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Neuroradiology

The main characteristic of our group is its multidisciplinary nature, as it is comprised of neuroradiologists, technologists, and a physicist, engineer, and biochemist.

The main objectives of our projects are to gain knowledge about the pathophysiologic mechanisms implicated in several neurological diseases and to evaluate new biomarkers and therapies through the use of qualitative and quantitative magnetic resonance (MR) and computed tomography (CT) techniques, and by applying artificial intelligence tools to create prognostic models. Our focus is on the study of diseases such as multiple sclerosis, epilepsy, neuro-oncology, and stroke.

In addition, because of the experience we have acquired along the years in performing MR studies, we act as a platform for designing MR-based projects, processing images, and conducting quantitative data analysis.

Team

Alex Rovira Cañellas

Alex Rovira Cañellas

Head of group
Neuroradiology
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Alberich Jordà, Manel

Alberich Jordà, Manel

Research technician
Neuroradiology
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Margareta Anna Clarke

Margareta Anna Clarke

Research technician
Neuroradiology
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Sofía María Sceppacuercia

Sofía María Sceppacuercia

Predoctoral researcher
Neuroradiology
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Ana Maria Nieto Montoya

Ana Maria Nieto Montoya

Administration and Management
Neuroradiology
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Andrea De Barros Figueredo

Andrea De Barros Figueredo

Predoctoral researcher
Neuroradiology
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Alex Rovira Cañellas

Alex Rovira Cañellas

Head of group
Neuroradiology
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Alberich Jordà, Manel

Alberich Jordà, Manel

Research technician
Neuroradiology
Read more
Margareta Anna Clarke

Margareta Anna Clarke

Research technician
Neuroradiology
Read more
Sofía María Sceppacuercia

Sofía María Sceppacuercia

Predoctoral researcher
Neuroradiology
Read more
Ana Maria Nieto Montoya

Ana Maria Nieto Montoya

Administration and Management
Neuroradiology
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Andrea De Barros Figueredo

Andrea De Barros Figueredo

Predoctoral researcher
Neuroradiology
Read more

Research lines

Advanced quantitative techniques of MR Imaging in the assessment of neurological and neurooncological diseases

The objective of the line is to evaluate the added value of the information provided by quantitative MR techniques, mainly T1 and T2 relaxometry, as well as chemical exchange saturation transfer imaging (CEST) to the study of neurological and neuro-oncological diseases.

IP: Aymerich Martínez, Fco. Javier, Rovira Cañellas, Alex, Auger Acosta, Cristina

Application of magnetic resonance imaging techniques to the study of diabetes

The goal would be to assess the impact of diabetes on brain morphology, integrity and function through the advanced analysis of magnetic resonance images.

IP: Pareto Onghena, Deborah, Rovira Cañellas, Alex

Application of magnetic resonance imaging techniques to the study of migraine

The goal would be to assess the feasibility and the impact of new magnetic resonance sequences and image analysis tools in the characterization of patients with migraine.

IP: Pareto Onghena, Deborah, Rovira Cañellas, Alex

Application of magnetic resonance imaging techniques to the study of the pituitary gland

The aim of the line is to evaluate the usefulness of MRI in the study of pituitary tumors, diagnosis and follow-up. The study focuses on the radiological characteristics of tumors that can predict their prognosis. Advances in neuroimaging and behavior of pituitary tumors specifically of macroadenomas are also evaluated, focusing on the radiological characteristics and their potential use with genetic and molecular markers, radiomic ACROFAST project which is a multicenter project.

IP: Sarria Estrada, Silvana Isabel

Projects

Caracterización de la DIScapacidad y la COgnición en sujetos con Esclerosis múltiple a partir de secuencias de Resonancia magnética convencional (DISCOvER).

