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Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Publications

Cluster-derived obstructive sleep apnea phenotypes and outcomes at five year follow-up.

PMID: 34569926
Journal: Journal of Clinical Sleep Medicine
Year: 2022
Reference: J Clin Sleep Med. 2022 Feb 1;18(2):597-607. doi: 10.5664/jcsm.9674.
Impact factor: 4.062
Publication type: Paper in international publication
Authors: Lloberes, Patricia, Ferrer, Jaume, Mota-Foix, Miriam, Sampol, Gabriel, Silveira, Maria Guadalupe et al.
DOI: 10.5664/jcsm.9674

Evidence for shared genetic risk factors between lymphangioleiomyomatosis and pulmonary function.

PMID: 35083324
Journal: ERJ open research
Year: 2022
Reference: ERJ Open Res. 2022 Jan 24;8(1). pii: 00375-2021. doi: 10.1183/23120541.00375-2021. eCollection 2022 Jan.
Impact factor: 0
Publication type: Paper in international publication
Authors: Valenzuela, Claudia, Ussetti, Piedad, Laporta, Rosalia, Rodriguez-Portal, Jose A, van Moorsel, Coline H M, van der Vis, Joanne J, Quanjel, Marian J R, Tena-Garitaonaindia, Mireia, Sanchez de Medina, Fermin, Mateo, Francesca et al.
DOI: 10.1183/23120541.00375-2021

Characterisation of Eosinophilic Bronchiectasis: A European Multicohort Study.

PMID: 35050830
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2022
Reference: Am J Respir Crit Care Med. 2022 Apr 15;205(8):894-902. doi: 10.1164/rccm.202108-1889OC.
Impact factor: 21.405
Publication type: Paper in international publication
Authors: Keir, Holly R, Loebinger, Michael R, Blasi, Francesco, Welte, Tobias, Sibila, Oriol, Aliberti, Stefano, Chalmers, James D, Altenburg, Josje, Polverino, Eva, Cant, Erin et al.
DOI: 10.1164/rccm.202108-1889OC

A new tool to screen patients with severe obstructive sleep apnea in the primary care setting: a prospective multicenter study.

PMID: 35033055
Journal: BMC Pulmonary Medicine
Year: 2022
Reference: BMC Pulm Med. 2022 Jan 15;22(1):38. doi: 10.1186/s12890-022-01827-0.
Impact factor: 3.317
Publication type: Paper in international publication
Authors: Farga Martinez, M feminine Del Mar, Reverte Simo, Montserrat, Argemi Saburit, Nuria, Medrano Medrano, Casimira, Puig Garcia, Marineus, Santos Santos, M feminineAngeles, Valverde Trillo, Pepi, Mayos, Merce, Penacoba, Patricia, Llauger, Maria Antonia et al.
DOI: 10.1186/s12890-022-01827-0

From Health-Related Quality of Life (HRQoL) of Patients with Pulmonary Hypertension to Patient Experience with the Care Received: Should We Be More Aware of Current Patient Needs?

PMID: 33675523
Journal: ADVANCES IN THERAPY
Year: 2021
Reference: Adv Ther. 2021 Apr;38(4):1860-1875. doi: 10.1007/s12325-021-01625-w. Epub 2021 Mar 6.
Impact factor: 3.847
Publication type: Paper in international publication
Authors: Martinez Menaca, Amaya, Blanco Vich, Isabel, Lopez Meseguer, Manuel, Lopez Reyes, Raquel, Bedate Diaz, Pedro, Elias Hernandez, Teresa, Fernandez-Cuesta Penafiel, Ines, Fernandez, Gonzalo, Alvez Liste, Ana, Escribano Subias, Pilar et al.
DOI: 10.1007/s12325-021-01625-w

Safety, diagnostic, and therapeutic value of flexible bronchoscopy in critically ill COVID-19 patients.

PMID: 33367993
Journal: Canadian Journal of Anesthesia-Journal canadien d anesthesie
Year: 2021
Reference: Can J Anaesth. 2021 Mar;68(3):434-435. doi: 10.1007/s12630-020-01887-y. Epub 2020 Dec 24.
Impact factor: 5.063
Publication type: Letter or abstract
Authors: Loor, Karina, Alvarez, Antonio, Felipe Montiel, Almudena, Ferrer, Ricard, Roca, Oriol, Garcia-de-Acilu, Marina, Clofent, David, Landivar, Jose Cardoso, Polverino, Eva, Culebras Amigo, Mario et al.
DOI: 10.1007/s12630-020-01887-y

What is important for people with nontuberculous mycobacterial disease? An EMBARC-ELF patient survey.

