About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The research conducted in our group is geared toward elucidating the cause and molecular mechanisms of neurodegeneration in Parkinson's disease (PD), a disabling, currently incurable common neurodegenerative disorder. To this end, we perform clinical and pre-clinical translational research in both PD patients and in human-relevant experimental in vitro and in vivo PD-related models.
Elucidating the molecular mechanisms underlying neurodegeneration in PD should allow to:
Mitochondria are highly dynamic organelles with complex structural features that play several important cellular functions, such as the production of energy by oxidative phosphorylation, the regulation of calcium homeostasis, or the control of programmed cell death. Given its essential role in neuronal viability, alterations in mitochondrial biology can lead to neuron dysfunction and cell death. Defects in mitochondrial respiration have long been implicated in the etiology and pathogenesis of Parkinson's disease (PD). However, the role of mitochondria in PD extends well beyond defective respiration and also involves perturbations in mitochondrial dynamics, leading to alterations in mitochondrial morphology, intracellular trafficking, or quality control. Whether a primary or secondary event, mitochondrial dysfunction holds promise as a potential therapeutic target to halt the progression of dopaminergic neurodegeneration in PD.
IP: Miquel Vila Bover
IP: Miquel Vila Bover Collaborators: - Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 0.01 Reference: RED2022-134786-T Duration: 01/06/2023 - 31/05/2025
IP: Marta Martínez Vicente Collaborators: Pablo Castillo Sánchez, Laia Perez Lasarte Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 73383.97 Reference: AGAUR/FI/2023/CASTILLO Duration: 01/06/2023 - 31/05/2026
IP: Ariadna Laguna Tuset Collaborators: - Funding agency: Parkinson's Foundation Funding: 54466.62 Reference: PARKINSON.F_IMPACT2022 Duration: 01/07/2022 - 31/07/2025
IP: Anna Rosell Novel Collaborators: Mercedes Arrúe Gonzalo, Joan Montaner Villalonga, Anna Penalba Morenilla, Maria Mar Hernandez Guillamon, Olga Maisterra Santos, Maria Pilar Delgado Martínez, Antonio Palasi Franco, Jesús Pizarro Gonzálvez, Miguel García Gabilondo, Nicolas Garcia Rodriguez Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 40000 Reference: 2021 SGR 00656 Duration: 01/01/2022 - 30/06/2025
PMID: 38605602 Journal: ESC Heart Failure Year: 2024 Reference: ESC Heart Fail. 2024 Apr 11. doi: 10.1002/ehf2.14756. Impact factor: Publication type: Paper in international publication Authors: Adao, Luis; Basilio, Carla; Chico-Carballas, Juan Ignacio; Costa, Catarina; Duraes-Campos, Isabel; Ferreira, Ana Rita; Gaiao, Sergio; Lebreiro, Ana Margarida; Neves, Aida; Paiva, Jose Artur et al. DOI: 10.1002/ehf2.14756
PMID: 38651584 Journal: PERFUSION-UK Year: 2024 Reference: Perfusion. 2024 Apr;39(1_suppl):23S-38S. doi: 10.1177/02676591241236650. Impact factor: Publication type: Paper in international publication Authors: Belliato, Mirko; Belohlavek, Jan; Brodie, Daniel; Broman, Lars Mikael; Chen, Yih-Sharng; Cho, Sung-Min; Di Mauro, Michele; Fraser, John F; Jung, Jae-Seung; Lorusso, Roberto et al. DOI: 10.1177/02676591241236650
