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Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Publications

Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations.

PMID: 34570994
Journal: Lancet Respiratory Medicine
Year: 2022
Reference: Lancet Respir Med. 2022 Mar;10(3):298-306. doi: 10.1016/S2213-2600(21)00277-0. Epub 2021 Sep 24.
Impact factor: 30.7
Publication type: Review in international publication
Authors: Welte, Tobias, De Soyza, Anthony, Dimakou, Katerina E, Elborn, Stuart J, Feldman, Charles, Tiddens, Harm, Haworth, Charles S, Hill, Adam T, Loebinger, Michael R, Martinez-Garcia, Miguel Angel et al.
DOI: 10.1016/S2213-2600(21)00277-0

Long-Term Risk of Mortality Associated with Isolation of Pseudomonas aeruginosa in COPD: A Systematic Review and Meta-Analysis.

PMID: 35210766
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2022
Reference: Int J Chron Obstruct Pulmon Dis. 2022 Feb 16;17:371-382. doi: 10.2147/COPD.S346294. eCollection 2022.
Impact factor: 3.355
Publication type: Review in international publication
Authors: Martinez-Garcia, Miguel Angel, Rigau, David, Barrecheguren, Miriam, Garcia-Ortega, Alberto, Nunez, Alexa, Oscullo Yepez, Grace, Miravitlles, Marc et al.
DOI: 10.2147/COPD.S346294

Management and prognosis of HIV-associated pulmonary arterial hypertension: 20 years of evidence from the REHAP registry.

PMID: 35184348
Journal: JOURNAL OF INTERNAL MEDICINE
Year: 2022
Reference: J Intern Med. 2022 Jul;292(1):116-126. doi: 10.1111/joim.13468. Epub 2022 Mar 25.
Impact factor: 8.989
Publication type: Paper in international publication
Authors: Lazaro, Salvador Maria, Rodriguez-Padial, Luis, Soto Abanades, Clara, Cruz Utrilla, Alejandro, Barbera, Mir Joan Albert, Lopez-Meseguer, Manuel, Segovia, Cubero Javier, Samper, Gustavo Juan, Blanco, Vich Isabel, Escribano-Subias, Pilar et al.
DOI: 10.1111/joim.13468

Safety and Effectiveness of Isavuconazole Treatment for Fungal Infections in Solid Organ Transplant Recipients (ISASOT Study).

PMID: 35171022
Journal: Microbiology Spectrum
Year: 2022
Reference: Microbiol Spectr. 2022 Feb 23;10(1):e0178421. doi: 10.1128/spectrum.01784-21. Epub 2022 Feb 16.
Impact factor: 7.171
Publication type: Paper in international publication
Authors: Monforte, Arnau, Los-Arcos, Ibai, Martin-Gomez, Maria Teresa, Campany-Herrero, David, Sacanell, Judith, Berastegui, Cristina, Marquez-Algaba, Ester, Sempere, Abiu, Nuvials, Xavier, Castells, Lluis et al.
DOI: 10.1128/spectrum.01784-21

Long-term Effect of CPAP Treatment on Cardiovascular Events in Patients With Resistant Hypertension and Sleep Apnea. Data From the HIPARCO-2 Study.

PMID: 32029279
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Mar;57(3):165-171. doi: 10.1016/j.arbres.2019.12.006. Epub 2020 Feb 3.
Impact factor: 4.872
Publication type: Paper in national publication
Authors: Martinez-Garcia, Miguel-Angel, Navarro-Soriano, Cristina, Sanchez-de-la-Torre, Manuel, Caballero-Eraso, Candela, Lloberes, Patricia, Cambriles, Trinidad Diaz, Somoza, Maria, Masa, Juan F, Gonzalez, Monica, Manas, Eva et al.
DOI: 10.1016/j.arbres.2019.12.006

Portopulmonary hypertension: prognosis and management in the current treatment era. Results from the REHAP Registry.

PMID: 31943676
Journal: INTERNAL MEDICINE JOURNAL
Year: 2021
Reference: Intern Med J. 2021 Mar;51(3):355-365. doi: 10.1111/imj.14751.
Impact factor: 2.048
Publication type: Paper in international publication
Authors: Alvarez Vega, P, Barbera, J A, Barrios Garrido-Lestache, E, Bedate, P, Blanco, I, Cadenas, S, Cifrian, J M, Del Cerro, M J, Domingo, J A, Dos, L et al.
DOI: 10.1111/imj.14751

Nebulized micafungin treatment for Scopulariopsis/Microascus tracheobronchitis in lung transplant recipients.