PMID: 33614773
Journal: ERJ open research
Year: 2021
Reference: ERJ Open Res. 2021 Feb 15;7(1). pii: 00807-2020. doi: 10.1183/23120541.00807-2020. eCollection 2021 Jan.
Impact factor: 0
Publication type: Letter whit IF
Authors: Posthumus, Annette, Ruddy, Thomas, Goeminne, Pieter, Lloyd, Ernie, Alan, Timothy, Altenburg, Josje, Crossley, Barbara, Blasi, Francesco, Chalmers, James, Berg, Tove et al.
DOI: 10.1183/23120541.00807-2020

Comorbidities and mortality risk factors for patients with bronchiectasis.

PMID: 33583300
Journal: Expert Review of Respiratory Medicine
Year: 2021
Reference: Expert Rev Respir Med. 2021 May;15(5):623-634. doi: 10.1080/17476348.2021.1886084. Epub 2021 Feb 17.
Impact factor: 3.772
Publication type: Paper in international publication
Authors: Clofent, David, Alvarez, Antonio, Traversi, Letizia, Culebras, Mario, Loor, Karina, Polverino, Eva et al.
DOI: 10.1080/17476348.2021.1886084

Phenotyping occupational asthma caused by acrylates in a multicentre cohort study.

PMID: 31678289
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2020
Reference: J Allergy Clin Immunol Pract. 2020 Mar;8(3):971-979.e1. doi: 10.1016/j.jaip.2019.10.017. Epub 2019 Oct 31.
Impact factor: 7.574
Publication type: Paper in international publication
Authors: Lindstrom, Irmeli, Sastre, Joaquin, Walusiak-Skorupa, Jolanta, Munoz, Xavier, Talini, Donatella, Klusackova, Pavlina, Moore, Vicky, Merget, Rolf, Svanes, Cecilie, Mason, Paola et al.
DOI: 10.1016/j.jaip.2019.10.017

Anti-HBc impacts on the risk of hepatitis B reactivation but not on survival of solid-organ transplant recipients.

PMID: 32118794
Journal: MEDICINE
Year: 2020
Reference: Medicine (Baltimore). 2020 Feb;99(9):e19407. doi: 10.1097/MD.0000000000019407.
Impact factor: 1.552
Publication type: Paper in international publication
Authors: Alvarez-Lopez, Patricia, Riveiro-Barciela, Mar, Oleas-Vega, Diana, Flores-Cortes, Claudia, Roman, Antonio, Perello, Manel, Berastegui, Cristina, Castells, Lluis, Esteban, Rafael, Buti, Maria et al.
DOI: 10.1097/MD.0000000000019407

Cell-Mediated Immune Responses to in vivo-Expressed and Stage-Specific Mycobacterium tuberculosis Antigens in Latent and Active Tuberculosis Across Different Age Groups.

PMID: 32117257
Journal: Frontiers in Immunology
Year: 2020
Reference: Front Immunol. 2020 Feb 11;11:103. doi: 10.3389/fimmu.2020.00103. eCollection 2020.
Impact factor: 5.085
Publication type: Paper in international publication
Authors: Franken, Kees L M C, Prat, Cristina, Stojanovic, Zoran, De Souza Galvao, Maria Luiza, Millet, Joan-Pau, Sabria, Josefina, Sanchez-Montalva, Adrian, Noguera-Julian, Antoni, Geluk, Annemieke, Dominguez, Jose et al.
DOI: 10.3389/fimmu.2020.00103

Echocardiographic Changes with Positive Airway Pressure Therapy in Obesity Hypoventilation Syndrome: Long-term Pickwick Randomized Controlled Trial.

PMID: 31682462
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2020
Reference: Am J Respir Crit Care Med. 2020 Mar 1;201(5):586-597. doi: 10.1164/rccm.201906-1122OC.
Impact factor: 17.452
Publication type: Paper in international publication
Authors: Barbe, Ferran, Corral, Jaime, Martel-Escobar, Maria, Negrin, Miguel A, Barca, Javier, Masa, Juan F, Mokhlesi, Babak, Benitez, Ivan, Mogollon, Maria Victoria, Gomez de Terreros, Francisco Javier et al.
DOI: 10.1164/rccm.201906-1122OC

The independent contribution of Pseudomonas aeruginosa infection to long-term clinical outcomes in bronchiectasis.

PMID: 29386336
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2018
Reference: Eur Respir J. 2018 Jan 31;51(2). pii: 51/2/1701953. doi: 10.1183/13993003.01953-2017. Print 2018 Feb.
Impact factor: 12.242
Publication type: Paper in international publication
Authors: Araujo, David, Shteinberg, Michal, Aliberti, Stefano, Goeminne, Pieter C, Hill, Adam T, Fardon, Thomas C, Obradovic, Dusanka, Stone, Glenda, Trautmann, Marion, Davis, Angela et al.
DOI: 10.1183/13993003.01953-2017

Asthma exacerbations: risk factors for hospital readmissions.

