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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

Management of post-transplant diabetes mellitus: an opportunity for novel therapeutics.

PMID: 35265335
Journal: Clinical Kidney Journal
Year: 2022
Reference: Clin Kidney J. 2021 Jul 10;15(1):5-13. doi: 10.1093/ckj/sfab131. eCollection 2022 Jan.
Impact factor: 4.452
Publication type: Review in international publication
Authors: Montero, Nuria, Oliveras, Laia, Soler, Maria Jose, Cruzado, Josep Maria et al.
DOI: 10.1093/ckj/sfab131

Safety of Obtaining an Extra Biobank Kidney Biopsy Core.

PMID: 35268550
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Mar 7;11(5). pii: jcm11051459. doi: 10.3390/jcm11051459.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Mast, Richard, Vergara, Ander, Agraz, Irene, Leon, Juan Carlos, Bolufer, Monica, Gabaldon, Maria-Alejandra, Seron, Daniel, Bestard, Oriol, Soler, Maria Jose, Garcia-Carro, Clara et al.
DOI: 10.3390/jcm11051459

Bioavailability of once-daily tacrolimus formulations used in clinical practice in the management of De Novo kidney transplant recipients: the better study.

PMID: 34851532
Journal: CLINICAL TRANSPLANTATION
Year: 2022
Reference: Clin Transplant. 2022 Mar;36(3):e14550. doi: 10.1111/ctr.14550. Epub 2021 Dec 17.
Impact factor: 2.863
Publication type: Paper in international publication
Authors: Andres, Amado, Rivera, Constantino Fernandez, Rodriguez, Maria Calvo, Poveda, Jose Luis, Pascual, Julio, Crespo, Marta, Gomez, Gonzalo, Pelegrin, Sheila Cabello, Paul, Javier, Lauzurica, Ricardo et al.
DOI: 10.1111/ctr.14550

Haematological disorders following kidney transplantation.

PMID: 33150431
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2022
Reference: Nephrol Dial Transplant. 2022 Feb 25;37(3):409-420. doi: 10.1093/ndt/gfaa219.
Impact factor: 5.992
Publication type: Paper in international publication
Authors: Malyszko, Jolanta, Basak, Grzegorz, Batko, Krzysztof, Capasso, Giavambatista, Drozd-Sokolowska, Joanna, Krzanowska, Katarzyna, Kulicki, Pawel, Matuszkiewicz-Rowinska, Joanna, Soler, Maria Jose Romeo, Sprangers, Ben et al.
DOI: 10.1093/ndt/gfaa219

Acute tubulointerstitial nephritis induced by checkpoint inhibitors versus classical acute tubulointerstitial nephritis: are they the same disease?

PMID: 33777371
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2020 May 4;14(3):884-890. doi: 10.1093/ckj/sfaa027. eCollection 2021 Mar.
Impact factor: 4.452
Publication type: Paper in international publication
Authors: Draibe, Juliana B, Garcia-Carro, Clara, Martinez-Valenzuela, Laura, Agraz, Irene, Fulladosa, Xavier, Bolufer, Monica, Tango, Ariel, Torras, Joan, Soler, Maria Jose et al.
DOI: 10.1093/ckj/sfaa027

Predictors of severe COVID-19 in kidney transplant recipients in the different epidemic waves: analysis of the Spanish Registry.

PMID: 33756067
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2021
Reference: Am J Transplant. 2021 Jul;21(7):2573-2582. doi: 10.1111/ajt.16579. Epub 2021 Apr 12.
Impact factor: 8.086
Publication type: Paper in international publication
Authors: Villanego, Florentino, Mazuecos, Auxiliadora, Perez-Flores, Isabel M, Moreso, Francesc, Andres, Amado, Jimenez-Martin, Carlos, Molina, Maria, Canal, Cristina, Sanchez-Camara, Luis A, Zarraga, Sofia et al.
DOI: 10.1111/ajt.16579

The STARMEN trial indicates that alternating treatment with corticosteroids and cyclophosphamide is superior to sequential treatment with tacrolimus and rituximab in primary membranous nephropathy.

PMID: 33166580
Journal: KIDNEY INTERNATIONAL
Year: 2021
Reference: Kidney Int. 2021 Apr;99(4):986-998. doi: 10.1016/j.kint.2020.10.014. Epub 2020 Nov 7.
Impact factor: 10.612
Publication type: Paper in international publication
Authors: Espinosa, Mario, Egido, Jesus, Segarra, Alfonso, Lambeau, Gerard, Ronco, Pierre, Wetzels, Jack, Praga, Manuel, Plaisier, Emmanuelle, Shabaka, Amir, Romera, Ana et al.
DOI: 10.1016/j.kint.2020.10.014

Predictors of outcome in a Spanish cohort of patients with Fabry disease on enzyme replacement therapy.

PMID: 33714629
Journal: NEFROLOGIA
Year: 2021
Reference: Nefrologia (Engl Ed). 2021 Mar 10. pii: S0211-6995(21)00031-X. doi: 10.1016/j.nefro.2021.01.002.
Impact factor: 2.033
Publication type: Paper in national publication
Authors: Lopes, Vanessa, Ramos, Carmela, Mendez, Irene, Cao, Mercedes, Dominguez, Fernando, Ortiz, Alberto, Martin-Conde, Maria Luisa, Gutierrez, Maria Jose, Quiroga, Borja, Corchete, Elena et al.
DOI: 10.1016/j.nefro.2021.01.002

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.

The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.