Pasar al contenido principal

Juan Angel Recio Conde

Dr Recio is the Head of the BioMedical Research in Melanoma-Animal Models in Cancer Group at VHIR. His group is very interested in skin cancer. He investigates the molecular causes for these diseases in order to design effective therapies against them. This is done in close proximity to patients where our goal is to translate our discoveries as fast as possible to patients. Consequently, He have a multidisciplinary group that associate dermatologists, oncologists, pathologists and basic-scientists that ask relevant clinical questions that need biological answers. His workflow contemplates reverse translation where information obtained from patients (tumors deep sequencing, immunohistochemistry, clinical history...etc) is translated into animal models and in vitro experiments in order to answer relevant questions. These results are used to design new therapeutic approaches and preclinical studies that ultimately will be translated to patients. This cooperation with the clinic started back in 2007 when he formed a translational group devoted to solve relevant problems in the clinic, which includes conceptual basic mechanisms that can be translated to the patients. In the last ten years with the arrival of the immunotherapy he created the Melanoma Taskforce, a joined effort that puts together oncologists and basic researchers from different fields (immunology, genomics, imaging, etc.) from VHIR, VHIO and the Hospital, with the goal of translate the knowledge to patients through the daily practice, and the cooperation with the industry to improve the efficacy of novel drugs or combinations in clinical trials. His group face problems that start in the primary lesions through the most advance stages of the disease, including samples from clinical trials and different studies. With this structure he has managed to establish a coordinated network within the hospital to develop patient derived xenografts (PDX) from fresh tissue samples and a Biobank of melanoma, saving valuable different type of samples which are the source of information for his research and discoveries.

Instituciones de las que forman parte

Jefe de grupo
Investigación Biomédica en Melanoma
Vall Hebron Institut de Recerca

Juan Angel Recio Conde

Instituciones de las que forman parte

Jefe de grupo
Investigación Biomédica en Melanoma
Vall Hebron Institut de Recerca

Dr Recio is the Head of the BioMedical Research in Melanoma-Animal Models in Cancer Group at VHIR. His group is very interested in skin cancer. He investigates the molecular causes for these diseases in order to design effective therapies against them. This is done in close proximity to patients where our goal is to translate our discoveries as fast as possible to patients. Consequently, He have a multidisciplinary group that associate dermatologists, oncologists, pathologists and basic-scientists that ask relevant clinical questions that need biological answers. His workflow contemplates reverse translation where information obtained from patients (tumors deep sequencing, immunohistochemistry, clinical history...etc) is translated into animal models and in vitro experiments in order to answer relevant questions. These results are used to design new therapeutic approaches and preclinical studies that ultimately will be translated to patients. This cooperation with the clinic started back in 2007 when he formed a translational group devoted to solve relevant problems in the clinic, which includes conceptual basic mechanisms that can be translated to the patients. In the last ten years with the arrival of the immunotherapy he created the Melanoma Taskforce, a joined effort that puts together oncologists and basic researchers from different fields (immunology, genomics, imaging, etc.) from VHIR, VHIO and the Hospital, with the goal of translate the knowledge to patients through the daily practice, and the cooperation with the industry to improve the efficacy of novel drugs or combinations in clinical trials. His group face problems that start in the primary lesions through the most advance stages of the disease, including samples from clinical trials and different studies. With this structure he has managed to establish a coordinated network within the hospital to develop patient derived xenografts (PDX) from fresh tissue samples and a Biobank of melanoma, saving valuable different type of samples which are the source of information for his research and discoveries.

