Rheumatology
The Rheumatology Research Group (GRR) is focused on translational research in immunity-mediated inflammatory diseases (IMIDA), mainly in the area of rheumatology. The GRR is a multidisciplinary group made up of clinical specialists, biologists, bioinformaticians and laboratory technicians. The different research lines of the GRR emphasize the use of high-performance technologies for the study at the cellular and molecular level of the immununopathology of IMIDA, mainly chronic inflammatory arthritis and autoimmune systemic diseases.
At the clinical level, we have developed lines of research in very diverse areas of rheumatology, including chronic inflammatory arthritis (rheumatoid arthritis, spondyloarthropathies), systemic autoimmune diseases (lupus, myositis, Sjögren's syndrome), the study of musculoskeletal imaging, pediatric rheumatology (juvenile idiopathic arthritis, autoimmune systemic diseases, autoinflammatory syndromes), central sensitization syndromes and the study of bone metabolism. One of the main objectives of the GRR is the coordination of basic and clinical research to accelerate the transfer of knowledge to clinical practice and thus improve the quality of life of patients.
Publications
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.
PMID: 34861974
Journal: BIOLOGICAL PSYCHIATRY
Year: 2022
Reference: Biol Psychiatry. 2022 Feb 1;91(3):313-327. doi: 10.1016/j.biopsych.2021.05.029. Epub 2021 Sep 9.
Impact factor: 13.382
Publication type: Paper in international publication
Authors: Anjorin, Adebayo; Watson, Hunna J; Adams, Mark; Awasthi, Swapnil; Gandal, Michael; Hafferty, Jonathan D; Hishimoto, Akitoyo; Kim, Minsoo; Okazaki, Satoshi; Otsuka, Ikuo et al.
DOI: 10.1016/j.biopsych.2021.05.029
Multidisciplinary models for pregnancy care in patients with rheumatic diseases: Clinical experiences and experts opinion.
PMID: 35156620
Journal: European journal of rheumatology
Year: 2022
Reference: Eur J Rheumatol. 2022 Feb 14. doi: 10.5152/eujrheum.2022.20012.
Impact factor: 0
Publication type: Paper in international publication
Authors: Vela, Paloma; Trujillo, Elisa; Pego Reigosa, Jose Maria; Polo, Ana; Pluma, Andrea; Alsina, Laia; Baniandres, Ofelia; Caliz, Rafael; Casellas, Manel; Grados, Dolors et al.
DOI: 10.5152/eujrheum.2022.20012
Identifying mindfulness and acceptance as mediators between negative affect, functional disability and emotional distress in patients with fibromyalgia.
PMID: 34796836
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2022
Reference: Clin Exp Rheumatol. 2022 Jun;40(6):1102-1111. doi: 10.55563/clinexprheumatol/uzzejn. Epub 2021 Nov 18.
Impact factor: 4.473
Publication type: Paper in international publication
Authors: Maurel, Sara; Saez-Francas, Naia; Calvo, Natalia; Alegre-Martin, Jose; Castro-Marrero, Jesus et al.
DOI:
Trajectories in early rheumatoid arthritis related fatigue over 10 years: results from the ESPOIR cohort.
PMID: 34596027
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2022
Reference: Clin Exp Rheumatol. 2022 Jul;40(7):1361-1367. doi: 10.55563/clinexprheumatol/kk1ndf. Epub 2021 Sep 21.
Impact factor: 4.473
Publication type: Paper in international publication
Authors: Marsal, Sara; Olive, Alejandro; Fautrel, Bruno; Guillemin, Francis; Combe, Bernard; Rodriguez-Muguruza, Samantha; Valero, Oliver; Lukas, Cedric et al.
DOI: 10.55563/clinexprheumatol/kk1ndf
Targeting of the CD80/86 proinflammatory axis as a therapeutic strategy to prevent severe COVID-19.
PMID: 34075090
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Jun 1;11(1):11462. doi: 10.1038/s41598-021-90797-0.
Impact factor: 4.38
Publication type: Paper in international publication
Authors: Julia, Antonio, Bonafonte-Pardas, Irene, Gomez, Antonio, Lopez-Lasanta, Maria, Lopez-Corbeto, Mireia, Martinez-Mateu, Sergio H, Llados, Jordi, Rodriguez-Nunez, Ivan, Myers, Richard M, Marsal, Sara et al.
DOI: 10.1038/s41598-021-90797-0
News
Funded by the European Union, this project coordinated by the Vall d'Hebron Research Institute (VHIR) seeks to develop more effective therapies by creating new combinations of existing drugs
The head of the Rheumatology Service at Vall d'Hebron University Hospital and of the Rheumatology research group at VHIR is a highly accomplished rheumatologist with a distinguished career in the field.
It is the first international multi-centre clinical trial to analyse the safety and effect of this treatment for an autoimmune disease.