Skip to main content

Neuroradiology

The main characteristic of our group is its multidisciplinary nature, as it is comprised of neuroradiologists, technologists, and a physicist, engineer, and biochemist.

The main objectives of our projects are to gain knowledge about the pathophysiologic mechanisms implicated in several neurological diseases and to evaluate new biomarkers and therapies through the use of qualitative and quantitative magnetic resonance (MR) and computed tomography (CT) techniques, and by applying artificial intelligence tools to create prognostic models. Our focus is on the study of diseases such as multiple sclerosis, epilepsy, neuro-oncology, and stroke.

In addition, because of the experience we have acquired along the years in performing MR studies, we act as a platform for designing MR-based projects, processing images, and conducting quantitative data analysis.

Team

Alex Rovira Cañellas

Alex Rovira Cañellas

Head of group
Neuroradiology
Read more
Margareta Anna Clarke

Margareta Anna Clarke

Research technician
Neuroradiology
Read more
Ana Maria Nieto Montoya

Ana Maria Nieto Montoya

Administration and Management
Neuroradiology
Read more
Andrea De Barros Figueredo

Andrea De Barros Figueredo

Predoctoral researcher
Neuroradiology
Read more
Anna Laura Salerno

Anna Laura Salerno

Predoctoral researcher
Neuroradiology
Read more
Cristina Auger Acosta

Cristina Auger Acosta

Research technician
Neuroradiology
Read more
Alex Rovira Cañellas

Alex Rovira Cañellas

Head of group
Neuroradiology
Read more
Margareta Anna Clarke

Margareta Anna Clarke

Research technician
Neuroradiology
Read more
Ana Maria Nieto Montoya

Ana Maria Nieto Montoya

Administration and Management
Neuroradiology
Read more
Andrea De Barros Figueredo

Andrea De Barros Figueredo

Predoctoral researcher
Neuroradiology
Read more
Anna Laura Salerno

Anna Laura Salerno

Predoctoral researcher
Neuroradiology
Read more
Cristina Auger Acosta

Cristina Auger Acosta

Research technician
Neuroradiology
Read more

Research lines

Advanced quantitative techniques of MR Imaging in the assessment of neurological and neurooncological diseases

The objective of the line is to evaluate the added value of the information provided by quantitative MR techniques, mainly T1 and T2 relaxometry, as well as chemical exchange saturation transfer imaging (CEST) to the study of neurological and neuro-oncological diseases.

IP: Fco. Javier Aymerich Martínez, Alex Rovira Cañellas, Cristina Auger Acosta

Application of magnetic resonance imaging techniques to the study of diabetes

The goal would be to assess the impact of diabetes on brain morphology, integrity and function through the advanced analysis of magnetic resonance images.

IP: Deborah Pareto Onghena, Alex Rovira Cañellas

Application of magnetic resonance imaging techniques to the study of migraine

The goal would be to assess the feasibility and the impact of new magnetic resonance sequences and image analysis tools in the characterization of patients with migraine.

IP: Deborah Pareto Onghena, Alex Rovira Cañellas

Application of magnetic resonance imaging techniques to the study of the pituitary gland

The aim of the line is to evaluate the usefulness of MRI in the study of pituitary tumors, diagnosis and follow-up. The study focuses on the radiological characteristics of tumors that can predict their prognosis. Advances in neuroimaging and behavior of pituitary tumors specifically of macroadenomas are also evaluated, focusing on the radiological characteristics and their potential use with genetic and molecular markers, radiomic ACROFAST project which is a multicenter project.

IP: Silvana Isabel Sarria Estrada

Projects

The Virtual Brain: generative whole-brain models in Multiple Sclerosis

IP: Deborah Pareto Onghena
Collaborators: Gerard Marti Juan, Miriam Izquierdo Sans
Funding agency: ECTRIMS
Funding: 55000
Reference: ECTRIMS-MAGNIMS/2020/MARTI
Duration: 07/06/2021 - 06/06/2022

Incorporación de la caracterización estructuro-funcional medular por resonancia magnética. Aplicación en la esclerosis múltiple.