PMID: 38753268 Journal: INTENSIVE CARE MEDICINE Year: 2024 Reference: Intensive Care Med. 2024 May 16. doi: 10.1007/s00134-024-07479-4. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Alcantara Carmona, Sara; Blandino, Aaron; Contreras, Sofia; Del Saz, Ana; Riera, Jordi et al. DOI: 10.1007/s00134-024-07479-4
PMID: 39047057 Journal: ANALYTICAL CHEMISTRY Year: 2024 Reference: Anal Chem. 2024 Jul 24. doi: 10.1021/acs.analchem.4c02654. Impact factor: Publication type: Paper in international publication Authors: Arranz-Amo, Jose Antonio; Camprodon-Gomez, Maria; Carnicer-Caceres, Clara; Castillo-Ribelles, Laura; Enriquez-Calzada, Silvia; Ferrer, Roser; Gonzalo, Mercedes Arrue; Hernandez-Vara, Jorge; Laguna, Ariadna; Martinez-Vicente, Marta et al. DOI: 10.1021/acs.analchem.4c02654
PMID: 36766830 Journal: Cells Year: 2023 Reference: Cells. 2023 Feb 2;12(3):487. doi: 10.3390/cells12030487. Impact factor: Publication type: Paper in international publication Authors: Comella, Joan X; de la Rosa, Enrique J; de la Villa, Pedro; Hernandez-Sanchez, Catalina; Lopez-Soriano, Joaquin; Mendez, Ana; Pazo-Gonzalez, Mateo; Sires, Anna; Sole, Montse et al. DOI: 10.3390/cells12030487
PMID: 36835866 Journal: Journal of Clinical Medicine Year: 2023 Reference: J Clin Med. 2023 Feb 7;12(4):1329. doi: 10.3390/jcm12041329. Impact factor: Publication type: Paper in international publication Authors: Alonso Losada, Maria G; Alonso Redondo, Ruben; Alvarez Sauco, Maria; Ardura, Jessica Gonzalez; Avila Rivera, Maria A; Borrue, Carmen; Boungiorno, Maria Teresa; Caballol, Nuria; Cabo, Iria; Carrillo Padilla, Francisco et al. DOI: 10.3390/jcm12041329
PMID: 36853601 Journal: PERFUSION-UK Year: 2023 Reference: Perfusion. 2023 May;38(1_suppl):40-43. doi: 10.1177/02676591231160462. Epub 2023 Feb 28. Impact factor: Publication type: Paper in international publication Authors: Domenech, Josep; Domenech, Laura; Ferrer, Ricard; Gallart, Elisabet; Garcia, Sonia; Garcia, Sonia; Giron, Pilar; Lamora, Anna; Lamora, Anna; Nuvials, Xavier et al. DOI: 10.1177/02676591231160462
PMID: 37890368 Journal: EBioMedicine Year: 2023 Reference: EBioMedicine. 2023 Oct 25;97:104841. doi: 10.1016/j.ebiom.2023.104841. Impact factor: Publication type: Paper in international publication Authors: Alonso Luengo, Olga; Alonso-Lopez, Elisa; Arto Millan, Luis Maria; Avendano-Ortiz, Jose; Belanger Quintana, Amaya; Camprodon Gomez, Maria; Correcher Medina, Patricia; Cubillos-Zapata, Carolina; Cueto, Francisco J; Del Castillo, Francisco J et al. DOI: 10.1016/j.ebiom.2023.104841
PMID: 35651347 Journal: Frontiers in Neurology Year: 2022 Reference: Front Neurol. 2022 May 16;13:835249. doi: 10.3389/fneur.2022.835249. eCollection 2022. Impact factor: Publication type: Paper in international publication Authors: Bayes, Angels; Buongiorno, Mariateresa; Caballol, Nuria; Escalante-Arroyo, Sonia; Gironell, Alexandre; Hernandez-Vara, Jorge; Lopez-Ariztegui, Nuria; Lopez-Manzanares, Lydia; Lopez-Sanchez, Jose; Martinez-Castrillo, Juan Carlos et al. DOI: 10.3389/fneur.2022.835249
