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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

COVID-19 pandemic waves and mortality among patients on kidney replacement therapy.

PMID: 35757188
Journal: Kidney International Reports
Year: 2022
Reference: Kidney Int Rep. 2022 Jun 20. pii: S2468-0249(22)01451-6. doi: 10.1016/j.ekir.2022.06.007.
Impact factor: 4.164
Publication type: Paper in international publication
Authors: Gansevoort, Ron T; Hilbrands, Luuk B; Safak, Seda; Toapanta, Nestor; Reina, Carlos C; Noordzij, Marlies; Facundo, Carme; Mitra, Sandip; Midtvedt, Karsten; Malfait, Thomas et al.
DOI: 10.1016/j.ekir.2022.06.007

Ageing meets kidney disease.

PMID: 35768070
Journal: AGE AND AGEING
Year: 2022
Reference: Age Ageing. 2022 Jun 30. pii: 6609704. doi: 10.1093/ageing/afac157.
Impact factor: 10.668
Publication type: Paper in international publication
Authors: Fouque, Denis; Soler, Maria Jose; Mattace-Raso, Francesco; Ortiz, Alberto et al.
DOI: 10.1093/ageing/afac157

Ageing meets kidney disease.

PMID: 35768068
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2022
Reference: Nephrol Dial Transplant. 2022 Jun 30. pii: 6619640. doi: 10.1093/ndt/gfac199.
Impact factor: 5.992
Publication type: Paper in international publication
Authors: Fouque, Denis; Soler, Maria Jose; Mattace-Raso, Francesco; Ortiz, Alberto et al.
DOI: 10.1093/ndt/gfac199

Immunotherapy and the Spectrum of Kidney Disease: Should We Individualize the Treatment?

PMID: 35775000
Journal: Frontiers in Medicine
Year: 2022
Reference: Front Med (Lausanne). 2022 Jun 14;9:906565. doi: 10.3389/fmed.2022.906565. eCollection 2022.
Impact factor: 5.093
Publication type: Review in international publication
Authors: Riveiro-Barciela, Mar; Bolufer, Monica; Bermejo, Sheila; Soler, Maria Jose et al.
DOI: 10.3389/fmed.2022.906565

SARS CoV-2 vaccination in patients receiving kidney replacement therapies: where are we now with the protective immune response?

PMID: 34289072
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2021
Reference: Nephrol Dial Transplant. 2021 Sep 27;36(10):1950-1954. doi: 10.1093/ndt/gfab227.
Impact factor: 5.992
Publication type: Letter whit IF
Authors: Soler, Maria Jose, Toapanta, Nestor, Bestard, Oriol et al.
DOI: 10.1093/ndt/gfab227

Use and safety of remdesivir in kidney transplant recipients with COVID-19.

PMID: 34250317
Journal: Kidney International Reports
Year: 2021
Reference: Kidney Int Rep. 2021 Sep;6(9):2305-2315. doi: 10.1016/j.ekir.2021.06.023. Epub 2021 Jul 6.
Impact factor: 4.164
Publication type: Paper in international publication
Authors: Lopez, Veronica, Buxeda, Anna, Arias-Cabrales, Carlos, Perez-Saez, Maria Jose, Cacho, Judit, Pelegrin, Sheila Cabello, Melilli, Edoardo, Aladren, Maria Jose, Galeano, Cristina, Lorenzo, Inmaculada et al.
DOI: 10.1016/j.ekir.2021.06.023

[Malignant hypertension and pheochromocytoma: a case report].

PMID: 34238673
Journal: Hipertension y riesgo vascular
Year: 2021
Reference: Hipertens Riesgo Vasc. 2021 Oct-Dec;38(4):201-205. doi: 10.1016/j.hipert.2021.05.003. Epub 2021 Jul 6.
Impact factor: 0
Publication type: Letter or abstract
Authors: Bury, R, Leon Roman, J, Casteras, A, Vergara, A, Biagetti, B, Garcia-Carro, C, Cordero-Vazquez, E, Hernandez Hernandez, I, Agraz, I, Soler, M J et al.
DOI: 10.1016/j.hipert.2021.05.003

COVID-19 in Solid Organ Transplant Recipients in Spain Throughout 2020: Catching the Wave?

PMID: 34241988
Journal: TRANSPLANTATION
Year: 2021
Reference: Transplantation. 2021 Oct 1;105(10):2146-2155. doi: 10.1097/TP.0000000000003873.
Impact factor: 4.939
Publication type: Paper in international publication
Authors: Molina, Maria, Vazquez-Sanchez, Teresa, Crespo, Marta, Facundo, Carme, Rodriguez-Ferrero, M feminine Luisa, Ruiz Fuentes, M feminine Carmen, Loinaz, Carmelo, Bernal, Gabriel, Melilli, Edoardo, Bravo, Carlos et al.
DOI: 10.1097/TP.0000000000003873

MMP-10 is Increased in Early Stage Diabetic Kidney Disease and can be Reduced by Renin-Angiotensin System Blockade.

PMID: 31913319
Journal: Scientific Reports
Year: 2020
Reference: Sci Rep. 2020 Jan 8;10(1):26. doi: 10.1038/s41598-019-56856-3.
Impact factor: 3.998
Publication type: Paper in international publication
Authors: Garcia-Fernandez, Nuria, Mora-Gutierrez, Jose Maria, Rodriguez, Jose Antonio, Fernandez-Seara, Maria A, Orbe, Josune, Escalada, Francisco Javier, Soler, Maria Jose, Slon Roblero, Maria Fernanda, Riera, Marta, Paramo, Jose Antonio et al.
DOI: 10.1038/s41598-019-56856-3

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.

The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.