PMID: 33722884
Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Year: 2021
Reference: Antimicrob Agents Chemother. 2021 May 18;65(6). pii: AAC.02174-20. doi: 10.1128/AAC.02174-20. Print 2021 May 18.
Impact factor: 5.191
Publication type: Paper in international publication
Authors: Los-Arcos, Ibai, Berastegui, Cristina, Martin-Gomez, Maria Teresa, Grau, Santiago, Campany-Herrero, David, Deu, Maria, Sacanell, Judith, Campillo, Nuria, Bravo, Carles, Len, Oscar et al.
DOI: 10.1128/AAC.02174-20

Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial.

PMID: 33357499
Journal: Lancet Respiratory Medicine
Year: 2021
Reference: Lancet Respir Med. 2021 Mar;9(3):260-274. doi: 10.1016/S2213-2600(20)30414-8. Epub 2020 Dec 22.
Impact factor: 30.7
Publication type: Paper in international publication
Authors: Beghe, Bianca, Harrison, Tim W, Chanez, Pascal, Menzella, Francesco, Canonica, Giorgio Walter, Louis, Renaud, Cosio, Borja G, Lugogo, Njira L, Mohan, Arjun, Burden, Annie et al.
DOI: 10.1016/S2213-2600(20)30414-8

Addition of Rituximab to Oral Corticosteroids in the Treatment of Chronic Hypersensitivity Pneumonitis.

PMID: 31506211
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2020
Reference: Arch Bronconeumol. 2020 Apr;56(4):254-256. doi: 10.1016/j.arbres.2019.07.013. Epub 2019 Sep 8.
Impact factor: 4.957
Publication type: Paper in national publication
Authors: Morell, Ferran, Ojanguren, Inigo, Villar, Ana, Ramon, Maria Antonia, Munoz, Xavier, Cruz, Maria Jesus et al.
DOI: 10.1016/j.arbres.2019.07.013

The validity of the Canadian clinical scores for occupational asthma in European populations.

PMID: 32242942
Journal: ALLERGY
Year: 2020
Reference: Allergy. 2020 Aug;75(8). doi: 10.1111/all.14294. Epub 2020 May 4.
Impact factor: 8.706
Publication type: Letter whit IF
Authors: Suarthana, Eva, Taghiakbari, Mahsa, Saha-Chaudhuri, Paramita, Rifflart, Catherine, Suojalehto, Hille, Holtta, Pirjo, Walusiak-Skorupa, Jolanta, Wiszniewska, Marta, Munoz, Xavier, Romero-Mesones, Christian et al.
DOI: 10.1111/all.14294

Cost-effectiveness of positive airway pressure modalities in obesity hypoventilation syndrome with severe obstructive sleep apnoea.

PMID: 32217780
Journal: THORAX
Year: 2020
Reference: Thorax. 2020 Jun;75(6):459-467. doi: 10.1136/thoraxjnl-2019-213622. Epub 2020 Mar 26.
Impact factor: 8.834
Publication type: Paper in international publication
Authors: Masa, Juan F, Mokhlesi, Babak, Benitez, Ivan, Gomez de Terreros Caro, Francisco Javier, Sanchez-Quiroga, M-Angeles, Romero, Auxiliadora, Caballero, Candela, Alonso-Alvarez, Maria Luz, Ordax-Carbajo, Estrella, Gomez-Garcia, Teresa et al.
DOI: 10.1136/thoraxjnl-2019-213622

Peribronchovascular Emphysema. The Macklin Effect.

PMID: 32201012
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2020
Reference: Arch Bronconeumol. 2020 Mar 19. pii: S0300-2896(20)30060-0. doi: 10.1016/j.arbres.2020.02.002.
Impact factor: 4.957
Publication type: Paper in national publication
Authors: Ferreiro, Antia, Granados, Galo, Villar, Ana et al.
DOI: 10.1016/j.arbres.2020.02.002

Bronchiectasis in severe asthma: a distinct phenotype?

PMID: 30461531
Journal: CURRENT OPINION IN PULMONARY MEDICINE
Year: 2019
Reference: Curr Opin Pulm Med. 2019 Jan;25(1):71-78. doi: 10.1097/MCP.0000000000000542.
Impact factor: 2.541
Publication type: Paper in international publication
Authors: Perez-Miranda, Javier, Traversi, Letizia, Polverino, Eva et al.
DOI: 10.1097/MCP.0000000000000542

EXPRESS: Proximal pulmonary arterial wall disease in patients with persistent pulmonary hypertension after successful left-sided valve replacement according to the hemodynamic phenotype.

