Skip to main content

Clinical Research/Innovation in Pneumonia & Sepsis (CRIPS)

CRIPS is a research group focusing on severe acute respiratory infections and sepsis. 

The objective is to develop projects on clinical and translational research in hospital-acquired pneumonia, community-acquired pneumonia, and severe viral respiratory infections, such as influenza and COVID-19. CRIPS also develop epidemiological studies focused on risk and prognostic factors for multi-resistant pathogens, validation of ventilator-associated events in ventilated adult and pediatric patients, incorporating artificial intelligence techniques. It also highlights evidence-based medicine (EBM) research, evaluating therapies and prevention strategies and participating in the formulation of clinical practice guidelines, as part of CIBERES and the European Society for Clinical Microbiology and Infections. The EBM research focuses on knowledge translation to get research findings to the point of decision making, providing health-related recommendations, focusing on clinical research and relevance of care. 

CRIPS collaborate on a Local (UIC, IDIAP), National (CIBERES), and International level (CHU Nimes, Uolo University, ISARIC and Pneumo-Inspire Networks).

Publications

Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies.

PMID: 35249794
Journal: Intensive and Critical Care Nursing
Year: 2022
Reference: Intensive Crit Care Nurs. 2022 Jun;70:103227. doi: 10.1016/j.iccn.2022.103227. Epub 2022 Mar 3.
Impact factor: 3.072
Publication type: Paper in international publication
Authors: Blot, Stijn, Ruppe, Etienne, Harbarth, Stephan, Asehnoune, Karim, Poulakou, Garyphalia, Luyt, Charles-Edouard, Rello, Jordi, Klompas, Michael, Depuydt, Pieter, Martin-Loeches, Ignacio et al.
DOI: 10.1016/j.iccn.2022.103227

The COVID-19 vaccination acceptance/hesitancy rate and its determinants among healthcare workers of 91 Countries: A multicenter cross-sectional study.

PMID: 35221837
Journal: EXCLI Journal
Year: 2022
Reference: EXCLI J. 2022 Jan 6;21:93-103. doi: 10.17179/excli2021-4439. eCollection 2022.
Impact factor: 4.068
Publication type: Paper in international publication
Authors: Lefrant, Jean Yves, Zajkowska, Joanna, Rello, Jordi, Kazi, Momin, Taghrir, Mohammad Hossein, Blot, Stijn, Leib, Stephen, Hosseinpour, Parisa, Hosseinpour, Hamidreza, Erfani, Amirhossein et al.
DOI: 10.17179/excli2021-4439

Safety and Efficacy of Devices Delivering Inhaled Antibiotics among Adults with Non-Cystic Fibrosis Bronchiectasis: A Systematic Review and a Network Meta-Analysis.

PMID: 35203878
Journal: Antibiotics-Basel
Year: 2022
Reference: Antibiotics (Basel). 2022 Feb 19;11(2). pii: antibiotics11020275. doi: 10.3390/antibiotics11020275.
Impact factor: 4.639
Publication type: Review in international publication
Authors: Tejada, Sofia, Forero, Carlos G, Gallego, Miguel, Soriano, Joan B, Cardinal-Fernandez, Pablo A, Ehrmann, Stephan, Rello, Jordi, Ramirez-Estrada, Sergio et al.
DOI: 10.3390/antibiotics11020275

COVID-19 cutaneous manifestations in pediatric patients: 24 MIS-C and 6 Kawasaki disease cases.

PMID: 34807486
Journal: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Year: 2022
Reference: J Eur Acad Dermatol Venereol. 2022 Mar;36(3):e180-e182. doi: 10.1111/jdv.17828. Epub 2021 Dec 1.
Impact factor: 6.166
Publication type: Letter or abstract
Authors: Tammaro, A, Karim, D, Adebanjo, G A R, Parisella, F R, Chello, C, Salih, A F, Rello, J et al.
DOI: 10.1111/jdv.17828

What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol.

