About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.
Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.
Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours
PMID: 35393436 Journal: Cell Death Discovery Year: 2022 Reference: Cell Death Discov. 2022 Apr 7;8(1):172. doi: 10.1038/s41420-022-00959-w. Impact factor: 5.241 Publication type: Paper in international publication Authors: Alcon, Clara, Martin, Fernando, Prada, Estela, Mora, Jaume, Soriano, Aroa, Guillen, Gabriela, Gallego, Soledad, Roma, Josep, Samitier, Josep, Villanueva, Alberto et al. DOI: 10.1038/s41420-022-00959-w
PMID: 35289066 Journal: JOURNAL OF THROMBOSIS AND HAEMOSTASIS Year: 2022 Reference: J Thromb Haemost. 2022 Jun;20(6):1390-1399. doi: 10.1111/jth.15699. Epub 2022 Mar 27. Impact factor: 5.824 Publication type: Paper in international publication Authors: Vagace, Jose Manuel, Ruiz-Llobet, Anna, Gassiot, Susanna, Sarrate, Edurne, Zubicaray, Josune, Dapena, Jose Luis, Rives, Susana, Sevilla, Julian, Menarguez Lopez, Angela, Panesso Romero, Melissa et al. DOI: 10.1111/jth.15699
PMID: 35241283 Journal: MEDICINA CLINICA Year: 2022 Reference: Med Clin (Barc). 2022 Feb 28. pii: S0025-7753(22)00055-0. doi: 10.1016/j.medcli.2022.01.009. Impact factor: 1.725 Publication type: Paper in national publication Authors: Galan-Gomez, Victor, Mestre, Carmen, Gonzalez-Vicent, Marta, Pascual, Antonia, Alonso, Laura, Regueiro, Alexandra, Plaza, Mercedes, Perez Hurtado, Jose Maria, Benito, Ana, Fuster, Jose Luis et al. DOI: 10.1016/j.medcli.2022.01.009
PMID: 34781360 Journal: Blood Advances Year: 2022 Reference: Blood Adv. 2022 Mar 8;6(5):1512-1524. doi: 10.1182/bloodadvances.2021005294. Impact factor: 6.799 Publication type: Paper in international publication Authors: Kapoor, Neena, Chiesa, Robert, Boelens, Jaap Jan, Duncan, Christine N, Kuhl, Jorn-Sven, Sevin, Caroline, Jones, Simon A, Amartino, Hernan M, Algeri, Mattia, Bunin, Nancy et al. DOI: 10.1182/bloodadvances.2021005294
PMID: 34395344 Journal: Frontiers in Pediatrics Year: 2021 Reference: Front Pediatr. 2021 Jul 29;9:705179. doi: 10.3389/fped.2021.705179. eCollection 2021. Impact factor: 3.418 Publication type: Paper in international publication Authors: Yaniv, Isaac, Bonig, Halvard, Kuhlen, Michaela, Ansari, Marc, Nava, Tiago, Dalle, Jean-Hugues, Diaz-de-Heredia, Cristina, Trigoso, Eugenia, Falkenberg, Ulrike, Hartmann, Mihaela et al. DOI: 10.3389/fped.2021.705179
PMID: 34385068 Journal: EUROPEAN JOURNAL OF CANCER Year: 2021 Reference: Eur J Cancer. 2021 Sep;155:155-162. doi: 10.1016/j.ejca.2021.07.006. Epub 2021 Aug 9. Impact factor: 9.162 Publication type: Paper in international publication Authors: Mercolini, Federico, Zucchetta, Pietro, Jehanno, Nina, Corradini, Nadege, Van Rijn, Rick R, Rogers, Timothy, Cameron, Alison, Scarzello, Giovanni, Coppadoro, Beatrice, Minard-Colin, Veronique et al. DOI: 10.1016/j.ejca.2021.07.006
