Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
The role of MNK kinases in cellular stress resistance.
The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Projects

Aislamiento y caracterización molecular de Células Tumorales Circulantes (CTCs): potenciales biomarcadores en Carcinoma Hepatocelular

IP: Beatriz Minguez Rosique
Collaborators: Itxarone Izaskun Bilbao Aguirre, Elena Vargas Accarino, Maria Teresa Salcedo Allende, Monica Higuera Urbano
Funding agency: Instituto de Salud Carlos III
Funding: 183920
Reference: PI21/00714
Duration: 01/01/2022 - 31/12/2025

Implementation and new biomarker development for Personalised Medicine for Childhood Cancers in Spain

IP: Lucas Moreno Martín-Retortillo
Collaborators: Aroa Soriano Fernández, Marta Garrido Pontnou, Miguel Segura Ginard, Lorena Valero Arrese, Raquel Hladun Alvaro, Elena Antima Martinez Saez, Marta Sese Faustino, Gabriela Guillén Burrieza, Josep Roma Castanyer, Andrea Vilaplana Blanes, Margarita Ortega Blanco, María Rosario Pérez- Torres Lobato, Asbleidy Carolina Torres Barbosa, Berta Campos Estela
Funding agency: Instituto de Salud Carlos III
Funding: 369260
Reference: PMP21/00073
Duration: 01/01/2022 - 31/12/2025

Publications

Hybrid neurofibroma/schwannoma of the orbit.

PMID: 37061243
Journal: Revista espanola de patologia
Year: 2023
Reference: Rev Esp Patol. 2023 Apr-Jun;56(2):140-143. doi: 10.1016/j.patol.2022.03.002. Epub 2022 Jun 15.
Impact factor:
Publication type: Letter or abstract
Authors: Arcediano, Miguel Angel; Arcediano, Miguel Angel; Dinares, Carme; Dinares, Carme; Naranjo, Lourdes; Ramon Y Cajal, Santiago; Ramon Y Cajal, Santiago; Romagosa, Cleofe; Romagosa, Cleofe; Salazar-Huayna, Lourdes et al.
DOI: 10.1016/j.patol.2022.03.002

Evaluation of triple negative breast cancer with heterogeneous immune infiltration.

PMID: 37215143
Journal: Frontiers in Immunology
Year: 2023
Reference: Front Immunol. 2023 May 4;14:1149747. doi: 10.3389/fimmu.2023.1149747. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Arenas, Enrique Javier; Arribas, Joaquin; Bernado, Cristina; Bernado, Cristina; Cortes, Javier; Curigliano, Giuseppe; Esteve-Codina, Anna; Gonzalez, Jonatan; Gonzalez, Jonatan; Marti, Merce et al.
DOI: 10.3389/fimmu.2023.1149747

Peripheral T-cell lymphoma with a T follicular-helper phenotype: A different entity? Results of the Spanish Real-T study.

PMID: 37386897
Journal: BRITISH JOURNAL OF HAEMATOLOGY
Year: 2023
Reference: Br J Haematol. 2023 Jun 30. doi: 10.1111/bjh.18941.
Impact factor:
Publication type: Paper in international publication
Authors: Baeza, Lourdes; Borrero, Juan Jose; Castellvi, Josep; Climent, Fina; Cordoba, Raul; Domingo-Domenech, Eva; Fraga, Maximo; Garcia-Cosio Piqueras, Monica; Gomez Codina, Jose; Gonzalez de Villambrosia, Sonia et al.
DOI: 10.1111/bjh.18941

Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis.

PMID: 37432984
Journal: CLINICAL CANCER RESEARCH
Year: 2023
Reference: Clin Cancer Res. 2023 Jul 11:CCR-22-2462. doi: 10.1158/1078-0432.CCR-22-2462.
Impact factor:
Publication type: Paper in international publication
Authors: Alaggio, Rita; Benassi, Maria Serena; Blanco-Aparicio, Carmen; Creus-Bachiller, Edgar; De Wever, Olivier; Di Giannatale, Angela; Fernandez-Rodriguez, Juana; Fischer, Suzanne; Garcia-Silva, Susana; Gonzalez-Munoz, Teresa et al.
DOI: 10.1158/1078-0432.CCR-22-2462

Exploratory study of an oral screening dysplasia program for HIV-infected men who have sex with men.

PMID: 35730367
Journal: AIDS
Year: 2022
Reference: AIDS. 2022 Aug 1;36(10):1383-1391. doi: 10.1097/QAD.0000000000003287. Epub 2022 Jun 22.
Impact factor:
Publication type: Paper in international publication
Authors: Burgos, Joaquin; Callejo, Angela; Curran, Adria; Dinares, Maria Carme; Falco, Vicenc; Garcia, Jorge; Hernandez-Losa, Javier; Molina, Maria Del Mar; Navarro, Jordi; Planas, Bibiana et al.
DOI: 10.1097/QAD.0000000000003287

Carotid web: the challenging diagnosis of an under-recognized entity.