PMID: 33692181
Journal: BMJ Open
Year: 2021
Reference: BMJ Open. 2021 Mar 10;11(3):e043887. doi: 10.1136/bmjopen-2020-043887.
Impact factor: 2.692
Publication type: Paper in international publication
Authors: Palmieri, Carlo, Munblit, Daniel, Holter, Jan Cato, Kildal, Anders Benjamin, Reyes, Luis Felipe, Russell, Clark D, Ho, Antonia, Turtle, Lance, Drake, Thomas M, Beltrame, Anna et al.
DOI: 10.1136/bmjopen-2020-043887

Short-Acting Sedative-Analgesic Drugs Protect Against Development of Ventilator-Associated Events in Children: Secondary Analysis of the EUVAE Study.

PMID: 33688086
Journal: Respiratory Care
Year: 2021
Reference: Respir Care. 2021 May;66(5):798-805. doi: 10.4187/respcare.08597. Epub 2021 Mar 9.
Impact factor: 2.258
Publication type: Paper in international publication
Authors: Rello, Jordi, Lagunes, Leonel, Serrano-Megias, Marta, Ramirez-Estrada, Sergio, Pena-Lopez, Yolanda et al.
DOI: 10.4187/respcare.08597

Performance of Existing Definitions and Tests for the Diagnosis of Invasive Fungal Diseases other than Invasive Candidiasis and Invasive Aspergillosis in Critically Ill, Adult Patients: A Systematic Review with Qualitative Evidence Synthesis.

PMID: 33670864
Journal: Journal of Fungi
Year: 2021
Reference: J Fungi (Basel). 2021 Feb 28;7(3). pii: jof7030176. doi: 10.3390/jof7030176.
Impact factor: 5.816
Publication type: Review in international publication
Authors: Zuccaro, Valentina, Giacobbe, Daniele R, Cortegiani, Andrea, Karaiskos, Ilias, Mercier, Toine, Tejada, Sofia, Peghin, Maddalena, Grecchi, Cecilia, Rebuffi, Chiara, Asperges, Erika et al.
DOI: 10.3390/jof7030176

Percutaneous atrioseptostomy for left ventricular unloading in pediatric patients in cardiogenic shock on venoarterial ECMO support.

PMID: 33632636
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2021
Reference: Rev Esp Cardiol. 2021 Aug;74(8):710-712. doi: 10.1016/j.rec.2021.01.010. Epub 2021 Feb 23.
Impact factor: 4.753
Publication type: Letter whit IF
Authors: Dolader, Paola, Betrian Blasco, Pedro, Balcells, Joan, Izquierdo-Blasco, Jaume, Gran, Ferran, Marti Aguasca, Gerard et al.
DOI: 10.1016/j.rec.2021.01.010

Planning for the assistance of critically ill patients in a Pandemic Situation: The experience of Vall d'Hebron University Hospital.

PMID: 33010961
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2020
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2020 Sep 8. pii: S0213-005X(20)30272-X. doi: 10.1016/j.eimc.2020.08.007.
Impact factor: 1.654
Publication type: Paper in national publication
Authors: Ferrer, Ricard, Baguena, Marcelino, Balcells, Joan, Baneras, Jordi, Biarnes, Alfons, de Nadal, Miriam, Gracia, Rosa Maria, Martinez, Jesus, Nuvials, Xavier, Riera, Jordi et al.
DOI: 10.1016/j.eimc.2020.08.007

Steroids and COVID-19: We Need a Precision Approach, Not One Size Fits All.

PMID: 32936438
Journal: Infectious Diseases and Therapy
Year: 2020
Reference: Infect Dis Ther. 2020 Dec;9(4):701-705. doi: 10.1007/s40121-020-00338-x. Epub 2020 Sep 16.
Impact factor: 4.307
Publication type: Editorail in international publication
Authors: Waterer, Grant W, Rello, Jordi et al.
DOI: 10.1007/s40121-020-00338-x

Evaluation of the quality of evidence supporting guideline recommendations for the nutritional management of critically ill adults.

