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Liver Diseases

The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.

Publications

Editorial: Multidisciplinary management of cancer patients with immune-related adverse events from checkpoint inhibitors.

PMID: 36687413
Journal: Frontiers in Medicine
Year: 2022
Reference: Front Med (Lausanne). 2023 Jan 5;9:1104382. doi: 10.3389/fmed.2022.1104382. eCollection 2022.
Impact factor:
Publication type: Editorail in international publication
Authors: Felip, Enriqueta; Riveiro-Barciela, Mar; Suarez-Almazor, Maria E et al.
DOI: 10.3389/fmed.2022.1104382

Monitoring progress towards elimination of hepatitis B and C in the EU/EEA.

PMID: 36962761
Journal: PLOS global public health
Year: 2022
Reference: PLOS Glob Public Health. 2022 Aug 17;2(8):e0000841. doi: 10.1371/journal.pgph.0000841. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Axelsson, Maria; Buti, Maria; Diaz, Asuncion; Duffell, Erika; Fursa, Olga; Hendrickx, Greet; James, Cary; Klavs, Irena; Korenjak, Marko; Maticic, Mojca et al.
DOI: 10.1371/journal.pgph.0000841

Radiography-based triage for COVID-19 in the Emergency Department in a Spanish cohort of patients.

PMID: 35702721
Journal: Medicina clinica (English ed.)
Year: 2022
Reference: Med Clin (Engl Ed). 2022 May 27;158(10):466-471. doi: 10.1016/j.medcle.2021.05.021. Epub 2022 Jun 9.
Impact factor:
Publication type: Paper in international publication
Authors: Arranz-Betegon, Maria; Canas-Ruano, Esperanza; Domingo-Baldrich, Eva; Fernandez-Codina, Andreu; Garcia-Vives, Eloi; Gil-Vila, Albert; Llaneras-Artigues, Jordi; Meza, Beatriz; Michelena, Xabier; Orozco-Galvez, Olimpia et al.
DOI: 10.1016/j.medcle.2021.05.021

Population screening for liver fibrosis: towards early diagnosis and intervention for chronic liver diseases.

PMID: 34537988
Journal: HEPATOLOGY
Year: 2022
Reference: Hepatology. 2022 Jan;75(1):219-228. doi: 10.1002/hep.32163. Epub 2021 Dec 10.
Impact factor: 17.425
Publication type: Review in international publication
Authors: Hartmann, Phillipp; Gines, Pere; Castera, Laurent; Lammert, Frank; Graupera, Isabel; Serra-Burriel, Miquel; Allen, Alina M; Wong, Vincent Wai-Sun; de Knegt, Robert J; Grgurevic, Ivica et al.
DOI: 10.1002/hep.32163

Partial restoration of immune response in Hepatitis C patients after viral clearance by direct-acting antiviral therapy.

PMID: 34242330
Journal: PLoS One
Year: 2021
Reference: PLoS One. 2021 Jul 9;16(7):e0254243. doi: 10.1371/journal.pone.0254243. eCollection 2021.
Impact factor: 3.24
Publication type: Paper in international publication
Authors: Llorens-Revull, Meritxell, Costafreda, Maria Isabel, Rico, Angie, Guerrero-Murillo, Mercedes, Soria, Maria Eugenia, Piriz-Ruzo, Sofia, Vargas-Accarino, Elena, Gabriel-Medina, Pablo, Rodriguez-Frias, Francisco, Riveiro-Barciela, Mar et al.
DOI: 10.1371/journal.pone.0254243

One-quarter of chronic hepatitis D patients reach HDV-RNA decline or undetectability during the natural course of the disease.

PMID: 34181772
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2021
Reference: Aliment Pharmacol Ther. 2021 Aug;54(4):462-469. doi: 10.1111/apt.16485. Epub 2021 Jun 28.
Impact factor: 8.171
Publication type: Paper in international publication
Authors: Roade, Luisa, Palom, Adriana, Sopena, Sara, Riveiro-Barciela, Mar, Carvalho-Gomes, Angela, Madejon, Antonio, Rodriguez-Tajes, Sergio, Lens, Sabela, Berenguer-Hayme, Marina, Rodriguez-Frias, Francisco et al.
DOI: 10.1111/apt.16485

Low seroprevalence of SARS-CoV-2 antibodies in a liver transplant cohort.

