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A 2-Part, Randomized, Double-Blind, Placebo-Controlled Study in Participants with Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping to Evaluate the Safety and Efficacy of ENTR-601-44 (ELEVATE-44)

  • Protocol code: ENTR-601-44-201
  • EudraCT code: 2024-517584-23-00
  • Pathology: Duchenne muscular dystrophy
  • Pharmac: Hydrocortisone
  • Promoter: Entrada Theraputics, Inc.
  • Principal investigator:  Gómez Andrés, David
  • Research group:  Teràpies i Innovació en Neuropediatria i altres malalties rares pediàtriques.
  • Service: Neurologia pediàtrica
  • Phase: Fase I
  • Recruiting: Open
  • Status: Activo

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
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Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
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Estudio de tolerabilidad y aceptación de dos fórmulas magistrales de hidrocortisona oral para pediatría

  • Protocol code: HIDROGUM21
  • EudraCT code: 2021-001069-20
  • Pathology: Adrenal hyperplasia or isolated primary adrenal insufficiency or panhypopituitarism (secondary or tertiary adrenal insufficiency).
  • Promoter: Hospital Universitario Vall Hebron
  • Principal investigator:  Parramon Teixido, Carlos Javier
  • Research group:  Recerca en farmacia bàsica, translacional i clínica
  • Service: Farmàcia
  • Phase: Fase IV
  • Recruiting: Open
  • Status: Activo

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Recombination Chimeric Monoclonal Antibody CH.14.18

  • Protocol code: SIOPENRNET002
  • EudraCT code: 2006-001489-17
  • Pathology: Neuroblastoma
  • Pharmac: Anticuerpo monoclonal recombinante antiGDch14.18.
  • Promoter: Dra. Victoria Castel (Hospital La Fe de Valencia)
  • Principal investigator:  Moreno Martín-Retortillo, Lucas
  • Research group:  Càncer i malalties hematològiques infantils
  • Service: Oncohematologia Pediàtrica
  • Phase: Fase III
  • Recruiting: Open
  • Status: Activo

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A phase III, Multicenter, Randomized, Double-blind Study to Assess Efficacy and Safety of Two Doses of Crizanlizumab versus placebo, with or without Hydroxyurea/ Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients with Vaso-Occlusive Crises (STAND)

  • Protocol code: CSEG101A2301
  • EudraCT code: 2017-001746-10
  • Pathology: Sickle cell disease
  • Pharmac: Crizanlizumab
  • Promoter: Novartis Pharma AG
  • Principal investigator:  Beneitez Pastor, David
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Hematologia
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Finalizado

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Estudio en fase III, aleatorizado, abierto, con control activo, multicéntrico, para evaluar la eficacia y la seguridad de crovalimab frente a eculizumab en pacientes adultos y adolescentes con hemoglobinuria paroxística nocturna (HPN) actualmente tratada con inhibidores del complemento

  • Protocol code: BO42161
  • EudraCT code: 2020-000597-26
  • Pathology: Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Pharmac: CROVALIMAB
  • Promoter: F. Hoffmann-La Roche AG (Switzerland)
  • Principal investigator:  Beneitez Pastor, David
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Hematologia
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Finalizado

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Estudio de fase 3, multicéntrico, aleatorizado, doble ciego, controlado con placebo y de grupos paralelos con una extensión abierta para evaluar la eficacia y la seguridad de rilzabrutinib por vía oral (PRN1008) en adultos y adolescentes con trombocitopenia inmunitaria (TPI) persistente o crónica

  • Protocol code: PRN1008-018
  • EudraCT code: 2020-002063-60
  • Pathology: Immune Thrombocytopenia (ITP)
  • Pharmac: Rilzabrutinib (PRN1008)
  • Promoter: Principia Biopharma Inc. (United States)
  • Principal investigator:  Valcarcel Ferreiras, David
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Hematologia
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Finalizado

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Ensayo multinacional, abierto, aleatorizado y controlado para investigar la eficacia y la seguridad de NNC0365-3769 (Mim8) en adultos y adolescentes con hemofilia A con o sin inhibidores

  • Protocol code: NN7769-4514
  • EudraCT code: 2020-001048-24
  • Pathology: Hemofilia A con inhibidores
  • Pharmac: NNC0365-3769 (Mim8)
  • Promoter: Novo Nordisk A/S
  • Principal investigator:  Benitez Hidalgo, Olga
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Hematologia
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Cerrado

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Estudio abierto para investigar la eficacia, la seguridad y la farmacocinética de la profilaxis con concizumab en niños menores de 12 años con hemofilia A o B con o sin inhibidores

  • Protocol code: NN7415-4616
  • EudraCT code: 2020-000504-11
  • Pathology: Haemophilia A or B with or without inhibitors
  • Pharmac: Concizumab
  • Promoter: Novo Nordisk A/S
  • Principal investigator:  Benitez Hidalgo, Olga
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Hematologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Activo

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A phase 3b open-label, multicenter study evaluating physicalactivity and joint health in previously treated patients =12 years of age with severehaemophilia A treated with intravenous recombinant coagulation factor VIII FcvonWillebrand Factor-XTEN fusion protein (rFVIIIFc-VWF-XTEN; efanesoctocogalfa) for 24 months.

