About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
PMID: 34969818 Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Year: 2022 Reference: J Am Soc Nephrol. 2022 Jan;33(1):6-8. doi: 10.1681/ASN.2021111471. Impact factor: 10.121 Publication type: Editorail in international publication Authors: Bestard, Oriol; Crespo, Elena et al. DOI: 10.1681/ASN.2021111471
PMID: 34554648 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2022 Reference: Am J Transplant. 2022 Feb;22(2):673-675. doi: 10.1111/ajt.16855. Epub 2021 Oct 5. Impact factor: 8.086 Publication type: Letter or abstract Authors: Toapanta, Nestor; Esperalba, Juliana; Campos-Varela, Isabel; Pont, Teresa; Len, Oscar; Campins, Magda; Moreso, Francesc; Crespo, Elena; Munoz, Marina; Lopez, Manuel et al. DOI: 10.1111/ajt.16855
PMID: 35124011 Journal: KIDNEY INTERNATIONAL Year: 2022 Reference: Kidney Int. 2022 May;101(5):1027-1038. doi: 10.1016/j.kint.2021.12.029. Epub 2022 Feb 4. Impact factor: 10.612 Publication type: Paper in international publication Authors: Fava, Alexandre; Donadeu, Laura; Jouve, Thomas; Gonzalez-Costello, Jose; Llado, Laura; Santana, Carolina; Toapanta, Nestor; Lopez, Manuel; Pernin, Vincent; Facundo, Carme et al. DOI: 10.1016/j.kint.2021.12.029
PMID: 35137195 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Feb 7. pii: 6523371. doi: 10.1093/ndt/gfac029. Impact factor: 5.992 Publication type: Paper in international publication Authors: Decramer, Stephane; Devuyst, Olivier; van Dyck, Maria; Ferraro, Pietro Manuel; Fila, Marc; Francisco, Telma; Ghiggeri, Gian Marco; Gondra, Leire; Guarino, Stefano; Hooman, Nakysa et al. DOI: 10.1093/ndt/gfac029
PMID: 34768461 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Oct 26;10(21). pii: jcm10214941. doi: 10.3390/jcm10214941. Impact factor: 4.242 Publication type: Paper in international publication Authors: Sans-Pola, Carla, Agusti, Antonia, Bosch, Josep Angel, Agraz, Irene, Alerany, Carmen, Danes, Immaculada et al. DOI: 10.3390/jcm10214941
PMID: 34739540 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2021 Reference: Nephrol Dial Transplant. 2021 Dec 28;37(Supplement_2):ii55-ii62. doi: 10.1093/ndt/gfab261. Impact factor: 5.992 Publication type: Paper in international publication Authors: Unwin, Robert, Garneata, Liliana, Gesualdo, Loreto, Giannakou, Konstantinos, Goumenos, Dimitrios, Kartal, Ayse Tugba, Mani, Laila-Yasmin, Marti, Hans-Peter, Mayer, Christopher, Nielsen, Rikke et al. DOI: 10.1093/ndt/gfab261
PMID: 34622093 Journal: Kidney International Reports Year: 2021 Reference: Kidney Int Rep. 2021 Aug 18;6(10):2535-2536. doi: 10.1016/j.ekir.2021.08.007. eCollection 2021 Oct. Impact factor: 4.164 Publication type: Editorail in international publication Authors: Bolufer Cardona, Monica, Soler Romeo, Maria Jose, McMahon, Gearoid M et al. DOI: 10.1016/j.ekir.2021.08.007
PMID: 34603691 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2021 Apr 7;14(10):2142-2150. doi: 10.1093/ckj/sfab075. eCollection 2021 Oct. Impact factor: 4.452 Publication type: Paper in international publication Authors: Stevens, Kate I, Melilli, Edoardo, Diniz, Hugo, Gillis, Keith, Guerrot, Dominique, Montero, Nuria, Soler, Maria Jose, Desai, Tejas et al. DOI: 10.1093/ckj/sfab075
PMID: 32085620 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2020 Reference: Int J Mol Sci. 2020 Feb 18;21(4). pii: ijms21041372. doi: 10.3390/ijms21041372. Impact factor: 4.556 Publication type: Paper in international publication Authors: Garcia-Vives, Eloi, Sole, Cristina, Moline, Teresa, Vidal, Marta, Agraz, Irene, Ordi-Ros, Josep, Cortes-Hernandez, Josefina et al. DOI: 10.3390/ijms21041372
PMID: 32076718 Journal: CLINICAL INFECTIOUS DISEASES Year: 2020 Reference: Clin Infect Dis. 2020 Dec 3;71(9):2375-2385. doi: 10.1093/cid/ciz1209. Impact factor: 8.313 Publication type: Paper in international publication Authors: Cruzado, Josep M, Jarque, Marta, Crespo, Elena, Melilli, Edoardo, Gutierrez, Alex, Moreso, Francesc, Guirado, Lluis, Revuelta, Ignacio, Montero, Nuria, Torras, Joan et al. DOI: 10.1093/cid/ciz1209
PMID: 32046355 Journal: Journal of Clinical Medicine Year: 2020 Reference: J Clin Med. 2020 Feb 8;9(2). pii: jcm9020472. doi: 10.3390/jcm9020472. Impact factor: 3.303 Publication type: Review in international publication Authors: Garcia-Fernandez, Nuria, Jacobs-Cacha, Conxita, Mora-Gutierrez, Jose Maria, Vergara, Ander, Orbe, Josune, Soler, Maria Jose et al. DOI: 10.3390/jcm9020472
PMID: 31869590 Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES Year: 2020 Reference: J Neurol Sci. 2020 Feb 15;409:116635. doi: 10.1016/j.jns.2019.116635. Epub 2019 Dec 14. Impact factor: 3.115 Publication type: Paper in international publication Authors: Jimenez-Balado, Joan, Riba-Llena, Iolanda, Pizarro, Jesus, Palasi, Antoni, Penalba, Anna, Ramirez, Clara, Maisterra, Olga, Espinel, Eugenia, Ramos, Natalia, Pujadas, Francesc et al. DOI: 10.1016/j.jns.2019.116635
The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.
Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.
The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.
