Ulrich, Roufosse, Candice, Diekmann, Fritz, Glotz, Denis, Hilbrands, Luuk, Loupy, Alexandre, Oberbauer, Rainer et al.
DOI: 10.3389/ti.2022.10135

Welcome editorial by the new CKJ Editor-in-Chief: Facing the future of CKJ with enthusiasm!

PMID: 35664277
Journal: Clinical Kidney Journal
Year: 2022
Reference: Clin Kidney J. 2022 May 30;15(6):1029-1033. doi: 10.1093/ckj/sfac121. eCollection 2022 Jun.
Impact factor: 4.452
Publication type: Editorail in international publication
Authors: Soler, Maria Jose et al.
DOI: 10.1093/ckj/sfac121

Long-term Effects of COVID-19 in Solid Organ Transplantation Recipients.

PMID: 34174006
Journal: Transplant Infectious Disease
Year: 2021
Reference: Transpl Infect Dis. 2021 Aug;23(4):e13677. doi: 10.1111/tid.13677. Epub 2021 Jul 12.
Impact factor: 2.228
Publication type: Letter or abstract
Authors: Garcia-Garcia, Sonia, Los-Arcos, Ibai, Moreso, Francesc, Berastegui, Cristina, Castells, Lluis, Gorgas Torner, Maria Q, Miarons, Marta, Larrosa-Garcia, Maria et al.
DOI: 10.1111/tid.13677

A multi-center study on safety and efficacy of immune checkpoint inhibitors in cancer patients with kidney transplant.

PMID: 33359528
Journal: KIDNEY INTERNATIONAL
Year: 2021
Reference: Kidney Int. 2021 Jul;100(1):196-205. doi: 10.1016/j.kint.2020.12.015. Epub 2020 Dec 24.
Impact factor: 10.612
Publication type: Paper in international publication
Authors: Blosser, Christopher, Zuniga, Sandra Carias, Soler, Maria Jose, Moreso, Francesc, Mithani, Zain, Ortiz-Melo, David, Jaimes, Edgar A, Gutgarts, Victoria, Lum, Erik, Danovitch, Gabriel M et al.
DOI: 10.1016/j.kint.2020.12.015

Renin-Angiotensin System Blockers and the Risk of COVID-19-Related Mortality in Patients with Kidney Failure.

PMID: 34088718
Journal: Clinical Journal of the American Society of Nephrology
Year: 2021
Reference: Clin J Am Soc Nephrol. 2021 Jul;16(7):1061-1072. doi: 10.2215/CJN.18961220. Epub 2021 Jun 4.
Impact factor: 8.237
Publication type: Paper in international publication
Authors: Soler, Maria Jose, Noordzij, Marlies, Abramowicz, Daniel, de Arriba, Gabriel, Basile, Carlo, van Buren, Marjolijn, Covic, Adrian, Crespo, Marta, Duivenvoorden, Raphael, Massy, Ziad et al.
DOI: 10.2215/CJN.18961220

COVID-19 in CKD Patients: Lessons from 553 CKD Patients with Biopsy-Proven Kidney Disease.

PMID: 34098555
Journal: KIDNEY & BLOOD PRESSURE RESEARCH
Year: 2021
Reference: Kidney Blood Press Res. 2021;46(4):452-459. doi: 10.1159/000515714. Epub 2021 Jun 7.
Impact factor: 2.687
Publication type: Paper in international publication
Authors: Agraz, Irene, Roman, Juan Leon, Garcia-Carro, Clara, Gabaldon, Alejandra, Torres, Irina, Bury, Roxana, Baldallo, Cinthia, Seron, Daniel, Soler, Maria Jose, Vergara, Ander et al.
DOI: 10.1159/000515714

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.

The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.