PMID: 35713691
Journal: JOURNAL OF NEUROLOGY
Year: 2022
Reference: J Neurol. 2022 Oct;269(10):5629-5637. doi: 10.1007/s00415-022-11210-y. Epub 2022 Jun 17.
Impact factor:
Publication type: Paper in international publication
Authors: Arias-Rivas, Susana; Blanco Ulla, Miguel; Caicedo, Diego; Castineira, Jose Antonio; Fraga, Maximo; Lopez-Dequidt, Iria; Martinez-Saez, Elena; Mosqueira, Antonio Jesus; Mosquera, Nilo; Perez Beliz, Edurne et al.
DOI: 10.1007/s00415-022-11210-y

Gene expression profiles of beta-adrenergic receptors in canine vascular tumors: a preliminary study.

PMID: 35637463
Journal: BMC Veterinary Research
Year: 2022
Reference: BMC Vet Res. 2022 May 30;18(1):206. doi: 10.1186/s12917-022-03317-1.
Impact factor:
Publication type: Paper in international publication
Authors: Benitez-Fuste, Luis; Clanxet, Jordi; Hernandez-Losa, Javier; Pastor, Josep; Rueda, Manuel Ruiz-Echarri; Teles, Mariana et al.
DOI: 10.1186/s12917-022-03317-1

A Nine-Strain Bacterial Consortium Improves Portal Hypertension and Insulin Signaling and Delays NAFLD Progression In Vivo.

PMID: 35625927
Journal: Biomedicines
Year: 2022
Reference: Biomedicines. 2022 May 20;10(5). pii: biomedicines10051191. doi: 10.3390/biomedicines10051191.
Impact factor:
Publication type: Paper in international publication
Authors: Augustin, Salvador; Barbera, Aurora; Bolca, Selin; de Leeuw, Marcel; Estrella, Federico; Genesca, Joan; Gottardi, Davide; Horscroft, Nigel; Martell, Maria; Pinheiro, Iris et al.
DOI: 10.3390/biomedicines10051191

[Weakness as a complication of COVID-19 in critically ill patients: clinical features and prognostic factors in a case series].

PMID: 34170003
Journal: REVISTA DE NEUROLOGIA
Year: 2021
Reference: Rev Neurol. 2021 Jul 1;73(1):10-16. doi: 10.33588/rn.7301.2021042.
Impact factor:
Publication type: Paper in national publication
Authors: Ballve, A; Juntas-Morales, R; Lainez, E; Llaurado, A; Martinez-Saez, E; Palasi, A; Quintana, M; Raguer, N et al.
DOI: 10.33588/rn.7301.2021042

Acquired hepatocerebral degeneration in a metastatic neuroendocrine tumor long-term survivor - an update on neuroendocrine neoplasm's treatment: A case report.

PMID: 34131474
Journal: World journal of hepatology
Year: 2021
Reference: World J Hepatol. 2021 May 27;13(5):611-619. doi: 10.4254/wjh.v13.i5.611.
Impact factor:
Publication type: Letter or abstract
Authors: Auger, Cristina; Blanco, Laia; Capdevila, Jaume; Garcia-Burillo, Amparo; Gomez-Puerto, Diego; Landolfi, Stefania; Merino, Xavier; Mirallas, Oriol; Molero, Xavier; Riveiro-Barciela, Mar et al.
DOI: 10.4254/wjh.v13.i5.611

Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma.

PMID: 34150764
Journal: Frontiers in Cell and Developmental Biology
Year: 2021
Reference: Front Cell Dev Biol. 2021 Jun 3;9:670185. doi: 10.3389/fcell.2021.670185. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Davidson, Ben; de Alava, Enrique; de Andrea, Carlos; Diaz-Lagares, Angel; Diaz-Martin, Juan; Eritja, Nuria; Garcia Ros, David; Jacome, Maria Amalia; Lopez, Rafel; Matias-Guiu, Xavier et al.
DOI: 10.3389/fcell.2021.670185

The Novel KIF1A Missense Variant (R169T) Strongly Reduces Microtubule Stimulated ATPase Activity and Is Associated With NESCAV Syndrome.

PMID: 34121983
Journal: Frontiers in Neuroscience
Year: 2021
Reference: Front Neurosci. 2021 May 26;15:618098. doi: 10.3389/fnins.2021.618098. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera, Cinthia; Gabau, Elisabeth; Guitart, Miriam; Hummer, Stefan; Jeyaprakash, A Arockia; Masanas, Marc; Ruiz, Anna; Santamaria, Anna; Segura, Miguel F et al.
DOI: 10.3389/fnins.2021.618098

STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.

PMID: 32647375
Journal: Communications Biology
Year: 2020
Reference: Commun Biol. 2020 Jul 9;3(1):366. doi: 10.1038/s42003-020-1092-0.
Impact factor:
Publication type: Paper in international publication
Authors: Canals, Francesc; Espinosa-Gil, Sergio; Ferrer, Berta; Garcia-Ortega, Sara; Garcia-Patos, Vicenc; Gil, Rosa; Gonzalez-Sanchez, Elena; Granado-Martinez, Paula; Grueso, Judit; Hernandez-Losa, Javier et al.
DOI: 10.1038/s42003-020-1092-0

KIF11 and KIF15 mitotic kinesins are potential therapeutic vulnerabilities for malignant peripheral nerve sheath tumors.

