Catálogo de modelos animales del Vall d'Hebron Barcelona Hospital Campus
Utiliza el buscador para encontrar los modelos que necesitas para tu investigación.
Reference
Name
Animal specie
Strain
Thematic area
Specific pathology
Description
AT002
Aneurysm model
Pig (Sus scrofa)
Cardiovascular diseases
Aneurysm
Endovascular treatment of carotid aneurysms
AT121
APP23 model Alzheimer Cerebral Beta-amyloidosis
Mice (Mus musculus)
C57BL/6 APP23
Neurovascular diseases
Alzheimer and Sporadic Cerebral Amyloid Angiopathy
This model characterizes Alzheimer's disease (AD) in which parenchymal Aβ deposits are observed and Cerebral Amyloid Angiopathy (CAA) characterized by the presence of beta-amyloid deposits in cerebral vessels and found in 80% of patients. Alzheimer's patients. Characterized by the overexpression of the Amyloid Precursor Protein (APP) gene containing the APP K670N/M671L double mutation (hAPP751 – Sweedish double-mutation) under the control of the Thy1 neuronal promoter (Sturchler-Pierrat, C. et al., 1997).
AT005
Bone Defects in metaphysis (cylindrical)
Sheep (Ovis Linnaeus)
Ripollesa
Orthopedic
Bone regeneration
The defects will be located in the medial and lateral distal metaphysis of the femur and in the medial and lateral proximal metaphysis of the tibia at the level of the physis mark.
AT006
Caloric Restriction
Mice (Mus musculus)
C567BL/6
Endocrinology
Disorders of body’s energy balance; Obesity; Type 2 diabetes
In this model, mice are subjected to a 40% caloric restriction compared to their ad libitum fed littermates. 60% of the food eaten by ad libitum fed littermates is provided to individually-caged calorie restricted mice.
AT007
Cancer models
Mice (Mus musculus)
SCID/Beige NOD.SCID
Oncology
Oncology & Immuno-Oncology
Tumor cells or tumor fragments implanted subcutaneously
AT122
Cardiac Ischemia mouse model
Mice (Mus musculus)
C57BL/6J
Cardiovascular diseases
Cardiac Ischemia
Model generated by myocardial infarction induction
AT123
Cardiac Ischemia pig model
Pig (Sus scrofa)
Cardiovascular diseases
Cardiac Ischemia
Model generated by myocardial infarction induction
AT124
Cardiac Ischemia rat model
Rat (Rattus norvegicus)
Sprague Dawley®
Cardiovascular diseases
Cardiac Ischemia
Model generated by myocardial infarction induction
AT125
Cardiac Ischemia-Reperfussion mouse model
Mice (Mus musculus)
C57BL/6J
Cardiovascular diseases
Cardiac Ischemia, reperfussion
Myocardial infarction followed by reperfussion
AT126
Cardiac Ischemia-Reperfussion pig model
Pig (Sus scrofa)
Cardiovascular diseases
Ischemia/reperfussion
Myocardial infarction followed by reperfussion
Solicitud de modelos animales
Este catálogo se actualiza anualmente. Para información adicional y/o solicitar modelos animales, puedes ponerte en contacto con nosotros en catalogo.animales@vhir.org.