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Liver Diseases

The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.

Publications

A year living with SARS-CoV-2: an epidemiological overview of viral lineage circulation by whole-genome sequencing in Barcelona city (Catalonia, Spain).

PMID: 34842496
Journal: Emerging Microbes & Infections
Year: 2022
Reference: Emerg Microbes Infect. 2022 Dec;11(1):172-181. doi: 10.1080/22221751.2021.2011617.
Impact factor:
Publication type: Paper in international publication
Authors: Andres, Cristina; Anton, Andres; Blanco-Grau, Albert; Borras-Bermejo, Blanca; Campins-Marti, Magda; Campos, Carolina; Castillo, Carla; Codina, Maria Gema; Colomer-Castell, Sergi; Esperalba, Juliana et al.
DOI: 10.1080/22221751.2021.2011617

Characterization of the liver immune microenvironment in liver biopsies from patients with chronic HBV infection.

PMID: 34950863
Journal: JHEP Reports
Year: 2022
Reference: JHEP Rep. 2021 Oct 24;4(1):100388. doi: 10.1016/j.jhepr.2021.100388. eCollection 2022 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Aggarwal, Abhishek; Bhardwaj, Neeru; Bui, Nam; Buti, Maria; Chan, Henry Ly; Chen, Diana; Diehl, Lauri; Feierbach, Becket; Fletcher, Simon P; Gaggar, Anuj et al.
DOI: 10.1016/j.jhepr.2021.100388

Population screening for liver fibrosis: towards early diagnosis and intervention for chronic liver diseases.

PMID: 34537988
Journal: HEPATOLOGY
Year: 2022
Reference: Hepatology. 2022 Jan;75(1):219-228. doi: 10.1002/hep.32163. Epub 2021 Dec 10.
Impact factor:
Publication type: Review in international publication
Authors: Allen, Alina M; Augustin, Salvador; Caballeria, Llorenc; Castera, Laurent; de Knegt, Robert J; de Koning, Harry J; Diaz, M feminine Alba; Fabrellas, Nuria; Garcia-Retortillo, Montserrat; Gines, Pere et al.
DOI: 10.1002/hep.32163

The frequency of defective genomes in Omicron differs from that of the Alpha, Beta and Delta variants.

PMID: 36581627
Journal: Scientific Reports
Year: 2022
Reference: Sci Rep. 2022 Dec 29;12(1):22571. doi: 10.1038/s41598-022-24918-8.
Impact factor:
Publication type: Paper in international publication
Authors: Adombi, Caroline Melanie; Andres, Cristina; Anton, Andres; Borras, Blanca; Campos, Carolina; Codina, Maria Gema; Colomer-Castell, Sergi; Esperalba, Juliana; Esteban, Juan Ignacio; Garcia-Cehic, Damir et al.
DOI: 10.1038/s41598-022-24918-8

Study of Quasispecies Complexity and Liver Damage Progression after Liver Transplantation in Hepatitis C Virus Infected Patients.

PMID: 34828337
Journal: Genes
Year: 2021
Reference: Genes (Basel). 2021 Oct 28;12(11). pii: genes12111731. doi: 10.3390/genes12111731.
Impact factor: 4.096
Publication type: Paper in international publication
Authors: Bilbao, Itxarone, Quer, Josep, Esteban, Juan Ignacio, Perales, Celia, Llorens-Revull, Meritxell, Gregori, Josep, Dopazo, Cristina, Rodriguez-Frias, Francisco, Garcia-Cehic, Damir, Soria, Maria Eugenia et al.
DOI: 10.3390/genes12111731

A novel model of care for simplified testing of HBV in African communities during the COVID-19 pandemic in Spain.

PMID: 34433852
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Aug 25;11(1):17063. doi: 10.1038/s41598-021-96350-3.
Impact factor: 4.38
Publication type: Paper in international publication
Authors: Picchio, Camila A, Nomah, Daniel K, Araujo, Silvia G, Rando-Segura, Ariadna, Fernandez, Emma, Buti, Maria, Rodriguez-Tajes, Sergio, Lens, Sabela, Rodriguez-Frias, Francisco, Lazarus, Jeffrey V et al.
DOI: 10.1038/s41598-021-96350-3

Host-dependent editing of SARS-CoV-2 in COVID-19 patients.

