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Cardiovascular Diseases

Cardiovascular Diseases group is a translational research group within the Cardiology Department of Vall d’Hebron Hospital that performs laboratory, clinical and epidemiological research. In the CIBERCV network we are within the topic of descriptor 2 “Arterial disease, thrombosis and myocardial ischemia-reperfusion injury”. Our contributions in these topics address the following lines: 

  • Myocardial ischemia-reperfusion injury (i.e. mechanisms of endogenous cardioprotection, ischemic conditioning and remodeling), 
  • Coronary artery disease (i.e. genetic factors involved in coronary artery disease, determinants of thrombotic complications and prognosis), 
  • Aortic diseases (i.e. determinants of aorta dilatation, aortic biomechanics abnormalities in Marfan´s syndrome, and new imaging methods), 
  • Congenital/familiar heart diseases (i.e. genetic determinants and prognosis factors). 

In the CIBERESP network, our group is interested in the study of effectiveness/cost-effectiveness of cardiovascular interventions, health outcome research and methods in clinical research. The group has 19 principal investigators, 32 active projects and clinical trial and has been done 142 publications in 2020.

Publications

The time has come to change how emergency physicians evaluate chest pain in women.

PMID: 35833761
Journal: Emergencias
Year: 2022
Reference: Emergencias. 2022 Aug;34(4):253-254.
Impact factor: 3.881
Publication type: Editorail in international publication
Authors: Sambola, Antonia, Soriano-Colome, Toni et al.
DOI:

Left ventricular noncompaction: a disease or a phenotypic trait?

PMID: 35820566
Journal: Revista espanola de cardiologia (English ed.)
Year: 2022
Reference: Rev Esp Cardiol (Engl Ed). 2022 Jul 9. pii: S1885-5857(22)00183-9. doi: 10.1016/j.rec.2022.07.002.
Impact factor: 0
Publication type: Review in national publication
Authors: Ferreira-Gonzalez, Ignacio, Rodriguez-Palomares, Jose F, Casas, Guillem et al.
DOI: 10.1016/j.rec.2022.07.002

Magnetic Resonance Assessment of Left Ventricular Ejection Fraction at Any Time Post-Infarction for Prediction of Subsequent Events in a Large Multicenter STEMI Registry.

PMID: 34137478
Journal: JOURNAL OF MAGNETIC RESONANCE IMAGING
Year: 2022
Reference: J Magn Reson Imaging. 2022 Aug;56(2):476-487. doi: 10.1002/jmri.27789. Epub 2021 Jun 16.
Impact factor: 4.813
Publication type: Paper in international publication
Authors: Bodi, Vicente, Gavara, Jose, Lopez-Lereu, Maria P, Ortiz-Perez, Jose T, Rodriguez-Palomares, Jose F, Lorenzatti, Daniel, Valente, Filipa, Chorro, Francisco J, Moratal, David, Nunez, Eduardo et al.
DOI: 10.1002/jmri.27789

Influenza myocarditis in paediatric patients.

PMID: 34889174
Journal: CARDIOLOGY IN THE YOUNG
Year: 2022
Reference: Cardiol Young. 2022 Jul;32(7):1188-1190. doi: 10.1017/S1047951121004777. Epub 2021 Dec 10.
Impact factor: 1.093
Publication type: Paper in international publication
Authors: Gran, Ferran, Dolader, Paola, Balcells, Joan et al.
DOI: 10.1017/S1047951121004777

Revascularized ST-segment elevation myocardial infarction. Temporal trends in contemporary therapies and impact on outcomes.

PMID: 34887210
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2021
Reference: Rev Esp Cardiol (Engl Ed). 2021 Dec 6. pii: S1885-5857(21)00323-6. doi: 10.1016/j.rec.2021.10.011.
Impact factor: 4.753
Publication type: Paper in national publication
Authors: Ferreira-Gonzalez, Ignacio, Barrabes, Jose A, Pijoan, Jose Ignacio, Ribera, Aida, Marsal, Josep R, Faixedas, Maria T, Tizon-Marcos, Helena, Rojas, Sergio, Labata, Carlos, Cardenas, Merida et al.
DOI: 10.1016/j.rec.2021.10.011

Perivalvular Extension of Infective Endocarditis after Transcatheter Aortic Valve Replacement.