PMID: 28593573
Journal: IRISH JOURNAL OF MEDICAL SCIENCE
Year: 2018
Reference: Ir J Med Sci. 2018 Feb;187(1):155-161. doi: 10.1007/s11845-017-1633-9. Epub 2017 Jun 7.
Impact factor: 1.045
Publication type: Paper in international publication
Authors: Gonzalez-Barcala, F-J, Calvo-Alvarez, U, Garcia-Sanz, M-T, Garcia-Couceiro, N, Martin-Lancharro, P, Pose, A, Carreira, J-M, Moure-Gonzalez, J-D, Valdes-Cuadrado, L, Munoz, X et al.
DOI: 10.1007/s11845-017-1633-9

Correction: Lung and heart-lung transplantation in pulmonary arterial hypertension.

PMID: 29377947
Journal: PLoS One
Year: 2018
Reference: PLoS One. 2018 Jan 29;13(1):e0192100. doi: 10.1371/journal.pone.0192100. eCollection 2018.
Impact factor: 2.766
Publication type: Letter or abstract
Authors: Lopez-Meseguer, Manuel, Quezada, Carlos A, Ramon, Maria A, Lazaro, Maria, Dos, Laura, Lara, Antonio, Lopez, Raquel, Blanco, Isabel, Escribano, Pilar, Roman, Antonio et al.
DOI: 10.1371/journal.pone.0192100

RESPIRE 2: a phase III placebo-controlled randomised trial of ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis.

PMID: 29371384
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2018
Reference: Eur Respir J. 2018 Jan 25;51(1). pii: 51/1/1702053. doi: 10.1183/13993003.02053-2017. Print 2018 Jan.
Impact factor: 12.242
Publication type: Paper in international publication
Authors: Aksamit, Timothy, De Soyza, Anthony, Bandel, Tiemo-Joerg, Criollo, Margarita, Elborn, J Stuart, Operschall, Elisabeth, Polverino, Eva, Roth, Katrin, Winthrop, Kevin L, Wilson, Robert et al.
DOI: 10.1183/13993003.02053-2017

Restrictive Allograft Syndrome And Idiopathic Pleuroparenchymal Fibroelastosis: Do They Really Have The Same Histology?

PMID: 28120410
Journal: HISTOPATHOLOGY
Year: 2017
Reference: Histopathology. 2017 Jun;70(7):1107-1113. doi: 10.1111/his.13171. Epub 2017 Mar 20.
Impact factor: 3.523
Publication type: Paper in international publication
Authors: Montero, M Angeles, Osadolor, Tina, Khiroya, Reena, Salcedo, M Teresa, Robertus, Jan Lukas, Rice, Alexandra, Nicholson, Andrew G, Roman, Antonio, Monforte, Victor et al.
DOI: 10.1111/his.13171

Occupational lung diseases: from old and novel exposures to effective preventive strategies.

PMID: 28089118
Journal: Lancet Respiratory Medicine
Year: 2017
Reference: Lancet Respir Med. 2017 May;5(5):445-455. doi: 10.1016/S2213-2600(16)30424-6. Epub 2017 Jan 7.
Impact factor: 19.287
Publication type: Review in national publication
Authors: Cullinan, Paul, Munoz, Xavier, Suojalehto, Hille, Agius, Raymond, Jindal, Surinder, Sigsgaard, Torben, Blomberg, Anders, Charpin, Denis, Annesi-Maesano, Isabella, Gulati, Mridu et al.
DOI: 10.1016/S2213-2600(16)30424-6

Effect of adjunctive perampanel on the quality of sleep and daytime somnolence in patients with epilepsy.

PMID: 28066710
Journal: Epilepsy & behavior case reports
Year: 2017
Reference: Epilepsy Behav Case Rep. 2016 Oct 21;7:13-15. doi: 10.1016/j.ebcr.2016.10.002. eCollection 2017.
Impact factor: 0
Publication type: Paper in international publication
Authors: Salas-Puig, Xavier, Ferrer, Alex, Jurado, Maria Jose, Gonzalez-Cuevas, Montserrat, Romero, Odile, Toledo, Manuel, Quintana, Manuel, Cambrodi, Roser, Santamarina, Estevo et al.
DOI: 10.1016/j.ebcr.2016.10.002

Blog

News

This recognition highlights both his career and the level of respiratory research in Spain.

The ERS Awards recognize outstanding members for their exceptional contributions in the field of respiratory medicine.

Dr. Miravitlles’ career was recognized during the 57th edition of the SEPAR National Congress held in Valencia.

EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.