About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 34758113 Journal: HEPATOLOGY Year: 2022 Reference: Hepatology. 2022 Feb;75(2):501-502. doi: 10.1002/hep.32227. Epub 2021 Dec 18. Impact factor: Publication type: Letter or abstract Authors: Buti, Maria; Cortese, Maria Francesca; Rando-Segura, Ariadna; Rodriguez-Frias, Francisco; Tabernero, David et al. DOI: 10.1002/hep.32227
PMID: 34606915 Journal: JOURNAL OF HEPATOLOGY Year: 2022 Reference: J Hepatol. 2022 Feb;76(2):311-318. doi: 10.1016/j.jhep.2021.09.025. Epub 2021 Oct 2. Impact factor: Publication type: Paper in international publication Authors: Ahn, Sang Bong; Berg, Thomas; Buti, Maria; Calleja, Jose Luis; Cho, Yong Kyun; Dalekos, George N; Goulis, John; Idilman, Ramazan; Jang, Eun Sun; Jang, Myoung-Jin et al. DOI: 10.1016/j.jhep.2021.09.025
PMID: 33493697 Journal: Clinical Gastroenterology and Hepatology Year: 2022 Reference: Clin Gastroenterol Hepatol. 2022 Feb;20(2):438-446. doi: 10.1016/j.cgh.2021.01.026. Epub 2021 Jan 22. Impact factor: Publication type: Paper in international publication Authors: Bourliere, Marc; Buti, Maria; Chokkalingam, Anand; Colombo, Massimo; Esteban, Rafael; Gaggar, Anuj; Henry, Linda; Mangia, Alessandra; Manns, Michael; Muir, Andrew et al. DOI: 10.1016/j.cgh.2021.01.026
PMID: 33516950 Journal: Clinical Gastroenterology and Hepatology Year: 2022 Reference: Clin Gastroenterol Hepatol. 2022 Feb;20(2):e289-e297. doi: 10.1016/j.cgh.2021.01.042. Epub 2021 Jan 28. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan Jg; Altamirano, Jose; Arab, Juan Pablo; Arrese, Marco; Bataller, Ramon; Bosques-Padilla, Francisco; Brown, Robert S Jr; Cabezas, Joaquin; Dhanda, Ashwin; Garcia-Tsao, Guadalupe et al. DOI: 10.1016/j.cgh.2021.01.042
PMID: 32360825 Journal: Clinical Gastroenterology and Hepatology Year: 2021 Reference: Clin Gastroenterol Hepatol. 2021 Jan;19(1):46-60.e8. doi: 10.1016/j.cgh.2020.04.045. Epub 2020 Apr 29. Impact factor: Publication type: Paper in international publication Authors: Ahn, Sang Hoon; Alidjinou, Enagnon K; Atsukawa, Masanori; Bocket, Laurence; Brunetto, Maurizia R; Buti, Maria; Carey, Ivana; Caviglia, Gian Paolo; Chen, En-Qiang; Cornberg, Markus et al. DOI: 10.1016/j.cgh.2020.04.045
PMID: 33758887 Journal: Year: 2021 Reference: medRxiv. 2021 Mar 12:2021.03.07.21252875. doi: 10.1101/2021.03.07.21252875. Preprint. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Alarcon-Riquelme, Marta E; Amitano, Sara; Asselta, Rosanna; Banales, Jesus; Bernardo, David; Bouysran, Youssef; Bujanda, Luis; Buti, Maria; Butler-Laporte, Guillaume; Cordioli, Mattia et al. DOI: 10.1101/2021.03.07.21252875
PMID: 35698954 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2021 Reference: Arch Bronconeumol. 2021 Jul;57(7):479-489. doi: 10.1016/j.arbr.2021.03.015. Impact factor: 4.872 Publication type: Paper in international publication Authors: Ojanguren, Amaia, Santamaria, Maite, Milla-Collado, Lucia, Fraile, Carlos, Gatius-Caldero, Sonia, Puy, Sara, Boldo, Alba, Gomez-Olles, Susana, Boada-Perez, Meritxell, Esquinas, Cristina et al. DOI: 10.1016/j.arbr.2021.03.015
PMID: 34597274 Journal: JOURNAL OF CLINICAL INVESTIGATION Year: 2021 Reference: J Clin Invest. 2021 Dec 1;131(23). pii: 152386. doi: 10.1172/JCI152386. Impact factor: 14.808 Publication type: Paper in international publication Authors: O'Byrne, Sheila M, Nakanishi, Tomoko, Pigazzini, Sara, Degenhardt, Frauke, Cordioli, Mattia, Butler-Laporte, Guillaume, Nafria-Jimenez, Beatriz, Hov, Johannes R, Migeotte, Isabelle, Renieri, Alessandra et al. DOI: 10.1172/JCI152386
PMID: 32681987 Journal: Nanomedicine-Nanotechnology Biology and Medicine Year: 2020 Reference: Nanomedicine. 2020 Oct;29:102267. doi: 10.1016/j.nano.2020.102267. Epub 2020 Jul 15. Impact factor: 5.182 Publication type: Paper in international publication Authors: Hide, Diana, Gil, Mar, Andrade, Fernanda, Rafael, Diana, Raurell, Imma, Bravo, Miren, Barbera, Aurora, Gracia-Sancho, Jordi, Vargas, Victor, Augustin, Salvador et al. DOI: 10.1016/j.nano.2020.102267
PMID: 32673741 Journal: JOURNAL OF HEPATOLOGY Year: 2020 Reference: J Hepatol. 2020 Oct;73(4):842-854. doi: 10.1016/j.jhep.2020.06.013. Epub 2020 Jul 13. Impact factor: 20.582 Publication type: Paper in international publication Authors: Elsharkawy, Ahmed, Fernandez, Javier, Papp, Maria, Caraceni, Paolo, Laleman, Wim, Gambino, Carmine, Giovo, Ilaria, Uschner, Frank Erhard, Jimenez, Cesar, Mookerjee, Rajeshwar et al. DOI: 10.1016/j.jhep.2020.06.013
PMID: 32558485 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2020 Reference: N Engl J Med. 2020 Oct 15;383(16):1522-1534. doi: 10.1056/NEJMoa2020283. Epub 2020 Jun 17. Impact factor: 74.699 Publication type: Paper in international publication Authors: My, Ilaria, Ellinghaus, David, Degenhardt, Frauke, Bujanda, Luis, Buti, Maria, Albillos, Agustin, Invernizzi, Pietro, Fernandez, Javier, Prati, Daniele, Baselli, Guido et al. DOI: 10.1056/NEJMoa2020283
PMID: 32523313 Journal: WORLD JOURNAL OF GASTROENTEROLOGY Year: 2020 Reference: World J Gastroenterol. 2020 May 28;26(20):2584-2598. doi: 10.3748/wjg.v26.i20.2584. Impact factor: 3.665 Publication type: Paper in international publication Authors: Rodriguez-Frias, Francisco, Buti, Maria, Esteban, Rafael, Yll, Marcal, Cortese, Maria Francesca, Guerrero-Murillo, Mercedes, Orriols, Gerard, Gregori, Josep, Casillas, Rosario, Gonzalez, Carolina et al. DOI: 10.3748/wjg.v26.i20.2584
The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.
Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.