IP: Pareto Onghena, Deborah
Collaborators: Galán Cartaña, Ingrid, Corral Gamez, Juan Fco., Eixarch Ahufinger, Herena, Arevalo Navines, M Jesus, De Barros Figueredo, Andrea, Mongay Ochoa, Neus, Colangelo , Giorgio
Funding agency: Instituto de Salud Carlos III
Funding: 87120
Reference: PI22/01709
Duration: 01/01/2023 - 31/12/2025

ResEM Project - Desarrollo de un modelo global de reserva funcional y estructural del sistema nervioso central en esclerosis múltiple

IP: Sastre Garriga, Jaume
Collaborators: Auger Acosta, Cristina, Santoyo Medina, Carme, Arevalo Navines, M Jesus, Montalban Gairín, Xavier, Gutiérrez Ruiz, Lucía, Mongay Ochoa, Neus
Funding agency: Instituto de Salud Carlos III
Funding: 157300
Reference: PI22/00750
Duration: 01/01/2023 - 31/12/2025

Caracterización estructural y funcional de la vía visual anterior en pacientes con esclerosis múltiple temprana (VISIONEM).

IP: Vidal Jordana, Angela
Collaborators: Moncho Rodríguez, Dulce María, Rovira Cañellas, Alex, Mongay Ochoa, Neus, Castillo Justribo, Joaquin, Caracterización estructural y funcional de la vía visual anterior en pacientes con esclerosis múltiple temprana (VISIONEM)., Cabello , Sergio
Funding agency: Instituto de Salud Carlos III
Funding: 48400
Reference: PI22/01589
Duration: 01/01/2023 - 31/12/2025

Impacto de la cirugía bariátrica en la hemodinámica portal en pacientes con obesidad mórbida y NAFLD. Estudio HEYMDAL.

IP: Vilallonga Puy, Ramón
Collaborators: Mercedes Pérez Lafuente, Roson Gradaille, Nuria , Puente Ramo, Laura, Gonzalez Junyent, Carla, Comas Martínez, Marta, Rojano Toimil, Alba, Arturo Cirera De Tudela, Impacto de la cirugía bariátrica en la hemodinámica portal en pacientes con obesidad mórbida y NAFLD. Estudio HEYMDAL., Jesus Manuel Rivera Esteban, Impacto de la cirugía bariátrica en la hemodinámica portal en pacientes con obesidad mórbida y NAFLD. Estudio HEYMDAL.
Funding agency: Instituto de Salud Carlos III
Funding: 171820
Reference: PI22/00880
Duration: 01/01/2023 - 31/12/2025

Publications

Imaging of Drug-Related Vasculopathy.

PMID: 37951697
Journal: NEUROIMAGING CLINICS OF NORTH AMERICA
Year: 2024
Reference: Neuroimaging Clin N Am. 2024 Feb;34(1):113-128. doi: 10.1016/j.nic.2023.07.003. Epub 2023 Oct 10.
Impact factor:
Publication type: Paper in international publication
Authors: Puac-Polanco, Paulo; Rivas Rodriguez, Francisco; Rovira, Alex; Shah, Lubdha M; Torres, Carlos; Wiggins, Richard H et al.
DOI: 10.1016/j.nic.2023.07.003

Deciphering multiple sclerosis disability with deep learning attention maps on clinical MRI.

PMID: 36940621
Journal: NeuroImage-Clinical
Year: 2023
Reference: Neuroimage Clin. 2023;38:103376. doi: 10.1016/j.nicl.2023.103376. Epub 2023 Mar 15.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, Manel; Arrambide, Georgina; Auger, Cristina; Carbonell-Mirabent, Pere; Castillo, Joaquin; Cobo-Calvo, Alvaro; Coll, Llucia; Coll, Llucia; Comabella, Manuel; Galan, Ingrid et al.
DOI: 10.1016/j.nicl.2023.103376

Clinical Reasoning: An 82-Year-Old Woman With Subacute Ophthalmoparesis and Ataxia.