PMID: 32642733
Journal: Neuro-oncology advances
Year: 2020
Reference: Neurooncol Adv. 2020 Jan 4;2(Suppl 1):i62-i74. doi: 10.1093/noajnl/vdz061. eCollection 2020 Jul.
Impact factor:
Publication type: Paper in international publication
Authors: Bernal, Gabriela; Biayna, Josep; Blanco, Ignacio; Fernandez, Marco; Fernandez-Rodriguez, Juana; Ferrer, Marc; Gel, Bernat; Guha, Rajiv; Lazaro, Conxi; Mazuelas, Helena et al.
DOI: 10.1093/noajnl/vdz061

Combining metabolic profiling of plasma and faeces as a fingerprint of insulin resistance in obesity.

PMID: 31708234
Journal: CLINICAL NUTRITION
Year: 2020
Reference: Clin Nutr. 2020 Jul;39(7):2292-2300. doi: 10.1016/j.clnu.2019.10.022. Epub 2019 Oct 25.
Impact factor:
Publication type: Paper in international publication
Authors: Caballano-Infantes, Estefania; Fernandez-Real, Jose-Manuel; Herance, Jose Raul; Mares, Roso; Mayneris-Perxachs, Jordi; Palomino-Schatzlein, Martina; Palomo-Buitrago, Maria-Encarnacion; Ricart, Wilfredo; Rodriguez, Maria Arnoriaga; Simo, Rafael et al.
DOI: 10.1016/j.clnu.2019.10.022

C4-C5 fused pyrazol-3-amines: when the degree of unsaturation and electronic characteristics of the fused ring controls regioselectivity in Ullmann and acylation reactions.

PMID: 32583833
Journal: ORGANIC & BIOMOLECULAR CHEMISTRY
Year: 2020
Reference: Org Biomol Chem. 2020 Jul 15;18(27):5145-5156. doi: 10.1039/d0ob00796j.
Impact factor:
Publication type: Paper in international publication
Authors: Borrell, Jose I; Bou-Petit, Elisabeth; Estrada-Tejedor, Roger; Font-Bardia, Merce; Plans, Arnau; Puigjaner, Cristina; Ramon Y Cajal, Santiago; Rodriguez-Picazo, Nieves; Teixido, Jordi; Torres-Coll, Antoni et al.
DOI: 10.1039/d0ob00796j

Trabectedin and RAdiotherapy in Soft Tissue Sarcoma (TRASTS): Results of a Phase I Study in Myxoid Liposarcoma from Spanish (GEIS), Italian (ISG), French (FSG) Sarcoma Groups.

PMID: 31143880
Journal: EClinicalMedicine
Year: 2019
Reference: EClinicalMedicine. 2019 Mar 11;9:35-43. doi: 10.1016/j.eclinm.2019.03.007. eCollection 2019 Mar.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Rosa; Blay, Jean-Yves; Casali, Paolo G; Cruz, Josefina; Dei Tos, Angelo P; Gronchi, Alessandro; Gutierrez, Antonio; Hindi, Nadia; Italiano, Antoine; Lopez-Pousa, Antonio et al.
DOI: 10.1016/j.eclinm.2019.03.007

Decompensated liver disease due to primary hepatic amyloidosis: Is liver transplantation still mandatory?

PMID: 30561765
Journal: HEPATOLOGY
Year: 2019
Reference: Hepatology. 2019 Jun;69(6):2701-2703. doi: 10.1002/hep.30464. Epub 2019 Mar 7.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Castells, Lluis; Esteban, Rafael; Gironella, Merche; Martinez-Valle, Fernando; Merino-Casabiel, Xavier; Riveiro-Barciela, Mar; Salcedo, Maria-Teresa; Senin, Alicia et al.
DOI: 10.1002/hep.30464

The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer.

PMID: 31141692
Journal: Cell Reports
Year: 2019
Reference: Cell Rep. 2019 May 28;27(9):2690-2708.e10. doi: 10.1016/j.celrep.2019.04.098.
Impact factor:
Publication type: Paper in international publication
Authors: Ali, H Raza; Arias, Alexandra; Bashford-Rogers, Rachael; Caldas, Carlos; Chin, Suet-Feung; Ciriaco, Nikaoly; Contente-Cuomo, Tania; Cope, Wei; Cortes, Javier; Dariush, Aliakbar et al.
DOI: 10.1016/j.celrep.2019.04.098

Sclerosing Cholangitis Related to IgG4: Not Always a Curable Entity.