PMID: 35626303 Journal: Diagnostics Year: 2022 Reference: Diagnostics (Basel). 2022 May 5;12(5). pii: diagnostics12051147. doi: 10.3390/diagnostics12051147. Impact factor: Publication type: Paper in international publication Authors: Aguilar, Miquel; Alonso, Pilar Sanchez; Aramburu, Isabel Gonzalez; Ardura, Jessica Gonzalez; Ariztegui, Nuria Lopez; Bartolome, Carlos Cores; Borrue, Carmen; Caballol, Nuria; Cabo, Iria; Caldentey, Juan Garcia et al. DOI: 10.3390/diagnostics12051147
PMID: 35633051 Journal: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY Year: 2022 Reference: Int J Geriatr Psychiatry. 2022 May 17;37(6). doi: 10.1002/gps.5761. Impact factor: Publication type: Paper in international publication Authors: Aguilar, Miquel; Alonso Losada, Maria G; Alonso Redondo, Ruben; Alvarez Sauco, Maria; Ariztegui, Nuria Lopez; Avila Rivera, Maria A; Blazquez Estrada, Marta; Borrue, Carmen; Caballol, Nuria; Cabo, Iria et al. DOI: 10.1002/gps.5761
PMID: 35429504 Journal: NEUROPHARMACOLOGY Year: 2022 Reference: Neuropharmacology. 2022 Jul 1;212:109058. doi: 10.1016/j.neuropharm.2022.109058. Epub 2022 Apr 13. Impact factor: Publication type: Paper in international publication Authors: Abass, Doaa; Abian, Joaquin; Carrascal, Montserrat; Gil, Carles; Giraldo, Jesus; Gonzalez-Sepulveda, Marta; Hamdon, Sally; Ma, Guofen; Martinez-Rivas, Anna; Moreno-Delgado, David et al. DOI: 10.1016/j.neuropharm.2022.109058
PMID: 34679503 Journal: Diagnostics Year: 2021 Reference: Diagnostics (Basel). 2021 Sep 29;11(10). pii: diagnostics11101801. doi: 10.3390/diagnostics11101801. Impact factor: Publication type: Paper in international publication Authors: Aguilar, Miquel; Alonso Losada, Maria G; Alonso Redondo, Ruben; Alvarez Sauco, Maria; Avila Rivera, Maria A; Blazquez Estrada, Marta; Borrue, Carmen; Caballol, Nuria; Cabo, Iria; Canfield, Hector et al. DOI: 10.3390/diagnostics11101801
PMID: 34563704 Journal: AGEING RESEARCH REVIEWS Year: 2021 Reference: Ageing Res Rev. 2021 Dec;72:101468. doi: 10.1016/j.arr.2021.101468. Epub 2021 Sep 24. Impact factor: Publication type: Review in international publication Authors: Arias, Esperanza; Cuervo, Ana Maria; Kaushik, Susmita; Martinez-Vicente, Marta; Pampliega, Olatz; Tasset, Inmaculada; Wong, Esther et al. DOI: 10.1016/j.arr.2021.101468
PMID: 34514046 Journal: Movement Disorders Clinical Practice Year: 2021 Reference: Mov Disord Clin Pract. 2021 Sep 3;8(Suppl 1):S37-S39. doi: 10.1002/mdc3.13295. eCollection 2021 Aug. Impact factor: Publication type: Letter or abstract Authors: Camprodon-Gomez, Maria; Hernandez-Vara, Jorge; Lucas-Del-Pozo, Sara; Moreno-Martinez, Daniel; Moreno-Martinez, David et al. DOI: 10.1002/mdc3.13295
PMID: 34514047 Journal: Movement Disorders Clinical Practice Year: 2021 Reference: Mov Disord Clin Pract. 2021 Sep 3;8(Suppl 1):S40-S41. doi: 10.1002/mdc3.13304. eCollection 2021 Aug. Impact factor: Publication type: Editorail in international publication Authors: Camprodon-Gomez, Maria; Friedman, Jennifer; Hernandez-Vara, Jorge; Kurian, Manju A; Lucas-Del-Pozo, Sara; Moreno-Martinez, Daniel; Moreno-Martinez, David et al. DOI: 10.1002/mdc3.13304
