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Liver Diseases

The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.

Publications

[Not Available].

PMID: 38075162
Journal: Advances in Laboratory Medicine
Year: 2023
Reference: Adv Lab Med. 2023 Sep 8;4(3):205-206. doi: 10.1515/almed-2023-0113. eCollection 2023 Sep.
Impact factor:
Publication type: Editorial in national publication
Authors: Arribas, Ignacio; Augustin, Salvador; Fernandez-Calle, Pilar; Ferrer-Costa, Roser; Ferrer-Costa, Roser; Gabriel-Medina, Pablo; Gonzalez, Alvaro; Guerrero, Rafael A; Jimenez, Wladimiro; Jimenez-Masip, Alba et al.
DOI: 10.1515/almed-2023-0113

The role of HBIG in real life for patients undergoing liver transplantation due to HDV-related cirrhosis.

PMID: 38100141
Journal: LIVER INTERNATIONAL
Year: 2023
Reference: Liver Int. 2023 Dec 15. doi: 10.1111/liv.15777.
Impact factor:
Publication type: Paper in international publication
Authors: Abd Kahar, Nurul Nadhirah; Abdelrahim, Ahmed; Ahmed, Hassan; Akter, Nasreen; Al-Sarrieh, Bilal; Alfarah, Jameel; Alghazawi, Laith; Alhaboob, Nassir; Aroori, Somaiah; Arshad, Ali et al.
DOI: 10.1111/liv.15777

Shotgun metagenomics reveals interkingdom association between intestinal bacteria and fungi involving competition for nutrients.

PMID: 38098063
Journal: Microbiome
Year: 2023
Reference: Microbiome. 2023 Dec 14;11(1):275. doi: 10.1186/s40168-023-01693-w.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Canalda-Baltrons, Aleix; Card-Gowers, Joshua; d'Enfert, Christophe; Graff, Hannah; Guzek, John; Jepsen, Peter; Lazarus, Jeffrey V; Manichanh, Chaysavanh; Martin, Alexander et al.
DOI: 10.1186/s40168-023-01693-w

Phase II trial of afatinib in patients with advanced urothelial carcinoma with genetic alterations in ERBB1-3 (LUX-Bladder 1).

PMID: 38102226
Journal: BRITISH JOURNAL OF CANCER
Year: 2023
Reference: Br J Cancer. 2023 Dec 15. doi: 10.1038/s41416-023-02513-6.
Impact factor:
Publication type: Paper in international publication
Authors: Aldecoa, Iban; Araujo, Silvia G; Buti, Maria; Castellano, Daniel; Climent, Miguel A; Fernandez, Emma; Fernandez, Pedro L; Font, Albert; Forns, Xavier; Gibson, Neil et al.
DOI: 10.1038/s41416-023-02513-6

HCC risk stratification after cure of hepatitis C in patients with compensated advanced chronic liver disease.

PMID: 34871626
Journal: JOURNAL OF HEPATOLOGY
Year: 2022
Reference: J Hepatol. 2022 Apr;76(4):812-821. doi: 10.1016/j.jhep.2021.11.025. Epub 2021 Dec 3.
Impact factor:
Publication type: Paper in international publication
Authors: Ahumada, Adriana; Alonso Lopez, Sonia; Banares, Rafael; Bauer, David; Chromy, David; Ferenci, Peter; Genesca, Joan; Greenfield, Helena; Gschwantler, Michael; Hametner-Schreil, Stefanie et al.
DOI: 10.1016/j.jhep.2021.11.025

Targeted long-read sequencing reveals clonally expanded HBV-associated chromosomal translocations in patients with chronic hepatitis B.

PMID: 35295767
Journal: JHEP Reports
Year: 2022
Reference: JHEP Rep. 2022 Feb 12;4(4):100449. doi: 10.1016/j.jhepr.2022.100449. eCollection 2022 Apr.
Impact factor:
Publication type: Paper in international publication
Authors: Bhardwaj, Neeru; Bui, Nam; Buti, Maria; Chan, Henry L Y; Feierbach, Becket; Gaggar, Anuj; Han, Dong; Li, Li; Marcellin, Patrick; Martin, Ross et al.
DOI: 10.1016/j.jhepr.2022.100449

PREDICTION OF SUSTAINED RESPONSE AFTER NUCLEO(S)TIDE ANALOGUE CESSATION USING HBSAG AND HBCRAG LEVELS - A MULTICENTER STUDY (CREATE).