PMID: 34894124
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2021
Reference: Clin Infect Dis. 2021 Dec 11. pii: 6459521. doi: 10.1093/cid/ciab1004.
Impact factor: 9.079
Publication type: Paper in international publication
Authors: Correia de Lima, Valter, Panagides, Vassili, Del Val, David, Abdel-Wahab, Mohamed, Mangner, Norman, Durand, Eric, Ihlemann, Nikolaj, Urena, Marina, Salido, Luisa, Alkhodair, Abdullah et al.
DOI: 10.1093/cid/ciab1004

Excimer laser coronary atherectomy for uncrossable coronary lesions. A multicenter registry.

PMID: 33232583
Journal: CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
Year: 2021
Reference: Catheter Cardiovasc Interv. 2021 Dec 1;98(7):1241-1249. doi: 10.1002/ccd.29392. Epub 2020 Nov 24.
Impact factor: 2.692
Publication type: Paper in international publication
Authors: Ojeda, Soledad, Azzalini, Lorenzo, Suarez de Lezo, Javier, Johal, Gurpreet S, Gonzalez, Rafael, Barman, Nitin, Hidalgo, Francisco, Bellera, Neus, Dangas, George, Jurado-Roman, Alfonso et al.
DOI: 10.1002/ccd.29392

Are Aortic Root and Ascending Aorta Diameters Measured by the Pediatric versus the Adult American Society of Echocardiography Guidelines Interchangeable?

PMID: 34830571
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Nov 14;10(22). pii: jcm10225290. doi: 10.3390/jcm10225290.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Sabate-Rotes, Anna, Servato, Maria Luz, Teixido-Tura, Gisela, Valente, Filipa, Fernandez-Galera, Ruben, Casas, Guillem, Lopez-Sainz, Angela, Gonzalez-Alujas, M Teresa, Sao-Aviles, Augusto, Ferreira, Ignacio et al.
DOI: 10.3390/jcm10225290

Ductal stenting in congenital heart disease with duct dependent pulmonary blood flow.

PMID: 32474004
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2020
Reference: Rev Esp Cardiol. 2020 Oct;73(10):859-861. doi: 10.1016/j.rec.2020.03.014. Epub 2020 May 27.
Impact factor: 4.642
Publication type: Letter whit IF
Authors: Marfil-Godoy, Laura, Marti-Aguasca, Gerard, Ferrer-Menduina, Queralt, Giralt-Garcia, Gemma, Betrian-Blasco, Pedro et al.
DOI: 10.1016/j.rec.2020.03.014

High incidence of subclinical atrial fibrillation in patients with syncope monitored with implantable cardiac monitor.

PMID: 32470530
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2020
Reference: Int J Cardiol. 2020 Oct 1;316:110-116. doi: 10.1016/j.ijcard.2020.05.078. Epub 2020 May 27.
Impact factor: 3.229
Publication type: Paper in international publication
Authors: Ignacio, Ferreira Gonzalez, Jaume, Francisco-Pascual, Aleix, Olivella Sanemeterio, Nuria, Rivas Gandara, Jordi, Perez Rodon, Begona, Benito, Alba, Santos Ortega, Angel, Moya Mitjans, Julian, Rodriguez Garcia, Isabel, Llerena Butron Sandra et al.
DOI: 10.1016/j.ijcard.2020.05.078

AORTIC COMPLICATIONS IN MARFAN SYNDROME. SHOULD WE ANTICIPATE PREVENTIVE AORTIC ROOT SURGERY?

PMID: 31589859
Journal: ANNALS OF THORACIC SURGERY
Year: 2020
Reference: Ann Thorac Surg. 2020 Jun;109(6):1850-1857. doi: 10.1016/j.athoracsur.2019.08.096. Epub 2019 Oct 4.
Impact factor: 3.639
Publication type: Paper in international publication
Authors: Martinez, Daniel, Martin, Carlos, Evangelista, Arturo, Serrano-Fiz, Santiago, Villar, Susana, Ospina, Victor, Monivas, Vanessa, Mingo, Susana, Forteza, Alberto, Sanchez, Violeta et al.
DOI: 10.1016/j.athoracsur.2019.08.096

Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain.

