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Cardiovascular Diseases

Cardiovascular Diseases group is a translational research group within the Cardiology Department of Vall d’Hebron Hospital that performs laboratory, clinical and epidemiological research. In the CIBERCV network we are within the topic of descriptor 2 “Arterial disease, thrombosis and myocardial ischemia-reperfusion injury”. Our contributions in these topics address the following lines: 

  • Myocardial ischemia-reperfusion injury (i.e. mechanisms of endogenous cardioprotection, ischemic conditioning and remodeling), 
  • Coronary artery disease (i.e. genetic factors involved in coronary artery disease, determinants of thrombotic complications and prognosis), 
  • Aortic diseases (i.e. determinants of aorta dilatation, aortic biomechanics abnormalities in Marfan´s syndrome, and new imaging methods), 
  • Congenital/familiar heart diseases (i.e. genetic determinants and prognosis factors). 

In the CIBERESP network, our group is interested in the study of effectiveness/cost-effectiveness of cardiovascular interventions, health outcome research and methods in clinical research. The group has 19 principal investigators, 32 active projects and clinical trial and has been done 142 publications in 2020.

Publications

Bioactive or Drug Eluting Stents in 75 years or older patients: The BIODES-75 Registry.

PMID: 35151602
Journal: Cardiovascular revascularization medicine : including molecular interventions
Year: 2022
Reference: Cardiovasc Revasc Med. 2022 Feb 8. pii: S1553-8389(22)00056-2. doi: 10.1016/j.carrev.2022.02.001.
Impact factor: 0
Publication type: Paper in international publication
Authors: Morales-Ponce, Francisco J; Portero-Portaz, Juan Jose; Melehi El Assali, Driss; Cerrato-Garcia, Pablo; Jimenez-Mazuecos, Jesus; Cascon, Jose Domingo; Serra, Bernat; Jerez-Valero, Miguel; Cordoba-Soriano, Juan G; Gutierrez-Diez, Antonio et al.
DOI: 10.1016/j.carrev.2022.02.001

Multimodality Cardiac Imaging in Cardiomyopathies: From Diagnosis to Prognosis.

PMID: 35160031
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Jan 24;11(3). pii: jcm11030578. doi: 10.3390/jcm11030578.
Impact factor: 4.242
Publication type: Review in international publication
Authors: Rodriguez-Palomares, Jose F; Casas, Guillem et al.
DOI: 10.3390/jcm11030578

Aortic events in pregnant patients with Marfan syndrome. Lessons from a multicenter study.

PMID: 34481752
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2022
Reference: Rev Esp Cardiol (Engl Ed). 2022 Jul;75(7):552-558. doi: 10.1016/j.rec.2021.07.012. Epub 2021 Sep 2.
Impact factor: 4.753
Publication type: Paper in national publication
Authors: Forteza, Alberto; Villarreal, Juan; Martinez, Daniel; Monivas, Vanessa; Mingo, Susana; Ospina, Victor; Serrano-Fiz, Santiago; Villar, Susana; Teixido, Gisella; Evangelista, Arturo et al.
DOI: 10.1016/j.rec.2021.07.012

Association of age with clinical features and ablation outcomes of paroxysmal supraventricular tachycardias.

PMID: 34635482
Journal: HEART
Year: 2022
Reference: Heart. 2022 Jun 24;108(14):1107-1113. doi: 10.1136/heartjnl-2021-319685.
Impact factor: 5.994
Publication type: Paper in international publication
Authors: Avila, Pablo; Calvo, David; Tamargo, Maria; Uribarri, Aitor; Datino, Tomas; Arenal, Angel; Atienza, Felipe; Soto, Nina; Fernandez-Aviles, Francisco; Gonzalez-Torrecilla, Esteban et al.
DOI: 10.1136/heartjnl-2021-319685

Cardiac biometric variables and arrhythmic events during COVID-19 pandemic lockdown in patients with an implantable cardiac monitor for syncope work-up.

PMID: 36569267
Journal:
Year: 2021
Reference: Med Clin (Engl Ed). 2021 May 21;156(10):496-499. doi: 10.1016/j.medcle.2020.12.017. Epub 2021 May 14.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Belahnech, Yassin; Benito, Begona; Ferreira-Gonzalez, Ignacio; Francisco-Pascual, Jaume; Perez-Rodon, Jordi; Rivas-Gandara, Nuria; Santos-Ortega, Alba et al.
DOI: 10.1016/j.medcle.2020.12.017

Multi-Centre, Multi-Vendor and Multi-Disease Cardiac Segmentation: The M&Ms Challenge.

