About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our main scientific interest is to understand, from a multidisciplinary and translational approach, the molecular and cellular processes leading to renal dysfunction in several kidney pathologies. Specifically, our research lines are
We are experts on the following areas:
To sum up, our research main objective is to combine –omic data from cellular and animal models with patients’ data to identify novel biomarkers and possible treatments for several renal diseases.
PMID: 37885338 Journal: KAOHSIUNG JOURNAL OF MEDICAL SCIENCES Year: 2023 Reference: Kaohsiung J Med Sci. 2023 Oct 27. doi: 10.1002/kjm2.12771. Impact factor: Publication type: Paper in international publication Authors: Abe, Hiroshi; Ahn, Sang Bong; Algaba, Ferran; An, Jihyun; Arai, Taeang; Atsukawa, Masanori; Buti, Maria; Cheung, Ka Shing; Cho, Yong Kyun; Chuang, Wan-Long et al. DOI: 10.1002/kjm2.12771
PMID: 37951467 Journal: Cirugia espanola Year: 2023 Reference: Cir Esp (Engl Ed). 2023 Nov 9:S2173-5077(23)00194-1. doi: 10.1016/j.cireng.2023.02.013. Impact factor: Publication type: Paper in international publication Authors: Areny, A; Areny, A; Arevalo, J; Campoy, I; Cantero-Recasens, G; Duran, M; Duran, M; Hernandez Granados, Pilar; Lopez-Cano, Manuel; Martinez, C et al. DOI: 10.1016/j.cireng.2023.02.013
PMID: 35485759 Journal: Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica Year: 2022 Reference: Cir Pediatr. 2022 Apr 1;35(2):94-98. doi: 10.54847/cp.2022.02.19. Impact factor: Publication type: Letter or abstract Authors: Ariceta, G; Asensio, M; Coma, A; Cruz, A; Gander, R; Lopez, M; Molino, J A; Munoz, M; Rios, H; Royo, G F et al. DOI: 10.54847/cp.2022.02.19
PMID: 35483523 Journal: KIDNEY INTERNATIONAL Year: 2022 Reference: Kidney Int. 2022 Sep;102(3):592-603. doi: 10.1016/j.kint.2022.02.040. Epub 2022 Apr 26. Impact factor: Publication type: Paper in international publication Authors: Anarat, Ali; Ariceta, Gema; Aurelle, Manon; Baiko, Sergey; Balasz-Chmielewska, Irena; Benetti, Elisa; Benz, Marcus R; Bjerre, Anna; Boyer, Olivia; Deng, Fang et al. DOI: 10.1016/j.kint.2022.02.040
PMID: 35406673 Journal: Cells Year: 2022 Reference: Cells. 2022 Mar 25;11(7). pii: cells11071109. doi: 10.3390/cells11071109. Impact factor: Publication type: Review in international publication Authors: Ariceta, Gema; Elenberg, Ewa; Hohenfellner, Katharina; Nesterova, Galina; Soliman, Neveen A; Topaloglu, Rezan et al. DOI: 10.3390/cells11071109
PMID: 35366849 Journal: BMC CANCER Year: 2022 Reference: BMC Cancer. 2022 Apr 2;22(1):357. doi: 10.1186/s12885-022-09355-0. Impact factor: Publication type: Review in international publication Authors: Celma, Ana; Cuadras, Merce; de Torres, Ines M; Morote, Juan; Planas, Jacques; Regis, Lucas; Semidey, M Eugenia; Trilla, Enrique et al. DOI: 10.1186/s12885-022-09355-0
PMID: 33912759 Journal: Kidney International Reports Year: 2021 Reference: Kidney Int Rep. 2021 Feb 3;6(4):1088-1098. doi: 10.1016/j.ekir.2021.01.029. eCollection 2021 Apr. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Barrios, Kelly; Brown, Bob D; Hoppe, Bernd; Langman, Craig B; Rosskamp, Ralf et al. DOI: 10.1016/j.ekir.2021.01.029