PMID: 30430894
Journal: Pulmonary Circulation
Year: 2019
Reference: Pulm Circ. 2019 Jan-Mar;9(1):2045894018816972. doi: 10.1177/2045894018816972. Epub 2018 Nov 15.
Impact factor: 2.075
Publication type: Paper in international publication
Authors: Domingo, Enric, Grignola, Juan, Trujillo, Pedro, Aguilar, Rio, Roman, Antonio et al.
DOI: 10.1177/2045894018816972

Procalcitonin accurately predicts lung transplant adults with low risk of pulmonary graft dysfunction and intensive care mortality.

PMID: 29112904
Journal: JOURNAL OF CRITICAL CARE
Year: 2018
Reference: J Crit Care. 2018 Apr;44:142-147. doi: 10.1016/j.jcrc.2017.10.047. Epub 2017 Oct 31.
Impact factor: 2.872
Publication type: Paper in international publication
Authors: Rello, Jordi, Roman, Antonio, Moyano, Silvia, Sandiumenge, Alberto, Pont, Teresa, Mazo, Cristopher, Borgatta, Barbara et al.
DOI: 10.1016/j.jcrc.2017.10.047

Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Summary of Recommendations.

PMID: 29472044
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2018
Reference: Arch Bronconeumol. 2018 Apr;54(4):205-215. doi: 10.1016/j.arbres.2017.11.014. Epub 2018 Feb 19.
Impact factor: 2.633
Publication type: Paper in national publication
Authors: Perez-Penate, Gregorio, Sala, Ernest, Escribano, Pilar, Otero, Isabel, Lopez-Reyes, Raquel, Otero, Remedios, Blanco, Isabel, Barbera, Joan Albert, Roman, Antonio, Gomez-Sanchez, Miguel Angel et al.
DOI: 10.1016/j.arbres.2017.11.014

Spanish Guidelines on the Evaluation and Diagnosis of Bronchiectasis in Adults.

PMID: 29128130
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2018
Reference: Arch Bronconeumol. 2018 Feb;54(2):79-87. doi: 10.1016/j.arbres.2017.07.015. Epub 2017 Nov 9.
Impact factor: 2.633
Publication type: Paper in national publication
Authors: Polverino, Eva, de Gracia, Javier, Prados, Concepcion, Vendrell, Montserrat, Canton, Rafael, Blanco, Marina, de la Rosa, David, Martinez-Garcia, Miguel Angel, Maiz, Luis, Olveira, Casilda et al.
DOI: 10.1016/j.arbres.2017.07.015

Spanish Guidelines on Treatment of Bronchiectasis in Adults.

PMID: 29128129
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2018
Reference: Arch Bronconeumol. 2018 Feb;54(2):88-98. doi: 10.1016/j.arbres.2017.07.016. Epub 2017 Nov 9.
Impact factor: 2.633
Publication type: Paper in national publication
Authors: Martinez-Garcia, Miguel Angel, Maiz, Luis, Olveira, Casilda, Giron, Rosa Maria, de la Rosa, David, Blanco, Marina, Canton, Rafael, Vendrell, Montserrat, Polverino, Eva, de Gracia, Javier et al.
DOI: 10.1016/j.arbres.2017.07.016

Adaptive Servoventilation Device Software in the Assessment of Residual Respiratory Events in Patients With Central or Complex Apnoeas.

PMID: 28209445
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2017
Reference: Arch Bronconeumol. 2017 Aug;53(8):455-457. doi: 10.1016/j.arbres.2016.11.026. Epub 2017 Feb 13.
Impact factor: 2.979
Publication type: Paper in national publication
Authors: Silveira, Maria-Guadalupe, Sampol, Gabriel, Cambrodi, Roser, Ferre, Alex, Lloberes, Patricia et al.
DOI: 10.1016/j.arbres.2016.11.026

Etiology of Bronchiectasis in a Cohort of 2047 Patients. An Analysis of the Spanish Historical Bronchiectasis Registry.