PMID: 31113593
Journal: Annals of Hepatology
Year: 2019
Reference: Ann Hepatol. 2019 Jan - Feb;18(1):215-219. doi: 10.5604/01.3001.0012.7916.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Esteban, Rafael; Fernandez-Codina, Andreu; Martinez-Valle, Fernando; Merino-Casabiel, Xavier; Riveiro-Barciela, Mar; Salcedo, Maria-Teresa; Torres, Ines de et al.
DOI: 10.5604/01.3001.0012.7916

STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis.

PMID: 29892069
Journal: NATURE MEDICINE
Year: 2018
Reference: Nat Med. 2018 Jul;24(7):1024-1035. doi: 10.1038/s41591-018-0044-4. Epub 2018 Jun 11.
Impact factor:
Publication type: Paper in international publication
Authors: Bertero, Luca; Bindeman, Wendy; Blanco-Aparicio, Carmen; Bosch-Barrera, Joaquim; Cajal, Santiago Ramon Y; Doglio, Laura; Fustero-Torres, Coral; Hernandez-Encinas, Elena; Hernandez-Lain, Aurelio; Martinez, Liliana et al.
DOI: 10.1038/s41591-018-0044-4

Genetic Profiles of Squamous Cell Carcinomas Associated with Recessive Dystrophic Epidermolysis Bullosa Unveil NOTCH and TP53 Mutations and an Increased MYC Expression.

PMID: 29291383
Journal: JOURNAL OF INVESTIGATIVE DERMATOLOGY
Year: 2018
Reference: J Invest Dermatol. 2018 Jun;138(6):1423-1427. doi: 10.1016/j.jid.2017.12.026. Epub 2017 Dec 29.
Impact factor:
Publication type: Paper in international publication
Authors: Bodet, D; Caratu, G; Ferrer, B; Garcia-Patos, V; Gonzalez-Sanchez, E; Hernandez-Losa, J; Mancuso, F; McGrail, K; Perez-Alea, M; Recio, J A et al.
DOI: 10.1016/j.jid.2017.12.026

Analysis of intra-tumor heterogeneity in Neurofibromatosis Type 1 plexiform neurofibromas and neurofibromas with atypical features: Correlating histological and genomic findings.

PMID: 29774626
Journal: HUMAN MUTATION
Year: 2018
Reference: Hum Mutat. 2018 Aug;39(8):1112-1125. doi: 10.1002/humu.23552. Epub 2018 May 25.
Impact factor:
Publication type: Paper in international publication
Authors: Blanco, Ignacio; Carrio, Meritxell; Castellanos, Elisabeth; Gel, Bernat; Lazaro, Conxi; Lopez-Gutierrez, Juan Carlos; Moline, Teresa; Ramon Y Cajal, Santiago; Romagosa, Cleofe; Rosas, Inma et al.
DOI: 10.1002/humu.23552

Team Approach: Metastatic Disease of the Spine.

PMID: 29762343
Journal: JBJS reviews
Year: 2018
Reference: JBJS Rev. 2018 May;6(5):e6. doi: 10.2106/JBJS.RVW.17.00118.
Impact factor:
Publication type: Review in international publication
Authors: Benavente, Sergi; Casas-Gomila, Lourdes; Gonzalez-Tartiere, Pilar; Matamalas, Antonia; Pellise, Ferran; Romagosa, Cleofe; Valverde, Claudia et al.
DOI: 10.2106/JBJS.RVW.17.00118

ALDH1A3 is epigenetically regulated during melanocyte transformation and is a target for melanoma treatment.

PMID: 28581514
Journal: ONCOGENE
Year: 2017
Reference: Oncogene. 2017 Oct 12;36(41):5695-5708. doi: 10.1038/onc.2017.160. Epub 2017 Jun 5.
Impact factor:
Publication type: Paper in international publication
Authors: Ceylan, I; Cortes, J; Costello, R; Ferrer, B; Fournet, G; Garcia-Patos, V; Hernandez-Losa, J; Martin, G; McGrail, K; Munoz, E et al.
DOI: 10.1038/onc.2017.160

Angiolymphoid Hyperplasia with Eosinophilia Involving the Occipital Artery: Case Report and Review of Literature.

PMID: 28511526
Journal: Journal of clinical and diagnostic research : JCDR
Year: 2017
Reference: J Clin Diagn Res. 2017 Mar;11(3):ZD21-ZD23. doi: 10.7860/JCDR/2017/23323.9569. Epub 2017 Mar 1.
Impact factor:
Publication type: Review in international publication
Authors: Alberola-Ferranti, Margarita; Bescosatin, Coro; Fite-Trepat, Laia; Martos-Fernandez, Miriam; Pablo-Garcia-Cuenca, Alba De et al.
DOI: 10.7860/JCDR/2017/23323.9569

Spiny hyperkeratosis (trichodysplasia spinulosa-like eruption): a cutaneous adverse effect of Hedgehog pathway inhibitors involving expression of p16.

PMID: 27510735
Journal: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Year: 2017
Reference: J Eur Acad Dermatol Venereol. 2017 Apr;31(4):e182-e184. doi: 10.1111/jdv.13907. Epub 2016 Aug 30.
Impact factor:
Publication type: Paper in international publication
Authors: Ferrer, B; Garcia-Patos, V; Hernandez-Losa, J; Lopez-Lerma, I; Zarzoso, I et al.
DOI: 10.1111/jdv.13907

Target location after deep cerebral biopsies using low-volume air injection in 75 patients. Results and technical note.

