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Hepato-bilio-pancreatic surgery (HBP) and liver transplantation

Until 2017, this group was constituted as a consolidated group in the VHIR under the name of "Digestive Transplants" with a consolidated research trajectory. Our group has two large areas of research: liver transplantation, which is cross-sectional adult-pediatric and; on the other hand, research, specifically in the fields of liver resections, liver cancer (primary or metastatic), biliary cancer, pancreatic cancer and pancreatitis. Both areas have very innovative aspects, with translational objectives, including artificial intelligence, transcriptomics and molecular biology.

The general objective of the liver transplant research area is to improve the preservation of liver grafts, as well as increase the survival of grafts and transplant patients. The research area related to cancer or acute pancreatitis has as a general objective to improve the management and treatment of patients with pancreatitis, as well as to improve the diagnosis and survival of cancer patients.

Team

Cristina Dopazo Taboada

Cristina Dopazo Taboada

Main researcher
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
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Itxarone Izaskun Bilbao Aguirre

Itxarone Izaskun Bilbao Aguirre

Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
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Joaquin Balsells Valls

Joaquin Balsells Valls

Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
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Laia Blanco Cuso

Laia Blanco Cuso

Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
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Cristina Padros Fornieles

Cristina Padros Fornieles

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
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Elizabeth Pando Rau

Elizabeth Pando Rau

Main researcher
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Cristina Dopazo Taboada

Cristina Dopazo Taboada

Main researcher
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Itxarone Izaskun Bilbao Aguirre

Itxarone Izaskun Bilbao Aguirre

Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Joaquin Balsells Valls

Joaquin Balsells Valls

Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Laia Blanco Cuso

Laia Blanco Cuso

Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Cristina Padros Fornieles

Cristina Padros Fornieles

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Elizabeth Pando Rau

Elizabeth Pando Rau

Main researcher
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more

Research lines

Avaluació preoperatòria de la funció hepàtica amb sistemes sense contrast multi paramètric (MR o LiverMultiScan)

L'objectiu de minimitzar el risc de insuficiència hepàtica post-resecció.

IP: Ernest Hidalgo Llompart, Mireia Caralt Barba

Cirurgia mínimament invasiva per pacients amb hipertensió portal i hepatocarcinoma

Projecte que avalua la cirurgia mínimament invasiva en la resecció de tumors en pacients amb hipertensió portal clínicament significativa.

IP: Ramon Charco Torra, Concepción Gomez Gavara

Factors de risc i perfils genètics de recurrència en càncer de pàncreas

IP: Elizabeth Pando Rau, Joaquin Balsells Valls

Hipertensió portal esquerra segmentaria secundaria a neoplàsia localment avançada

En col·laboració con grup CIBEREHD-Dra. Macarena Simon.

IP: Elizabeth Pando Rau, Joaquin Balsells Valls

Projects

TACTIC: Explorando soluciones a los retos de salud mediante ciencia disruptiva, terapias avanzadas y medicina de sistemas

IP: Begoña Benito Villabriga
Collaborators: Carmen Escudero Iriarte, Laia Ventura i Expósito, Susana Otero Romero, Ibane Abasolo Olaortua, Ignacio Ferreira González, José Antonio Barrabés Riu, Carlos Nos Llopis, Pablo Velasco Puyó, Jose Fernando Rodríguez Palomares, María Rosario Pérez- Torres Lobato, Sunny Malhotra Sareen, Belen Perez Dueñas, Jaume Sastre Garriga, Joan López Hellin, Antonia Sambola Ayala, Jordi Rio Izquierdo, Nuria Rivas Gandara, Jordi Perez Rodon, Aroa Soriano Fernández, Manuel Comabella Lopez, Antonio Rodríguez Sinovas, Gisela Teixido Tura, Antonia Pijuan Domenech, Roser Ferrer Costa, Joaquin Seras Franzoso, Carmen Tur Gomez, Maria Cristina Díaz de Heredia Rubio, Laia Yañez Bisbe, Julia German Cortes, Maria Jose Pérez García, Miguel Segura Ginard, Diego Baranda Martínez-Abasca, Cristina Auger Acosta, Neus Bellera Gotarda, Herena Eixarch Ahufinger, M Mar Mañu Pereira, Deborah Pareto Onghena, Lorena Valero Arrese, Aitor Uribarri Gonzalez, Jordi Bañeras Rius, Alex Rovira Cañellas, Mar Tintore Subirana, Bruno García del Blanco, Maria Teresa Salcedo Allende, Marisol Ruiz Meana, Ana Belén Méndez Fernández, Xavier Montalban Gairín, Simon Schwartz Navarro, Anna Llort Sales, Carmen Espejo Ruiz, Raquel Hladun Alvaro, Angels Alcina Mila, Sandra Mancilla Zamora, Zamira Vanessa Diaz Riascos, Ana Zabalza de Torres, Marc Miquel Moltó Abad, Javier Inserte Igual, Luciana Midaglia Fernandez, Elizabeth Pando Rau, Gabriela Guillén Burrieza, Ana Laura Cazurro Gutierrez, David Gómez Andrés, Alvaro Cobo Calvo, Alvaro Calabuig Goena, Joaquin Castillo Justribo, Lydia Dux-Santoy Hurtado, Lucas Moreno Martín-Retortillo, Andres Miguez Gonzalez, Josep Roma Castanyer, Laura Dos Subirá, Nicolás Miguel Fissolo, Maria Nazarena Pizzi, Tian Tian, Fernanda Raquel Da Silva Andrade, Diana Fernandes de Rafael, Andrea Guala
Funding agency: Instituto de Salud Carlos III
Funding: 2494527.53
Reference: FORT23/00034
Duration: 01/01/2024 - 31/12/2027

PANCREATIA: un algoritmo de predicción de la gravedad de la pancreatitis aguda utilizando machine learning.

