Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
The role of MNK kinases in cellular stress resistance.
The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Projects

Aquest any no hi ha projectes actius.

Publications

A PET-CT score for discriminating malignant from benign pleural effusions.

PMID: 37487808
Journal: MEDICINA CLINICA
Year: 2023
Reference: Med Clin (Barc). 2023 Jul 22:S0025-7753(23)00368-8. doi: 10.1016/j.medcli.2023.06.011.
Impact factor:
Publication type: Paper in national publication
Authors: Aleman, Carmen; Montoro, Bruno; Persiva, Oscar; Sanchez, Leire; Sanchez, Leire; Sansano, Irene; Simo, Marc; Vazquez, Ana et al.
DOI: 10.1016/j.medcli.2023.06.011

Xpert Bladder Cancer Monitor for the Early Detection of Non-Muscle Invasive Bladder Cancer Recurrences: Could Cystoscopy Be Substituted?

PMID: 37509344
Journal: Cancers
Year: 2023
Reference: Cancers (Basel). 2023 Jul 19;15(14):3683. doi: 10.3390/cancers15143683.
Impact factor:
Publication type: Paper in international publication
Authors: Carrion, Albert; Dinares, Carme; Hernandez, Javier; Hernandez, Javier; Lozano, Fernando; Morote, Juan; Raventos, Carles X; Trilla, Enrique et al.
DOI: 10.3390/cancers15143683

OSNA Total Tumor Load for the Prediction of Axillary Involvement in Breast Cancer Patients: Should We use Different Thresholds According to the Intrinsic Molecular Subtype? MOTTO Study.

PMID: 37534372
Journal: Clinical Pathology
Year: 2023
Reference: Clin Pathol. 2023 Jul 31;16:2632010X231183693. doi: 10.1177/2632010X231183693. eCollection 2023 Jan-Dec.
Impact factor:
Publication type: Paper in international publication
Authors: Bernet, L; Cordoba, A; Godey, F; Hardisson, D; Peg, V; Prat, A; Rodrigo, M; Ruiz, I; Sanchez-Mendez, J I; Sancho, M et al.
DOI: 10.1177/2632010X231183693

Matrix Metalloproteinase-9 Expression Is Associated with the Absence of Response to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer Patients.

PMID: 37511057
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2023
Reference: Int J Mol Sci. 2023 Jul 11;24(14):11297. doi: 10.3390/ijms241411297.
Impact factor:
Publication type: Paper in international publication
Authors: Alvaro, Tomas; Arenas, Meritxell; Bosch, Ramon; de la Cruz-Merino, Luis; Galera, Juana; Gallardo, Noelia; Garcia-Fontgivell, Joan; Korzynska, Anna; Lejeune, Marylene; Lopez, Carlos et al.
DOI: 10.3390/ijms241411297

Cx43-mediated sorting of miRNAs into extracellular vesicles.

PMID: 35593040
Journal: EMBO REPORTS
Year: 2022
Reference: EMBO Rep. 2022 Jul 5;23(7):e54312. doi: 10.15252/embr.202154312. Epub 2022 May 20.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Catarino, Steve; Costa, Marina C; Enguita, Francisco J; Girao, Henrique; Martins-Marques, Tania; Simoes, Isaura et al.
DOI: 10.15252/embr.202154312

Non-Invasive Tests of Liver Fibrosis Help in Predicting the Development of Hepatocellular Carcinoma among Patients with NAFLD.

PMID: 35566592
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Apr 27;11(9). pii: jcm11092466. doi: 10.3390/jcm11092466.
Impact factor:
Publication type: Paper in international publication
Authors: Augustin, Salvador; Banares, Juan; Bermudez, Maria; Castells, Lluis; Manzano, Ramiro; Minguez, Beatriz; Pericas, Juan M; Pons, Monica; Rivera-Esteban, Jesus; Salcedo-Allende, Maria Teresa et al.
DOI: 10.3390/jcm11092466

A high-throughput screening platform identifies novel combination treatments for Malignant Peripheral Nerve Sheath Tumors.

PMID: 35511749
Journal: MOLECULAR CANCER THERAPEUTICS
Year: 2022
Reference: Mol Cancer Ther. 2022 Jul 5;21(7):1246-1258. doi: 10.1158/1535-7163.MCT-21-0947.
Impact factor:
Publication type: Paper in international publication
Authors: Blakeley, Jaishri O; Creus-Bachiller, Edgar; Fernandez-Rodriguez, Juana; Ferrer, Marc; Guha, Rajarshi; Lazaro, Conxi; Martinez-Iniesta, Maria; Ortega-Bertran, Sara; Pujana, Miguel Angel; Reilly, Karlyne M et al.
DOI: 10.1158/1535-7163.MCT-21-0947

High levels of chromosomal aberrations negatively associate with benefit to checkpoint inhibition in NSCLC.