PMID: 33359150 Journal: AMERICAN JOURNAL OF KIDNEY DISEASES Year: 2021 Reference: Am J Kidney Dis. 2021 May;77(5):684-695.e1. doi: 10.1053/j.ajkd.2020.11.011. Epub 2020 Dec 22. Impact factor: Publication type: Paper in international publication Authors: Allende, Natalia; Alonso, Marina; Ariceta, Gema; Avila, Ana; Barros, Xoana; Bravo, Luis; Cabello, Virginia; Calvo, Consuelo; Caravaca, Francisco; Caravaca-Fontan, Fernando et al. DOI: 10.1053/j.ajkd.2020.11.011
PMID: 33892867 Journal: KIDNEY INTERNATIONAL Year: 2021 Reference: Kidney Int. 2021 May;99(5):1244. doi: 10.1016/j.kint.2021.03.008. Impact factor: Publication type: Letter or abstract Authors: Antognoli, Guilia; Arepally, Gowthami; Ariceta, Gema; Babu, Sunil; Barbour, Tom; Blasco, Miquel; Boyer-Suavet, Sonia; Broeders, Nilufer; Brown, Fiona; Campbell, Philip et al. DOI: 10.1016/j.kint.2021.03.008
PMID: 33881640 Journal: PEDIATRIC NEPHROLOGY Year: 2021 Reference: Pediatr Nephrol. 2021 Oct;36(10):3133-3142. doi: 10.1007/s00467-021-05066-z. Epub 2021 Apr 21. Impact factor: Publication type: Paper in international publication Authors: Aguirre, Mireia; Ariceta, Gema; Castano, Luis; Dall'Anese, Cecilia; Garcia-Castano, Alejandro; Garcia-Ledesma, Paula; Garcia-Perez, Nelida; Gomez-Conde, Sara; Gondra, Leire; Herrero, Maria et al. DOI: 10.1007/s00467-021-05066-z
PMID: 31722796 Journal: NEFROLOGIA Year: 2020 Reference: Nefrologia. 2020 Mar - Apr;40(2):142-151. doi: 10.1016/j.nefro.2019.07.002. Epub 2019 Nov 10. Impact factor: Publication type: Paper in national publication Authors: Ariceta, Gema; Buj, Maria Jose; Furlano, Monica; Martinez, Victor; Matamala, Anna; Morales, Montserrat; Robles, Nicolas Roberto; Sans, Laia; Torra, Roser; Villacampa, Felipe et al. DOI: 10.1016/j.nefro.2019.07.002
PMID: 32067845 Journal: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS Year: 2020 Reference: Urol Oncol. 2020 May;38(5):410-417. doi: 10.1016/j.urolonc.2019.12.013. Epub 2020 Feb 15. Impact factor: Publication type: Paper in international publication Authors: Celma, Anna; de Torres, Ines M; Diaz, Fernando; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Roche, Sarai; Semedey, Maria E; Trilla, Enrique et al. DOI: 10.1016/j.urolonc.2019.12.013
PMID: 31980684 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Jan 24;10(1):1159. doi: 10.1038/s41598-020-58197-y. Impact factor: Publication type: Paper in international publication Authors: Helm, Dominic; Jacobs-Cacha, Conxita; Lopez-Hellin, Joan; Meseguer, Anna; Moreso, Francesc J; Puig-Gay, Natalia; Rettel, Mandy; Savitski, Mikhail M; Sellares, Joana; Seron, Daniel et al. DOI: 10.1038/s41598-020-58197-y
PMID: 31641778 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2020 Reference: Nephrol Dial Transplant. 2020 Jan 1;35(1):47-64. doi: 10.1093/ndt/gfz159. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Bacchetta, Justine; Bakkaloglu, Sevcan A; Groothoff, Jaap; Haffner, Dieter; Schmitt, Claus Peter; Shroff, Rukshana; Vervloet, Marc; Wan, Mandy et al. DOI: 10.1093/ndt/gfz159
PMID: 30374605 Journal: PEDIATRIC NEPHROLOGY Year: 2019 Reference: Pediatr Nephrol. 2019 Apr;34(4):649-655. doi: 10.1007/s00467-018-4122-0. Epub 2018 Oct 29. Impact factor: Publication type: Paper in international publication Authors: Alpay, Harika; Ariceta, Gema; Aufricht, Christoph; Bacchetta, Justine; Bakkaloglu, Sevcan; Bayazit, Aysun; Caliskan, Salim; Conti, Valerie Said; do Sameiro Faria, Maria; Dufek, Stephanie et al. DOI: 10.1007/s00467-018-4122-0
