About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.
Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.
Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours
PMID: 35170748 Journal: ACTA PSYCHIATRICA SCANDINAVICA Year: 2022 Reference: Acta Psychiatr Scand. 2022 Jul;146(1):36-50. doi: 10.1111/acps.13415. Epub 2022 Feb 25. Impact factor: 6.392 Publication type: Paper in international publication Authors: Salagre, Estela, Aedo, Alberto, Salgado-Pineda, Pilar, Montoro Salvatierra, Irene, Sanchez Gistau, Vanessa, Pomarol-Clotet, Edith, Ramos-Quiroga, Josep Antoni, Carvalho, Andre F, Garcia-Rizo, Clemente, Undurraga, Juan et al. DOI: 10.1111/acps.13415
PMID: 34417960 Journal: Clinical & Translational Oncology Year: 2022 Reference: Clin Transl Oncol. 2022 Feb;24(2):388-392. doi: 10.1007/s12094-021-02693-8. Epub 2021 Aug 21. Impact factor: 3.405 Publication type: Paper in international publication Authors: Diaz-de-Heredia, C, Carrasco, E, Uria Oficialdegui, M L, Murillo-Sanjuan, L, Balmana, J, de Pablo Garcia-Cuenca, A, Lorente Guerrero, J et al. DOI: 10.1007/s12094-021-02693-8
PMID: 34807782 Journal: Expert Opinion on Drug Discovery Year: 2022 Reference: Expert Opin Drug Discov. 2022 Feb;17(2):167-179. doi: 10.1080/17460441.2022.2002297. Epub 2021 Nov 22. Impact factor: 6.098 Publication type: Review in international publication Authors: Segura, Miguel F, Soriano, Aroa, Roma, Josep, Piskareva, Olga, Jimenez, Carlos, Boloix, Ariadna, Fletcher, Jamie I, Haber, Michelle, Gray, Juliet C, Cerda-Alberich, Leonor et al. DOI: 10.1080/17460441.2022.2002297
PMID: 34786859 Journal: Small Year: 2022 Reference: Small. 2022 Jan;18(3):e2101959. doi: 10.1002/smll.202101959. Epub 2021 Nov 16. Impact factor: 13.281 Publication type: Paper in international publication Authors: de Toledo, Josep Sanchez, Gallego, Soledad, Veciana, Jaume, Albertazzi, Lorenzo, Segura, Miguel F, Ventosa, Nora, Sala, Santi, Cordoba, Alba, Foradada, Laia, Boloix, Ariadna et al. DOI: 10.1002/smll.202101959
PMID: 34212338 Journal: Clinical & Translational Oncology Year: 2021 Reference: Clin Transl Oncol. 2021 Dec;23(12):2460-2473. doi: 10.1007/s12094-021-02654-1. Epub 2021 Jul 1. Impact factor: 3.405 Publication type: Paper in international publication Authors: Ruano, D, Rubio, P, Verges, R, Valverde, C, Gallego, S, Bernabeu, D, Hindi, N, Mata, C, Marquez, C, Orcajo, J et al. DOI: 10.1007/s12094-021-02654-1
PMID: 34193899 Journal: Scientific Reports Year: 2021 Reference: Sci Rep. 2021 Jun 30;11(1):13553. doi: 10.1038/s41598-021-92747-2. Impact factor: 4.38 Publication type: Paper in international publication Authors: Rizzuto, Valeria, Mencattini, Arianna, Alvarez-Gonzalez, Begona, Di Giuseppe, Davide, Martinelli, Eugenio, Beneitez-Pastor, David, Lopez-Martinez, Maria Jose, Samitier, Josep, Manu-Pereira, Maria Del Mar et al. DOI: 10.1038/s41598-021-92747-2
PMID: 33231901 Journal: Transplant Infectious Disease Year: 2021 Reference: Transpl Infect Dis. 2021 Jun;23(3):e13525. doi: 10.1111/tid.13525. Epub 2020 Dec 7. Impact factor: 2.228 Publication type: Review in international publication Authors: Soques Vallejo, Elena, Roca, Isabel, Navarro, Alexandra, Diaz-de-Heredia, Cristina, Benitez-Carabante, Maria Isabel, Valero Arrese, Lorena et al. DOI: 10.1111/tid.13525
PMID: 34127808 Journal: BONE MARROW TRANSPLANTATION Year: 2021 Reference: Bone Marrow Transplant. 2021 Oct;56(10):2489-2496. doi: 10.1038/s41409-021-01367-x. Epub 2021 Jun 14. Impact factor: 5.483 Publication type: Paper in international publication Authors: Linares, Monica, Ancochea, Agueda, Garcia-Rey, Enric, Garcia-Munoz, Nadia, Medina, Laura, Castillo, Nerea, Carreras, Enric, Villa, Juliana, Querol, Sergio, Valcarcel, David et al. DOI: 10.1038/s41409-021-01367-x
PMID: 32455804 Journal: Cancers Year: 2020 Reference: Cancers (Basel). 2020 May 21;12(5). pii: cancers12051313. doi: 10.3390/cancers12051313. Impact factor: 6.126 Publication type: Review in international publication Authors: Montesinos, Pau, Sobas, Marta, Talarn-Forcadell, Maria Carme, Martinez-Cuadron, David, Escoda, Lourdes, Garcia-Perez, Maria J, Mariz, Jose, Mela-Osorio, Maria J, Fernandez, Isolda, Alonso-Dominguez, Juan M et al. DOI: 10.3390/cancers12051313
PMID: 32421361 Journal: Expert Opinion on Drug Discovery Year: 2020 Reference: Expert Opin Drug Discov. 2020 Aug;15(8):869-872. doi: 10.1080/17460441.2020.1767064. Epub 2020 May 18. Impact factor: 4.887 Publication type: Editorail in international publication Authors: Moreno, Lucas, DuBois, Steven G, Marshall, Lynley V, Fox, Elizabeth, Carceller, Fernando, Pearson, Andrew Dj et al. DOI: 10.1080/17460441.2020.1767064
PMID: 31147440 Journal: HAEMATOLOGICA Year: 2020 Reference: Haematologica. 2020 Jan 31;105(2):338-347. doi: 10.3324/haematol.2018.188151. Print 2020. Impact factor: 7.116 Publication type: Paper in international publication Authors: van Wijk, Richard, Bogdanova, Anna, Manu-Pereira, Maria, Kaestner, Lars, Corrons, Joan-LLuis Vives, Makhro, Asya, Llaudet-Planas, Esther, Hertz, Laura, Petkova-Kirova, Polina, Verhagen, Liesbeth P et al. DOI: 10.3324/haematol.2018.188151
PMID: 32335674 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2020 Reference: J Antimicrob Chemother. 2020 Aug 1;75(8):2264-2271. doi: 10.1093/jac/dkaa149. Impact factor: 5.439 Publication type: Paper in international publication Authors: Mendoza-Palomar, Natalia, Soques, Elena, Benitez-Carabante, Maria Isabel, Gonzalez-Amores, Miriam, Fernandez-Polo, Aurora, Renedo, Berta, Martin, Maria Teresa, Soler-Palacin, Pere, Diaz-de-Heredia, Cristina et al. DOI: 10.1093/jac/dkaa149
The association, once again, has shown its commitment to oncological research with a donation of €19,197 to the Cancer and Hematological Diseases Group for Children at VHIR.
The prestigious journal The Lancet has published the results of this study, which is the result of more than 20 years of pre-clinical research and 7 years of patient follow-up.
During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.