PMID: 35477861
Journal: Journal for ImmunoTherapy of Cancer
Year: 2022
Reference: J Immunother Cancer. 2022 Apr;10(4). pii: jitc-2021-004197. doi: 10.1136/jitc-2021-004197.
Impact factor:
Publication type: Paper in international publication
Authors: Amat, Ramon; Callejo, Ana; Carbonell, Caterina; Cedres, Susana; Felip, Enriqueta; Frigola, Joan; Hernandez-Losa, Javier; Irazno, Patricia; Jimenez, Jose; Martinez-Marti, Alex et al.
DOI: 10.1136/jitc-2021-004197

COVID-19 in CKD Patients: Lessons from 553 CKD Patients with Biopsy-Proven Kidney Disease.

PMID: 34098555
Journal: KIDNEY & BLOOD PRESSURE RESEARCH
Year: 2021
Reference: Kidney Blood Press Res. 2021;46(4):452-459. doi: 10.1159/000515714. Epub 2021 Jun 7.
Impact factor:
Publication type: Paper in international publication
Authors: Agraz, Irene; Baldallo, Cinthia; Bury, Roxana; Gabaldon, Alejandra; Garcia-Carro, Clara; Roman, Juan Leon; Seron, Daniel; Soler, Maria Jose; Toapanta, Nestor; Torres, Irina et al.
DOI: 10.1159/000515714

Spontaneous Cell Detachment and Reattachment in Cancer Cell Lines: An In Vitro Model of Metastasis and Malignancy.

PMID: 34066490
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 May 6;22(9). pii: ijms22094929. doi: 10.3390/ijms22094929.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Herrera-Montavez, Carlos; Ramon Y Cajal, Santiago; Vargas-Accarino, Elena et al.
DOI: 10.3390/ijms22094929

A Specific Tubular ApoA-I Distribution Is Associated to FSGS Recurrence after Kidney Transplantation.

PMID: 34069888
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 May 18;10(10). pii: jcm10102174. doi: 10.3390/jcm10102174.
Impact factor:
Publication type: Paper in international publication
Authors: Agraz, Irene; Gabaldon, Maria-Alejandra; Jacobs-Cacha, Conxita; Lopez-Hellin, Joan; Moreso, Francesc; Puig-Gay, Natalia; Sellares, Joana; Seron, Daniel; Soler, Maria Jose; Vergara, Ander et al.
DOI: 10.3390/jcm10102174

Reliability of histopathologic diagnosis of fibrotic interstitial lung disease: an international collaborative standardization project.

PMID: 34074264
Journal: BMC Pulmonary Medicine
Year: 2021
Reference: BMC Pulm Med. 2021 Jun 1;21(1):184. doi: 10.1186/s12890-021-01522-6.
Impact factor:
Publication type: Paper in international publication
Authors: Attanoos, Richard; Camp, Robert; Fabro, Alexandre Todorovic; Farver, Carol; Homer, Robert J; Larsen, Brandon T; Moreira, Andre L; Pillappa, Raghavendra; Roden, Anja C; Sansano, Irene et al.
DOI: 10.1186/s12890-021-01522-6

Fusobacterium nucleatum persistence and risk of recurrence after preoperative treatment in locally advanced rectal cancer.

PMID: 32569727
Journal: ANNALS OF ONCOLOGY
Year: 2020
Reference: Ann Oncol. 2020 Oct;31(10):1366-1375. doi: 10.1016/j.annonc.2020.06.003. Epub 2020 Jun 20.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, L; Bullman, S; Capdevila, J; Comas, R; Dienstmann, R; Elez, E; Fasani, R; Hernando, J; Jimenez, J; Landolfi, S et al.
DOI: 10.1016/j.annonc.2020.06.003

Intraoperative Human Papillomavirus Test Predicts 24-Month High-Grade Squamous Intraepithelial Lesion Recurrence Saving Costs: A Prospective Cohort Study.

PMID: 32569022
Journal: Journal of Lower Genital Tract Disease
Year: 2020
Reference: J Low Genit Tract Dis. 2020 Oct;24(4):367-371. doi: 10.1097/LGT.0000000000000549.
Impact factor:
Publication type: Paper in international publication
Authors: Alcalde, Ana; Bradbury, Melissa; Cabrera, Silvia; Centeno, Cristina; Forcada, Cristina; Garcia, Angel; Gil-Moreno, Antonio; Guerrero, Diana; Hernandez, Javier; Perez-Benavente, Assumpcio et al.
DOI: 10.1097/LGT.0000000000000549

Modelling the skeletal muscle injury recovery using in vivo contrast-enhanced micro-CT: a proof-of-concept study in a rat model.