  • Protocol code: BIVV001-001
  • EudraCT code: 2022-500275-31-00
  • Pathology: Haemophilia A
  • Pharmac: Recombinant Coagulation Factor VIII Fc-von Willebrand Factor-XTEN Fusion Protein (rFVIIIFc-VWF-XTEN; BIVV001)
  • Promoter: Swedish Orphan Biovitrum AB (publ) (Sweden)
  • Principal investigator:  Benitez Hidalgo, Olga
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Hematologia
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Finalizado

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Estudio de dosis escalonadas para evaluar la farmacocinética, eficacia y seguridad de apotransferrina en pacientes con atransferrinemia.

  • Protocol code: MD2009.04
  • EudraCT code: 2009-017409-13
  • Pathology: Congenital atransferrinaemia/ hypotransferrinaemia
  • Pharmac: Apotransferrin
  • Promoter: Sanquin Plasma Products BV
  • Principal investigator:  Díaz de Heredia Rubio, Maria Cristina
  • Research group:  Childhood Cancer and Blood Disorders
  • Service: Pediatric Oncohematology
  • Phase: Fase II
  • Recruiting: Open
  • Status: Activo

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Estudio fase1/2, abierto, multicentrico, first in human para evualar la seguridad, tolerabilidad, pk y actividad atnitumoral de repotrectinib (TPX-0005) en pacientes con TSA y reordenamiento ALK, ROS1, o NTRK1-3 Rearrangements (TRIDENT-1)

  • Protocol code: TPX-0005-01
  • EudraCT code: 2016-003616-13
  • Pathology: Advanced solid tumors
  • Pharmac: TPX-0005
  • Promoter: Turning Point Therapeutics, Inc.
  • Principal investigator:  Felip Font, Enriqueta
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Oncologia
  • Phase: Phase I
  • Recruiting: Open
  • Status: Activo

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Estudio fase 1b, abierto, de un solo brazo de tratamiento con Epcoritamab en pacientes pediátricos con neoplasias de células B maduras recidivantes/refractarias.

  • Protocol code: M20-429
  • EudraCT code: 2021-004555-16
  • Pathology: Relapsed/Refractory Aggressive Mature B-cell Neoplasms
  • Pharmac: Epcoritamab
  • Promoter: AbbVie Deutschland GmbH & Co. KG
  • Principal investigator:  Hladun Alvaro, Raquel
  • Research group:  Childhood Cancer and Blood Disorders
  • Service: Pediatric Oncohematology
  • Phase: Phase I
  • Recruiting: Closed
  • Status: Cerrado

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FaR-RMS – Un estudio global para niños y adultos con Rabdomiosarcoma recién diagnosticado y recidivante

  • Protocol code: RG_17-247
  • EudraCT code: 2018-000515-24
  • Pathology: Rhabdoyosarcoma
  • Pharmac: Irinotecan with IVA (IrIVA).
  • Promoter: University of Birmingham
  • Principal investigator:  Hladun Alvaro, Raquel
  • Research group:  Childhood Cancer and Blood Disorders
  • Service: Pediatric Oncohematology
  • Phase: Phase I
  • Recruiting: Open
  • Status: Activo

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Ensayo fase 1 / 2 para evaluar la seguridad y la eficacia de AZD0486 en pacientes adolescentes y adultos con leucemia linfoblástica aguda de células B en recaída o refractarios.