PMID: 28118936
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2017
Reference: Arch Bronconeumol. 2017 Jul;53(7):366-374. doi: 10.1016/j.arbres.2016.12.003. Epub 2017 Jan 21.
Impact factor: 2.979
Publication type: Paper in national publication
Authors: Olveira, Casilda, Padilla, Alicia, Martinez-Garcia, Miguel-Angel, de la Rosa, David, Giron, Rosa-Maria, Vendrell, Montserrat, Maiz, Luis, Borderias, Luis, Polverino, Eva, Martinez-Moragon, Eva et al.
DOI: 10.1016/j.arbres.2016.12.003

Predicting high risk of exacerbations in bronchiectasis: the E-FACED score.

PMID: 28182132
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2017
Reference: Int J Chron Obstruct Pulmon Dis. 2017 Jan 18;12:275-284. doi: 10.2147/COPD.S121943. eCollection 2017.
Impact factor: 3.157
Publication type: Paper in international publication
Authors: Fernandes De Figueiredo, M, Arancibia, F, Rached, S Z, Lundgren, F L, Corso Pereira, M, Prados-Sanchez, C, Martinez-Garcia, M A, Athanazio, R A, Giron, R, Maiz-Carro, L et al.
DOI: 10.2147/COPD.S121943

Safety and efficacy of the C-Tb skin test to diagnose Mycobacterium tuberculosis infection, compared with an interferon gamma release assay and the tuberculin skin test: a phase 3, double-blind, randomised, controlled trial.

PMID: 28159608
Journal: Lancet Respiratory Medicine
Year: 2017
Reference: Lancet Respir Med. 2017 Apr;5(4):259-268. doi: 10.1016/S2213-2600(16)30436-2. Epub 2017 Feb 1.
Impact factor: 19.287
Publication type: Paper in international publication
Authors: Orcau, Angels, Andersen, Peter, Cayla, Joan A, Roldan, Llanos, Miro, Jose M, Moreno, Antonio, Ruhwald, Morten, Aggerbeck, Henrik, Gallardo, Rafael Vazquez, Hoff, Soren T et al.
DOI: 10.1016/S2213-2600(16)30436-2

Future Directions in Lung Transplant.

PMID: 24360986
Journal: ARCH BRONCONEUMOL
Year: 2014
Reference: Arch Bronconeumol. 2014 Jan;50(1):1-2. doi: 10.1016/j.arbres.2013.11.011. Epub 2013 Dec 19.
Impact factor: 1.816
Publication type: Editorial in national publication
Authors: Roman, Antonio, Sole, Joan et al.
DOI: 10.1016/j.arbres.2013.11.011

Pharmacokinetic study of conversion from tacrolimus twice-daily to tacrolimus once-daily in stable lung transplantation.

PMID: 24492423
Journal: TRANSPLANTATION
Year: 2014
Reference: Transplantation. 2014 Feb 15;97(3):358-62. doi: 10.1097/01.TP.0000435699.69266.66.
Impact factor: 3.535
Publication type: Paper in international publication
Authors: Mendez, Alejandra, Berastegui, Cristina, Lopez-Meseguer, Manuel, Monforte, Victor, Bravo, Carlos, Blanco, Albert, Camos, Silvia, Pou, Leonor, Roman, Antonio et al.
DOI: 10.1097/01.TP.0000435699.69266.66

Successful pregnancy in a patient with pulmonary hypertension associated with mixed collagen vascular disease.

PMID: 24456447
Journal: J OBSTET GYNAECOL
Year: 2014
Reference: J Obstet Gynaecol. 2014 Feb;34(2):191. doi: 10.3109/01443615.2012.706663.
Impact factor: 0.604
Publication type: Paper in international publication
Authors: Goya, M, Meseguer, M L, Merced, C, Suy, A, Monforte, V, Domingo, E, Cabero, L, Roman, A et al.
DOI: 10.3109/01443615.2012.706663

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Vall d'Hebron participated in the study in which more than half of the patients who received treatment with bacteriophages experienced significant improvements

La recerca és fonamental per contrarestar els efectes de la pol·lució, que segons l’AEMPS, va ser la causa de més de 300.000 morts prematures a la UE el 2020.

Pulmonary hypertension is a risk factor for patients who need surgery and, therefore, defining strategies for its management is important to allow a favorable clinical evolution.

Job offers

Group of Research in Pneumology - Predoctoral fellow
Start date:
20/12/2018
End date:
27/12/2018
Document: Download
Predoctoral Researcher
Start date:
10/12/2018
End date:
16/12/2018
Document: Download
NURSE - Group of Pneumology
Start date:
26/11/2018
End date:
03/12/2018
Document: Download

EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.