IP: Deborah Pareto Onghena
Collaborators: Jordi Rio Izquierdo, Elisenda Anglada Clofent, Juan Fco. Corral Gamez, Elena Huerga Núñez
Funding agency: Instituto de Salud Carlos III
Funding: 37510
Reference: PI18/00823
Duration: 01/01/2019 - 30/06/2023

The Virtual Brain: generative whole-brain models in Multiple Sclerosis

IP: Deborah Pareto Onghena
Collaborators: Gerard Marti Juan, Miriam Izquierdo Sans
Funding agency: ECTRIMS
Funding: 55000
Reference: ECTRIMS-MAGNIMS/2020/MARTI
Duration: 07/06/2021 - 06/06/2022

Incorporación de la caracterización estructuro-funcional medular por resonancia magnética. Aplicación en la esclerosis múltiple.

IP: Deborah Pareto Onghena
Collaborators: Jordi Rio Izquierdo, Elisenda Anglada Clofent, Juan Fco. Corral Gamez, Elena Huerga Núñez
Funding agency: Instituto de Salud Carlos III
Funding: 37510
Reference: PI18/00823
Duration: 01/01/2019 - 30/06/2023

Incorporación de la caracterización estructuro-funcional medular por resonancia magnética. Aplicación en la esclerosis múltiple.

IP: Deborah Pareto Onghena
Collaborators: Jordi Rio Izquierdo, Elisenda Anglada Clofent, Juan Fco. Corral Gamez, Elena Huerga Núñez
Funding agency: Instituto de Salud Carlos III
Funding: 37510
Reference: PI18/00823
Duration: 01/01/2019 - 30/06/2023

Iron rims around multiple sclerosis lesions. A new MRI marker of disease activity and progression?

IP: Alex Rovira Cañellas
Collaborators: Miriam Izquierdo Sans
Funding agency: ECTRIMS
Funding: 55000
Reference: ECTRIMS-MAGNIMS/2018/CLARKE
Duration: 01/10/2018 - 30/09/2019

Incorporación de la caracterización estructuro-funcional medular por resonancia magnética. Aplicación en la esclerosis múltiple.

IP: Deborah Pareto Onghena
Collaborators: Jordi Rio Izquierdo, Elisenda Anglada Clofent, Juan Fco. Corral Gamez, Elena Huerga Núñez
Funding agency: Instituto de Salud Carlos III
Funding: 37510
Reference: PI18/00823
Duration: 01/01/2019 - 30/06/2023

Iron rims around multiple sclerosis lesions. A new MRI marker of disease activity and progression?

IP: Alex Rovira Cañellas
Collaborators: Miriam Izquierdo Sans
Funding agency: ECTRIMS
Funding: 55000
Reference: ECTRIMS-MAGNIMS/2018/CLARKE
Duration: 01/10/2018 - 30/09/2019

Automatic detection and analysis of new lesions in serial MR imaging of multiple sclerosis patients

IP: Alex Rovira Cañellas
Collaborators: -
Funding agency: ECTRIMS
Funding: 50000
Reference: ECTRIMS-MAGNIMS_2013-CABEZAS
Duration: 01/05/2014 - 30/04/2015

Automatic detection and analysis of new lesions in serial MR imaging of multiple sclerosis patients

IP: Alex Rovira Cañellas
Collaborators: -
Funding agency: ECTRIMS
Funding: 50000
Reference: ECTRIMS-MAGNIMS_2013-CABEZAS
Duration: 01/05/2014 - 30/04/2015

Red española de esclerosis múltiple (perteneciente a la Red Cien C03/06: Desarrollo de marcadores biológicos y clínicos de la respuesta al tratamiento con Interferón beta en Esclerosis Múltiple.

IP: Alex Rovira Cañellas
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 714
Reference: PI051254
Duration: 01/01/2006 - 31/12/2006

Espectroscopia por RM de protón e imagen de transferencia de magnetización en el estudio de primeros episodios sugestivos de Esclerosis Múltiple.