PMID: 33309804
Journal: Clinical Gastroenterology and Hepatology
Year: 2022
Reference: Clin Gastroenterol Hepatol. 2022 Apr;20(4):e784-e793. doi: 10.1016/j.cgh.2020.12.005. Epub 2020 Dec 10.
Impact factor:
Publication type: Paper in international publication
Authors: Agarwal, K; Ahn, S H; Berg, T; Boonstra, A; Buti, M; Carey, I; Cornberg, M; Dalekos, G N; Erler, N S; Honer Zu Siederdissen, C et al.
DOI: 10.1016/j.cgh.2020.12.005

How to interpret viral markers in the management of chronic hepatitis B infection.

PMID: 34768018
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2022
Reference: Clin Microbiol Infect. 2022 Mar;28(3):355-361. doi: 10.1016/j.cmi.2021.10.020. Epub 2021 Nov 9.
Impact factor:
Publication type: Review in international publication
Authors: Buti, Maria; Pericas, Juan M; Riveiro-Barciela, Mar et al.
DOI: 10.1016/j.cmi.2021.10.020

Assessing the impact of COVID-19 on liver cancer management (CERO-19).

PMID: 33644725
Journal: JHEP Reports
Year: 2021
Reference: JHEP Rep. 2021 Jun;3(3):100260. doi: 10.1016/j.jhepr.2021.100260. Epub 2021 Feb 23.
Impact factor:
Publication type: Paper in international publication
Authors: Acevedo, Juan; Alqahtani, Saleh A; Alvares-da-Silva, Mario Reis; Anders, Maria Margarita; Argemi, Josepmaria; Arraez, Dalia Morales; Bandi, Juan C; Basu, Bristi; Benitez, Carlos; Blaise, Lorraine et al.
DOI: 10.1016/j.jhepr.2021.100260

Secondary syphilis with liver involvement in a liver transplant recipient.

PMID: 32738832
Journal: Transplant Infectious Disease
Year: 2021
Reference: Transpl Infect Dis. 2021 Feb;23(1):e13431. doi: 10.1111/tid.13431. Epub 2020 Aug 16.
Impact factor:
Publication type: Review in international publication
Authors: Castells, Lluis; Ferrandiz-Pulido, Carla; Ferrer, Berta; Len, Oscar; Salcedo, Maria Teresa; Velasco, Marta et al.
DOI: 10.1111/tid.13431

Long-term efficacy and safety of nucleos(t)ides analogues in patients with chronic hepatitis B.

PMID: 33614029
Journal: Therapeutic advances in infectious disease
Year: 2021
Reference: Ther Adv Infect Dis. 2021 Feb 5;8:2049936120985954. doi: 10.1177/2049936120985954. eCollection 2021 Jan-Dec.
Impact factor:
Publication type: Review in international publication
Authors: Buti, Maria; Esteban, Rafael; Riveiro-Barciela, Mar; Roade, Luisa et al.
DOI: 10.1177/2049936120985954

Sophisticated viral quasispecies with a genotype-related pattern of mutations in the hepatitis B X gene of HBeAg-ve chronically infected patients.

PMID: 33603102
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Feb 18;11(1):4215. doi: 10.1038/s41598-021-83762-4.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Carioti, Luca; Casillas, Rosario; Cortese, Maria Francesca; Esteban-Mur, Rafael; Garcia-Garcia, Selene; Godoy, Cristina; Gonzalez, Carolina; Gregori, Josep; Guerrero-Murillo, Mercedes et al.
DOI: 10.1038/s41598-021-83762-4

Nursing care of patients with cirrhosis.

PMID: 31944340
Journal: HEPATOLOGY
Year: 2020
Reference: Hepatology. 2020 Mar;71(3):1106-1116. doi: 10.1002/hep.31117.
Impact factor:
Publication type: Review in international publication
Authors: Aban, Marites; Abraldes, Juan G; Alessandria, Carlo; Angeli, Paolo; Beuers, Ulrich; Caraceni, Paolo; Carol, Marta; Cervera, Marta; Chiappa, Maria Teresa; Dols, Lacey L et al.
DOI: 10.1002/hep.31117

Lowering Portal Pressure Improves Outcomes of Patients With Cirrhosis, With or Without Ascites: A Meta-Analysis.