PMID: 32859308
Journal: Clinical nutrition ESPEN
Year: 2020
Reference: Clin Nutr ESPEN. 2020 Oct;39:144-149. doi: 10.1016/j.clnesp.2020.07.004. Epub 2020 Aug 5.
Impact factor: 0
Publication type: Paper in international publication
Authors: Xu, Elena, Tejada, Sofia, Sole-Lleonart, Candela, Campogiani, Laura, Valenzuela-Sanchez, Francisco, Koulenti, Despoina, Rello, Jordi et al.
DOI: 10.1016/j.clnesp.2020.07.004

Oversedation Zero as a tool for comfort, safety and intensive care unit management.

PMID: 31733988
Journal: Medicina Intensiva
Year: 2020
Reference: Med Intensiva. 2020 May;44(4):239-247. doi: 10.1016/j.medin.2019.09.010. Epub 2019 Nov 14.
Impact factor: 2.363
Publication type: Paper in national publication
Authors: Gomez, Francisco Jose Guerrero, Jambrina, Carlos Chamorro, Vivien, Isabel Cherta, Saez, Frutos Del Nogal, Cobo, Jose Luis Escalante, Alfaro, Claudio Garcia, Sanchez, Francisco Javier Gil, Vich, Carolina Gimenez-Esparza, Sanz, Victor Gonzalez, Arenas, Paloma Gonzalez et al.
DOI: 10.1016/j.medin.2019.09.010

Perceived differences between intensivists and infectious diseases consultants facing antimicrobial resistance: a global cross-sectional survey.

PMID: 30900056
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2019
Reference: Eur J Clin Microbiol Infect Dis. 2019 Jul;38(7):1235-1240. doi: 10.1007/s10096-019-03530-1. Epub 2019 Mar 21.
Impact factor: 2.591
Publication type: Paper in international publication
Authors: Alp, Emine, Rello, Jordi, Kalwaje Eshwara, Vandana, Conway-Morris, Andrew, Lagunes, Leonel, Alves, Joana, Mer, Mervyn, Zhang, Zhongheng et al.
DOI: 10.1007/s10096-019-03530-1

Ten tips for the intensive care management of transplanted lung patients.

PMID: 30840123
Journal: INTENSIVE CARE MEDICINE
Year: 2019
Reference: Intensive Care Med. 2019 Mar;45(3):371-373. doi: 10.1007/s00134-019-05578-1. Epub 2019 Mar 6.
Impact factor: 18.967
Publication type: Editorail in international publication
Authors: Welte, Tobias, Ingels, Catherine, Rello, Jordi et al.
DOI: 10.1007/s00134-019-05578-1

Correction to: The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: What is the current evidence?

PMID: 30820839
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2019
Reference: Eur J Clin Microbiol Infect Dis. 2019 Apr;38(4):649. doi: 10.1007/s10096-019-03518-x.
Impact factor: 2.591
Publication type: Letter or abstract
Authors: Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey, Rello, Jordi et al.
DOI: 10.1007/s10096-019-03518-x

Ventilator-Associated Pneumonia due to Drug-Resistant Acinetobacter baumannii: Risk Factors and Mortality Relation with Resistance Profiles, and Independent Predictors of In-Hospital Mortality.

PMID: 30781896
Journal: Medicina-Lithuania
Year: 2019
Reference: Medicina (Kaunas). 2019 Feb 13;55(2). pii: medicina55020049. doi: 10.3390/medicina55020049.
Impact factor: 1.467
Publication type: Paper in international publication
Authors: Adukauskiene, Dalia, Rello, Jordi, Ciginskiene, Ausra, Dambrauskiene, Asta et al.
DOI: 10.3390/medicina55020049

Patients with New York Heart Association class III heart failure may benefit with high flow nasal cannula supportive therapy: High flow nasal cannula in heart failure.

PMID: 23602035
Journal: JOURNAL OF CRITICAL CARE
Year: 2013
Reference: J Crit Care. 2013 Oct;28(5):741-6. doi: 10.1016/j.jcrc.2013.02.007. Epub 2013 Apr 16.
Impact factor: 2.498
Publication type: Paper in international publication
Authors: Roca, Oriol, Perez-Teran, Purificacion, Masclans, Joan R, Perez, Lourdes, Galve, Enrique, Evangelista, Arturo, Rello, Jordi et al.
DOI: 10.1016/j.jcrc.2013.02.007

Epidemiology, Clinical Features, and Prognosis of Elderly Adults with Severe Forms of Influenza A (H1N1).

