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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

Minimal Change Disease Is Associated With Endothelial Glycocalyx Degradation and Endothelial Activation.

PMID: 35497798
Journal: Kidney International Reports
Year: 2022
Reference: Kidney Int Rep. 2021 Dec 16;7(4):797-809. doi: 10.1016/j.ekir.2021.11.037. eCollection 2022 Apr.
Impact factor: 4.164
Publication type: Paper in international publication
Authors: Bauer, Colin, Piani, Federica, Banks, Mindy, Ordonez, Flor A, de Lucas-Collantes, Carmen, Oshima, Kaori, Schmidt, Eric P, Zakharevich, Igor, Segarra, Alfons, Martinez, Cristina et al.
DOI: 10.1016/j.ekir.2021.11.037

Is humoral and cellular response to SARS-CoV-2 vaccine modified by DMT in patients with multiple sclerosis and other autoimmune diseases?

PMID: 35475363
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jun;28(7):1138-1145. doi: 10.1177/13524585221089540. Epub 2022 Apr 27.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Arrambide, Georgina, Otero-Romero, Susana, Pappolla, Agustin, Tagliani, Paula, Lopez-Maza, Samuel, Cardenas-Robledo, Simon, Esperalba, Juliana, Fernandez-Naval, Candela, Martinez-Gallo, Monica, Castillo, Mireia et al.
DOI: 10.1177/13524585221089540

Acute kidney injury as a risk factor for mortality in oncological patients receiving check-point inhibitors.

PMID: 33547795
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2022
Reference: Nephrol Dial Transplant. 2022 Apr 25;37(5):887-894. doi: 10.1093/ndt/gfab034.
Impact factor: 5.992
Publication type: Paper in international publication
Authors: Garcia-Carro, Clara, Bolufer, Monica, Bury, Roxana, Cataneda, Zaira, Munoz, Eva, Felip, Enriqueta, Lorente, David, Josep Carreras, Maria, Gabaldon, Alejandra, Seron, Daniel et al.
DOI: 10.1093/ndt/gfab034

Predicting Kidney Response to Plasma Exchange in ANCA-Associated Vasculitis: Need for Plausible Models.

PMID: 35410878
Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Year: 2022
Reference: J Am Soc Nephrol. 2022 Jun;33(6):1223-1224. doi: 10.1681/ASN.2022020164. Epub 2022 Apr 11.
Impact factor: 10.121
Publication type: Letter or abstract
Authors: Specks, Ulrich, Casal Moura, Marta, Soler, Maria Jose, Sethi, Sanjeev, Fervenza, Fernando C et al.
DOI: 10.1681/ASN.2022020164

Secondary antibody deficiency is associated with development of infection in kidney transplantation: results of a multicenter study.

PMID: 33064917
Journal: Transplant Infectious Disease
Year: 2021
Reference: Transpl Infect Dis. 2021 Apr;23(2):e13494. doi: 10.1111/tid.13494. Epub 2020 Oct 27.
Impact factor: 2.228
Publication type: Paper in international publication
Authors: Anaya, Fernando, Lopez-Hoyos, Marcos, Rodrigo, Emilio, Arias, Manuel, Perello, Manel, Seron, Daniel, Karanovic, Boris, Ezzahouri, Ikram, Mezzano, Sergio, Jaramillo, Maria et al.
DOI: 10.1111/tid.13494

Focal and segmental glomerulosclerosis associated with COVID-19 infection.

PMID: 33888348
Journal: NEFROLOGIA
Year: 2021
Reference: Nefrologia (Engl Ed). 2021 Apr 19. pii: S0211-6995(21)00058-8. doi: 10.1016/j.nefro.2021.03.002.
Impact factor: 2.033
Publication type: Letter or abstract
Authors: LeonRoman, Juan, Vergara, Ander, Agraz, Irene, Garcia-Carro, Clara, Bermejo, Sheila, Gabaldon, Alejandra, Soler, Maria Jose et al.
DOI: 10.1016/j.nefro.2021.03.002

Surgeon preimplantation macroscopic graft appraisal improves risk stratification of deceased kidney donors: a prospective study.

PMID: 33887895
Journal: Minerva urology and nephrology
Year: 2021
Reference: Minerva Urol Nephrol. 2021 Apr 22. pii: S2724-6051.21.04345-7. doi: 10.23736/S2724-6051.21.04345-7.
Impact factor: 0
Publication type: Paper in international publication
Authors: Miret, Enric, Moreso, Francesc, Toapanta, Nestor, Lorente, David, Triquell, Marina, Pont, Teresa, Perez-Hoyos, Santiago, Seron, Daniel, Morote, Juan, Trilla, Enrique et al.
DOI: 10.23736/S2724-6051.21.04345-7

EFFECT OF RAMIPRIL ON KIDNEY, LUNG AND HEART ACE2 IN A DIABETIC MICE MODEL.

PMID: 33811970
Journal: MOLECULAR AND CELLULAR ENDOCRINOLOGY
Year: 2021
Reference: Mol Cell Endocrinol. 2021 Jun 1;529:111263. doi: 10.1016/j.mce.2021.111263. Epub 2021 Mar 31.
Impact factor: 4.102
Publication type: Paper in international publication
Authors: Soler, Maria Jose, Seron, Daniel, Garcia-Carro, Clara, Vergara, Ander, Jacobs-Cacha, Conxita, Molina-Van den Bosch, Mireia, Dominguez-Baez, Pamela, Benito, Begona et al.
DOI: 10.1016/j.mce.2021.111263

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.

The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.