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Microbiology

The Microbiology research group of the Vall d'Hebron Research Institute (VHIR) focuses on the study of microbiological aspects —in basic, translational and clinical research— that could improve the outcome of patients with infectious diseases.

Our priority research areas are:

  • Microbiological surveillance of emerging and re-emerging infectious diseases.
    • Diseases due to viral infections of the respiratory tract
    • Microorganisms that cause vaccine-preventable diseases
    • Infectious diseases of sexual transmission
  • Antimicrobial resistance
  • Sepsis
  • Development and validation of rapid microbiological diagnostic devices.
  • International Health
  • Hepatitis 

We actively collaborate with other microbiology laboratories, health services, national and international centres and organizations, as well as with the different research networks of the Carlos III Health Institute in Spain.

In addition, we carry out an important activity in the surveillance of the genotypic and phenotypic evolution of microorganisms present in the community in terms of their virulence, transmissibility, antigenic escape and antimicrobial resistance, in collaboration with public administrations, both at the national and international level.
 

Publications

Mycotic aneurysm of Internal Carotid Artery Secondary to Livestock-associated Methicillin-resistant Staphylococcus Aureus Clonal Complex CC398.

PMID: 34481883
Journal: ANNALS OF VASCULAR SURGERY
Year: 2022
Reference: Ann Vasc Surg. 2022 Jan;78:379.e7-379.e10. doi: 10.1016/j.avsg.2021.06.031. Epub 2021 Sep 3.
Impact factor: 1.466
Publication type: Letter or abstract
Authors: Bellmunt-Montoya, Sergi; Gonzalez-Lopez, Juan Jose; Escola-Verge, Laura; Tenezaca-Sari, Xavier; Gil-Sala, Daniel; Lung, Mayli et al.
DOI: 10.1016/j.avsg.2021.06.031

A year living with SARS-CoV-2: an epidemiological overview of viral lineage circulation by whole-genome sequencing in Barcelona city (Catalonia, Spain).

PMID: 34842496
Journal: Emerging Microbes & Infections
Year: 2022
Reference: Emerg Microbes Infect. 2022 Dec;11(1):172-181. doi: 10.1080/22221751.2021.2011617.
Impact factor: 7.163
Publication type: Paper in international publication
Authors: Andres, Cristina; Pinana, Maria; Borras-Bermejo, Blanca; Gonzalez-Sanchez, Alejandra; Garcia-Cehic, Damir; Esperalba, Juliana; Rando, Ariadna; Zules-Ona, Ricardo-Gabriel; Campos, Carolina; Codina, Maria Gema et al.
DOI: 10.1080/22221751.2021.2011617

Humoral and Cellular Responses to SARS-CoV-2 in Convalescent COVID-19 Patients With Multiple Sclerosis.

PMID: 35105687
Journal: Neurology-Neuroimmunology & Neuroinflammation
Year: 2022
Reference: Neurol Neuroimmunol Neuroinflamm. 2022 Feb 1;9(2). pii: 9/2/e1143. doi: 10.1212/NXI.0000000000001143. Print 2022 Mar.
Impact factor: 8.485
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Zabalza, Ana; Nos, Carlos; Sastre-Garriga, Jaume; Tintore, Mar; Montalban, Xavier; Comabella, Manuel; Espejo, Carmen; Castillo, Joaquin; Otero-Romero, Susana et al.
DOI: 10.1212/NXI.0000000000001143

Reconciling short-term clinical and Immunological outcomes of SARS-CoV-2 vaccination in Solid Organ Transplant recipients.

PMID: 34554648
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2022
Reference: Am J Transplant. 2022 Feb;22(2):673-675. doi: 10.1111/ajt.16855. Epub 2021 Oct 5.
Impact factor: 8.086
Publication type: Letter or abstract
Authors: Toapanta, Nestor; Esperalba, Juliana; Campos-Varela, Isabel; Pont, Teresa; Len, Oscar; Campins, Magda; Moreso, Francesc; Crespo, Elena; Munoz, Marina; Lopez, Manuel et al.
DOI: 10.1111/ajt.16855

Necrotizing pneumonia due to Streptococcus pneumoniae in children during the period of non-systematic use of PCV13 in Catalonia, Spain.

