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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

Breakthrough Infections Following mRNA SARS-CoV-2 Vaccination in Kidney Transplant Recipients.

PMID: 35384924
Journal: TRANSPLANTATION
Year: 2022
Reference: Transplantation. 2022 Jul 1;106(7):1430-1439. doi: 10.1097/TP.0000000000004119. Epub 2022 Apr 1.
Impact factor: 4.939
Publication type: Paper in international publication
Authors: Mazuecos, Auxiliadora, Villanego, Florentino, Zarraga, Sofia, Lopez, Veronica, Oppenheimer, Federico, Llinas-Mallol, Laura, Moina, Inigo, Alcalde, Guillermo, Sanchez-Alvarez, Emilio, Pascual, Julio et al.
DOI: 10.1097/TP.0000000000004119

COVID-19 in Patients with Glomerular Disease: Follow-Up Results from the IRoc-GN International Registry.

PMID: 35373130
Journal: Kidney360
Year: 2022
Reference: Kidney360. 2021 Dec 3;3(2):293-306. doi: 10.34067/KID.0006612021. eCollection 2022 Feb 24.
Impact factor: 0
Publication type: Paper in international publication
Authors: Avello, Alejandro, Lightstone, Liz, Turner-Stokes, Tabitha, Griffith, Megan, Torras, Joan, Martinez Valenzuela, Laura, Bestard, Oriol, Geddes, Colin, Flossmann, Oliver, Budge, Kelly L et al.
DOI: 10.34067/KID.0006612021

High intrapatient variability of tacrolimus exposure associated with poorer outcomes in liver transplantation.

PMID: 35373449
Journal: CTS-Clinical and Translational Science
Year: 2022
Reference: Clin Transl Sci. 2022 Jun;15(6):1544-1555. doi: 10.1111/cts.13276. Epub 2022 Apr 19.
Impact factor: 4.689
Publication type: Paper in international publication
Authors: Charco, Ramon, Dopazo, Cristina, Bilbao, Itxarone, Garcia, Sonia, Gomez-Gavara, Concepcion, Caralt, Mireia, Campos-Varela, Isabel, Castells, Lluis, Hidalgo, Ernest, Moreso, Francisco et al.
DOI: 10.1111/cts.13276

Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Mo After a Diagnosis of COVID-19.

PMID: 35320154
Journal: TRANSPLANTATION
Year: 2022
Reference: Transplantation. 2022 May 1;106(5):1012-1023. doi: 10.1097/TP.0000000000004075. Epub 2022 Apr 26.
Impact factor: 4.939
Publication type: Paper in international publication
Authors: Bemelman, Frederike J, du Buf-Vereijken, Peggy W G, van Ginneken, Betty, Maas, Nanda, Vogt, Liffert, van Jaarsveld, Brigit C, Klingenberg-Salahova, Farah, Verhofstede, Sabine, Vervloet, Marc G, Nurmohamed, Azam et al.
DOI: 10.1097/TP.0000000000004075

Kidney transplantation and COVID-19 renal and patient prognosis.

PMID: 33815780
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2021 Mar 26;14(Suppl 1):i21-i29. doi: 10.1093/ckj/sfab030. eCollection 2021 Mar.
Impact factor: 4.452
Publication type: Review in international publication
Authors: Toapanta, Nestor, Torres, Irina B, Sellares, Joana, Chamoun, Betty, Seron, Daniel, Moreso, Francesc et al.
DOI: 10.1093/ckj/sfab030

COVID-19 and its impact on the kidney and the nephrology community.

PMID: 33815779
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2021 Mar 26;14(Suppl 1):i1-i5. doi: 10.1093/ckj/sfab039. eCollection 2021 Mar.
Impact factor: 4.452
Publication type: Editorail in international publication
Authors: Soler, Maria Jose, Batlle, Daniel et al.
DOI: 10.1093/ckj/sfab039

Revisiting the Renin-Angiotensin System.

PMID: 33819521
Journal: MOLECULAR AND CELLULAR ENDOCRINOLOGY
Year: 2021
Reference: Mol Cell Endocrinol. 2021 Jun 1;529:111268. doi: 10.1016/j.mce.2021.111268. Epub 2021 Apr 2.
Impact factor: 4.102
Publication type: Editorail in international publication
Authors: Soler, Maria Jose, Batlle, Daniel et al.
DOI: 10.1016/j.mce.2021.111268

Active bleeding after kidney biopsy: Successful ultrasound-guided direct thrombin embolization into the cortical fistula.

PMID: 33098132
Journal: JOURNAL OF CLINICAL ULTRASOUND
Year: 2021
Reference: J Clin Ultrasound. 2021 May;49(4):390-394. doi: 10.1002/jcu.22939. Epub 2020 Oct 24.
Impact factor: 0.91
Publication type: Letter or abstract
Authors: Escudero-Fernandez, Jose Miguel, Bolufer Cardona, Monica, Perez Lafuente, Mercedes, Montealegre, Carolina, Uriarte, Iciar, Serres-Creixams, Xavier et al.
DOI: 10.1002/jcu.22939

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.

The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.