PMID: 28470429
Journal: ACTA NEUROCHIRURGICA
Year: 2017
Reference: Acta Neurochir (Wien). 2017 Oct;159(10):1939-1946. doi: 10.1007/s00701-017-3191-3. Epub 2017 May 4.
Impact factor:
Publication type: Paper in international publication
Authors: Coscojuela, Pilar; Gandara, Dario F; Martinez-Ricarte, Francisco-Ramon; Martinez-Saez, Elena; Poca, Maria A; Sahuquillo, Juan et al.
DOI: 10.1007/s00701-017-3191-3

Different Prognostic Implications of Residual Disease After Neoadjuvant Treatment: Impact of Ki 67 and Site of Response.

PMID: 27357178
Journal: ANNALS OF SURGICAL ONCOLOGY
Year: 2016
Reference: Ann Surg Oncol. 2016 Nov;23(12):3831-3837. doi: 10.1245/s10434-016-5339-4. Epub 2016 Jun 29.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes, Javier; Diaz-Botero, Sebastian; Esgueva-Colmenarejo, Antonio; Espinosa-Bravo, Martin; Goncalves, Victor Rodrigues; Peg, Vicente; Perez, Jose; Rubio, Isabel T et al.
DOI: 10.1245/s10434-016-5339-4

Concordance study between one-step nucleic acid amplification and morphologic techniques to detect lymph node metastasis in papillary carcinoma of the thyroid.

PMID: 26614398
Journal: HUMAN PATHOLOGY
Year: 2016
Reference: Hum Pathol. 2016 Feb;48:132-41. doi: 10.1016/j.humpath.2015.09.020. Epub 2015 Oct 3.
Impact factor:
Publication type: Paper in international publication
Authors: Baena, Jose Antonio; Cuevas, Dolors; de Alava, Enrique; Del Carmen, Sofia; Franch-Arcas, Guzman; Gatius, Sonia; Gonzalez, Oscar; Iglesias, Carmela; Macias, Carmen Garcia; Martinez, Mercedes et al.
DOI: 10.1016/j.humpath.2015.09.020

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway.

PMID: 27057633
Journal: Oncotarget
Year: 2016
Reference: Oncotarget. 2016 May 10;7(19):28086-95. doi: 10.18632/oncotarget.8578.
Impact factor:
Publication type: Paper in international publication
Authors: Caratu, Ginevra; Cortes, Javier; Ferrer, Berta; Garcia-Patos, Vicente; Hernandez-Losa, Javier; Matito, Judit; Munoz, Eva; Perez-Alea, Mileidys; Recio, Juan A; Vivancos, Ana et al.
DOI: 10.18632/oncotarget.8578

Myositis ossificans of the masseter muscle: A rare location. Report of a case and review of literature.

PMID: 27034763
Journal: Journal of clinical and experimental dentistry
Year: 2016
Reference: J Clin Exp Dent. 2016 Apr 1;8(2):e210-3. doi: 10.4317/jced.52888. eCollection 2016 Apr.
Impact factor:
Publication type: Paper in international publication
Authors: Alberola-Ferranti, Margarita; Bescos-Atin, Coro; Fite-Trepat, Laia; Martos-Fernandez, Miriam; Romanini-Montecino, Carolina; Saez-Barba, Manel et al.
DOI: 10.4317/jced.52888

Tenofovir discontinuation after long-term viral suppression in HBeAg negative chronic hepatitis B. Can HBsAg levels be useful?

PMID: 26071338
Journal: J CLIN VIROL
Year: 2015
Reference: J Clin Virol. 2015 Jul;68:61-8. doi: 10.1016/j.jcv.2015.05.002. Epub 2015 May 8.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Casillas, Rosario; Esteban, Rafael; Homs, Maria; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Salcedo, Maria Teresa; Tabernero, David et al.
DOI: 10.1016/j.jcv.2015.05.002

A cluster of protein kinases and phosphatases modulated in fetal Down syndrome (trisomy 21) brain.

PMID: 25740605
Journal: AMINO ACIDS
Year: 2015
Reference: Amino Acids. 2015 Jun;47(6):1127-34. doi: 10.1007/s00726-015-1941-1. Epub 2015 Mar 5.
Impact factor:
Publication type: Paper in international publication
Authors: Dierssen, Mara; Lubec, Gert; Pollak, Arnold; Subramaniyan, Saraswathi; Toran, Nuria; Weitzdoerfer, Rachel et al.
DOI: 10.1007/s00726-015-1941-1

Expression of YY1 in Differentiated Thyroid Cancer.