PMID: 32410687
Journal: Health and Quality of Life Outcomes
Year: 2020
Reference: Health Qual Life Outcomes. 2020 May 14;18(1):140. doi: 10.1186/s12955-020-01312-4.
Impact factor: 2.344
Publication type: Paper in international publication
Authors: Loi, Bruno, Saba, Luca, Francone, Marco, Mancone, Massimo, Berzina, Marina, Erglis, Andrejs, Vaitiekiene, Audrone, Zajanckauskiene, Laura, Haran, Tomasz, Suckiel, Malgorzata Ilnicka et al.
DOI: 10.1186/s12955-020-01312-4

Gaucher disease type 3c: New patients with unique presentations and review of the literature.

PMID: 31130326
Journal: MOLECULAR GENETICS AND METABOLISM
Year: 2019
Reference: Mol Genet Metab. 2019 Jun;127(2):138-146. doi: 10.1016/j.ymgme.2019.05.011. Epub 2019 May 21.
Impact factor: 3.61
Publication type: Paper in international publication
Authors: Del Toro, Mireia, Spiegel, Ronen, Gutstein, Ariel, Shafir, Gideon, Cohen, Ian J, Barrabes, Jose A, Feldman, Hagit Baris, Kurolap, Alina et al.
DOI: 10.1016/j.ymgme.2019.05.011

Postural Orthostatic Tachycardia Syndrome and Vasospastic Angina: Therapeutic Approach to a Previously Unreported Association.

PMID: 30322723
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Jun;72(6):509-510. doi: 10.1016/j.rec.2018.05.043. Epub 2018 Oct 12.
Impact factor: 5.078
Publication type: Paper in national publication
Authors: Casas, Guillem, Rivas-Gandara, Nuria, Francisco-Pascual, Jaume, Moya-Mitjans, Angel, Garcia-Dorado, David et al.
DOI: 10.1016/j.rec.2018.05.043

Diagnostic Yield and Economic Assessment of a Diagnostic Protocol With Systematic Use of an External Loop Recorder for Patients With Palpitations.

PMID: 29805092
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Jun;72(6):473-478. doi: 10.1016/j.rec.2018.04.007. Epub 2018 May 24.
Impact factor: 5.078
Publication type: Paper in national publication
Authors: Moya-Mitjans, Angel, Garcia-Dorado, David, Mila-Pascual, Laia, Rivas-Gandara, Nuria, Francisco-Pascual, Jaume, Santos-Ortega, Alba, Roca-Luque, Ivo, Perez-Rodon, Jordi et al.
DOI: 10.1016/j.rec.2018.04.007

Author Correction: Selective Inhibition of Succinate Dehydrogenase in Reperfused Myocardium with Intracoronary Malonate Reduces Infarct Size.

PMID: 30996245
Journal: Scientific Reports
Year: 2019
Reference: Sci Rep. 2019 Apr 17;9(1):6395. doi: 10.1038/s41598-019-42591-2.
Impact factor: 4.011
Publication type: Letter or abstract
Authors: Valls-Lacalle, Laura, Barba, Ignasi, Miro-Casas, Elisabet, Ruiz-Meana, Marisol, Rodriguez-Sinovas, Antonio, Garcia-Dorado, David et al.
DOI: 10.1038/s41598-019-42591-2

Comments on the 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases.

PMID: 29425610
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2018
Reference: Rev Esp Cardiol (Engl Ed). 2018 Feb;71(2):74-78. doi: 10.1016/j.rec.2017.11.028.
Impact factor: 5.166
Publication type: Editorial in national publication
Authors: Ferreira-Gonzalez, Ignacio, Jimenez Navarro, Manuel, Marin, Francisco, Perez de Isla, Leopoldo, Rodriguez Padial, Luis, Sanchez Fernandez, Pedro Luis, Sionis, Alessandro, Vazquez Garcia, Rafael, Evangelista, Arturo, Alfonso, Fernando et al.
DOI: 10.1016/j.rec.2017.11.028

Computed Tomography Aortic Valve Calcium Scoring in Patients With Aortic Stenosis.