Dr. Recio obtained her PhD at the University Autonomous of Madrid investigating the immunophenotype of the epididymis during development and in inflammatory diseases. During the same period of time he worked simultaneously at Dr Ana Aranda’s lab (IIB , CSIC) investigating the biological consequences of nuclear receptors regulation by retinoic acid and visited Dr. Notario’s Lab at Georgetown University (Washington DC, USA) where he studied the contribution of dioxins to breast cancer development. Then, he moved to Georgetown University as a postdoctoral where he spent almost three years studying the oncogenic transformation of cells. He did his second postdoctoral training at the National Cancer Institute (NIH, Bethesda, MD, USA) joining Dr. Glenn Merlino’s lab where he studied the molecular basis of melanoma and develop the first mouse model of UV-induced melanoma. During this time, he also was involved in the development of other mouse models including the first rhabdomyosarcoma mouse model. Then, he obtained a Ramon y Cajal award and moved to Barcelona where he started his own lab at the Vall d’Hebron Institute of Oncology (VHIO), establishing a translational group of Biomedical Research in Melanoma, later in 2010 he moved to VHIR. Dr Recio have published more than 40 papers mostly in the melanoma filed, 2 books chapters and have continuously obtained a number of competitive national and international grants over the last 20 years, frequently collaborating with the industry. In addition to this he has directed 6 doctoral thesis and supervised more than 20 master projects. He belongs to the biomedicine postgraduate program at the University of Barcelona and the Translational Master at the Vall d’Hebron Institute (University Autonomous of Barcelona). Moreover, he is an expert evaluator for national and International recognized Institutions and Agencies and a member of several scientific and technical boards and committees.

Proyectos

Unraveling metabolic settings and targeting metabolic enzymes with selective lethality in BRAF and NRAS mutant melanoma tumors (METABOSET) Grant agreement nº 627869

IP: Juan Angel Recio Conde
Colaboradores: -
Entidad financiadora: EUROPEAN COMMISSION
Financiación: 173370.6
Referencia: METABOSET_FP7PEOPLE-IEF2013
Duración: 01/04/2014 - 31/03/2016

Estudio de la función de LKB1 y de los mutantes asociados a melanoma dirigido a la creación de terapias personalizadas efectivas

IP: Juan Angel Recio Conde
Colaboradores: -
Entidad financiadora: Instituto de Salud Carlos III
Financiación: 167541.44
Referencia: PI11/00384
Duración: 01/01/2012 - 28/02/2015

Papel de LKB1 en respuesta a factores de crecimiento y en el desarrollo y progresión del melanoma

IP: Juan Angel Recio Conde
Colaboradores: Anna Pujol Esclusa
Entidad financiadora: Instituto de Salud Carlos III
Financiación: 225907
Referencia: PI080653
Duración: 01/01/2009 - 31/03/2012

Role of methylation in MAPK signal transduction pathways.

IP: Juan Angel Recio Conde
Colaboradores: -
Entidad financiadora: Agència Gestió Ajuts Universitaris i de Recerca
Financiación: 60147.96
Referencia: 2011FI_B2 00205
Duración: 30/01/2009 - 29/01/2012

Noticias relacionadas

En el Día Mundial de la Investigación en Cáncer, destacamos el modelo de investigación oncológica del VHIR que permite que los resultados del laboratorio se trasladen lo más rápido posible a la práctica clínica.

Hemos superado una exhaustiva evaluación externa de la OECI que nos acredita como centro de excelencia en la asistencia multidisciplinaria a los pacientes oncológicos, investigación, prevención, innovación y formación de los profesionales.

El Dr. Vicente García-Patos recibió la distinción a la mejor trayectoria profesional y su equipo, un premio a la mejor comunicación oral y un primer accésit al mejor póster de oncología.

Profesionales relacionados

Francesc Xavier Serra Marin

Francesc Xavier Serra Marin

Auxiliar de investigación
Investigación Biomédica en Ginecología
Leer más
Anna Sole Fores

Anna Sole Fores

Técnico de investigación
Donación y Trasplante de órganos, tejidos y células
Leer más
Concepción Castro Pérez

Concepción Castro Pérez

Administrativo/va
Unidad de Contabilidad e Ingresos
Área de Finanzas
Leer más
Clara Irati Fernandez Diez

Clara Irati Fernandez Diez

Tècnic/a de Laboratori
Biobanco
Core Facilities Clínicos
Área de Core Facilities
Leer más

Suscríbete a nuestros boletines y forma parte de la vida del Campus

Vall d'Hebron Barcelona Hospital Campus es un parque de referencia mundial donde la asistencia, la investigación, la docencia y la innovación se dan la mano.