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Liver Diseases

The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.

Publications

Reconciling short-term clinical and Immunological outcomes of SARS-CoV-2 vaccination in Solid Organ Transplant recipients.

PMID: 34554648
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2022
Reference: Am J Transplant. 2022 Feb;22(2):673-675. doi: 10.1111/ajt.16855. Epub 2021 Oct 5.
Impact factor:
Publication type: Letter or abstract
Authors: Bestard, Oriol; Campins, Magda; Campos-Varela, Isabel; Castells, Lluis; Crespo, Elena; Esperalba, Juliana; Jouve, Thomas; Len, Oscar; Lopez, Manuel; Moreso, Francesc et al.
DOI: 10.1111/ajt.16855

What do we know about the impact of economic recessions on mortality inequalities? A critical review.

PMID: 35101740
Journal: SOCIAL SCIENCE & MEDICINE
Year: 2022
Reference: Soc Sci Med. 2022 Mar;296:114733. doi: 10.1016/j.socscimed.2022.114733. Epub 2022 Jan 22.
Impact factor:
Publication type: Review in international publication
Authors: Benach, Joan; Gutierrez, Manuela; Gutierrez-Zamora Navarro, Mariana; Martinez-Herrera, Eliana; Molina-Betancur, Juan Camilo; Padilla-Pozo, Alvaro; Pericas, Juan M; Zografos, Christos et al.
DOI: 10.1016/j.socscimed.2022.114733

Probability of HBsAg loss after nucleo(s)tide analogue withdrawal depends on HBV genotype and viral antigen levels.

PMID: 35092743
Journal: JOURNAL OF HEPATOLOGY
Year: 2022
Reference: J Hepatol. 2022 May;76(5):1042-1050. doi: 10.1016/j.jhep.2022.01.007. Epub 2022 Jan 29.
Impact factor:
Publication type: Paper in international publication
Authors: Agarwal, K; Ahn, S H; Berg, T; Boonstra, A; Brakenhoff, S M; Buti, M; Carey, I; Chen, C-H; Chiu, S-M; Cornberg, M et al.
DOI: 10.1016/j.jhep.2022.01.007

Dynamics of SARS-CoV-2 Alpha (B.1.1.7) variant spread: The wastewater surveillance approach.

PMID: 35074352
Journal: ENVIRONMENTAL RESEARCH
Year: 2022
Reference: Environ Res. 2022 May 15;208:112720. doi: 10.1016/j.envres.2022.112720. Epub 2022 Jan 22.
Impact factor:
Publication type: Paper in international publication
Authors: Andres, Cristina; Anton, Andres; Borrego, Carles M; Bosch, Albert; Carcereny, Albert; Chacon-Villanueva, Carme; Garcia-Cehic, Damir; Garcia-Pedemonte, David; Gregori, Josep; Guix, Susana et al.
DOI: 10.1016/j.envres.2022.112720

Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data.

PMID: 32980344
Journal: GASTROENTEROLOGY
Year: 2021
Reference: Gastroenterology. 2021 Jan;160(1):193-205.e10. doi: 10.1053/j.gastro.2020.09.026. Epub 2020 Sep 24.
Impact factor:
Publication type: Paper in international publication
Authors: Abraldes, Juan G; Albillos, Agustin; Alexandrino, Paula; Allegretti, Giulia; Alvarado, Edilmar; Amitrano, Lucio; Angrisani, Debora; Appenrodt, Beate; Augustin, Salvador; Bai, Wei et al.
DOI: 10.1053/j.gastro.2020.09.026

COVID-19 in Solid Organ Transplantation: A Matched Retrospective Cohort Study and Evaluation of Immunosuppression Management.

PMID: 32941394
Journal: TRANSPLANTATION
Year: 2021
Reference: Transplantation. 2021 Jan 1;105(1):138-150. doi: 10.1097/TP.0000000000003460.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Martinez, Carla; Anton, Andres; Berastegui, Cristina; Castells, Lluis; Del-Rio-Gutierrez, Jose-Manuel; Domenech, Laura; Garcia-Garcia, Sonia; Garcia-Ortega, Patricia; Gomez-Ganda, Laura; Gorgas-Torner, Maria-Queralt et al.
DOI: 10.1097/TP.0000000000003460

ENDPOINTS AND DESIGN OF CLINICAL TRIALS IN PATIENTS WITH DECOMPENSATED CIRRHOSIS: POSITION PAPER OF THE LIVERHOPE CONSORTIUM.