PMID: 29555836
Journal: Circulation-Cardiovascular Imaging
Year: 2018
Reference: Circ Cardiovasc Imaging. 2018 Mar;11(3):e007146. doi: 10.1161/CIRCIMAGING.117.007146.
Impact factor: 6.221
Publication type: Paper in international publication
Authors: Evangelista, Arturo, Pawade, Tania, Clavel, Marie-Annick, Tribouilloy, Christophe, Dreyfus, Julien, Mathieu, Tiffany, Tastet, Lionel, Renard, Cedric, Gun, Mesut, Jenkins, William Steven Arthur et al.
DOI: 10.1161/CIRCIMAGING.117.007146

Anatomical and clinical predictors of valve dysfunction and aortic dilation in bicuspid aortic valve disease.

PMID: 28864719
Journal: HEART
Year: 2018
Reference: Heart. 2018 Apr;104(7):566-573. doi: 10.1136/heartjnl-2017-311560. Epub 2017 Sep 1.
Impact factor: 5.42
Publication type: Paper in international publication
Authors: Carro, Amelia, Evangelista, Arturo, Gallego, Pastora, Calvo-Iglesias, Francisco, Bermejo, Javier, Robledo-Carmona, Juan, Sanchez, Violeta, Saura, Daniel, Arnold, Roman, Teixido, Gisela et al.
DOI: 10.1136/heartjnl-2017-311560

Overview of mitral regurgitation in Europe: results from the European Registry of mitral regurgitation (EuMiClip).

PMID: 29529191
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2018
Reference: Eur Heart J Cardiovasc Imaging. 2018 May 1;19(5):503-507. doi: 10.1093/ehjci/jey011.
Impact factor: 8.336
Publication type: Review in international publication
Authors: Tanner, Felix C, Cassani, Daniela, Faletra, Francesco F, Leo, Laura A, Martinez, Amparo, Matabuena, Javier, Grande-Trillo, Antonio, Alonso-Rodriguez, David, Mesa, Dolores, Gonzalez-Alujas, Teresa et al.
DOI: 10.1093/ehjci/jey011

Primary distal renal tubular acidosis: novel findings in patients studied by next-generation sequencing.

PMID: 26571219
Journal: PEDIATRIC RESEARCH
Year: 2016
Reference: Pediatr Res. 2016 Mar;79(3):496-501. doi: 10.1038/pr.2015.243. Epub 2015 Nov 16.
Impact factor: 2.761
Publication type: Paper in international publication
Authors: Hernandez, Olaya, Gomez, Juan, Gil-Pena, Helena, Santos, Fernando, Coto, Eliecer, Arango, Ana, Cantos, Virginia, Chocron, Sara, Vergara, Ines, Madrid, Alvaro et al.
DOI: 10.1038/pr.2015.243

Integrating Multimodal Imaging in Clinical Practice: The Importance of a Multidisciplinary Approach.

PMID: 27052126
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2016
Reference: Rev Esp Cardiol (Engl Ed). 2016 May;69(5):477-9. doi: 10.1016/j.rec.2016.01.019. Epub 2016 Apr 3.
Impact factor: 1.455
Publication type: Paper in national publication
Authors: Rodriguez-Palomares, Jose F, Garcia Fernandez, Miguel A, Barba Cosials, Joaquin et al.
DOI: 10.1016/j.rec.2016.01.019

Cardiac Imaging 2015: A Selection of Topical Issues.