PMID: 32488324
Journal: European radiology experimental
Year: 2020
Reference: Eur Radiol Exp. 2020 Jun 3;4(1):33. doi: 10.1186/s41747-020-00163-4.
Impact factor:
Publication type: Paper in international publication
Authors: Baleriola, Mario Marotta; Cabello, Alex Claveria; Camacho, Jose Raul Herance; Castell-Conesa, Joan; de la Calle Vargas, Elena; Garcia, Vanessa Venegas; Leon, Daniel Garcia; Munoz, Paola Contreras; Pages, Roso Mares; Paun, Bruno et al.
DOI: 10.1186/s41747-020-00163-4

A Translational In Vivo and In Vitro Metabolomic Study Reveals Altered Metabolic Pathways in Red Blood Cells of Type 2 Diabetes.

PMID: 32471219
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 May 27;9(6). pii: jcm9061619. doi: 10.3390/jcm9061619.
Impact factor:
Publication type: Paper in international publication
Authors: Aparicio-Gomez, Carolina; Ciudin, Andreea; Gutierrez-Carcedo, Patricia; Herance, Jose Raul; Hernandez, Cristina; Lamas-Domingo, Ruben; Mares, Roso; Palomino-Schatzlein, Martina; Simo, Rafael et al.
DOI: 10.3390/jcm9061619

Dendritic Cells From the Cervical Mucosa Capture and Transfer HIV-1 via Siglec-1.

PMID: 31114569
Journal: Frontiers in Immunology
Year: 2019
Reference: Front Immunol. 2019 Apr 30;10:825. doi: 10.3389/fimmu.2019.00825. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Arnau-Saz, Vicent; Benet, Susana; Buzon, Maria J; Cantero-Perez, Jon; Castellvi, Josep; Erkizia, Itziar; Garrido, Julio; Genesca, Meritxell; Hernandez-Gallego, Alba; Izquierdo-Useros, Nuria et al.
DOI: 10.3389/fimmu.2019.00825

Clinicopathological and Molecular Characterization of Metastatic Gastrointestinal Stromal Tumors with Prolonged Benefit to Frontline Imatinib.

PMID: 30126859
Journal: ONCOLOGIST
Year: 2019
Reference: Oncologist. 2019 May;24(5):680-687. doi: 10.1634/theoncologist.2018-0032. Epub 2018 Aug 20.
Impact factor:
Publication type: Paper in international publication
Authors: Arribas, Joaquin; Carles, Joan; Diaz-Beveridge, Roberto; Duran, Jose; Estival, Anna; Garcia-Del-Muro, Xavier; Hernandez-Losa, Javier; Hindi, Nadia; Jimenez, Laura; Landolfi, Stefania et al.
DOI: 10.1634/theoncologist.2018-0032

Autophagy inhibition as a promising therapeutic target for laryngeal cancer.

PMID: 31050705
Journal: CARCINOGENESIS
Year: 2019
Reference: Carcinogenesis. 2019 Dec 31;40(12):1525-1534. doi: 10.1093/carcin/bgz080.
Impact factor:
Publication type: Paper in international publication
Authors: Benavente, Sergi; Castellvi, Josep; Garcia-Mayea, Yoelsis; LLeonart, Matilde E; Lorente, Juan; Maggio, Valentina; Mir, Cristina; Munoz, Lisandra; Paciucci, Rosanna; Temprana, Jordi et al.
DOI: 10.1093/carcin/bgz080

Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages.

PMID: 31028084
Journal: EMBO JOURNAL
Year: 2019
Reference: EMBO J. 2019 Jun 3;38(11). pii: embj.2018100299. doi: 10.15252/embj.2018100299. Epub 2019 Apr 26.
Impact factor:
Publication type: Paper in international publication
Authors: Castellvi, Josep; Dill, Brian D; Emmerich, Christoph H; Gierlinski, Marek; Guo, Manman; Hartlova, Anetta; Losa, Javier Hernandez; Petersen, Sine K; Prescott, Alan; Ramon Y Cajal, Santiago et al.
DOI: 10.15252/embj.2018100299

Genetic heterogeneity and actionable mutations in HER2-positive primary breast cancers and their brain metastases.

