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Cardiovascular Diseases

Cardiovascular Diseases group is a translational research group within the Cardiology Department of Vall d’Hebron Hospital that performs laboratory, clinical and epidemiological research. In the CIBERCV network we are within the topic of descriptor 2 “Arterial disease, thrombosis and myocardial ischemia-reperfusion injury”. Our contributions in these topics address the following lines: 

  • Myocardial ischemia-reperfusion injury (i.e. mechanisms of endogenous cardioprotection, ischemic conditioning and remodeling), 
  • Coronary artery disease (i.e. genetic factors involved in coronary artery disease, determinants of thrombotic complications and prognosis), 
  • Aortic diseases (i.e. determinants of aorta dilatation, aortic biomechanics abnormalities in Marfan´s syndrome, and new imaging methods), 
  • Congenital/familiar heart diseases (i.e. genetic determinants and prognosis factors). 

In the CIBERESP network, our group is interested in the study of effectiveness/cost-effectiveness of cardiovascular interventions, health outcome research and methods in clinical research. The group has 19 principal investigators, 32 active projects and clinical trial and has been done 142 publications in 2020.

Publications

Coronary artery fistulas after paediatric heart transplantation.

PMID: 34321120
Journal: CARDIOLOGY IN THE YOUNG
Year: 2022
Reference: Cardiol Young. 2022 Feb;32(2):312-314. doi: 10.1017/S1047951121002729. Epub 2021 Jul 29.
Impact factor: 1.093
Publication type: Paper in international publication
Authors: Camprubi-Tubella, Elisabet; Gran-Ipina, Ferran; Betrian-Blasco, Pedro et al.
DOI: 10.1017/S1047951121002729

Assessment of medical management in Coronary Type 2 Diabetic patients with previous percutaneous coronary intervention in Spain: A retrospective analysis of electronic health records using Natural Language Processing.

PMID: 35143527
Journal: PLoS One
Year: 2022
Reference: PLoS One. 2022 Feb 10;17(2):e0263277. doi: 10.1371/journal.pone.0263277. eCollection 2022.
Impact factor: 3.24
Publication type: Paper in international publication
Authors: Barrios, Vivencio; Nunez-Gil, Ivan; Gomez-Doblas, Juan Josa; Garcia-Moll, Xavier; Lafuente-Gormaz, Carlos; Rollan-Gomez, Maria Jesus; Peral-Disdie, Vicente; Martinez-Dolz, Luis; Rodriguez-Santamarta, Miguel; Vinolas-Prat, Xavier et al.
DOI: 10.1371/journal.pone.0263277

Vein of Galen aneurysm, dilated cardiomyopathy, and slender habitus in a patient with a recurrent pathogenic variant in PACS2.

PMID: 34894068
Journal: AMERICAN JOURNAL OF MEDICAL GENETICS PART A
Year: 2022
Reference: Am J Med Genet A. 2022 Mar;188(3):991-995. doi: 10.1002/ajmg.a.62596. Epub 2021 Dec 11.
Impact factor: 2.802
Publication type: Paper in international publication
Authors: Valenzuela, Irene; Guillen Benitez, Elena; Sanchez-Montanez, Angel; Limeres, Javier; Lopez-Grondona, Fermina; Cusco, Ivon; Tizzano, Eduardo F et al.
DOI: 10.1002/ajmg.a.62596

Registration-based semi-automatic assessment of aortic diameter growth rate from contrast-enhanced computed tomography outperforms manual quantification.

PMID: 34655311
Journal: EUROPEAN RADIOLOGY
Year: 2022
Reference: Eur Radiol. 2022 Mar;32(3):1997-2009. doi: 10.1007/s00330-021-08273-2. Epub 2021 Oct 16.
Impact factor: 5.315
Publication type: Paper in international publication
Authors: Dux-Santoy, Lydia; Rodriguez-Palomares, Jose F; Teixido-Tura, Gisela; Ruiz-Munoz, Aroa; Casas, Guillem; Valente, Filipa; Servato, Maria Luz; Galian-Gay, Laura; Gutierrez, Laura; Gonzalez-Alujas, Teresa et al.
DOI: 10.1007/s00330-021-08273-2

Current options and recommendations for the use of thoracic endovascular aortic repair in acute and chronic thoracic aortic disease: an expert consensus document of the European Society for Cardiology (ESC) Working Group of Cardiovascular Surgery, the ESC Working Group on Aorta and Peripheral Vascular Diseases, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the European Association for Cardio-Thoracic Surgery (EACTS).