PMID: 34138702
Journal: IEEE TRANSACTIONS ON MEDICAL IMAGING
Year: 2021
Reference: IEEE Trans Med Imaging. 2021 Dec;40(12):3543-3554. doi: 10.1109/TMI.2021.3090082. Epub 2021 Nov 30.
Impact factor: 10.048
Publication type: Paper in international publication
Authors: Campello, Victor M, Gkontra, Polyxeni, Izquierdo, Cristian, Martin-Isla, Carlos, Sojoudi, Alireza, Full, Peter M, Maier-Hein, Klaus, Descalzo, Martin L, Guala, Andrea, Mura, Lucia La et al.
DOI: 10.1109/TMI.2021.3090082

Clinical Impact of Crossover Techniques for Primary Access Hemostasis in Transfemoral Transcatheter Aortic Valve Replacement Procedures.

PMID: 33600353
Journal: JOURNAL OF INVASIVE CARDIOLOGY
Year: 2021
Reference: J Invasive Cardiol. 2021 Apr;33(4):E302-E311. Epub 2021 Feb 18.
Impact factor: 2.022
Publication type: Paper in international publication
Authors: Colombo, Antonio, Munoz Garcia, Erika, Vera Urquiza, Rafael, Jimenez-Quevedo, Pilar, Pascual, Isaac, Garcia Del Blanco, Bruno, Sabate, Manel, Mohammadi, Siamak, Freitas-Ferraz, Afonso B, Muntane-Carol, Guillem et al.
DOI:

Thin- versus thick-strut polymer-free biolimus-eluting stents: the BioFreedom QCA randomised trial.

PMID: 33433389
Journal: EuroIntervention
Year: 2021
Reference: EuroIntervention. 2021 Jun 25;17(3):233-239. doi: 10.4244/EIJ-D-20-01162.
Impact factor: 6.534
Publication type: Paper in international publication
Authors: Flensted Lassen, Jens, Stoll, Hans-Peter, Costa, Ricardo A, Sabate, Manel, Okkels Jensen, Lisette, Tilsted, Hans-Henrik, Moreno, Raul, Garcia Del Blanco, Bruno, Macaya, Carlos, Perez de Prado, Armando et al.
DOI: 10.4244/EIJ-D-20-01162

Speaking a common language: Introduction to a standard terminology for the bicuspid aortic valve and its aortopathy.

PMID: 32599027
Journal: PROGRESS IN CARDIOVASCULAR DISEASES
Year: 2020
Reference: Prog Cardiovasc Dis. 2020 Jul-Aug;63(4):419-424. doi: 10.1016/j.pcad.2020.06.006. Epub 2020 Jun 26.
Impact factor: 6.763
Publication type: Review in international publication
Authors: Michelena, Hector I, Corte, Alessandro Della, Evangelista, Arturo, Maleszewski, Joseph J, Enriquez-Sarano, Maurice, Bax, Jeroen J, Otto, Catherine M, Schafers, Hans-Joachim et al.
DOI: 10.1016/j.pcad.2020.06.006

Correction to: Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain.

PMID: 32600467
Journal: Health and Quality of Life Outcomes
Year: 2020
Reference: Health Qual Life Outcomes. 2020 Jun 29;18(1):205. doi: 10.1186/s12955-020-01443-8.
Impact factor: 2.344
Publication type: Letter or abstract
Authors: Francone, Marco, Napp, Adriane, Preuss, Daniel, Dreger, Henryk, Feuchtner, Gudrun, Plank, Fabian, Suchanek, Vojtech, Veselka, Josef, Engstrom, Thomas, Kofoed, Klaus F et al.
DOI: 10.1186/s12955-020-01443-8

Long-term outcomes after transcatheter aortic valve implantation in failed bioprosthetic valves.