PMID: 36990717
Journal: NEUROLOGY
Year: 2023
Reference: Neurology. 2023 Aug 1;101(5):e570-e575. doi: 10.1212/WNL.0000000000207246. Epub 2023 Mar 29.
Impact factor:
Publication type: Letter or abstract
Authors: Auger, Cristina; Baucells, Andres; Gonzalez, Victoria; Llaurado, Arnau; Rodrigo-Gisbert, Marc et al.
DOI: 10.1212/WNL.0000000000207246

[Rapidly progressive intracranial large artery aterosclerosis, a rare stroke etiology].

PMID: 37046396
Journal: REVISTA DE NEUROLOGIA
Year: 2023
Reference: Rev Neurol. 2023 Apr 16;76(8):273-275. doi: 10.33588/rn.7608.2022328.
Impact factor:
Publication type: Letter or abstract
Authors: Anton-Jimenez, A; Martinez-Saez, E; Rovira, A; Sarria-Estrada, S; Tortajada-Bustelo, J C et al.
DOI: 10.33588/rn.7608.2022328

Hybrid neurofibroma/schwannoma of the orbit.

PMID: 37061243
Journal: Revista espanola de patologia
Year: 2023
Reference: Rev Esp Patol. 2023 Apr-Jun;56(2):140-143. doi: 10.1016/j.patol.2022.03.002. Epub 2022 Jun 15.
Impact factor:
Publication type: Letter or abstract
Authors: Arcediano, Miguel Angel; Dinares, Carme; Dinares, Carme; Naranjo, Lourdes; Ramon Y Cajal, Santiago; Ramon Y Cajal, Santiago; Romagosa, Cleofe; Romagosa, Cleofe; Salazar-Huayna, Lourdes; Siurana, Sahyly et al.
DOI: 10.1016/j.patol.2022.03.002

CSF chitinase 3-like 1 is associated with iron rims in patients with a first demyelinating event.

PMID: 33870790
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jan;28(1):71-81. doi: 10.1177/13524585211010082. Epub 2021 Apr 19.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Pinteac, Rucsanda; Granziera, Cristina; Sastre-Garriga, Jaume; Benkert, Pascal; Auger, Cristina; Kuhle, Jens; Montalban, Xavier; Rovira, Alex; Fissolo, Nicolas; Pareto, Deborah et al.
DOI: 10.1177/13524585211010082

Performance of the 2017 and 2010 Revised McDonald Criteria in Predicting MS Diagnosis After a Clinically Isolated Syndrome: A MAGNIMS Study.

PMID: 34716250
Journal: NEUROLOGY
Year: 2022
Reference: Neurology. 2022 Jan 4;98(1):e1-e14. doi: 10.1212/WNL.0000000000013016. Epub 2021 Oct 29.
Impact factor: 9.91
Publication type: Paper in international publication
Authors: Filippi, Massimo; Preziosa, Paolo; Meani, Alessandro; Costa, Gloria Dalla; Mesaros, Sarlota; Drulovic, Jelena; Ivanovic, Jovana; Rovira, Alex; Tintore, Mar; Montalban, Xavier et al.
DOI: 10.1212/WNL.0000000000013016

Treatment response scoring systems to assess long-term prognosis in self-injectable DMTs relapsing-remitting multiple sclerosis patients.

PMID: 34596743
Journal: JOURNAL OF NEUROLOGY
Year: 2022
Reference: J Neurol. 2022 Jan;269(1):452-459. doi: 10.1007/s00415-021-10823-z. Epub 2021 Oct 1.
Impact factor: 4.849
Publication type: Paper in international publication
Authors: Tur, Carmen; Auger, Cristina; Sastre-Garriga, Jaume; Montalban, Xavier; Cobo, Alvaro; Nos, Carlos; Arrambide, Georgina; Castillo, Joaquim; Rio, Jordi; Gasperini, Claudio et al.
DOI: 10.1007/s00415-021-10823-z

Herpes simplex encephalitis in the context of immune checkpoint inhibitors: a complex interplay.