PMID: 29260317 Journal: PEDIATRIC NEPHROLOGY Year: 2019 Reference: Pediatr Nephrol. 2019 Apr;34(4):571-578. doi: 10.1007/s00467-017-3856-4. Epub 2017 Dec 19. Impact factor: Publication type: Review in national publication Authors: Ariceta, Gema; Giordano, Vincenzo; Santos, Fernando et al. DOI: 10.1007/s00467-017-3856-4
PMID: 30773598 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2019 Reference: Nephrol Dial Transplant. 2019 Jun 1;34(6):981-991. doi: 10.1093/ndt/gfy409. Impact factor: Publication type: Paper in international publication Authors: Agbas, Ayse; Ariceta, Gema; Basu, Biswanath; Belkevich, Anna; Bertholet-Thomas, Aurelia; Blanchard, Anne; Bockenhauer, Detlef; Boyer, Olivia; Burgmaier, Kathrin; Caruso, Maria Rosa et al. DOI: 10.1093/ndt/gfy409
PMID: 30407919 Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY Year: 2019 Reference: Eur J Endocrinol. 2019 Jan 1;180(1):59-70. doi: 10.1530/EJE-18-0129. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Castano, Luis; Garcia, Alejandro; Gaztambide, Sonia; Group, Renaltube; Group, Spanish Endocrinology; Madariaga, Leire; Perez de Nanclares, Gustavo et al. DOI: 10.1530/EJE-18-0129
PMID: 29396473 Journal: Scientific Reports Year: 2018 Reference: Sci Rep. 2018 Feb 2;8(1):2255. doi: 10.1038/s41598-018-20540-9. Impact factor: Publication type: Paper in international publication Authors: Alonso-Cotoner, Carmen; Azpiroz, Fernando; Fortea, Marina; Gonzalez-Castro, Ana Maria; Guagnozzi, Danila; Iribarren, Cristina; Lobo, Beatriz; Martinez, Cristina; Nieto, Adoracion; Pardo-Camacho, Cristina et al. DOI: 10.1038/s41598-018-20540-9
PMID: 28842757 Journal: PEDIATRIC NEPHROLOGY Year: 2018 Reference: Pediatr Nephrol. 2018 Feb;33(2):351-358. doi: 10.1007/s00467-017-3782-5. Epub 2017 Aug 25. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Asensio, Marino; Bilbao, Itxarone; Charco, Ramon; Juamperez, Javier; Molino, Jose A; Munoz, Marina; Quintero Bernabeu, Jesus; Rodrigo, Carlos; Rodriguez, Olalla et al. DOI: 10.1007/s00467-017-3782-5
PMID: 29307792 Journal: European Journal of Medical Genetics Year: 2018 Reference: Eur J Med Genet. 2018 May;61(5):269-272. doi: 10.1016/j.ejmg.2018.01.001. Epub 2018 Jan 4. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Fernandez-Alvarez, Paula; Garcia-Arumi, Elena; Plaja, Alberto; Sabate-Rotes, Anna; Tizzano, Eduardo; Valenzuela, Irene; Vendrell, Teresa et al. DOI: 10.1016/j.ejmg.2018.01.001
PMID: 28411971 Journal: Year: 2018 Reference: Nefrologia (Engl Ed). 2018 Mar-Apr;38(2):207-212. doi: 10.1016/j.nefro.2017.02.007. Epub 2017 Apr 12. Impact factor: Publication type: Paper in international publication Authors: Arias-Cabrales, Carlos; Burballa, Carla; Cecchini, Lluis; Crespo, Marta; Frances, Albert; Fumado, Lluis; Mir, Marisa; Pascual, Julio; Perez-Saez, Maria Jose; Redondo-Pachon, Dolores et al. DOI: 10.1016/j.nefro.2017.02.007
The communication is part of a study aimed at identifying the mechanisms of progression of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis, a rare disease that affects the kidneys.
"Patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis present miRNA profiles in urinary extracellular vesicles associated with disease progression" was the awarded work.
Researchers at the VHIR have carried out a study showing that the ClC-5 protein regulates collagen levels through the β-catenin pathway and lysosomal degradation.