PMID: 25698133
Journal: ENDOCR PATHOL
Year: 2015
Reference: Endocr Pathol. 2015 May;26(2):111-8. doi: 10.1007/s12022-015-9359-6.
Impact factor:
Publication type: Paper in international publication
Authors: Arribas, Jessica; Castellvi, Josep; Marcos, Ricard; Velazquez, Antonia; Zafon, Carles et al.
DOI: 10.1007/s12022-015-9359-6

DNA methylation abnormalities in congenital heart disease.

PMID: 25587870
Journal: EPIGENETICS-US
Year: 2015
Reference: Epigenetics. 2015;10(2):167-77. doi: 10.1080/15592294.2014.998536.
Impact factor:
Publication type: Paper in international publication
Authors: Cusco, Ivon; Flores, Raquel; Homs, Aida; Perez-Jurado, Luis A; Serra-Juhe, Clara; Toran, Nuria et al.
DOI: 10.1080/15592294.2014.998536

Capturing Intra-Tumor Genetic Heterogeneity by De Novo Mutation Profiling of Circulating Cell-Free Tumor DNA: A Proof-of-Principle.

PMID: 25009010
Journal: ANNALS OF ONCOLOGY
Year: 2014
Reference: Ann Oncol. 2014 Sep;25(9):1729-35. doi: 10.1093/annonc/mdu239. Epub 2014 Jul 9.
Impact factor:
Publication type: Paper in international publication
Authors: Aura, C; Berger, M F; Bidard, F-C; Cortes, J; De Mattos-Arruda, L; Ng, C K Y; Norton, L; Nuciforo, P; Oliveira, M; Patel, P et al.
DOI: 10.1093/annonc/mdu239

Langerhans cell histiocytosis associated with papillary thyroid carcinoma.

PMID: 24361211
Journal: REVISTA CLINICA ESPANOLA
Year: 2014
Reference: Rev Clin Esp. 2014 Mar;214(2):e19-21. doi: 10.1016/j.rce.2013.11.005. Epub 2013 Dec 20.
Impact factor:
Publication type: Paper in national publication
Authors: Biagetti, B; Diego, E; Gonzalez, O; Iglesias, C; Mesa, J et al.
DOI: 10.1016/j.rce.2013.11.005

Angiolymphoid hyperplasia with eosinophilia of the eyelid and orbit: the Western cousin of Kimura's disease?

PMID: 23460400
Journal: International ophthalmology
Year: 2014
Reference: Int Ophthalmol. 2014 Feb;34(1):107-10. doi: 10.1007/s10792-013-9741-7. Epub 2013 Mar 5.
Impact factor:
Publication type: Letter or abstract
Authors: Alonso, T; Cunniffe, G; Dinares, C; Medel, R; Medina, F J et al.
DOI: 10.1007/s10792-013-9741-7

RPLP1, a Crucial Ribosomal Protein for Embryonic Development of the Nervous System.

PMID: 24959908
Journal: PLoS One
Year: 2014
Reference: PLoS One. 2014 Jun 24;9(6):e99956. doi: 10.1371/journal.pone.0099956. eCollection 2014.
Impact factor:
Publication type: Paper in international publication
Authors: Artero-Castro, Ana; Guerrero, Sergi; LLeonart, Matilde E; Perucho, Laura; Ramon Y Cajal, Santiago; Wang, Zhao-Qi et al.
DOI: 10.1371/journal.pone.0099956

Determining the profiles and parameters for gene amplification testing of growth factor receptors in lung cancer.

PMID: 23400671
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2013
Reference: Int J Cancer. 2013 Aug 15;133(4):898-907. doi: 10.1002/ijc.28090. Epub 2013 Mar 9.
Impact factor:
Publication type: Paper in international publication
Authors: Bonastre, Ester; Brambilla, Elisabeth; Cajal, Santiago Ramon Y; Castellvi, Josep; Castillo, Sandra D; Cigudosa, Juan C; Conde, Esther; Lantuejoul, Sylvie; Lopez-Rios, Fernando; Pros, Eva et al.
DOI: 10.1002/ijc.28090

Identification of the novel mutation m.5658T>C in the mitochondrial tRNA(Asn) gene in a patient with myopathy, bilateral ptosis and ophthalmoparesis.

PMID: 23375258
Journal: NEUROMUSCULAR DISORDERS
Year: 2013
Reference: Neuromuscul Disord. 2013 Apr;23(4):330-6. doi: 10.1016/j.nmd.2013.01.001. Epub 2013 Jan 31.
Impact factor:
Publication type: Paper in international publication
Authors: Andreu, Antoni L; Camara, Yolanda; Gallardo, Eduard; Garcia-Arumi, Elena; Hernandez-Losa, Javier; Martinez-Vea, Albert; Melia, Maria Jesus; Ortiz, Nicolau; Pinos, Tomas; Raventos-Estelle, Antoni et al.
DOI: 10.1016/j.nmd.2013.01.001

Fluorescence in situ hybridization and immunohistochemistry as diagnostic methods for ALK positive non-small cell lung cancer patients.