IP: Juli Alonso Farre
Collaborators: Alex Rovira Cañellas, Mar Tintore Subirana, Xavier Montalban Gairín
Funding agency: Instituto de Salud Carlos III
Funding: 40940
Reference: PI020971
Duration: 06/11/2002 - 31/12/2005

Espectroscopia por RM de protón e imagen de transferencia de magnetización en el estudio de primeros episodios sugestivos de Esclerosis Múltiple.

IP: Juli Alonso Farre
Collaborators: Alex Rovira Cañellas, Mar Tintore Subirana, Xavier Montalban Gairín
Funding agency: Instituto de Salud Carlos III
Funding: 40940
Reference: PI020971
Duration: 06/11/2002 - 31/12/2005

Espectroscopia por RM de protón e imagen de transferencia de magnetización en el estudio de primeros episodios sugestivos de Esclerosis Múltiple.

IP: Juli Alonso Farre
Collaborators: Alex Rovira Cañellas, Mar Tintore Subirana, Xavier Montalban Gairín
Funding agency: Instituto de Salud Carlos III
Funding: 40940
Reference: PI020971
Duration: 06/11/2002 - 31/12/2005

Espectroscopia por RM de protón e imagen de transferencia de magnetización en el estudio de primeros episodios sugestivos de Esclerosis Múltiple.

IP: Juli Alonso Farre
Collaborators: Alex Rovira Cañellas, Mar Tintore Subirana, Xavier Montalban Gairín
Funding agency: Instituto de Salud Carlos III
Funding: 40940
Reference: PI020971
Duration: 06/11/2002 - 31/12/2005

Espectroscopia de protón, transferencia de magnetización y rendimiento cognitivo en la esclerosis múltiple.

IP: Juli Alonso Farre
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 43873.88
Reference: 99/0236
Duration: 01/11/1999 - 01/11/2000

Espectroscopia de protón, transferencia de magnetización y rendimiento cognitivo en la esclerosis múltiple.

IP: Juli Alonso Farre
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 43873.88
Reference: 99/0236
Duration: 01/11/1999 - 01/11/2000

Publications

CSF chitinase 3-like 1 is associated with iron rims in patients with a first demyelinating event.

PMID: 33870790
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jan;28(1):71-81. doi: 10.1177/13524585211010082. Epub 2021 Apr 19.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Pinteac, Rucsanda; Granziera, Cristina; Sastre-Garriga, Jaume; Benkert, Pascal; Auger, Cristina; Kuhle, Jens; Montalban, Xavier; Rovira, Alex; Fissolo, Nicolas; Pareto, Deborah et al.
DOI: 10.1177/13524585211010082

Performance of the 2017 and 2010 Revised McDonald Criteria in Predicting MS Diagnosis After a Clinically Isolated Syndrome: A MAGNIMS Study.

PMID: 34716250
Journal: NEUROLOGY
Year: 2022
Reference: Neurology. 2022 Jan 4;98(1):e1-e14. doi: 10.1212/WNL.0000000000013016. Epub 2021 Oct 29.
Impact factor: 9.91
Publication type: Paper in international publication
Authors: Filippi, Massimo; Preziosa, Paolo; Meani, Alessandro; Costa, Gloria Dalla; Mesaros, Sarlota; Drulovic, Jelena; Ivanovic, Jovana; Rovira, Alex; Tintore, Mar; Montalban, Xavier et al.
DOI: 10.1212/WNL.0000000000013016

Treatment response scoring systems to assess long-term prognosis in self-injectable DMTs relapsing-remitting multiple sclerosis patients.

PMID: 34596743
Journal: JOURNAL OF NEUROLOGY
Year: 2022
Reference: J Neurol. 2022 Jan;269(1):452-459. doi: 10.1007/s00415-021-10823-z. Epub 2021 Oct 1.
Impact factor: 4.849
Publication type: Paper in international publication
Authors: Tur, Carmen; Auger, Cristina; Sastre-Garriga, Jaume; Montalban, Xavier; Cobo, Alvaro; Nos, Carlos; Arrambide, Georgina; Castillo, Joaquim; Rio, Jordi; Gasperini, Claudio et al.
DOI: 10.1007/s00415-021-10823-z

Herpes simplex encephalitis in the context of immune checkpoint inhibitors: a complex interplay.