PMID: 33011773
Journal: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
Year: 2021
Reference: Eur J Cardiothorac Surg. 2021 Jan 4;59(1):65-73. doi: 10.1093/ejcts/ezaa268.
Impact factor:
Publication type: Paper in international publication
Authors: Aboyans, Victor; Al-Attar, Nawwar; Braverman, Alan C; Czerny, Martin; de Paulis, Ruggero; Di Marco, Luca; Eagle, Kim; Eggebrecht, Holger; Evangelista, Arturo; Falk, Volkmar et al.
DOI: 10.1093/ejcts/ezaa268

Typical angina, atypical angina, and atypical chest pain: is it time to change this terminology?

PMID: 33221179
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2021
Reference: Rev Esp Cardiol (Engl Ed). 2021 Jan;74(1):118-119. doi: 10.1016/j.rec.2020.10.006. Epub 2020 Nov 19.
Impact factor:
Publication type: Letter or abstract
Authors: Barrabes, Jose A; Sagrista-Sauleda, Jaume et al.
DOI: 10.1016/j.rec.2020.10.006

Predicting sudden cardiac death in adults with congenital heart disease.

PMID: 32546506
Journal: HEART
Year: 2021
Reference: Heart. 2021 Jan;107(1):67-75. doi: 10.1136/heartjnl-2020-316791. Epub 2020 Jun 16.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Andres; Alonso, Andres; Avila, Pablo; Avila, Pablo; Bastos-Fernandez, Maria; Bermejo, Javier; Bermejo, Javier; Bouzas-Zubeldia, Beatriz; Buendia, Francisco; Cano-Nieto, Joaquin et al.
DOI: 10.1136/heartjnl-2020-316791

Safety and efficacy of non-vitamin K antagonist oral anticoagulants for prevention of thromboembolism in adults with systemic right ventricle: Results from the NOTE international registry.

PMID: 32805330
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2021
Reference: Int J Cardiol. 2021 Jan 1;322:129-134. doi: 10.1016/j.ijcard.2020.08.034. Epub 2020 Aug 14.
Impact factor:
Publication type: Paper in international publication
Authors: Aboulhosn, Jamil; Alonso-Gonzalez, Rafael; Bouchardy, Judith; Bouma, Berto J; Broberg, Craig S; Budts, Werner; Dimopoulos, Konstantinos; Egbe, Alexander C; Fernandes, Susan M; Fusco, Flavia et al.
DOI: 10.1016/j.ijcard.2020.08.034

The conventional isoproterenol-induced heart failure model does not consistently mimic the diaphragmatic dysfunction observed in patients.

PMID: 32730329
Journal: PLoS One
Year: 2020
Reference: PLoS One. 2020 Jul 30;15(7):e0236923. doi: 10.1371/journal.pone.0236923. eCollection 2020.
Impact factor: 2.74
Publication type: Paper in international publication
Authors: Cabrera-Aguilera, Ignacio, Falcones, Bryan, Calvo-Fernandez, Alicia, Benito, Begona, Barreiro, Esther, Gea, Joaquim, Farre, Ramon, Almendros, Isaac, Farre, Nuria et al.
DOI: 10.1371/journal.pone.0236923

Safety and efficacy of drug eluting stents vs bare metal stents in patients with atrial fibrillation: A systematic review and meta-analysis.

PMID: 32688097
Journal: THROMBOSIS RESEARCH
Year: 2020
Reference: Thromb Res. 2020 Nov;195:128-135. doi: 10.1016/j.thromres.2020.07.010. Epub 2020 Jul 9.
Impact factor: 2.869
Publication type: Review in international publication
Authors: Banach, Maciej, Bueno, Hector, Hernandez, Adrian V, Ruiz-Nodar, Juan M, Raber, Lorenz, Fauchier, Laurent, Kiviniemi, Tuomas, Rello, Pau, Soriano, Toni, Bhatt, Deepak L et al.
DOI: 10.1016/j.thromres.2020.07.010

Conservative vs surgical treatment in type A intramural hematoma. What is new?