PMID: 23359795
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013;8(1):e52261. doi: 10.1371/journal.pone.0052261. Epub 2013 Jan 24.
Impact factor:
Publication type: Paper in international publication
Authors: Canela, Mercedes; Castellvi, Josep; Cedres, Susana; Felip, Enriqueta; Hernandez-Losa, Javier; Martinez, Pablo; Martinez-Marti, Alex; Montero, Ma Angeles; Murtra-Garrell, Nuria; Navarro-Mendivill, Alejandro et al.
DOI: 10.1371/journal.pone.0052261

Epithelial-mesenchymal transition markers and HER3 expression are predictors of elisidepsin treatment response in breast and pancreatic cancer cell lines.

PMID: 23320098
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013;8(1):e53645. doi: 10.1371/journal.pone.0053645. Epub 2013 Jan 8.
Impact factor:
Publication type: Paper in international publication
Authors: Aracil, Miguel; Hernandez-Losa, Javier; Mares, Roso; Ramon y Cajal, Santiago; Teixido, Cristina et al.
DOI: 10.1371/journal.pone.0053645

Risk factors for progression or persistence of squamous intraepithelial lesions diagnosed during pregnancy.

PMID: 22126830
Journal: Journal of Lower Genital Tract Disease
Year: 2012
Reference: J Low Genit Tract Dis. 2012 Jan;16(1):34-8.
Impact factor:
Publication type: Paper in international publication
Authors: Castellvi, Josep; Centeno-Mediavilla, Cristina; Cubo-Abert, Montserrat; Franco-Zabala, Patricia; Garcia, Angel; Gil-Moreno, Antonio; Merced-Vazquez, Carmen; Xercavins, Jordi et al.
DOI: 10.1097/LGT.0b013e31822e83cf

ErbB3 expression predicts sensitivity to elisidepsin treatment: in vitro synergism with cisplatin, paclitaxel and gemcitabine in lung, breast and colon cancer cell lines.

PMID: 22485250
Journal: INTERNATIONAL JOURNAL OF ONCOLOGY
Year: 2012
Reference: Int J Oncol. 2012 Jul;41(1):317-24. doi: 10.3892/ijo.2012.1425. Epub 2012 Apr 3.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.3892/ijo.2012.1425

Molecular prescreening to select patient population in early clinical trials.

PMID: 22473105
Journal: Nature Reviews Clinical Oncology
Year: 2012
Reference: Nat Rev Clin Oncol. 2012 Apr 3;9(6):359-66. doi: 10.1038/nrclinonc.2012.48.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1038/nrclinonc.2012.48

Differential expression of Kv1.3 and Kv1.5 voltage-dependent K+ channels in human skeletal muscle sarcomas.

PMID: 22360360
Journal: CANCER INVESTIGATION
Year: 2012
Reference: Cancer Invest. 2012 Mar;30(3):203-8.
Impact factor:
Publication type: Paper in international publication
Authors: Bielanska, Joanna; Condom, Enric; Felipe, Antonio; Ferreres, Joan Carles; Hernandez-Losa, Javier; Moline, Teresa; Ramon y Cajal, Santiago; Somoza, Rosa et al.
DOI: 10.3109/07357907.2012.654872

Balance between MKK6 and MKK3 mediates p38 MAPK associated resistance to cisplatin in NSCLC.

PMID: 22164285
Journal: PLoS One
Year: 2011
Reference: PLoS One. 2011;6(12):e28406. doi: 10.1371/journal.pone.0028406. Epub 2011 Dec 2.
Impact factor: 4.411
Publication type: Paper in international publication
Authors: Galan-Moya, Eva M, Llanos Valero, Maria, Callejas-Valera, Juan L, Melgar-Rojas, Pedro, Hernadez Losa, Javier, Salcedo, Mayte, Fernandez-Aramburo, Antonio, Ramon y Cajal, Santiago, Sanchez-Prieto, Ricardo, de la Cruz-Morcillo, Miguel A et al.
DOI: 10.1371/journal.pone.0028406

Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma.

PMID: 22131884
Journal: NEOPLASIA
Year: 2011
Reference: Neoplasia. 2011 Nov;13(11):1093-100.
Impact factor: 5.476
Publication type: Paper in international publication
Authors: Buggy, Joseph J, Kortlever, Roderik, Adimoolam, Shanthi, Monclus, Helena Allende, Allende, Maria Teresa Salcedo, Swigart, Lamorna Brown, Evan, Gerard I, Soucek, Laura et al.
DOI:

Down-regulation of spinophilin in lung tumours contributes to tumourigenesis.

PMID: 21598252
Journal: JOURNAL OF PATHOLOGY
Year: 2011
Reference: J Pathol. 2011 Sep;225(1):73-82. doi: 10.1002/path.2905. Epub 2011 May 19.
Impact factor: 7.274
Publication type: Paper in international publication
Authors: Molina-Pinelo, Sonia, Ferrer, Irene, Blanco-Aparicio, Carmen, Peregrino, Sandra, Pastor, Maria Dolores, Alvarez-Vega, Juan, Suarez, Rocio, Verge, Mar, Marin, Juan J, Hernandez-Losa, Javier et al.
DOI: 10.1002/path.2905

KAP Degradation by Calpain Is Associated with CK2 Phosphorylation and Provides a Novel Mechanism for Cyclosporine A-Induced Proximal Tubule Injury.