PMID: 23496351
Journal: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Year: 2013
Reference: J Am Geriatr Soc. 2013 Mar;61(3):350-6.
Impact factor: 3.978
Publication type: Paper in international publication
Authors: Gutierrez-Pizarraya, Antonio, Marquez, Juan A, Zaragoza, Rafael, Granada, Rosa, Ruiz-Santana, Sergio, Rello, Jordi, Rodriguez, Alejandro, Garnacho-Montero, Jose et al.
DOI: 10.1111/jgs.12152

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012.

PMID: 23353941
Journal: CRITICAL CARE MEDICINE
Year: 2013
Reference: Crit Care Med. 2013 Feb;41(2):580-637. doi: 10.1097/CCM.0b013e31827e83af.
Impact factor: 6.124
Publication type: Paper in international publication
Authors: Resende, Ederlon, Rhodes, Andrew, Annane, Djillali, Gerlach, Herwig, Opal, Steven M, Sevransky, Jonathan E, Sprung, Charles L, Douglas, Ivor S, Jaeschke, Roman, Osborn, Tiffany M et al.
DOI: 10.1097/CCM.0b013e31827e83af

The impact of lung transplantation on ICU personnel.

PMID: 23398845
Journal: Medicina Intensiva
Year: 2013
Reference: Med Intensiva. 2013 Apr;37(3):206-8. doi: 10.1016/j.medin.2012.12.003. Epub 2013 Feb 9.
Impact factor: 1.323
Publication type: Paper in national publication
Authors: Rello, J, Masnou, N et al.
DOI: 10.1016/j.medin.2012.12.003

Antibiotic dosing in multiple organ dysfunction syndrome.

PMID: 21540219
Journal: CHEST
Year: 2011
Reference: Chest. 2011 May;139(5):1210-20.
Impact factor: 6.519
Publication type: Paper in international publication
Authors: Lipman, Jeffrey, Rello, Jordi, Roberts, Jason A, Ulldemolins, Marta et al.
DOI: 10.1378/chest.10-2371

New Treatment Options for Infections Caused by Multiresistant Strains of Pseudomonas aeruginosa and Other Nonfermenting Gram-Negative Bacilli.

PMID: 21506051
Journal: SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2011
Reference: Semin Respir Crit Care Med. 2011 Apr;32(2):151-8. Epub 2011 Apr 19.
Impact factor: 2.492
Publication type: Review in international publication
Authors: Gattarello, Simone, Rello, Jordi, Sanchez, Anna et al.
DOI: 10.1055/s-0031-1275527

[Incidence of central line-associated bloodstream infection in an intensive care unit.]

PMID: 21507738
Journal: ANALES DE PEDIATRIA
Year: 2011
Reference: An Pediatr (Barc). 2011 Sep;75(3):188-93. Epub 2011 Apr 19.
Impact factor: 0.57
Publication type: Paper in national publication
Authors: , , , , , , et al.
DOI: 10.1016/j.anpedi.2011.03.002

Impact of non-exacerbated COPD on mortality in critically ill patients.

PMID: 21393392
Journal: CHEST
Year: 2011
Reference: Chest. 2011 Jun;139(6):1354-60. Epub 2011 Mar 10.
Impact factor: 6.519
Publication type: Paper in international publication
Authors: , , , , , , , , et al.
DOI: 10.1378/chest.10-2439

Blog

News

A study, in which Vall d'Hebron has participated, has analysed all the interventions of this type carried out between 2006 and 2020.

The work of the multinational team, which has reviewed the records of more than one million patients who have received a new organ, has found significant differences between women and men

The scientific review reports that changes in the respiratory system flora due to pollution increase the risk of suffering a hospital infection caused by multidrug-resistant organisms.