IP: Elizabeth Pando Rau
Collaborators: Laia Blanco Cuso, Nair Sonia Fernandes Montes
Funding agency: Instituto de Salud Carlos III
Funding: 65000
Reference: PI23/01890
Duration: 01/01/2024 - 31/12/2026

New tool based on Artificial Intelligence and Biomarkers for early non-invasive diagnosis of Pancreatic Cancer - AI-Early PanC

IP: -
Collaborators: Santiago Pérez Hoyos, Joaquin Balsells Valls, Joan Dot Bach
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 293321
Reference: CPP2022- 009592
Duration: 01/10/2023 - 30/09/2026

Ministerio de Ciencia

Estudio sobre fertilidad y embarazo tras cirugia por enfermedades enflamatorias intestinales

IP: Joaquin Balsells Valls
Collaborators: Gianluca Pellino
Funding agency: Asociación Española de Cirujanos
Funding: 5000
Reference: AEC/BECA/2022/IBD/FERTILITY
Duration: 18/10/2022 - 19/10/2025

Publications

Intraductal papillary neoplasms of the bile duct: A European retrospective multicenter observational study (EUR-IPNB Study).

PMID: 36917142
Journal: International Journal of Surgery
Year: 2023
Reference: Int J Surg. 2023 Mar 15. doi: 10.1097/JS9.0000000000000280.
Impact factor:
Publication type: Paper in international publication
Authors: Achalandabaso, Mar; Achalandabaso, Mar; Alcazar-Lopez, Candido F; Alsammani, Mohammedsuror; Amaral, Maria Joao; Andersson, Bodil; Asbun, Horacio; Balakrishnan, Anita; Berrevoet, Frederik; Bjornsson, Bergthor et al.
DOI: 10.1097/JS9.0000000000000280

Impact of comorbidities on hospital mortality in patients with acute pancreatitis: a population-based study of 110,021 patients.

PMID: 36949385
Journal: BMC GASTROENTEROLOGY
Year: 2023
Reference: BMC Gastroenterol. 2023 Mar 23;23(1):81. doi: 10.1186/s12876-023-02730-6.
Impact factor:
Publication type: Paper in international publication
Authors: Balsells, Joaquim; Barros, Marta; Blanco, Laia; Charco, Ramon; Fernandes, Nair; Herms, Daniel; Hidalgo, Nils Jimmy; Mata, Rodrigo; Pando, Elizabeth; Villasante, Sara et al.
DOI: 10.1186/s12876-023-02730-6

Impact of Prophylactic Norfloxacin in Multidrug Resistant Bacterial Infections in the Early Liver Posttransplant Period.

PMID: 36987799
Journal: Experimental and Clinical Transplantation
Year: 2023
Reference: Exp Clin Transplant. 2023 Mar;21(3):236-244. doi: 10.6002/ect.2022.0412.
Impact factor:
Publication type: Paper in international publication
Authors: Castells, Lluis; Dopazo, Cristina; Len, Oscar; Llado, Laura; Los-Arcos, Ibai; Lung, Mayli; Nuvials, Xavier; Oriol, Isabel; Perez-Cameo, Cristina; Sabe, Nuria et al.
DOI: 10.6002/ect.2022.0412

Use and outcome of minimally invasive pancreatic surgery in the European E-MIPS registry.

PMID: 37028826
Journal: HPB
Year: 2023
Reference: HPB (Oxford). 2023 Apr;25(4):400-408. doi: 10.1016/j.hpb.2022.07.015. Epub 2022 Aug 17.
Impact factor:
Publication type: Paper in international publication
Authors: Abu Hilal, Mohammed; Balsells, Joaquim; Berrevoet, Frederik; Besselink, Marc G; Bjornsson, Bergthor; Boggi, Ugo; Bratlie, Svein O; Burdio, Fernando; Cabus, Santiago S; Can, Mehmet F et al.
DOI: 10.1016/j.hpb.2022.07.015

Thesis

Graft preservation and ischemia reperfusion injury in liver trasnplantation. Studies in immunomodulation and attenuation of injury

PhD student: Juan Andres Echeverri Cifuentes
Director/s: Ramon Charco Torra, Gonzalo Sapisochin Cantis
University:
Year: 2021

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

The study also linked improved microbiota diversity to better liver function.

Over the course of two days, experts presented the latest advances in vectors, different gene modification techniques and their transfer to clinical practice.