PMID: 34865709
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2021
Reference: Enferm Infecc Microbiol Clin. 2021 Dec;39(10):486-492. doi: 10.1016/j.eimce.2020.08.009.
Impact factor: 1.731
Publication type: Paper in international publication
Authors: Salleras, Luis, Gonzalez-Peris, Sebastia, Campins, Magda, Garcia-Garcia, Juan Jose, Diaz-Conradi, Alvaro, Dominguez, Angela, Ciruela, Pilar, de Sevilla, Mariona F, Hernandez, Sergi, Munoz-Almagro, Carmen et al.
DOI: 10.1016/j.eimce.2020.08.009

Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018.

PMID: 34853333
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Dec 1;11(1):23218. doi: 10.1038/s41598-021-02348-2.
Impact factor: 4.38
Publication type: Paper in international publication
Authors: Parron, Ignacio, de Simon, Merce, Rius, Cristina, Dominguez, Angela, Soldevila, Nuria, Bartolome, Rosa, Cornejo-Sanchez, Thais, Jane, Mireia, Martinez, Ana, Torner, Nuria et al.
DOI: 10.1038/s41598-021-02348-2

COVID-19 Clinical Profile in Latin American Migrants Living in Spain: Does the Geographical Origin Matter?

PMID: 34830495
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Nov 9;10(22). pii: jcm10225213. doi: 10.3390/jcm10225213.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Sempere, Abiu, Salvador, Fernando, Monforte, Arnau, Sampol, Julia, Espinosa-Pereiro, Juan, Miarons, Marta, Bosch-Nicolau, Pau, Guillen-Del-Castillo, Alfredo, Aznar, Maria Luisa, Campos-Varela, Isabel et al.
DOI: 10.3390/jcm10225213

Expression of Chimeric HPV-HIV Protein L1P18 in Pichia pastoris; Purification and Characterization of the Virus-like Particles.

PMID: 34834382
Journal: Pharmaceutics
Year: 2021
Reference: Pharmaceutics. 2021 Nov 20;13(11). pii: pharmaceutics13111967. doi: 10.3390/pharmaceutics13111967.
Impact factor: 6.321
Publication type: Paper in international publication
Authors: Saubi, Narcis, Ferrer, Pau, Joseph-Munne, Joan, Eto, Yoshiki et al.
DOI: 10.3390/pharmaceutics13111967

Necrotizing pneumonia due to Streptococcus pneumoniae in children during the period of non-systematic use of PCV13 in Catalonia, Spain.

PMID: 33131931
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2020
Reference: Enferm Infecc Microbiol Clin. 2020 Oct 29. pii: S0213-005X(20)30291-3. doi: 10.1016/j.eimc.2020.08.022.
Impact factor: 1.654
Publication type: Paper in national publication
Authors: Gonzalez-Peris, Sebastia, Campins, Magda, Garcia-Garcia, Juan Jose, Diaz-Conradi, Alvaro, Dominguez, Angela, Ciruela, Pilar, de Sevilla, Mariona F, Hernandez, Sergi, Izquierdo, Conchita, Codina, Gemma et al.
DOI: 10.1016/j.eimc.2020.08.022

Design Concepts of Virus-Like Particle-Based HIV-1 Vaccines.

PMID: 33117367
Journal: Frontiers in Immunology
Year: 2020
Reference: Front Immunol. 2020 Sep 30;11:573157. doi: 10.3389/fimmu.2020.573157. eCollection 2020.
Impact factor: 5.085
Publication type: Review in international publication
Authors: Chen, Chun-Wei, Saubi, Narcis, Joseph-Munne, Joan et al.
DOI: 10.3389/fimmu.2020.573157

Antimicrobial susceptibility of Neisseria gonorrhoeae in Barcelona during a five-year period, 2013 to 2017.