PMID: 32592401
Journal: EUROPEAN HEART JOURNAL
Year: 2020
Reference: Eur Heart J. 2020 Aug 1;41(29):2731-2742. doi: 10.1093/eurheartj/ehaa544.
Impact factor: 22.673
Publication type: Paper in international publication
Authors: Testa, Luca, Agrifoglio, Marco, Whisenant, Brian, Sathananthan, Janarthanan, Napodano, Massimo, Landi, Antonio, Fiorina, Claudia, Zittermann, Armin, Veulemans, Verena, Sinning, Jan-Malte et al.
DOI: 10.1093/eurheartj/ehaa544

Contrast-Enhanced Echocardiographic Measurement of Left Ventricular Wall Thickness in Hypertrophic Cardiomyopathy: Comparison with Standard Echocardiography and Cardiac Magnetic Resonance.

PMID: 32564979
Journal: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
Year: 2020
Reference: J Am Soc Echocardiogr. 2020 Sep;33(9):1106-1115. doi: 10.1016/j.echo.2020.04.009. Epub 2020 Jun 18.
Impact factor: 5.508
Publication type: Paper in international publication
Authors: Gonzalez-Gonzalez, Ana Maria, Maldonado, Giuliana, Gutierrez-Garcia-Moreno, Laura, Vivancos-Delgado, Ricardo, De Mora-Martin, Manuel, Rodriguez-Palomares, Jose Fernando, Evangelista-Masip, Arturo, Urbano-Moral, Jose Angel et al.
DOI: 10.1016/j.echo.2020.04.009

Prognostic Value of Initial Left Ventricular Remodeling in Patients With Reperfused STEMI.

PMID: 31202752
Journal: JACC-Cardiovascular Imaging
Year: 2019
Reference: JACC Cardiovasc Imaging. 2019 Dec;12(12):2445-2456. doi: 10.1016/j.jcmg.2019.02.025. Epub 2019 Jun 12.
Impact factor: 10.975
Publication type: Paper in international publication
Authors: Gavara, Jose, Ferreira-Gonzalez, Ignacio, Valente, Filipa, Rios, Cesar, Rodriguez-Garcia, Julian, Bonanad, Clara, Garcia Del Blanco, Bruno, Minana, Gema, Mutuberria, Maria, Nunez, Julio et al.
DOI: 10.1016/j.jcmg.2019.02.025

High-fat diet improves tolerance to myocardial ischemia by delaying normalization of intracellular PH at reperfusion.

PMID: 31194987
Journal: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Year: 2019
Reference: J Mol Cell Cardiol. 2019 Aug;133:164-173. doi: 10.1016/j.yjmcc.2019.06.001. Epub 2019 Jun 10.
Impact factor: 5.055
Publication type: Paper in international publication
Authors: Inserte, Javier, Aluja, David, Barba, Ignasi, Ruiz-Meana, Marisol, Miro, Elisabet, Poncelas, Marcos, Vilardosa, Ursula, Castellano, Jose, Garcia-Dorado, David et al.
DOI: 10.1016/j.yjmcc.2019.06.001

Use and Outcomes of Triple Antithrombotic Therapy with Non-Vitamin K Antagonists in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention.

PMID: 31176420
Journal: AMERICAN JOURNAL OF THE MEDICAL SCIENCES
Year: 2019
Reference: Am J Med Sci. 2019 Aug;358(2):95-103. doi: 10.1016/j.amjms.2019.03.009. Epub 2019 Mar 28.
Impact factor: 1.962
Publication type: Paper in international publication
Authors: Casamira, Nuria, Garcia-Camarero, Tamara, Montoro-Ronsano, J Bruno, Veiga, Gabriela, Del Blanco, Bruno Garcia, De La Torre, Jose Maria, Gordon, Blanca, Garcia-Dorado, David, Sambola, Antonia et al.
DOI: 10.1016/j.amjms.2019.03.009

Validity of the minimum basic data set for research into outcomes in the care of acute coronary syndrome. Response.

PMID: 31175068
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Aug;72(8):697-698. doi: 10.1016/j.rec.2019.03.010. Epub 2019 Jun 5.
Impact factor: 5.078
Publication type: Letter or abstract
Authors: Bernal, Jose Luis, Barrabes, Jose A, Fernandez-Perez, Cristina, Elola, Francisco Javier et al.
DOI: 10.1016/j.rec.2019.03.010

Everolimus drug-eluting stent performance in patients with long coronary lesions: The multicenter Longprime registry.