PMID: 21980535
Journal: PLoS One
Year: 2011
Reference: PLoS One. 2011;6(9):e25746. Epub 2011 Sep 28.
Impact factor: 4.411
Publication type: Paper in international publication
Authors: Tornavaca, Olga, Sarro, Eduard, Pascual, Gloria, Bardaji, Beatriz, Montero, M Angeles, Salcedo, M Teresa, Plana, Maria, Lopez-Hellin, Joan, Itarte, Emilio, Meseguer, Anna et al.
DOI: 10.1371/journal.pone.0025746

[Giant cell tumor of bone in a patient with HIV infection.]

PMID: 20096969
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2010
Reference: Enferm Infecc Microbiol Clin. 2010 Jun-Jul;28(6):396-7. Epub 2010 Jan 22.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; ; ; et al.
DOI: 10.1016/j.eimc.2009.09.003

Turning human epidermis into pancreatic endoderm.

PMID: 21060974
Journal:
Year: 2010
Reference: Rev Diabet Stud. 2010 Summer;7(2):158-67. doi: 10.1900/RDS.2010.7.158. Epub 2010 Aug 10.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Clemente-Casares, Xavier; Izpisua Belmonte, Juan Carlos; Mulero-Perez, Lola; Raya, Angel; Rodriguez-Piza, Ignacio; Santamaria, Pere; Yamanouchi, Jun et al.
DOI: 10.1900/RDS.2010.7.158

Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells.

PMID: 20134422
Journal:
Year: 2010
Reference: Nat Protoc. 2010 Feb;5(2):371-82. doi: 10.1038/nprot.2009.241. Epub 2010 Feb 4.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Izpisua Belmonte, Juan Carlos et al.
DOI: 10.1038/nprot.2009.241

Differences in the Form of Presentation between Papillary Microcarcinomas and Papillary Carcinomas of Larger Size.

PMID: 21209704
Journal: Journal of thyroid research
Year: 2010
Reference: J Thyroid Res. 2010 Dec 14;2011:639156.
Impact factor:
Publication type: Letter or abstract
Authors: Zafon, Carles, Baena, Juan Antonio, Castellvi, Josep, Obiols, Gabriel, Monroy, Gabriela, Mesa, Jordi et al.
DOI: 10.4061/2011/639156

[Powdered infant formulae preparation guide for hospitals based on Hazard Analysis and Critical Control Points (HACCP) principles]

PMID: 19427820
Journal: ANALES DE PEDIATRIA
Year: 2009
Reference: An Pediatr (Barc). 2009 Jun;70(6):586-93.
Impact factor:
Publication type: Letter or abstract
Authors: Campins Marti, M; Lorite Cuenca, R; Perez-Portabella, C; Redecillas Ferreiro, S; Rodriguez Garrido, V; Vargas-Leguas, H et al.
DOI: 10.1016/j.anpedi.2009.01.006

Cell signaling in endometrial carcinoma: phosphorylated 4E-binding protein-1 expression in endometrial cancer correlates with aggressive tumors and prognosis.

PMID: 19428047
Journal: HUMAN PATHOLOGY
Year: 2009
Reference: Hum Pathol. 2009 Oct;40(10):1418-26.
Impact factor:
Publication type: Paper in international publication
Authors: Castellvi, Josep; Garcia, Angel; Gil-Moreno, Antonio; Hernandez-Losa, Javier; Peg, Vicente; Ramon y Cajal, Santiago; Ruiz-Marcellan, Carmen; Salcedo, Mayte et al.
DOI: 10.1016/j.humpath.2008.12.019

[Schistosomiasis as a cause of acute appendicitis]

PMID: 19406390
Journal: Cir Esp
Year: 2009
Reference: Cir Esp. 2009 Jun;85(6):387-9.
Impact factor:
Publication type: Letter or abstract
Authors: Armengol Carrasco, Manuel; Landolfi, Stefania; Lopez de Cenarruzabeitia, Inigo; Rodriguez Conde, Nivardo; Senuque Artini, Marcela et al.
DOI: 10.1016/j.ciresp.2008.05.002

Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors.

PMID: 19584160
Journal: CLINICAL CANCER RESEARCH
Year: 2009
Reference: Clin Cancer Res. 2009 Jul 15;15(14):4546-53.
Impact factor:
Publication type: Paper in international publication
Authors: Argelaguet, Elisabet; Armengol, Gemma; Coch, Laura; de Torres, Ines; Hernandez-Losa, Javier; Lleonart, Matilde; Lopez-Vicente, Laura; Pons, Berta; Ramon y Cajal, Santiago et al.
DOI: 10.1158/1078-0432.CCR-08-3159

Blog

News

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

Current Rates

PDF 0.25 MB

Download

Rates Anatomia Patologica VHIR 2021

PDF 0.22 MB