PMID: 34343032 Journal: JOURNAL OF CLINICAL ONCOLOGY Year: 2021 Reference: J Clin Oncol. 2021 Sep 20;39(27):2979-2990. doi: 10.1200/JCO.21.00124. Epub 2021 Aug 3. Impact factor: 44.544 Publication type: Letter whit IF Authors: Casanova, Michela, Defachelles, Anne-Sophie, Bogart, Emilie, Calareso, Giuseppina, Gallego Melcon, Soledad, Gatz, Susanne Andrea, Le Deley, Marie-Cecile, McHugh, Kieran, Probst, Alicia, Rocourt, Nathalie et al. DOI: 10.1200/JCO.21.00124
PMID: 34200506 Journal: Journal of Fungi Year: 2021 Reference: J Fungi (Basel). 2021 Jun 7;7(6). pii: jof7060456. doi: 10.3390/jof7060456. Impact factor: 5.816 Publication type: Paper in international publication Authors: Soler-Palacin, Pere, Valle-T-Figueras, Jose Maria, Renedo Miro, Berta, Benitez Carabante, Maria Isabel, Diaz-de-Heredia, Cristina, Vima Bofarull, Jaume, Mendoza-Palomar, Natalia, Martin-Gomez, Maria Teresa et al. DOI: 10.3390/jof7060456
PMID: 32593520 Journal: ANALES DE PEDIATRIA Year: 2020 Reference: An Pediatr (Barc). 2020 Aug;93(2):132-133. doi: 10.1016/j.anpedi.2020.05.002. Epub 2020 Jun 9. Impact factor: 1.313 Publication type: Letter whit IF Authors: Velasco Puyo, Pablo, Riviere, Jacques G, Soler Palacin, Pere, Diaz de Heredia, Cristina, Moreno, Lucas et al. DOI: 10.1016/j.anpedi.2020.05.002
PMID: 32554315 Journal: EUROPEAN JOURNAL OF CANCER Year: 2020 Reference: Eur J Cancer. 2020 Aug;135:89-97. doi: 10.1016/j.ejca.2020.04.031. Epub 2020 Jun 15. Impact factor: 7.275 Publication type: Paper in international publication Authors: Amoroso, Loredana, Castel, Victoria, Bisogno, Gianni, Casanova, Michela, Marquez-Vega, Catalina, Chisholm, Julia C, Doz, Francois, Moreno, Lucas, Ruggiero, Antonio, Gerber, Nicolas U et al. DOI: 10.1016/j.ejca.2020.04.031
PMID: 32558231 Journal: PEDIATRIC BLOOD & CANCER Year: 2020 Reference: Pediatr Blood Cancer. 2020 Oct;67(10):e28351. doi: 10.1002/pbc.28351. Epub 2020 Jun 18. Impact factor: 2.355 Publication type: Paper in international publication Authors: Brennan, Bernadette, Zanetti, Ilaria, De Salvo, Gian Luca, Orbach, Daniel, Gallego, Soledad, Francotte, Nadine, Schifflers, Stefan, Van Noesel, Max, Kelsey, Anna, Casanova, Michela et al. DOI: 10.1002/pbc.28351
PMID: 32523362 Journal: ClinicoEconomics and outcomes research : CEOR Year: 2020 Reference: Clinicoecon Outcomes Res. 2020 May 15;12:253-264. doi: 10.2147/CEOR.S241880. eCollection 2020. Impact factor: 0 Publication type: Paper in international publication Authors: Ribera Santasusana, Josep Maria, de Andres Saldana, Alejandra, Garcia-Munoz, Nuria, Gostkorzewicz, Joana, Martinez Llinas, Diana, Diaz de Heredia, Cristina et al. DOI: 10.2147/CEOR.S241880
The association, once again, has shown its commitment to oncological research with a donation of €19,197 to the Cancer and Hematological Diseases Group for Children at VHIR.
The prestigious journal The Lancet has published the results of this study, which is the result of more than 20 years of pre-clinical research and 7 years of patient follow-up.
During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.