PMID: 29755676
Journal: Oncotarget
Year: 2018
Reference: Oncotarget. 2018 Apr 17;9(29):20617-20630. doi: 10.18632/oncotarget.25041. eCollection 2018 Apr 17.
Impact factor:
Publication type: Paper in international publication
Authors: Arias, Alexandra; Casas, Francesc Tresserra; Cortes, Javier; De Filippo, Maria R; De Mattos-Arruda, Leticia; Fusco, Nicola; Gomez, Patricia; Gonzalez-Cao, Maria; Lim, Raymond S; Macedo, Gabriel S et al.
DOI: 10.18632/oncotarget.25041

Connexins: Synthesis, Post-Translational Modifications, and Trafficking in Health and Disease.

PMID: 29701678
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2018
Reference: Int J Mol Sci. 2018 Apr 26;19(5). pii: ijms19051296. doi: 10.3390/ijms19051296.
Impact factor:
Publication type: Review in national publication
Authors: Aasen, Trond; Johnstone, Scott; Koval, Michael; Lynn, K Sabrina; Vidal-Brime, Laia et al.
DOI: 10.3390/ijms19051296

Phenformin-Induced Mitochondrial Dysfunction Sensitizes Hepatocellular Carcinoma for Dual Inhibition of mTOR.

PMID: 29691292
Journal: CLINICAL CANCER RESEARCH
Year: 2018
Reference: Clin Cancer Res. 2018 Aug 1;24(15):3767-3780. doi: 10.1158/1078-0432.CCR-18-0177. Epub 2018 Apr 24.
Impact factor:
Publication type: Paper in international publication
Authors: Ge, Xuemei; Hernandez-Alvarez, Maria Isabel; Hernandez-Losa, Javier; Kozma, Sara C; Mercer, Carol A; Ramon Y Cajal, Santiago; Thomas, George; Thomas, Hala Elnakat; Veiga, Sonia Rosa; Zorzano, Antonio et al.
DOI: 10.1158/1078-0432.CCR-18-0177

CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells.

PMID: 29669853
Journal: Science Translational Medicine
Year: 2018
Reference: Sci Transl Med. 2018 Apr 18;10(437). pii: 10/437/eaar6759. doi: 10.1126/scitranslmed.aar6759.
Impact factor:
Publication type: Paper in international publication
Authors: Abdel-Mohsen, Mohamed; Betts, Michael R; Buzon, Maria J; Castellvi, Josep; Cox, Kara; Del Rio Estrada, Perla M; Frank, Ian; Genesca, Meritxell; Giron, Leila B; Gonzalez-Navarro, Mauricio et al.
DOI: 10.1126/scitranslmed.aar6759

Successful multiple organ donation after donor brain death due to Actinomyces israelii meningitis.

PMID: 28429866
Journal: Transplant Infectious Disease
Year: 2017
Reference: Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12711. Epub 2017 Jun 9.
Impact factor:
Publication type: Paper in international publication
Authors: Bodro, Marta; Charco, Ramon; Lagunes, Leonel; Len, Oscar; Macias, Antonio; Martinez-Saez, Elena; Moreso, Francesc; Nuvials, F Xavier; Pont, Teresa; Pumarola, Tomas et al.
DOI: 10.1111/tid.12711

E1a is an exogenous in vivo tumour suppressor.

PMID: 28416454
Journal: CANCER LETTERS
Year: 2017
Reference: Cancer Lett. 2017 Jul 28;399:74-81. doi: 10.1016/j.canlet.2017.04.010. Epub 2017 Apr 15.
Impact factor:
Publication type: Paper in international publication
Authors: Callejas-Valera, J L; Cimas, F J; Fernandez-Aroca, D M; Garcia-Gil, E; Garcia-Olmo, D C; Gutkind, J S; Hernandez-Losa, J; Marcos, P; Melgar-Rojas, P; Ortega-Muelas, M et al.
DOI: 10.1016/j.canlet.2017.04.010

Loss of the EPH receptor B6 contributes to colorectal cancer metastasis.

PMID: 28262839
Journal: Scientific Reports
Year: 2017
Reference: Sci Rep. 2017 Mar 6;7:43702. doi: 10.1038/srep43702.
Impact factor:
Publication type: Paper in international publication
Authors: Abasolo, Ibane; Afonso, Elsa; Andretta, Elena; Arango, Diego; Bazzocco, Sarah; Bilic, Josipa; Cacci, Karina; Carton-Garcia, Fernando; de Marcondes, Priscila Guimaraes; Del Llano, Edgar et al.
DOI: 10.1038/srep43702

Role of total tumour load of sentinel lymph node on survival in early breast cancer patients.