PMID: 32896580
Journal: JOURNAL OF HEPATOLOGY
Year: 2021
Reference: J Hepatol. 2021 Jan;74(1):200-219. doi: 10.1016/j.jhep.2020.08.009. Epub 2020 Sep 5.
Impact factor:
Publication type: Paper in international publication
Authors: Aban, M; Abraldes, J G; Alessandria, C; Avitabile, E; Bernardi, M; Beuers, U; Campion, D; Caraceni, P; Carol, M; Cervera, M et al.
DOI: 10.1016/j.jhep.2020.08.009

Epidemiological pattern, incidence and outcomes of COVID-19 in liver transplant patients.

PMID: 32750442
Journal: JOURNAL OF HEPATOLOGY
Year: 2021
Reference: J Hepatol. 2021 Jan;74(1):148-155. doi: 10.1016/j.jhep.2020.07.040. Epub 2020 Aug 1.
Impact factor:
Publication type: Paper in international publication
Authors: Alamo, Jose Maria; Arias-Milla, Ana; Blanco-Fernandez, Gerardo; Bustamante-Schneider, Javier; Caballero, Aranzazu; Cachero, Alba; Castells, Lluis; Colmenero, Jordi; De la Rosa, Gloria; Fabrega, Emilio et al.
DOI: 10.1016/j.jhep.2020.07.040

Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients.

PMID: 32752979
Journal: Emerging Microbes & Infections
Year: 2020
Reference: Emerg Microbes Infect. 2020 Dec;9(1):1900-1911. doi: 10.1080/22221751.2020.1806735.
Impact factor: 5.776
Publication type: Paper in international publication
Authors: Almirante, Benito, Esteban, Juan Ignacio, Pumarola, Tomas, Anton, Andres, Quer, Josep, Ferrer, Ricard, Campins, Magda, Martin, Maria Carmen, Quer, Susanna, Andres, Cristina et al.
DOI: 10.1080/22221751.2020.1806735

GEHEP 010 STUDY: PREVALENCE AND DISTRIBUTION OF HEPATITIS B VIRUS GENOTYPES IN SPAIN (2000-2016).

PMID: 32711039
Journal: JOURNAL OF INFECTION
Year: 2020
Reference: J Infect. 2020 Oct;81(4):600-606. doi: 10.1016/j.jinf.2020.07.019. Epub 2020 Jul 22.
Impact factor: 4.842
Publication type: Paper in international publication
Authors: Fernandez-Cuenca, Felipe, Garcia-Arata, Isabel, Reina, Gabriel, Ocete, Maria Dolores, Fuentes, Ana, de la Cruz, Daniel Navarro, Nieto, Leonardo, de Castro, Ana Blazquez, Buti, Maria, Alvarez, Marta et al.
DOI: 10.1016/j.jinf.2020.07.019

Application of EASL 2017 criteria for switching hepatitis B patients from tenofovir disoproxil to entecavir or tenofovir alafenamide.

PMID: 32703729
Journal: DIGESTIVE AND LIVER DISEASE
Year: 2020
Reference: Dig Liver Dis. 2020 Oct;52(10):1164-1169. doi: 10.1016/j.dld.2020.06.037. Epub 2020 Jul 20.
Impact factor: 3.57
Publication type: Paper in international publication
Authors: Roade, Luisa, Loglio, Alessandro, Borghi, Marta, Riveiro-Barciela, Mar, Soffredini, Roberta, Facchetti, Floriana, di Paolo, Dhanai, Tabernero, David, Lunghi, Giovanna, Esteban, Rafael et al.
DOI: 10.1016/j.dld.2020.06.037

Metabolic comorbidity, the new enemy. Metabolic syndrome and steatohepatitis.

PMID: 32697274
Journal: Revista espanola de sanidad penitenciaria
Year: 2020
Reference: Rev Esp Sanid Penit. 2020 May-Aug;22(2):55-57. doi: 10.18176/resp.00010.
Impact factor: 0
Publication type: Editorail in international publication
Authors: Rivera Esteban, J M, Augustin Recio, S et al.
DOI: 10.18176/resp.00010

Blog

News

The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.

On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.

Estudi sobre els patrons de consum habitual de l'alcohol en població jove

Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.

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