  • Protocol code: D7405C00001
  • EudraCT code: 2023-505840-20-00
  • Pathology: B-Cell Acute Lymphoblastic Leukaemia
  • Pharmac: AZD0486
  • Promoter: Astrazeneca AB (Sweden)
  • Principal investigator:  Barba Suñol, Pere
  • Research group:  Hematologia Experimental
  • Service: Hematologia
  • Phase: Phase I
  • Recruiting: Open
  • Status: Activo

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Estudio en fase III, aleatorizado, doble ciego, controlado con placebo y de dosis única para evaluar la eficacia y la seguridad de suvratoxumab en adultos y adolescentes con ventilación mecánica para la prevención de la neumonía nosocomial

  • Protocol code: AR-320-003
  • EudraCT code: 2021-004979-14
  • Pathology: Prevención de la neumonía nosocomial
  • Pharmac: Suvratoxumab
  • Promoter: Aridis Pharmaceuticals
  • Principal investigator:  Ferrer Roca, Ricard
  • Research group:  Shock, Disfunció Orgànica i Ressucitació
  • Service: UCI
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Cerrado

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Protocolo NOPHO-DBH AML 2012 Estudio de investigación para el tratamiento de niños y adolescentes con leucemia mieloide aguda de 0 a 18 años.

  • Protocol code: NOPHO-DBH-AML-2012
  • EudraCT code: 2012-002934-35
  • Pathology: Acute Myeloid Leukemia (Pediatric 0-18 years)
  • Pharmac: NOPHO-DBH AML 2012 Protocol
  • Promoter: Västra Götaland Regionen
  • Principal investigator:  Murillo Sanjuán , Laura
  • Research group:  Childhood Cancer and Blood Disorders
  • Service: Oncohematologia Ped.
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Finalizado

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Ensayo abierto de extensión para evaluar la seguridad a largo plazo de ZX008 (clorhidrato de fenfluramina) en solución oral como tratamiento adyuvante para convulsiones en pacientes con trastornos infrecuentes de convulsiones tales como encefalopatías epilépticas incluidos el síndrome de Dravet y el síndrome de Lennox-Gastaut

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
Legitimation: Your consent. The data requested is necessary and your request cannot be processed if you do not provide them.
Transfers: Your data will not be transferred to third parties except to the Principal Investigator who leads the research in order to be able to respond to your query.
Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.

A Phase 3, Multicenter, 12-Week, Double-Blind,Placebo Controlled Study to Evaluate the Safety and Efficacy of Atogepant for the Preventive Treatment of Episodic Migraine in Pediatric Subjects 6 to 17 years of age/ Estudio de fase 3, multicéntrico, de 12 semanas, doble ciego y controlado con placebo para evaluar la seguridad y eficacia de Atogepant para el tratamiento preventivo de la migraña episódica en sujetos pediátricos de 6 a 17 años de edad

  • Protocol code: M21-201
  • EudraCT code: 2022-501100-94-00
  • Pathology: Episodic Migraine
  • Pharmac: Atogepant
  • Promoter: Abbvie
  • Principal investigator:  Pozo Rosich, Patricia
  • Research group:  Cefalea i dolor neurològic
  • Service: Neurology
  • Phase: Phase III
  • Recruiting: Open
  • Status: Activo

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I have read and accept the data protection policy *.
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This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
Legitimation: Your consent. The data requested is necessary and your request cannot be processed if you do not provide them.
Transfers: Your data will not be transferred to third parties except to the Principal Investigator who leads the research in order to be able to respond to your query.
Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.

Estudio multicéntrico, abierto, de extensión para evaluar la seguridad a largo plazo de Atogepant en sujetos pediátricos de 6 a 17 años de edad con migraña episódica/ A Multicenter, Open-label, Extension Study to Evaluate the Long-term Safety of Atogepant in Pediatric Subjects 6 to 17 years of age with Episodic Migraine

  • Protocol code: M21-199
  • EudraCT code: 2022-501099-24-00
  • Pathology: Migraña
  • Pharmac: Atogepant
  • Promoter: Abbvie
  • Principal investigator:  Pozo Rosich, Patricia
  • Research group:  Headache and Neurological Pain
  • Service: Neurology
  • Phase: Phase III
  • Recruiting: Open
  • Status: Activo

Contact Form

I have read and accept the data protection policy *.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
Legitimation: Your consent. The data requested is necessary and your request cannot be processed if you do not provide them.
Transfers: Your data will not be transferred to third parties except to the Principal Investigator who leads the research in order to be able to respond to your query.
Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.

Estudio fase 3 prospectivo, abierto, multicéntrico y de extensión de los estudios Fase 3, para evaluar la seguridad y tolerabilidad a largo plazo de Soticlestat como tratamiento adyuvante en pacientes con Síndrome Dravet o Síndrome de Lennox-Gastaut (ENDYMION 2)

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I have read and accept the data protection policy *.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
Legitimation: Your consent. The data requested is necessary and your request cannot be processed if you do not provide them.
Transfers: Your data will not be transferred to third parties except to the Principal Investigator who leads the research in order to be able to respond to your query.
Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.