PMID: 28254641
Journal: BREAST
Year: 2017
Reference: Breast. 2017 Jun;33:8-13. doi: 10.1016/j.breast.2017.02.011. Epub 2017 Feb 28.
Impact factor:
Publication type: Paper in international publication
Authors: Bernet, Laia; Cano, Rafael; Cazorla, Alicia; Cordoba, Alicia; Cortes, Javier; Espinosa-Bravo, Martin; Martin, Maria Dolores; Peg, Vicente; Perez-Garcia, Jose Manuel; Ramon Y Cajal, Santiago et al.
DOI: 10.1016/j.breast.2017.02.011

Combined pleomorphic xanthoastrocytoma-ganglioglioma with BRAF V600E mutation: case report.

PMID: 27015517
Journal: Journal of Neurosurgery-Pediatrics
Year: 2016
Reference: J Neurosurg Pediatr. 2016 Jul;18(1):53-7. doi: 10.3171/2016.1.PEDS15558. Epub 2016 Mar 25.
Impact factor:
Publication type: Paper in international publication
Authors: Asanza, Esteban Cordero; Cicuendez, Marta; Martinez-Ricarte, Francisco; Martinez-Saez, Elena; Sahuquillo, Juan et al.
DOI: 10.3171/2016.1.PEDS15558

DPYD Genotyping to Predict Adverse Events Following Treatment With Flourouracil-Based Adjuvant Chemotherapy in Patients With Stage III Colon Cancer: A Secondary Analysis of the PETACC-8 Randomized Clinical Trial.

PMID: 26794347
Journal: JAMA Oncology
Year: 2016
Reference: JAMA Oncol. 2016 May 1;2(5):655-662. doi: 10.1001/jamaoncol.2015.5392.
Impact factor:
Publication type: Paper in international publication
Authors: Alexandre, Philippe; Boige, Valerie; Cuyle, Pieter Jan; Faroux, Roger; Greil, Richard; Landolfi, Stefania; Laurent-Puig, Pierre; Le Malicot, Karine; Lepage, Come; Matzdorff, Axel et al.
DOI: 10.1001/jamaoncol.2015.5392

Tankyrase inhibition blocks Wnt/beta-catenin pathway and reverts resistance to PI3K and AKT inhibitors in the treatment of colorectal cancer.

PMID: 26224873
Journal: CLINICAL CANCER RESEARCH
Year: 2016
Reference: Clin Cancer Res. 2016 Feb 1;22(3):644-56. doi: 10.1158/1078-0432.CCR-14-3081. Epub 2015 Jul 29.
Impact factor:
Publication type: Paper in international publication
Authors: Argiles, Guillem; Arques, Oriol; Caratu, Ginevra; Charco, Ramon; Chicote, Irene; Dienstmann, Rodrigo; Espin, Eloy; Fernandez, Natalia; Landolfi, Stefania; Matito, Judit et al.
DOI: 10.1158/1078-0432.CCR-14-3081

Pio del Rio-Hortega: A Pioneer in the Pathology of Central Nervous System Tumors.

PMID: 26973470
Journal: Frontiers in Neuroanatomy
Year: 2016
Reference: Front Neuroanat. 2016 Mar 1;10:13. doi: 10.3389/fnana.2016.00013. eCollection 2016.
Impact factor: 3.26
Publication type: Review in international publication
Authors: Ramon Y Cajal Agueras, Santiago et al.
DOI: 10.3389/fnana.2016.00013

Disruption of the ribosomal P complex leads to stress-induced autophagy.

PMID: 26176264
Journal: AUTOPHAGY
Year: 2015
Reference: Autophagy. 2015;11(9):1499-519. doi: 10.1080/15548627.2015.1063764.
Impact factor:
Publication type: Paper in international publication
Authors: Artero-Castro, Ana; Castellvi, Josep; Feliciano, Andrea; Genestar, Monica; Leal, Jose A; LLeonart, Matilde E; Peg, Vicente; Perez-Alea, Mileidys; Ramon Y Cajal, Santiago et al.
DOI: 10.1080/15548627.2015.1063764

Pulmonary Interstitial Glycogenosis: A Reversible Underlying Condition Associated With D-Transposition of the Great Arteries and Severe Persistent Pulmonary Hypertension.

PMID: 26180171
Journal: ZYGOTE
Year: 2015
Reference: World J Pediatr Congenit Heart Surg. 2015 Jul;6(3):480-3. doi: 10.1177/2150135115577433.
Impact factor:
Publication type: Paper in international publication
Authors: Abella, Raul F; Balcells, Joan; Ferreres, Joan Carles; Gonzalez-Peris, Sebastia; Gran, Ferran; Gregoraci, Angela; Ruiz, Cesar W; Sanchez-de-Toledo, Joan et al.
DOI: 10.1177/2150135115577433

Myo5b knockout mice as a model of microvillus inclusion disease.