PMID: 26752219
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2016
Reference: Rev Esp Cardiol (Engl Ed). 2016 Mar;69(3):286-93. doi: 10.1016/j.rec.2015.10.003. Epub 2015 Dec 30.
Impact factor: 4.596
Publication type: Paper in international publication
Authors: Barba-Cosials, Joaquin, Perez de Isla, Leopoldo, Aguade-Bruix, Santiago, Rodriguez-Palomares, Jose F, Saura, Daniel, Lopez-Fernandez, Teresa et al.
DOI: 10.1016/j.rec.2015.10.003

Increased von Willebrand factor, P-selectin and fibrin content in occlusive thrombus resistant to lytic therapy.

PMID: 26962963
Journal: THROMBOSIS AND HAEMOSTASIS
Year: 2016
Reference: Thromb Haemost. 2016 Jun 2;115(6):1129-37. doi: 10.1160/TH15-12-0985. Epub 2016 Mar 10.
Impact factor: 5.255
Publication type: Paper in international publication
Authors: Francisco, Jaume, Barrabes, Jose A, Figueras, Jaume, Baneras, Jordi, Otaegui, Imanol, Rojas, Angeles, Vilardosa, Ursula, Montaner, Joan, Garcia-Dorado, David, Ruiz-Meana, Marisol et al.
DOI: 10.1160/TH15-12-0985

Nuclear cardiology: role in the world of multimodality cardiac imaging.

PMID: 25944190
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2015
Reference: Rev Esp Cardiol (Engl Ed). 2015 Jun;68(6):460-4. doi: 10.1016/j.rec.2015.03.001. Epub 2015 May 2.
Impact factor: 3.792
Publication type: Paper in national publication
Authors: Rodriguez-Palomares, Jose F, Aguade-Bruix, Santiago et al.
DOI: 10.1016/j.rec.2015.03.001

Effects of the Selective Stretch-Activated Channel Blocker GsMtx4 on Stretch-Induced Changes in Refractoriness in Isolated Rat Hearts and on Ventricular Premature Beats and Arrhythmias after Coronary Occlusion in Swine.

PMID: 25938516
Journal: PLoS One
Year: 2015
Reference: PLoS One. 2015 May 4;10(5):e0125753. doi: 10.1371/journal.pone.0125753. eCollection 2015.
Impact factor: 3.234
Publication type: Paper in international publication
Authors: Garcia-Dorado, David, Alburquerque-Bejar, Juan J, Barrabes, Jose A, Inserte, Javier, Agullo, Luis, Rodriguez-Sinovas, Antonio et al.
DOI: 10.1371/journal.pone.0125753

Constrictive Pericarditis: Etiologic Spectrum, Patterns of Clinical Presentation, Prognostic Factors, and Long-term Follow-up.

PMID: 25936614
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2015
Reference: Rev Esp Cardiol (Engl Ed). 2015 Dec;68(12):1092-100. doi: 10.1016/j.rec.2014.12.018. Epub 2015 Apr 27.
Impact factor: 3.792
Publication type: Paper in national publication
Authors: Porta-Sanchez, Andreu, Sagrista-Sauleda, Jaume, Ferreira-Gonzalez, Ignacio, Torrents-Fernandez, Asuncion, Roca-Luque, Ivo, Garcia-Dorado, David et al.
DOI: 10.1016/j.rec.2014.12.018

Time elapsed after contrast injection is crucial to determine infarct transmurality and myocardial functional recovery after an acute myocardial infarction.

PMID: 26024662
Journal: JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
Year: 2015
Reference: J Cardiovasc Magn Reson. 2015 May 30;17:43. doi: 10.1186/s12968-015-0139-8.
Impact factor: 4.556
Publication type: Paper in international publication
Authors: Rodriguez-Palomares, Jose F, Ortiz-Perez, Jose T, Lee, Daniel C, Bucciarelli-Ducci, Chiara, Tejedor, Paula, Bonow, Robert O, Wu, Edwin et al.
DOI: 10.1186/s12968-015-0139-8

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News

The consensus document is the result of multidisciplinary work that takes into account the risks associated with all stages of women's lives and the differences compared to men.

The study, which involved Vall d'Hebron, developed an action plan to efficiently allocate resources to patients most at risk of suffering this complication.

In light of this evidence, hospitals such as Vall d'Hebron have already started to include warnings about environmental pollution in their hospital discharge plans after a myocardial infarction.