PMID: 34402744
Journal: Emerging Microbes & Infections
Year: 2021
Reference: Emerg Microbes Infect. 2021 Dec;10(1):1777-1789. doi: 10.1080/22221751.2021.1969868.
Impact factor: 7.163
Publication type: Paper in international publication
Authors: Quer, Josep, Anton, Andres, Rodriguez-Frias, Francisco, Esteban, Juan Ignacio, Gregori, Josep, Cortese, Maria Francesca, Pinana, Maria, Campos, Carolina, Garcia-Cehic, Damir, Andres, Cristina et al.
DOI: 10.1080/22221751.2021.1969868

Outcomes and potential surrogate markers for future clinical trials of non-alcoholic steatohepatitis cirrhosis.

PMID: 34242466
Journal: LIVER INTERNATIONAL
Year: 2021
Reference: Liver Int. 2021 Sep;41(9):1999-2008. doi: 10.1111/liv.15013. Epub 2021 Jul 21.
Impact factor: 5.828
Publication type: Review in international publication
Authors: Rivera-Esteban, Jesus, Armandi, Angelo, Augustin, Salvador, Bugianesi, Elisabetta et al.
DOI: 10.1111/liv.15013

Transient elastography in direct acting antiviral era. Relation between liver stiffness measurement after sustained virological response and histology.

PMID: 31816146
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2020
Reference: J Viral Hepat. 2020 Apr;27(4):453-455. doi: 10.1111/jvh.13245. Epub 2019 Dec 18.
Impact factor: 3.561
Publication type: Paper in international publication
Authors: Martinez-Camprecios, Joan, Bonis Puig, Sara, Pons Delgado, Monica, Salcedo Allende, Maria Teresa, Minguez Rosique, Beatriz, Genesca Ferrer, Joan et al.
DOI: 10.1111/jvh.13245

Unexpected long-lasting anti-HEV IgM positivity: Is HEV antigen a better serological marker for hepatitis E infection diagnosis?

PMID: 32106351
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2020
Reference: J Viral Hepat. 2020 Jul;27(7):747-753. doi: 10.1111/jvh.13285. Epub 2020 Mar 11.
Impact factor: 3.561
Publication type: Paper in international publication
Authors: Riveiro-Barciela, Mar, Rando-Segura, Ariadna, Barreira-Diaz, Ana, Bes, Marta, Ruzo, Sofia P, Piron, Maria, Quer, Josep, Sauleda, Silvia, Rodriguez-Frias, Francisco, Esteban, Rafael et al.
DOI: 10.1111/jvh.13285

Optimal management of chronic hepatitis B patients receiving nucleos(t)ide analogues.

PMID: 32077604
Journal: LIVER INTERNATIONAL
Year: 2020
Reference: Liver Int. 2020 Feb;40 Suppl 1:15-21. doi: 10.1111/liv.14367.
Impact factor: 5.175
Publication type: Review in international publication
Authors: Buti, Maria, Roade, Luisa, Riveiro-Barciela, Mar, Esteban, Rafael et al.
DOI: 10.1111/liv.14367

Role of Biomarkers in Guiding Cure of Viral Hepatitis B.

PMID: 31805583
Journal: SEMINARS IN LIVER DISEASE
Year: 2020
Reference: Semin Liver Dis. 2020 Feb;40(1):49-60. doi: 10.1055/s-0039-3401031. Epub 2019 Dec 5.
Impact factor: 4.457
Publication type: Review in international publication
Authors: Buti, Maria, Riveiro-Barciela, Mar, Rodriguez-Frias, Francisco, Tabernero, David, Esteban, Rafael et al.
DOI: 10.1055/s-0039-3401031

Blog

News

The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.

On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.

Estudi sobre els patrons de consum habitual de l'alcohol en població jove

Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.

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