PMID: 26201991
Journal: SCI REP-UK
Year: 2015
Reference: Sci Rep. 2015 Jul 23;5:12312. doi: 10.1038/srep12312.
Impact factor:
Publication type: Paper in international publication
Authors: Arango, Diego; Bazzocco, Sarah; Bilic, Josipa; Carton-Garcia, Fernando; Dopeso, Higinio; Hernandez-Losa, Javier; Landolfi, Stefania; Macaya, Irati; Nieto, Rocio; Overeem, Arend W et al.
DOI: 10.1038/srep12312

ERRATUM: Genomic Analyses across Six Cancer Types Identify Basal-like Breast Cancer as a Unique Molecular Entity.

PMID: 25670223
Journal: SCI REP-UK
Year: 2015
Reference: Sci Rep. 2015 Feb 11;5:8179. doi: 10.1038/srep08179.
Impact factor:
Publication type: Paper in international publication
Authors: Adamo, Barbara; Cajal, Santiago Ramon Y; Campo, Josep Maria Del; Cortes, Javier; Dawood, Shaheenah; Fan, Cheng; Felip, Enriqueta; Galvan, Patricia; Nuciforo, Paolo; Palmer, Hector G et al.
DOI: 10.1038/srep08179

Schwannomas, benign tumors with a senescent phenotype.

PMID: 24217963
Journal: HISTOLOGY AND HISTOPATHOLOGY
Year: 2014
Reference: Histol Histopathol. 2014 Jun;29(6):721-30. Epub 2013 Nov 12.
Impact factor:
Publication type: Paper in international publication
Authors: Aizpurua, M; Bague, S; Carles, J; Hernandez-Losa, C; Lleonart, M E; Orellana, R; Ramon Y Cajal, S; Romagosa, C; Serrano, C; Simonetti, S et al.
DOI:

Cyclooxygenase-2 inhibitor suppresses tumour progression of prostate cancer bone metastases in nude mice.

PMID: 24127882
Journal: BJU INTERNATIONAL
Year: 2014
Reference: BJU Int. 2014 May;113(5b):E164-77. doi: 10.1111/bju.12503. Epub 2014 Feb 14.
Impact factor:
Publication type: Paper in international publication
Authors: Doll, Andreas; Garcia, Marta; Gomis, Roger R; Guiu, Marc; Majem, Blanca; Morote, Juan; Pedrola, Nuria; Reventos, Jaume; Rigau, Marina; Romagosa, Cleofe et al.
DOI: 10.1111/bju.12503

The reproducibility and predictive value on outcome of renal biopsies from expanded criteria donors.

PMID: 24284518
Journal: KIDNEY INTERNATIONAL
Year: 2014
Reference: Kidney Int. 2014 May;85(5):1161-8. doi: 10.1038/ki.2013.461. Epub 2013 Nov 27.
Impact factor:
Publication type: Paper in international publication
Authors: Antonieta Azancot, M; Antonieta Azancot, M; Cantarell, Carme; Montero, Angeles; Moreso, Francesc; Morote, Joan; Perello, Manel; Salcedo, Maite; Sellares, Joana; Seron, Daniel et al.
DOI: 10.1038/ki.2013.461

Regulation of protein translation and c-Jun expression by prostate tumor overexpressed 1.

PMID: 23455324
Journal: ONCOGENE
Year: 2014
Reference: Oncogene. 2014 Feb 27;33(9):1124-34. doi: 10.1038/onc.2013.51. Epub 2013 Mar 4.
Impact factor:
Publication type: Paper in international publication
Authors: Abasolo, I; Bermudo, R; Canovas, V; Castellon, E; Celia-Terrassa, T; Contreras, H; de Torres, I; Fernandez, P L; Fernandez, Y; Marques, N et al.
DOI: 10.1038/onc.2013.51

Hepatitis A virus cellular receptor 1/kidney injury molecule-1 is a susceptibility gene for clear cell renal cell carcinoma and hepatitis A virus cellular receptor/kidney injury molecule-1 ectodomain shedding a predictive biomarker of tumour progression.

PMID: 23352434
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2013
Reference: Eur J Cancer. 2013 May;49(8):2034-47. doi: 10.1016/j.ejca.2012.12.020. Epub 2013 Jan 23.
Impact factor:
Publication type: Paper in international publication
Authors: Blanco, Albert; Cuadros, Thais; de Torres, Ines; Itarte, Emilio; Lopez-Hellin, Joan; Meseguer, Anna; Messaoud, Nabil Ben; Mir, Carmen; Morote, Juan; Ramon Y Cajal, Santiago et al.
DOI: 10.1016/j.ejca.2012.12.020

Brush border myosin Ia inactivation in gastric but not endometrial tumors.