PMID: 32767480 Journal: Annals of Clinical and Translational Neurology Year: 2020 Reference: Ann Clin Transl Neurol. 2020 Aug;7(8):1436-1442. doi: 10.1002/acn3.51095. Epub 2020 Aug 6. Impact factor: Publication type: Paper in international publication Authors: Correa-Vela, Marta; Darling, Alejandra; Espinos, Carmen; Fernandez-Rodriguez, Sandra; Hernandez-Vara, Jorge; Jenkins, Alison; Lupo, Vincenzo; Macaya, Alfons; Marce-Grau, Anna; Martinez-Vicente, Marta et al. DOI: 10.1002/acn3.51095
PMID: 32708733 Journal: Cancers Year: 2020 Reference: Cancers (Basel). 2020 Jul 16;12(7). pii: cancers12071922. doi: 10.3390/cancers12071922. Impact factor: Publication type: Paper in international publication Authors: Antonelli, Roberta; Bove, Jordi; Gallego, Soledad; Hooker, Jacob M; Jimenez, Carlos; Martinez-Saez, Elena; Martini, Maurizio; Moreno, Lucas; Riccardi, Riccardo; Riley, Misha et al. DOI: 10.3390/cancers12071922
PMID: 32682292 Journal: PARKINSONISM & RELATED DISORDERS Year: 2020 Reference: Parkinsonism Relat Disord. 2020 Sep;78:31-35. doi: 10.1016/j.parkreldis.2020.06.037. Epub 2020 Jul 4. Impact factor: Publication type: Paper in international publication Authors: Armengol-Bellapart, M; Carter, S; Castell-Conesa, J; Corominas-Roso, M; Cuberas-Borros, G; Hernandez-Vara, J; Lorenzo-Bosquet, C; Lucas-Del Pozo, S; Saez-Francas, N et al. DOI: 10.1016/j.parkreldis.2020.06.037
PMID: 32607644 Journal: JOURNAL OF NEUROLOGY Year: 2020 Reference: J Neurol. 2020 Nov;267(11):3400-3410. doi: 10.1007/s00415-020-10018-y. Epub 2020 Jun 30. Impact factor: Publication type: Paper in international publication Authors: Aracil-Bolanos, Ignacio; Bejr-Kasem, Helena; Calopa, Matilde; Campolongo, Antonia; Crespo-Cuevas, Ane; de Fabregues, Oriol; Horta-Barba, Andrea; Izquierdo-Barrionuevo, Cristina; Kulisevsky, Jaime; Marin-Lahoz, Juan et al. DOI: 10.1007/s00415-020-10018-y
PMID: 30846695 Journal: Nature Communications Year: 2019 Reference: Nat Commun. 2019 Mar 7;10(1):973. doi: 10.1038/s41467-019-08858-y. Impact factor: Publication type: Paper in international publication Authors: Ballabio, Andrea; Bortolozzi, Analia; Bove, Jordi; Carballo-Carbajal, Iria; Cuadros, Thais; Gelpi, Ellen; Gonzalez-Sepulveda, Marta; Hasegawa, Takafumi; Laguna, Ariadna; Martinez-Vicente, Marta et al. DOI: 10.1038/s41467-019-08858-y
PMID: 30415891 Journal: EBioMedicine Year: 2019 Reference: EBioMedicine. 2019 Jan;39:497-509. doi: 10.1016/j.ebiom.2018.10.071. Epub 2018 Nov 8. Impact factor: Publication type: Paper in international publication Authors: Artacho, Alejandro; Compte, Joan; Francino, M Pilar; Gosalbes, Maria Jose; Jimenez-Hernandez, Nuria; Moriano-Gutierrez, Silvia; Pons, Xavier; Valles, Yvonne et al. DOI: 10.1016/j.ebiom.2018.10.071
PMID: 30675930 Journal: MOVEMENT DISORDERS Year: 2019 Reference: Mov Disord. 2019 Feb;34(2):161-163. doi: 10.1002/mds.27618. Epub 2019 Jan 24. Impact factor: Publication type: Editorail in international publication Authors: Blesa, Javier; Vila, Miquel et al. DOI: 10.1002/mds.27618
PMID: 31731485 Journal: Cells Year: 2019 Reference: Cells. 2019 Oct 25;8(11). pii: cells8111317. doi: 10.3390/cells8111317. Impact factor: 5.656 Publication type: Review in international publication Authors: Xicoy, Helena, Penuelas, Nuria, Vila, Miquel, Laguna, Ariadna et al. DOI: 10.3390/cells8111317