PMID: 29774986
Journal: CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
Year: 2018
Reference: Catheter Cardiovasc Interv. 2018 Dec 1;92(7):E493-E501. doi: 10.1002/ccd.27657. Epub 2018 May 18.
Impact factor: 2.602
Publication type: Paper in international publication
Authors: Albert, Franck, Mainar Tello, Vicente, Diaz Fernandez, Jose Francisco, Camacho Freire, Santiago Jesus, Fernandez Guerrero, Juan Carlos, Delarche, Nicolas, Bretelle, Christophe, Zueco Gil, Javier, Palop, Ramon Lopez, Garcia Del Blanco, Bruno et al.
DOI: 10.1002/ccd.27657

Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease.

PMID: 29695249
Journal: JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
Year: 2018
Reference: J Cardiovasc Magn Reson. 2018 Apr 26;20(1):28. doi: 10.1186/s12968-018-0451-1.
Impact factor: 5.457
Publication type: Paper in international publication
Authors: Rodriguez-Palomares, Jose Fernando, Dux-Santoy, Lydia, Guala, Andrea, Kale, Raquel, Maldonado, Giuliana, Teixido-Tura, Gisela, Galian, Laura, Huguet, Marina, Valente, Filipa, Gutierrez, Laura et al.
DOI: 10.1186/s12968-018-0451-1

Syncope and bundle branch block : Diagnostic approach.

PMID: 29696347
Journal: Herzschrittmachertherapie & Elektrophysiologie
Year: 2018
Reference: Herzschrittmacherther Elektrophysiol. 2018 Jun;29(2):161-165. doi: 10.1007/s00399-018-0560-4. Epub 2018 Apr 25.
Impact factor: 0
Publication type: Review in international publication
Authors: Moya, Angel, Rivas-Gandara, Nuria, Perez-Rodon, Jordi, Franciso-Pascual, Jaume, Santos-Ortega, Alba, Fumero, Patricia, Roca-Luque, Ivo et al.
DOI: 10.1007/s00399-018-0560-4

Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research.

PMID: 29685932
Journal: CIRCULATION
Year: 2018
Reference: Circulation. 2018 Apr 24;137(17):1846-1860. doi: 10.1161/CIRCULATIONAHA.117.031264.
Impact factor: 18.88
Publication type: Review in national publication
Authors: Eusanio, Marco Di, Sechtem, Udo, Ehrlich, Marek P, Trimarchi, Santi, Braverman, Alan C, Myrmel, Truls, Harris, Kevin M, Hutchinson, Stuart, O'Gara, Patrick, Suzuki, Toru et al.
DOI: 10.1161/CIRCULATIONAHA.117.031264

The Image of Cardiology.

PMID: 27247986
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2016
Reference: Rev Esp Cardiol (Engl Ed). 2016 Feb;69(2):201.
Impact factor: 4.596
Publication type: Paper in international publication
Authors: Avanzas, Pablo, Ferreira, Ignacio, Sanchis, Juan, Arias, Miguel Angel, Perez-de-Isla, Leopoldo et al.
DOI: 10.1016/j.rec.2015.09.013

Neurological damage after transcatheter aortic valve implantation compared with surgical aortic valve replacement in intermediate risk patients.

PMID: 26646556
Journal: Clinical Research in Cardiology
Year: 2016
Reference: Clin Res Cardiol. 2016 Jun;105(6):508-17. doi: 10.1007/s00392-015-0946-9. Epub 2015 Dec 8.
Impact factor: 4.324
Publication type: Paper in international publication
Authors: Cascant, Purificacion, Abdul-Jawad Altisent, Omar, Ferreira-Gonzalez, Ignacio, Marsal, Josep R, Ribera, Aida, Auger, Cristina, Ortega, Gemma, Serra, Vicenc, Sureda, Carlos, Igual, Albert et al.
DOI: 10.1007/s00392-015-0946-9

Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double-blind, randomized comparison of two uptitration regimens.