PMID: 23002058
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2013
Reference: Int J Cancer. 2013 Apr 15;132(8):1790-9. doi: 10.1002/ijc.27856. Epub 2012 Oct 20.
Impact factor:
Publication type: Paper in international publication
Authors: Alazzouzi, Hafid; Andretta, Elena; Arango, Diego; Bazzocco, Sarah; Cajal, Santiago Ramon Y; Dopeso, Higinio; Ferreira, Ana M; Gebert, Johannes; Hernandez-Losa, Javier; Hofstra, Robert M W et al.
DOI: 10.1002/ijc.27856

BRAF V600E and KRAS G12S mutations in peripheral nerve sheath tumours.

PMID: 23190154
Journal: HISTOPATHOLOGY
Year: 2013
Reference: Histopathology. 2013 Feb;62(3):499-504. doi: 10.1111/his.12021. Epub 2012 Nov 27.
Impact factor:
Publication type: Paper in international publication
Authors: Bague, Silvia; Carles, Joan; Carrato, Cristina; Hernandez-Losa, Javier; Huguet, Pere; Moline, Teresa; Orellana, Ruth; Ramon Y Cajal, Santiago; Romagosa, Cleofe; Serrano, Cesar et al.
DOI: 10.1111/his.12021

Presence of an extra chromosome alters meiotic double-stranded break repair dynamics and MLH1 foci distribution in human oocytes.

PMID: 23283390
Journal: CHROMOSOMA
Year: 2013
Reference: Chromosoma. 2013 Mar;122(1-2):93-102. doi: 10.1007/s00412-012-0394-5. Epub 2013 Jan 4.
Impact factor:
Publication type: Paper in international publication
Authors: Brieno-Enriquez, M; Cabero, Ll; Garcia Caldes, M; Garcia, R; Martin, M; Robles, P; Roig, I; Toran, N et al.
DOI: 10.1007/s00412-012-0394-5

Exploratory analysis of activation of PTEN-PI3K pathway and downstream proteins in malignant pleural mesothelioma (MPM).

PMID: 22459204
Journal: LUNG CANCER
Year: 2012
Reference: Lung Cancer. 2012 Jul;77(1):192-8. Epub 2012 Mar 27.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.lungcan.2012.02.022

Hirano body - rich subtypes of Creutzfeldt-Jakob disease.

PMID: 21726270
Journal: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
Year: 2012
Reference: Neuropathol Appl Neurobiol. 2012 Apr;38(2):153-161. doi: 10.1111/j.1365-2990.2011.01208.x.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1365-2990.2011.01208.x

Gene expression is altered after Bisphenol A exposure in human fetal oocytes in vitro.

PMID: 22121209
Journal: MOLECULAR HUMAN REPRODUCTION
Year: 2012
Reference: Mol Hum Reprod. 2012 Apr;18(4):171-83. Epub 2011 Nov 25.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1093/molehr/gar074

Generation and characterization of orthotopic murine models for endometrial cancer.

PMID: 22198674
Journal: CLINICAL & EXPERIMENTAL METASTASIS
Year: 2012
Reference: Clin Exp Metastasis. 2012 Mar;29(3):217-27. Epub 2011 Dec 25.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1007/s10585-011-9444-2

Consensus of the Spanish Society of Medical Oncology (SEOM) and Spanish Society of Pathology (SEAP) for HER2 testing in gastric carcinoma.

PMID: 21865135
Journal: Clinical & Translational Oncology
Year: 2011
Reference: Clin Transl Oncol. 2011 Sep;13(9):636-51.
Impact factor: 1.254
Publication type: Paper in national publication
Authors: Garcia-Caballero, T, Garcia-Garcia, E, Iglesias, M, Lopez, J A, Ramon Y Cajal, S, Rojo, F, Palacios, J, Vera-Sempere, F, Aranda, E, Colomer, R et al.
DOI:

Spinophilin acts as a tumor suppressor by regulating Rb phosphorylation.

PMID: 21772120
Journal: CELL CYCLE
Year: 2011
Reference: Cell Cycle. 2011 Aug 15;10(16):2751-62. Epub 2011 Aug 15.
Impact factor: 4.999
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI:

The effect of p-4E-BP1 and p-eIF4E on cell proliferation in a breast cancer model.