PMID: 29695377 Journal: JMIR rehabilitation and assistive technologies Year: 2018 Reference: JMIR Rehabil Assist Technol. 2018 Apr 25;5(1):e8. doi: 10.2196/rehab.8335. Impact factor: Publication type: Paper in international publication Authors: Alvarez, Ramiro; Bayes, Angels; Catala, Andreu; de Mingo, Eva; Hernandez-Vara, Jorge; Moral, Alfons; Perez-Lopez, Carlos; Perez-Martinez, David A; Rodriguez-Martin, Daniel; Rodriguez-Molinero, Alejandro et al. DOI: 10.2196/rehab.8335
PMID: 29628303 Journal: MOLECULAR THERAPY Year: 2018 Reference: Mol Ther. 2018 Jun 6;26(6):1552-1567. doi: 10.1016/j.ymthe.2018.02.022. Epub 2018 Feb 27. Impact factor: Publication type: Paper in international publication Authors: Ballabio, Andrea; Bortolozzi, Analia; Bove, Jordi; Cuadros, Thais; Parent, Annabelle; Rodriguez-Galvan, Beatriz; Ruiz-Bronchal, Esther; Torra, Albert; Vila, Miquel et al. DOI: 10.1016/j.ymthe.2018.02.022
PMID: 29611099 Journal: MOLECULAR NEUROBIOLOGY Year: 2018 Reference: Mol Neurobiol. 2018 Sep;55(9):7553-7554. doi: 10.1007/s12035-018-1010-3. Impact factor: Publication type: Letter or abstract Authors: Berkowitz, Laura; Calatayud, Carles; Caldwell, Guy A; Caldwell, Kim A; Carballo-Carbajal, Iria; Consiglio, Antonella; Dalfo, Esther; Ezquerra, Mario; Fernandez-Carasa, Irene; Fernandez-Santiago, Ruben et al. DOI: 10.1007/s12035-018-1010-3
PMID: 28477141 Journal: MOLECULAR NEUROBIOLOGY Year: 2018 Reference: Mol Neurobiol. 2018 Mar;55(3):1861. doi: 10.1007/s12035-017-0553-z. Impact factor: Publication type: Letter or abstract Authors: Del Rio, Jose Antonio; Ferrer, Isidro; Garcia-Aznar, Jose Manuel; Gavin, Rosalina; Hagesawa, Masato; Hervera, Arnau; Masuda-Suzukake, Masami; Pedraz, Lucas; Samitier, Josep; Segura-Feliu, Miriam et al. DOI: 10.1007/s12035-017-0553-z
PMID: 28131189 Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES Year: 2017 Reference: J Neurol Sci. 2017 Feb 15;373:21-22. doi: 10.1016/j.jns.2016.12.011. Epub 2016 Dec 12. Impact factor: Publication type: Letter or abstract Authors: Alvarez-Sabin, Jose; Bejr-Kasem Marco, Helena; Hernandez-Vara, Jorge; Lorenzo-Bosquet, Carles et al. DOI: 10.1016/j.jns.2016.12.011
PMID: 26890313 Journal: Autophagy Year: 2016 Reference: Autophagy. 2016 Mar 3;12(3):612-3. doi: 10.1080/15548627.2016.1143211. Impact factor: Publication type: Paper in international publication Authors: Garcia-Prat, Laura; Martinez-Vicente, Marta; Munoz-Canoves, Pura et al. DOI: 10.1080/15548627.2016.1143211
PMID: 26096669 Journal: NEUROLOGIA Year: 2016 Reference: Neurologia. 2016 May;31(4):231-238. doi: 10.1016/j.nrl.2015.05.002. Epub 2015 Jun 19. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Sabin, J; Casas, M; de Fabregues, O; Hernandez-Vara, J; Marti Andres, G; Ramirez, N; Saez-Francas, N et al. DOI: 10.1016/j.nrl.2015.05.002
PMID: 26347034 Journal: MOVEMENT DISORDERS Year: 2016 Reference: Mov Disord. 2016 Feb;31(2):161-8. doi: 10.1002/mds.26370. Epub 2015 Sep 8. Impact factor: Publication type: Paper in international publication Authors: Bezard, Erwan; Brundin, Patrik; Dehay, Benjamin; Kordower, Jeffrey H; Vila, Miquel et al. DOI: 10.1002/mds.26370