PMID: 32652656
Journal: JOURNAL OF CARDIAC SURGERY
Year: 2020
Reference: J Card Surg. 2020 Aug;35(8):1758-1760. doi: 10.1111/jocs.14739. Epub 2020 Jul 11.
Impact factor: 1.49
Publication type: Editorail in international publication
Authors: Moral, Sergio, Ballesteros, Esther, Evangelista, Arturo et al.
DOI: 10.1111/jocs.14739

Ductal stenting and pulmonary artery stenosis.

PMID: 31831301
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2020
Reference: Rev Esp Cardiol (Engl Ed). 2020 Jul;73(7):578. doi: 10.1016/j.rec.2019.10.014. Epub 2019 Dec 10.
Impact factor: 4.642
Publication type: Paper in national publication
Authors: Betrian Blasco, Pedro, Marti Aguasca, Gerard, Ferrer Menduina, Queralt et al.
DOI: 10.1016/j.rec.2019.10.014

Cardiologists and the Cardiology of the Future. Vision and proposals of the Spanish Society of Cardiology for the cardiology of the 21st century.

PMID: 31311762
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Aug;72(8):649-657. doi: 10.1016/j.rec.2019.02.025. Epub 2019 Jul 13.
Impact factor: 5.078
Publication type: Paper in national publication
Authors: Sanchez, Manuel Anguita, Martin, Joaquin J Alonso, Fillat, Angel Cequier, Doblas, Juan Jose Gomez, Rivera, Luis Pulpon, Goya, Inaki Lekuona, Rodrigo, Francisco Rodriguez, Romo, Andres Iniguez, Miguel, Carlos Macaya, Masip, Arturo Evangelista et al.
DOI: 10.1016/j.rec.2019.02.025

Percutaneous cardiological intervention and cardiac surgery: patient-centered care. Position statement of the Spanish Society of Cardiology.

PMID: 31262700
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Aug;72(8):658-663. doi: 10.1016/j.rec.2019.02.024. Epub 2019 Jun 28.
Impact factor: 5.078
Publication type: Paper in national publication
Authors: Cosin-Sales, Juan, Lopez de Sa, Esteban, Evangelista, Artur, Bueno, Hector, Anguita, Manuel, Moreno, Raul, Perez de Prado, Armando, Cequier, Angel et al.
DOI: 10.1016/j.rec.2019.02.024

Trial protocol for the validation of the 'Toronto Aortic Stenosis Quality of Life (TASQ) Questionnaire' in patients undergoing surgical aortic valve replacement (SAVR) or transfemoral (TF) transcatheter aortic valve implantation (TAVI): the TASQ registry.

PMID: 31218003
Journal: Open heart
Year: 2019
Reference: Open Heart. 2019 May 21;6(1):e001008. doi: 10.1136/openhrt-2019-001008. eCollection 2019.
Impact factor: 0
Publication type: Paper in international publication
Authors: Frank, Derk, Kennon, Simon, Bonaros, Nikolaos, Romano, Mauro, Lefevre, Thierry, Di Mario, Carlo, Stefano, Pierluigi, Ribichini, Flavio Luciano, Himbert, Dominique, Urena-Alcazar, Marina et al.
DOI: 10.1136/openhrt-2019-001008

Successful percutaneous closure of a complete unroofed coronary sinus.

PMID: 31208855
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Nov;72(11):970-972. doi: 10.1016/j.rec.2019.03.014. Epub 2019 Jun 15.
Impact factor: 5.078
Publication type: Paper in international publication
Authors: Figueras-Coll, Marc, Sabate-Rotes, Anna, Giralt-Garcia, Gemma, Marti-Aguasca, Gerard, Betrian-Blasco, Pedro et al.
DOI: 10.1016/j.rec.2019.03.014

Phenotype-modifying Factors in Hypertrophic Cardiomyopathy.