PMID: 21750861
Journal: INTERNATIONAL JOURNAL OF ONCOLOGY
Year: 2011
Reference: Int J Oncol. 2011 Nov;39(5):1337-45. doi: 10.3892/ijo.2011.1118. Epub 2011 Jul 8.
Impact factor: 2.571
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.3892/ijo.2011.1118

Apoptosis-like cell death induction and aberrant fibroblast properties in human incisional hernia fascia.

PMID: 21641387
Journal: AMERICAN JOURNAL OF PATHOLOGY
Year: 2011
Reference: Am J Pathol. 2011 Jun;178(6):2641-53.
Impact factor: 5.224
Publication type: Paper in international publication
Authors: Guillem-Marti, Jordi, Lopez-Cano, Manuel, Huguet, Pere, Ramon-Y-Cajal, Santiago, Reventos, Jaume, Armengol, Manel, Arbos, Maria A, Quiles, Maria T, Diaz, Ramon et al.
DOI: 10.1016/j.ajpath.2011.02.044

Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer.

PMID: 21167064
Journal: Journal of Translational Medicine
Year: 2010
Reference: J Transl Med. 2010 Dec 18;8:135. doi: 10.1186/1479-5876-8-135.
Impact factor: 3.407
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1186/1479-5876-8-135

A Major Role of p95/611-CTF, a Carboxy-Terminal Fragment of HER2, in the Down-modulation of the Estrogen Receptor in HER2-Positive Breast Cancers.

PMID: 20978202
Journal: CANCER RESEARCH
Year: 2010
Reference: Cancer Res. 2010 Nov 1;70(21):8537-46. Epub 2010 Oct 26.
Impact factor: 7.543
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1158/0008-5472.CAN-10-1701

Voltage-dependent potassium channels Kv1.3 and Kv1.5 in human fetus.

PMID: 20798505
Journal: CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
Year: 2010
Reference: Cell Physiol Biochem. 2010;26(2):219-26. Epub 2010 Aug 24.
Impact factor: 3.563
Publication type: Paper in international publication
Authors: Bielanska, Joanna, Hernandez-Losa, Javier, Moline, Teresa, Somoza, Rosa, Ramon Y Cajal, Santiago, Condom, Enric, Ferreres, Joan Carles, Felipe, Antonio et al.
DOI: 10.1159/000320528

Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment.

PMID: 20371676
Journal: CLINICAL CANCER RESEARCH
Year: 2010
Reference: Clin Cancer Res. 2010 Apr 15;16(8):2375-82. Epub 2010 Apr 6.
Impact factor: 6.747
Publication type: Paper in international publication
Authors: Dopeso, Higinio, Mateo-Lozano, Silvia, Elez, Elena, Landolfi, Stefania, Ramos Pascual, Francisco Javier, Hernandez-Losa, Javier, Mazzolini, Rocco, Rodrigues, Paulo, Bazzocco, Sarah, Carreras, Maria Josep et al.
DOI: 10.1158/1078-0432.CCR-09-3275

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.

PMID: 19483674
Journal: NATURE
Year: 2009
Reference: Nature. 2009 Jul 2;460(7251):53-9. doi: 10.1038/nature08129. Epub 2009 May 31.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Barrero, Maria Jose; Bueren, Juan; Castella, Maria; Consiglio, Antonella; Garreta, Elena; Gonzalez, Federico; Guenechea, Guillermo; Izpisua Belmonte, Juan Carlos; Navarro, Susana et al.
DOI: 10.1038/nature08129

[Karnosfsky index as a mortality predicting factor in patients on home-based enteral nutrition].

PMID: 19593485
Journal: Nutricion Hospitalaria
Year: 2009
Reference: Nutr Hosp. 2009 Mar-Apr;24(2):156-60.
Impact factor: 1.096
Publication type: Paper in national publication
Authors: Puiggros, C, Lecha, M, Rodriguez, T, Perez-Portabella, C, Planas, M et al.
DOI:

[Nutritional support in the home-based hospitalization setting].

PMID: 19266120
Journal: Nutricion Hospitalaria
Year: 2009
Reference: Nutr Hosp. 2009 Jan-Feb;24(1):93-6.
Impact factor: 1.096
Publication type: Paper in national publication
Authors: Chicharro, L, Planas, M, Perez-Portabella, C, Velez, C, San Jose, A et al.
DOI:

[Immediate complications of feeding percutaneous gastrostomy: a 10-year experience].

PMID: 19266117
Journal: Nutricion Hospitalaria
Year: 2009
Reference: Nutr Hosp. 2009 Jan-Feb;24(1):73-6.
Impact factor: 1.096
Publication type: Paper in national publication
Authors: Perez-Portabella, C, Planas, M, Cots, I, Puiggros, C, Chicharro, L et al.
DOI:

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