PMID: 26050140 Journal: LANCET NEUROL Year: 2015 Reference: Lancet Neurol. 2015 Aug;14(8):855-66. doi: 10.1016/S1474-4422(15)00006-X. Epub 2015 Jun 3. Impact factor: Publication type: Paper in international publication Authors: Bezard, Erwan; Bourdenx, Mathieu; Dehay, Benjamin; Gorry, Philippe; Hunot, Stephane; Meissner, Wassilios G; Merchant, Kalpana M; Olanow, C Warren; Petsko, Gregory A; Przedborski, Serge et al. DOI: 10.1016/S1474-4422(15)00006-X
PMID: 25843774 Journal: SEMIN CELL DEV BIOL Year: 2015 Reference: Semin Cell Dev Biol. 2015 Apr;40:115-126. doi: 10.1016/j.semcdb.2015.03.005. Epub 2015 Apr 2. Impact factor: Publication type: Review in international publication Authors: Martinez-Vicente, Marta et al. DOI: 10.1016/j.semcdb.2015.03.005
PMID: 25449044 Journal: MOVEMENT DISORD Year: 2015 Reference: Mov Disord. 2015 Feb;30(2):229-37. doi: 10.1002/mds.26077. Epub 2014 Dec 1. Impact factor: Publication type: Paper in international publication Authors: Aguilar, Miquel; Alvarez, Ramiro; Bayes, Angels; Brucke, Thomas; Callen, Antoni; Compta, Yaroslau; De Fabregues, Oriol; Gaig, Carles; Hofeneder, Dominik; Hotter, Anna et al. DOI: 10.1002/mds.26077
PMID: 24390735 Journal: CANCER RESEARCH Year: 2014 Reference: Cancer Res. 2014 Mar 1;74(5):1416-28. doi: 10.1158/0008-5472.CAN-13-1671. Epub 2014 Jan 3. Impact factor: Publication type: Paper in international publication Authors: Cuadros, Thais; de Torres, Ines; Itarte, Emilio; Lopez-Hellin, Joan; Meseguer, Anna; Morote, Juan; Ramon Y Cajal, Santiago; Salcedo, Mayte; Sanchez, Alex; Sarro, Eduard et al. DOI: 10.1158/0008-5472.CAN-13-1671
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PMID: 21045565 Journal: Autophagy Year: 2011 Reference: Autophagy. 2011 Jan;7(1):98-100. Epub 2011 Jan 1. Impact factor: Publication type: Editorail in international publication Authors: ; ; ; ; et al. DOI:
PMID: 20187257 Journal: MOVEMENT DISORDERS Year: 2010 Reference: Mov Disord. 2010;25 Suppl 1:S49-54. Impact factor: Publication type: Paper in international publication Authors: Cuervo, Ana Maria; Martinez-Vicente, Marta; Wong, Esther S P et al. DOI: 10.1002/mds.22718
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PMID: 20305408 Journal: CLINICAL NUCLEAR MEDICINE Year: 2010 Reference: Clin Nucl Med. 2010 Apr;35(4):228-33. Impact factor: Publication type: Paper in international publication Authors: Castell-Conesa, Joan; Cuberas, Gemma; Hernandez, Jorge; Lorenzo, Carles; Miquel, Francesc; Pifarre, Paloma et al. DOI: 10.1097/RLU.0b013e3181d18cb3
The initiative seeks to raise awareness of the disease and promote the well-being of those affected, while fostering empathy and scientific vocations among young people.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Vall d'Hebron has participated in a phase III clinical trial which confirmed the efficacy and safety of subcutaneous infusion of levodopa therapy.
Vall d'Hebron Iniciativa per al Parkinson (VHIP) is a research project aimed at the development of biochemical markers for the early detection of Parkinson's disease. This study is carried out in people at high risk of having this disease, because they carry genetic mutations that predispose to the development of Parkinson's or because they present non-motor symptoms that manifest themselves years before motor symptoms.