PMID: 29844006
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2018
Reference: Rev Esp Cardiol (Engl Ed). 2018 Sep;71(9):770. doi: 10.1016/j.rec.2018.03.021. Epub 2018 May 26.
Impact factor: 5.166
Publication type: Letter or abstract
Authors: Limeres Freire, Javier et al.
DOI: 10.1016/j.rec.2018.03.021

3-Year Clinical Follow-Up of the RIBS IV Clinical Trial: A Prospective Randomized Study of Drug-Eluting Balloons Versus Everolimus-Eluting Stents in Patients With In-Stent Restenosis in Coronary Arteries Previously Treated With Drug-Eluting Stents.

PMID: 29798776
Journal: JACC-Cardiovascular Interventions
Year: 2018
Reference: JACC Cardiovasc Interv. 2018 May 28;11(10):981-991. doi: 10.1016/j.jcin.2018.02.037.
Impact factor: 9.881
Publication type: Clinical Trials
Authors: Alfonso, Fernando, Perez-Vizcayno, Maria Jose, Cuesta, Javier, Garcia Del Blanco, Bruno, Garcia-Touchard, Arturo, Lopez-Minguez, Jose Ramon, Masotti, Monica, Zueco, Javier, Cequier, Angel, Velazquez, Maite et al.
DOI: 10.1016/j.jcin.2018.02.037

Mechanical dyssynchrony according to validated cut-off values using gated SPECT myocardial perfusion imaging.

PMID: 28150153
Journal: JOURNAL OF NUCLEAR CARDIOLOGY
Year: 2018
Reference: J Nucl Cardiol. 2018 Jun;25(3):1039. doi: 10.1007/s12350-017-0791-5. Epub 2017 Feb 1.
Impact factor: 3.847
Publication type: Letter or abstract
Authors: Aguade-Bruix, Santiago, Romero-Farina, Guillermo et al.
DOI: 10.1007/s12350-017-0791-5

The Jarisch-Herxheimer reaction in syphilis: could molecular typing help to understand it better?

PMID: 29775498
Journal: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Year: 2018
Reference: J Eur Acad Dermatol Venereol. 2018 Oct;32(10):1791-1795. doi: 10.1111/jdv.15078. Epub 2018 Jun 8.
Impact factor: 4.287
Publication type: Paper in international publication
Authors: Alvarez, A, Armegol, P, Barbera, M J, Esperalba, J, Vall-Mayans, M, Mota-Foix, M, Fernandez, C, Arando, M et al.
DOI: 10.1111/jdv.15078

Randomized comparison between the invasive and conservative strategies in comorbid elderly patients with non-ST elevation myocardial infarction.

PMID: 27423981
Journal: European Journal of Internal Medicine
Year: 2016
Reference: Eur J Intern Med. 2016 Nov;35:89-94. doi: 10.1016/j.ejim.2016.07.003. Epub 2016 Aug 8.
Impact factor: 2.591
Publication type: Paper in international publication
Authors: Sanchis, Juan, Nunez, Eduardo, Barrabes, Jose Antonio, Marin, Francisco, Consuegra-Sanchez, Luciano, Ventura, Silvia, Valero, Ernesto, Roque, Merce, Bayes-Genis, Antoni, Del Blanco, Bruno Garcia et al.
DOI: 10.1016/j.ejim.2016.07.003

Different prognosis according to different clinical, electrocardiographic and scintigraphic ischemia criteria.

PMID: 27336193
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2016
Reference: Int J Cardiol. 2016 Sep 15;219:240-6. doi: 10.1016/j.ijcard.2016.06.042. Epub 2016 Jun 16.
Impact factor: 4.638
Publication type: Paper in international publication
Authors: Romero-Farina, Guillermo, Candell-Riera, Jaume, Aguade-Bruix, Santiago, Pizzi, Maria N, Garcia-Dorado, David et al.
DOI: 10.1016/j.ijcard.2016.06.042

Chagas Cardiomyopathy: Usefulness of EKG and Echocardiogram in a Non-Endemic Country.

PMID: 27308824
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Jun 16;11(6):e0157597. doi: 10.1371/journal.pone.0157597. eCollection 2016.
Impact factor: 3.057
Publication type: Paper in international publication
Authors: Sanchez-Montalva, Adrian, Salvador, Fernando, Rodriguez-Palomares, Jose, Sulleiro, Elena, Sao-Aviles, Augusto, Roure, Silvia, Valerio, Lluis, Evangelista, Arturo, Molina, Israel et al.
DOI: 10.1371/journal.pone.0157597

Multimodality Assessment of Ascending Aortic Diameters: Comparison of Different Measurement Methods.

