About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.
Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.
Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours
PMID: 34850167 Journal: NEURO-ONCOLOGY Year: 2022 Reference: Neuro Oncol. 2022 Jun 1;24(6):997-1007. doi: 10.1093/neuonc/noab274. Impact factor: 12.3 Publication type: Paper in international publication Authors: Doz, Francois, van Tilburg, Cornelis M, Geoerger, Birgit, Hojgaard, Martin, Ora, Ingrid, Boni, Valentina, Capra, Michael, Chisholm, Julia, Chung, Hyun Cheol, DuBois, Steven G et al. DOI: 10.1093/neuonc/noab274
PMID: 35344745 Journal: Cancer Epidemiology Year: 2022 Reference: Cancer Epidemiol. 2022 Jun;78:102145. doi: 10.1016/j.canep.2022.102145. Epub 2022 Mar 25. Impact factor: 2.984 Publication type: Paper in international publication Authors: Pardo-Romaguera, Elena, Segura, Vanessa, Munoz-Lopez, Ana, Galceran-Padros, Jaume, Fernandez-Teijeiro, Ana, Gatta, Gemma, Cruz, O, Benito, A I, Buedo, M I, Calvo, C et al. DOI: 10.1016/j.canep.2022.102145
PMID: 35614316 Journal: BONE MARROW TRANSPLANTATION Year: 2022 Reference: Bone Marrow Transplant. 2022 May 25. pii: 10.1038/s41409-022-01722-6. doi: 10.1038/s41409-022-01722-6. Impact factor: 5.483 Publication type: Letter whit IF Authors: Talarn, Carme, Cid, Joan, Azqueta, Carmen, Valdivia, Elena, Martorell, Lluis, Codinach, Margarita, Marsal, Julia, Mussetti, Alberto, Esquirol, Albert, Trabazo, Maria et al. DOI: 10.1038/s41409-022-01722-6
PMID: 35580896 Journal: International Journal of Laboratory Hematology Year: 2022 Reference: Int J Lab Hematol. 2022 May 17. doi: 10.1111/ijlh.13878. Impact factor: 2.877 Publication type: Letter whit IF Authors: Faneca, Joana, Moreno-Castano, Ana Belen, Diaz-Ricart, Maribel, Escolar, Gines, Garcia, Estefania, Manu-Pereira, Maria Del Mar, Idrizovic, Amira, Matute, Monica, Molina, Angel, Merino, Anna et al. DOI: 10.1111/ijlh.13878
PMID: 34858907 Journal: Frontiers in Pediatrics Year: 2021 Reference: Front Pediatr. 2021 Nov 11;9:761726. doi: 10.3389/fped.2021.761726. eCollection 2021. Impact factor: 3.418 Publication type: Paper in international publication Authors: Gomez-Ganda, Laura, Benitez-Carabante, Maria Isabel, Fernandez-Polo, Aurora, Munoz-Lopez, Marina, Renedo-Miro, Berta, Ariceta, Gema, Diaz De Heredia, Cristina et al. DOI: 10.3389/fped.2021.761726
PMID: 34780709 Journal: LANCET ONCOLOGY Year: 2021 Reference: Lancet Oncol. 2021 Dec;22(12):1764-1776. doi: 10.1016/S1470-2045(21)00536-2. Epub 2021 Nov 12. Impact factor: 41.316 Publication type: Paper in international publication Authors: Fischer, Matthias, Moreno, Lucas, Ziegler, David S, Marshall, Lynley V, Zwaan, C Michel, Irwin, Meredith S, Casanova, Michela, Sabado, Constantino, Wulff, Beate, Stegert, Mario et al. DOI: 10.1016/S1470-2045(21)00536-2
PMID: 34562750 Journal: ESMO Open Year: 2021 Reference: ESMO Open. 2021 Oct;6(5):100250. doi: 10.1016/j.esmoop.2021.100250. Epub 2021 Sep 22. Impact factor: 6.54 Publication type: Paper in international publication Authors: Okpara, C E, He, C, Dutta, L, Casanova, M, Marec-Berard, P, Strauss, S J, Entz-Werle, N, Lervat, C, Gaspar, N, Campbell-Hewson, Q et al. DOI: 10.1016/j.esmoop.2021.100250
PMID: 34462566 Journal: BONE MARROW TRANSPLANTATION Year: 2021 Reference: Bone Marrow Transplant. 2021 Dec;56(12):2956-2963. doi: 10.1038/s41409-021-01449-w. Epub 2021 Aug 31. Impact factor: 5.483 Publication type: Paper in international publication Authors: Diaz-de-Heredia, Cristina, Bresters, Dorine, Faulkner, Lawrence, Yesilipek, Akif, Strahm, Brigitte, Miano, Maurizio, Dalle, Jean-Hugues, Peffault de Latour, Regis, Corbacioglu, Selim et al. DOI: 10.1038/s41409-021-01449-w
PMID: 32869534 Journal: Cancer Medicine Year: 2020 Reference: Cancer Med. 2020 Oct;9(20):7580-7589. doi: 10.1002/cam4.3365. Epub 2020 Sep 1. Impact factor: 3.491 Publication type: Paper in international publication Authors: Terwisscha van Scheltinga, Sheila E J, Wijnen, Marc H W A, Martelli, Helene, Rogers, Timothy, Mandeville, Henry, Gaze, Mark N, McHugh, Keiran, Corradini, Nadege, Orbach, Daniel, Jenney, Meriel et al. DOI: 10.1002/cam4.3365
PMID: 32801295 Journal: Cell Death & Disease Year: 2020 Reference: Cell Death Dis. 2020 Aug 15;11(8):634. doi: 10.1038/s41419-020-02887-y. Impact factor: 6.304 Publication type: Paper in international publication Authors: Alcon, Clara, Manzano-Munoz, Albert, Prada, Estela, Mora, Jaume, Soriano, Aroa, Guillen, Gabriela, Gallego, Soledad, Roma, Josep, Samitier, Josep, Villanueva, Alberto et al. DOI: 10.1038/s41419-020-02887-y
PMID: 32708733 Journal: Cancers Year: 2020 Reference: Cancers (Basel). 2020 Jul 16;12(7). pii: cancers12071922. doi: 10.3390/cancers12071922. Impact factor: 6.126 Publication type: Paper in international publication Authors: Martini, Maurizio, Ruggiero, Antonio, Moreno, Lucas, Sanchez de Toledo, Josep, Gallego, Soledad, Bove, Jordi, Hooker, Jacob M, Segura, Miguel F, Martinez-Saez, Elena, Roma, Josep et al. DOI: 10.3390/cancers12071922
PMID: 32672895 Journal: PEDIATRIC BLOOD & CANCER Year: 2020 Reference: Pediatr Blood Cancer. 2020 Sep;67(9):e28557. doi: 10.1002/pbc.28557. Epub 2020 Jul 16. Impact factor: 2.355 Publication type: Letter whit IF Authors: Fernandez Sanmartin, Manuel, Baragano, Marta, Gorostegui, Maite, Perez-Jaume, Sara, Fernandez-Teijeiro, Ana, Morales La Madrid, Andres, Dapena, Jose Luis, Perez-Alonso, Vanesa, Juan Ribelles, Antonio, Fuster, Jose Luis et al. DOI: 10.1002/pbc.28557
The association, once again, has shown its commitment to oncological research with a donation of €19,197 to the Cancer and Hematological Diseases Group for Children at VHIR.
The prestigious journal The Lancet has published the results of this study, which is the result of more than 20 years of pre-clinical research and 7 years of patient follow-up.
During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.