PMID: 34988947
Journal: ACTA NEUROLOGICA BELGICA
Year: 2022
Reference: Acta Neurol Belg. 2022 Jun;122(3):823-825. doi: 10.1007/s13760-021-01864-2. Epub 2022 Jan 6.
Impact factor: 2.396
Publication type: Letter or abstract
Authors: Lallana, Sofia; Sanchez-Tejerina, Daniel; Auger, Cristina; Callejo, Ana; Rio, Jordi; Cobo-Calvo, Alvaro et al.
DOI: 10.1007/s13760-021-01864-2

Assessment of automatic decision-support systems for detecting active T2 lesions in multiple sclerosis patients.

PMID: 34859704
Journal: Multiple Sclerosis Journal
Year: 2021
Reference: Mult Scler. 2021 Dec 3:13524585211061339. doi: 10.1177/13524585211061339.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Rovira, Alex, Corral, Juan Francisco, Auger, Cristina, Valverde, Sergi, Vidal-Jordana, Angela, Ng Wong, Yiken Karelys, Tintore, Mar, Pareto, Deborah, Aymerich, Francesc Xavier, Montalban, Xavier et al.
DOI: 10.1177/13524585211061339

MRI findings in cervical spondylotic myelopathy with gadolinium enhancement: Review of seven cases.

PMID: 33841903
Journal: BJR case reports
Year: 2021
Reference: BJR Case Rep. 2021 Jan 5;7(2):20200133. doi: 10.1259/bjrcr.20200133. eCollection 2021 Apr 1.
Impact factor: 0
Publication type: Letter or abstract
Authors: Pessini Ferreira, Lucas Maria, Auger, Cristina, Kortazar Zubizarreta, Izaro, Gonzalez Chinchon, Gonzalo, Herrera, Isabel, Pla, Albert, de Barros, Andrea, Tortajada, Carlos, Rovira, Alex et al.
DOI: 10.1259/bjrcr.20200133

Value of 3T Susceptibility-Weighted Imaging in the Diagnosis of Multiple Sclerosis.

PMID: 32439639
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2020
Reference: AJNR Am J Neuroradiol. 2020 Jun;41(6):1001-1008. doi: 10.3174/ajnr.A6547. Epub 2020 May 21.
Impact factor: 3.381
Publication type: Paper in international publication
Authors: Tintore, M, Sastre-Garriga, J, Auger, C, Montalban, X, Evangelou, N, Rovira, A, Cappelle, S, Crescenzo, F, Alberich, M, Arrambide, G et al.
DOI: 10.3174/ajnr.A6547

Ratio of T1-Weighted to T2-Weighted Signal Intensity as a Measure of Tissue Integrity: Comparison with Magnetization Transfer Ratio in Patients with Multiple Sclerosis.

PMID: 32139431
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2020
Reference: AJNR Am J Neuroradiol. 2020 Mar;41(3):461-463. doi: 10.3174/ajnr.A6481. Epub 2020 Mar 5.
Impact factor: 3.381
Publication type: Paper in international publication
Authors: Pareto, D, Garcia-Vidal, A, Alberich, M, Auger, C, Montalban, X, Tintore, M, Sastre-Garriga, J, Rovira, A et al.
DOI: 10.3174/ajnr.A6481

Thesis

Neuroimagen morfológica y funcional en epilepsia

PhD student: Silvana Isabel Sarria Estrada
Director/s: Jordi Giralt López de Sagred
University: Universidad Autònoma de Barcelona
Year: 2021

Blog

News

Els doctors Xavier Montalban, Àlex Rovira i Mar Tintoré han estat reconeguts en la categoria de Neurociències i Comportament, i el doctor Jordi Rello en la categoria Interdisciplinària.

The program, promoted by Biocat in collaboration with CIMIT (Boston), is aimed at entrepreneurs in the process of bringing their technology to market in the next few years.

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