PMID: 33094716
Journal: Eurosurveillance
Year: 2020
Reference: Euro Surveill. 2020 Oct;25(42). doi: 10.2807/1560-7917.ES.2020.25.42.1900576.
Impact factor: 6.454
Publication type: Paper in international publication
Authors: Alberny, Mireia, Jane, Mireia, Larrosa, Nieves, Pumarola, Tomas, Hoyos-Mallecot, Yannick, Serra-Pladevall, Judit, Barbera, Maria Jesus, Hernandez, Marta, El Ouazzani, Rachid, Vinado, Belen et al.
DOI: 10.2807/1560-7917.ES.2020.25.42.1900576

Isolated cerebral mucormycosis associated with intravenous drug use.

PMID: 33067115
Journal: JOURNAL DE MYCOLOGIE MEDICALE
Year: 2020
Reference: J Mycol Med. 2020 Dec;30(4):101046. doi: 10.1016/j.mycmed.2020.101046. Epub 2020 Oct 6.
Impact factor: 1.56
Publication type: Letter or abstract
Authors: Dura-Miralles, X, Escola-Verge, L, Moreno, D, Martinez-Ricarte, F, Lung, M, Fernandez-Hidalgo, N, Auger, C, Martin-Gomez, M-T et al.
DOI: 10.1016/j.mycmed.2020.101046

Early oral switch to linezolid for low-risk patients with Staphylococcus aureus bloodstream infections: a propensity-matched cohort study.

PMID: 30351401
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2019
Reference: Clin Infect Dis. 2019 Jul 18;69(3):381-387. doi: 10.1093/cid/ciy916.
Impact factor: 9.055
Publication type: Paper in international publication
Authors: Willekens, Rein, Puig-Asensio, Mireia, Ruiz-Camps, Isabel, Larrosa, Maria N, Gonzalez-Lopez, Juan J, Rodriguez-Pardo, Dolors, Fernandez-Hidalgo, Nuria, Pigrau, Carles, Almirante, Benito et al.
DOI: 10.1093/cid/ciy916

Designing Chimeric Virus-like Particle-based Vaccines for Human Papillomavirus and HIV: Lessons Learned.

PMID: 31834327
Journal: AIDS REVIEWS
Year: 2019
Reference: AIDS Rev. 2019;21(4):218-232. doi: 10.24875/AIDSRev.19000114.
Impact factor: 2.357
Publication type: Paper in international publication
Authors: Eto, Yoshiki, Saubi, Narcis, Ferrer, Pau, Joseph, Joan et al.
DOI: 10.24875/AIDSRev.19000114

(1)H-NMR Urinary Metabolic Profile, A Promising Tool for the Management of Infants with Human Cytomegalovirus-Infection.

PMID: 31775291
Journal: Metabolites
Year: 2019
Reference: Metabolites. 2019 Nov 25;9(12). pii: metabo9120288. doi: 10.3390/metabo9120288.
Impact factor: 3.303
Publication type: Paper in international publication
Authors: Frick, Marie Antoinette, Barba, Ignasi, Fenoy-Alejandre, Marina, Lopez-Lopez, Paula, Baquero-Artigao, Fernando, Rodriguez-Molino, Paula, Nicolas-Lopez, Marta, de la Fuente-Juarez, Asuncion, Codina-Grau, Maria Gemma, Esperalba Esquerra, Juliana et al.
DOI: 10.3390/metabo9120288

Population dynamics and antigenic drift of Bordetella pertussis following whole cell vaccine replacement, Barcelona, Spain, 1986-2015.

PMID: 31769735
Journal: Emerging Microbes & Infections
Year: 2019
Reference: Emerg Microbes Infect. 2019;8(1):1711-1720. doi: 10.1080/22221751.2019.1694395.
Impact factor: 6.212
Publication type: Paper in international publication
Authors: Jane, Mireia, Pumarola, Tomas, Fabrega, Anna, Gonzalez-Lopez, Juan Jose, Campins, Magda, Rodrigo, Carlos, Rajadell, Mireia, Mir-Cros, Alba, Moreno-Mingorance, Albert, Martin-Gomez, M Teresa et al.
DOI: 10.1080/22221751.2019.1694395

Blog

News

The collaboration will focus on several key areas of mutual interest in microbiology in particular antimicrobial resistance and stewardship.

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

The new diagnostic method, designed for use in endemic regions, combines a mobile application with a low-cost robotic microscope.