PMID: 27288090
Journal: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
Year: 2016
Reference: J Am Soc Echocardiogr. 2016 Sep;29(9):819-826.e4. doi: 10.1016/j.echo.2016.04.006. Epub 2016 Jun 7.
Impact factor: 4.254
Publication type: Paper in international publication
Authors: Rodriguez-Palomares, Jose F, Teixido-Tura, Gisela, Galuppo, Valentina, Cuellar, Hug, Laynez, Ana, Gutierrez, Laura, Gonzalez-Alujas, Maria Teresa, Garcia-Dorado, David, Evangelista, Arturo et al.
DOI: 10.1016/j.echo.2016.04.006

Aortic Arch Mycotic Aneurysm Due to Scedosporium Apiospermum Reconstructed With Homografts.

PMID: 26046885
Journal: ANNALS OF THORACIC SURGERY
Year: 2015
Reference: Ann Thorac Surg. 2015 Jun;99(6):2218-20. doi: 10.1016/j.athoracsur.2014.08.067.
Impact factor: 3.849
Publication type: Paper in international publication
Authors: Blasco-Lucas, Arnau, Reyes-Juarez, Jose Luis, Nazarena Pizzi, Maria, Permanyer, Eduard, Evangelista, Arturo, Galinanes, Manuel et al.
DOI: 10.1016/j.athoracsur.2014.08.067

[Spanish Interdisciplinary Committee for Cardiovascular Disease Prevention and the Spanish Society of Cardiology Position Statement on Dyslipidemia Management. Differences Between the European and American Guidelines].

PMID: 26179969
Journal: Journal of the European Optical Society-Rapid Publications
Year: 2015
Reference: Hipertens Riesgo Vasc. 2015 Apr-Jun;32(2):83-91. doi: 10.1016/j.hipert.2014.09.002. Epub 2014 Nov 14.
Impact factor: 1.231
Publication type: Paper in international publication
Authors: Lobos Bejarano, Jose Maria, Galve, Enrique, Royo-Bordonada, Miguel Angel, Alegria Ezquerra, Eduardo, Armario, Pedro, Brotons Cuixart, Carlos, Cordero Fort, Alberto, Maiques Galan, Antonio, Mantilla Morato, Teresa, Perez Perez, Antonio et al.
DOI: 10.1016/j.hipert.2014.09.002

[Changing the paradigm: valsartan-inhibitor of neprilysin, a new dual-acting drug for arterial hypertension and heart failure].

PMID: 26179851
Journal: Journal of the European Optical Society-Rapid Publications
Year: 2015
Reference: Hipertens Riesgo Vasc. 2015 Jan-Mar;32(1):1-5. doi: 10.1016/j.hipert.2014.11.001. Epub 2014 Dec 15.
Impact factor: 1.231
Publication type: Paper in national publication
Authors: Galve, E, Casas-Masnou, G, Garcia-Dorado, D et al.
DOI: 10.1016/j.hipert.2014.11.001

Low-gradient Severe Aortic Stenosis With Preserved Ejection Fraction. A Pathophysiologic Entity or a Methodologic Disparity?

PMID: 26144870
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2015
Reference: Rev Esp Cardiol (Engl Ed). 2015 Aug;68(8):649-52. doi: 10.1016/j.rec.2015.04.007. Epub 2015 Jul 3.
Impact factor: 3.792
Publication type: Paper in national publication
Authors: Evangelista, Arturo, Galian, Laura et al.
DOI: 10.1016/j.rec.2015.04.007

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The consensus document is the result of multidisciplinary work that takes into account the risks associated with all stages of women's lives and the differences compared to men.

The study, which involved Vall d'Hebron, developed an action plan to efficiently allocate resources to patients most at risk of suffering this complication.

In light of this evidence, hospitals such as Vall d'Hebron have already started to include warnings about environmental pollution in their hospital discharge plans after a myocardial infarction.