PMID: 34121244
Journal: TRANSPLANT INTERNATIONAL
Year: 2021
Reference: Transpl Int. 2021 Oct;34(10):1908-1913. doi: 10.1111/tri.13946. Epub 2021 Jul 27.
Impact factor: 3.782
Publication type: Paper in international publication
Authors: Campos-Varela, Isabel, Len, Oscar, Villagrasa, Ares, Marquez-Algaba, Ester, Esperalba, Juliana, Dopazo, Cristina, Los-Arcos, Ibai, Anton, Andres, Castells, Lluis et al.
DOI: 10.1111/tri.13946

The role of liver steatosis as measured with transient elastography and transaminases on hard clinical outcomes in patients with COVID-19.

PMID: 34104210
Journal: Therapeutic Advances in Gastroenterology
Year: 2021
Reference: Therap Adv Gastroenterol. 2021 May 30;14:17562848211016567. doi: 10.1177/17562848211016567. eCollection 2021.
Impact factor: 4.409
Publication type: Paper in international publication
Authors: Campos-Varela, Isabel, Villagrasa, Ares, Simon-Talero, Macarena, Riveiro-Barciela, Mar, Ventura-Cots, Meritxell, Aguilera-Castro, Lara, Alvarez-Lopez, Patricia, Nordahl, Emilie A, Rivera-Esteban, Jesus M, Romero, Alba et al.
DOI: 10.1177/17562848211016567

Nursing care of patients with cirrhosis.

PMID: 31944340
Journal: HEPATOLOGY
Year: 2020
Reference: Hepatology. 2020 Mar;71(3):1106-1116. doi: 10.1002/hep.31117.
Impact factor: 14.679
Publication type: Review in international publication
Authors: Fabrellas, Nuria, Carol, Marta, Palacio, Ester, Aban, Marites, Lanzillotti, Tommaso, Nicolao, Gea, Gines, Pere, Chiappa, Maria Teresa, Esnault, Vanessa, Graf-Dirmeier, Sabine et al.
DOI: 10.1002/hep.31117

Editorial: rapid disease progression in hepatitis delta-can we turn the tide? Authors' reply.

PMID: 31850577
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2020
Reference: Aliment Pharmacol Ther. 2020 Jan;51(1):174-175. doi: 10.1111/apt.15558.
Impact factor: 7.515
Publication type: Editorail in international publication
Authors: Palom, Adriana, Riveiro-Barciela, Mar, Buti, Maria et al.
DOI: 10.1111/apt.15558

Safety of two different doses of simvastatin plus rifaximin in decompensated cirrhosis (LIVERHOPE-SAFETY): a randomised, double-blind, placebo-controlled, phase 2 trial.

PMID: 31607677
Journal: Lancet Gastroenterology & Hepatology
Year: 2020
Reference: Lancet Gastroenterol Hepatol. 2020 Jan;5(1):31-41. doi: 10.1016/S2468-1253(19)30320-6. Epub 2019 Oct 10.
Impact factor: 14.789
Publication type: Paper in international publication
Authors: Jimenez, Cesar, Pose, Elisa, Napoleone, Laura, Amin, Ahmed, Campion, Daniela, Sola, Elsa, Uschner, Frank Erhard, de Wit, Koos, Zaccherini, Giacomo, Alessandria, Carlo et al.
DOI: 10.1016/S2468-1253(19)30320-6

Long-term clinical outcomes in patients with chronic hepatitis delta: the role of persistent viraemia.

PMID: 31721254
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2020
Reference: Aliment Pharmacol Ther. 2020 Jan;51(1):158-166. doi: 10.1111/apt.15521. Epub 2019 Nov 13.
Impact factor: 7.515
Publication type: Paper in international publication
Authors: Esteban, Rafael, Buti, Maria, Rodriguez, Manuel, Lens, Sabela, Riveiro-Barciela, Mar, Garcia-Samaniego, Javier, Palom, Adriana, Rodriguez-Tajes, Sergio, Navascues, Carmen A et al.
DOI: 10.1111/apt.15521

Blog

News

The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.

On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.

Estudi sobre els patrons de consum habitual de l'alcohol en població jove

Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.

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