PMID: 27170530
Journal: EUROPEAN JOURNAL OF HEART FAILURE
Year: 2016
Reference: Eur J Heart Fail. 2016 Sep;18(9):1193-202. doi: 10.1002/ejhf.548. Epub 2016 May 12.
Impact factor: 5.135
Publication type: Paper in international publication
Authors: Martinez-Selles, Manuel, Senni, Michele, McMurray, John J V, Wachter, Rolf, McIntyre, Hugh F, Reyes, Antonio, Majercak, Ivan, Andreka, Peter, Shehova-Yankova, Nina, Anand, Inder et al.
DOI: 10.1002/ejhf.548

Plasma B-type natriuretic peptide levels are poorly related to the occurrence of ischemia or ventricular arrhythmias during symptom-limited exercise in low-risk patients.

PMID: 27186178
Journal: Archives of Medical Science
Year: 2016
Reference: Arch Med Sci. 2016 Apr 1;12(2):341-8. doi: 10.5114/aoms.2016.59258. Epub 2016 Apr 12.
Impact factor: 1.812
Publication type: Paper in international publication
Authors: Porta, Andreu, Barrabes, Jose A, Candell-Riera, Jaume, Agullo, Luis, Aguade-Bruix, Santiago, de Leon, Gustavo, Figueras, Jaume, Garcia-Dorado, David et al.
DOI: 10.5114/aoms.2016.59258

Low-gradient Severe Aortic Stenosis With Preserved Ejection Fraction. A Pathophysiologic Entity or a Methodologic Disparity?

PMID: 26144870
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2015
Reference: Rev Esp Cardiol (Engl Ed). 2015 Aug;68(8):649-52. doi: 10.1016/j.rec.2015.04.007. Epub 2015 Jul 3.
Impact factor: 3.792
Publication type: Paper in national publication
Authors: Evangelista, Arturo, Galian, Laura et al.
DOI: 10.1016/j.rec.2015.04.007

Presentation, Diagnosis, and Outcomes of Acute Aortic Dissection: 17-Year Trends From the International Registry of Acute Aortic Dissection.

PMID: 26205591
Journal: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Year: 2015
Reference: J Am Coll Cardiol. 2015 Jul 28;66(4):350-8. doi: 10.1016/j.jacc.2015.05.029.
Impact factor: 16.503
Publication type: Paper in international publication
Authors: Pape, Linda A, Awais, Mazen, Woznicki, Elise M, Suzuki, Toru, Trimarchi, Santi, Evangelista, Arturo, Myrmel, Truls, Larsen, Magnus, Harris, Kevin M, Greason, Kevin et al.
DOI: 10.1016/j.jacc.2015.05.029

Improving the Diagnosis of Infective Endocarditis in Prosthetic Valves and Intracardiac Devices With 18F-Fluordeoxyglucose Positron Emission Tomography/Computed Tomography Angiography: Initial Results at an Infective Endocarditis Referral Center.

PMID: 26276890
Journal: CIRCULATION
Year: 2015
Reference: Circulation. 2015 Sep 22;132(12):1113-26. doi: 10.1161/CIRCULATIONAHA.115.015316. Epub 2015 Aug 14.
Impact factor: 14.43
Publication type: Paper in international publication
Authors: Galinanes, Manuel, Maisterra-Santos, Olga, Garcia-Dorado, David, Castell-Conesa, Joan, Almirante, Benito, Aguade-Bruix, Santiago, Tornos, Pilar, Rodriguez-Palomares, Jose, Gonzalez, Juan J, Oristrell, Gerard et al.
DOI: 10.1161/CIRCULATIONAHA.115.015316

Echocardiography in the Assessment of Left Atrial Pressure After Pediatric Heart Surgery: A Comparison Study With Measurements Obtained From Left Atrial Catheter.

PMID: 26180162
Journal: World Journal of Pediatrics
Year: 2015
Reference: World J Pediatr Congenit Heart Surg. 2015 Jul;6(3):438-42. doi: 10.1177/2150135115589999.
Impact factor: 1.236
Publication type: Paper in international publication
Authors: Roses, Ferran, Figueras-Coll, Marc, Sanchez-de-Toledo, Joan, Gran, Ferran, Abella, Raul, Perez-Hoyos, Santiago et al.
DOI: 10.1177/2150135115589999

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The consensus document is the result of multidisciplinary work that takes into account the risks associated with all stages of women's lives and the differences compared to men.

The study, which involved Vall d'Hebron, developed an action plan to efficiently allocate resources to patients most at risk of suffering this complication.

In light of this evidence, hospitals such as Vall d'Hebron have already started to include warnings about environmental pollution in their hospital discharge plans after a myocardial infarction.