PMID: 34988947
Journal: ACTA NEUROLOGICA BELGICA
Year: 2022
Reference: Acta Neurol Belg. 2022 Jun;122(3):823-825. doi: 10.1007/s13760-021-01864-2. Epub 2022 Jan 6.
Impact factor: 2.396
Publication type: Letter or abstract
Authors: Lallana, Sofia; Sanchez-Tejerina, Daniel; Auger, Cristina; Callejo, Ana; Rio, Jordi; Cobo-Calvo, Alvaro et al.
DOI: 10.1007/s13760-021-01864-2

Assessment of automatic decision-support systems for detecting active T2 lesions in multiple sclerosis patients.

PMID: 34859704
Journal: Multiple Sclerosis Journal
Year: 2021
Reference: Mult Scler. 2021 Dec 3:13524585211061339. doi: 10.1177/13524585211061339.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Rovira, Alex, Corral, Juan Francisco, Auger, Cristina, Valverde, Sergi, Vidal-Jordana, Angela, Ng Wong, Yiken Karelys, Tintore, Mar, Pareto, Deborah, Aymerich, Francesc Xavier, Montalban, Xavier et al.
DOI: 10.1177/13524585211061339

MRI findings in cervical spondylotic myelopathy with gadolinium enhancement: Review of seven cases.

PMID: 33841903
Journal: BJR case reports
Year: 2021
Reference: BJR Case Rep. 2021 Jan 5;7(2):20200133. doi: 10.1259/bjrcr.20200133. eCollection 2021 Apr 1.
Impact factor: 0
Publication type: Letter or abstract
Authors: Pessini Ferreira, Lucas Maria, Auger, Cristina, Kortazar Zubizarreta, Izaro, Gonzalez Chinchon, Gonzalo, Herrera, Isabel, Pla, Albert, de Barros, Andrea, Tortajada, Carlos, Rovira, Alex et al.
DOI: 10.1259/bjrcr.20200133

Value of 3T Susceptibility-Weighted Imaging in the Diagnosis of Multiple Sclerosis.

PMID: 32439639
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2020
Reference: AJNR Am J Neuroradiol. 2020 Jun;41(6):1001-1008. doi: 10.3174/ajnr.A6547. Epub 2020 May 21.
Impact factor: 3.381
Publication type: Paper in international publication
Authors: Tintore, M, Sastre-Garriga, J, Auger, C, Montalban, X, Evangelou, N, Rovira, A, Cappelle, S, Crescenzo, F, Alberich, M, Arrambide, G et al.
DOI: 10.3174/ajnr.A6547

Ratio of T1-Weighted to T2-Weighted Signal Intensity as a Measure of Tissue Integrity: Comparison with Magnetization Transfer Ratio in Patients with Multiple Sclerosis.

PMID: 32139431
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2020
Reference: AJNR Am J Neuroradiol. 2020 Mar;41(3):461-463. doi: 10.3174/ajnr.A6481. Epub 2020 Mar 5.
Impact factor: 3.381
Publication type: Paper in international publication
Authors: Pareto, D, Garcia-Vidal, A, Alberich, M, Auger, C, Montalban, X, Tintore, M, Sastre-Garriga, J, Rovira, A et al.
DOI: 10.3174/ajnr.A6481

Blog

News

Els doctors Xavier Montalban, Àlex Rovira i Mar Tintoré han estat reconeguts en la categoria de Neurociències i Comportament, i el doctor Jordi Rello en la categoria Interdisciplinària.

The program, promoted by Biocat in collaboration with CIMIT (Boston), is aimed at entrepreneurs in the process of bringing their technology to market in the next few years.

Job offers

Researcher Technician MRI analysis.
Start date:
30/11/2022
End date:
14/12/2022
Document: Download
Postdoctoral Researcher-in MRI brain imaging.
Start date:
07/10/2022
End date:
01/12/2022
Document: Download
Postdoctoral - Magnetic Resonance and Neuroradiology.
Start date:
04/10/2021
End date:
18/10/2021
Document: Download