PMID: 31176013
Journal: Clinical Gastroenterology and Hepatology
Year: 2020
Reference: Clin Gastroenterol Hepatol. 2020 Feb;18(2):313-327.e6. doi: 10.1016/j.cgh.2019.05.050. Epub 2019 Jun 5.
Impact factor:
Publication type: Paper in international publication
Authors: Abraldes, J G; Albillos, A; Alvarado, E; Augustin, S; Banares, R; Bosch, J; Bureau, C; Garcia-Pagan, J C; Garcia-Tsao, G; Genesca, J et al.
DOI: 10.1016/j.cgh.2019.05.050

Principles for implementing a population screening strategy for hepatitis C in Spain.

PMID: 31880160
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2020
Reference: Rev Esp Enferm Dig. 2020 Jan;112(1):64-70. doi: 10.17235/reed.2019.6768/2019.
Impact factor:
Publication type: Paper in international publication
Authors: Blasco, Antonio Javier; Buti, Maria; Cabezas, Joaquin; Calleja Panero, Jose Luis; Crespo, Javier; Garcia, Federico; Lazaro de Mercado, Pablo; Molero Garcia, Jose Maria et al.
DOI: 10.17235/reed.2019.6768/2019

Corrigendum to 'Alfapump(R) system vs. large volume paracentesis for refractory ascites: A multicenter randomized controlled study' [J Hepatol 67 (2017) 940-949].

PMID: 31928862
Journal: JOURNAL OF HEPATOLOGY
Year: 2020
Reference: J Hepatol. 2020 Mar;72(3):595-596. doi: 10.1016/j.jhep.2019.11.023. Epub 2020 Jan 9.
Impact factor:
Publication type: Letter or abstract
Authors: Adebayo, Danielle; Angeli, Paolo; Borisenko, Oleg; Bureau, Christophe; Chalret de Rieu, Mael; Cordoba, Juan; Elkrief, Laure; Inhaber, Neil; Jalan, Rajiv; MacDonald, Stewart et al.
DOI: 10.1016/j.jhep.2019.11.023

Epidemiological trends of HIV-1 infection in blood donors from Catalonia, Spain (2005-2014).

PMID: 28681400
Journal: TRANSFUSION
Year: 2017
Reference: Transfusion. 2017 Sep;57(9):2164-2173. doi: 10.1111/trf.14195. Epub 2017 Jul 5.
Impact factor: 3.386
Publication type: Paper in international publication
Authors: Bes, Marta, Piron, Maria, Casamitjana, Natalia, Gregori, Josep, Esteban, Juan Ignacio, Ribera, Esteban, Quer, Josep, Puig, Lluis, Sauleda, Silvia et al.
DOI: 10.1111/trf.14195

Efficacy and safety of daclatasvir-based antiviral therapy in HCV recurrence after liver transplantation. Role of cirrhosis and genotype 3. A multi-centre cohort study.

PMID: 28608619
Journal: TRANSPLANT INTERNATIONAL
Year: 2017
Reference: Transpl Int. 2017 Oct;30(10):1041-1050. doi: 10.1111/tri.12999. Epub 2017 Jul 27.
Impact factor: 3.079
Publication type: Paper in international publication
Authors: Testillano, Milagros, Salcedo, Magdalena, Prieto, Martin, Castells, Lluis, Pascasio, Juan Manuel, Alvarez, Jose Luis Montero, Fernandez, Inmaculada, Sanchez-Antolin, Gloria, Gonzalez-Dieguez, Luisa, Garcia-Gonzalez, Miguel et al.
DOI: 10.1111/tri.12999

Spanish Registry of Patients With Alpha-1 Antitrypsin Deficiency: Database Evaluation and Population Analysis.

PMID: 27323654
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2017
Reference: Arch Bronconeumol. 2017 Jan;53(1):13-18. doi: 10.1016/j.arbres.2016.05.003. Epub 2016 Jun 17.
Impact factor: 2.979
Publication type: Paper in national publication
Authors: Blanco, Ignacio, Martinez, Maria Teresa, Rodriguez, Esther, Bustamante, Ana, Casas, Francisco, Cadenas, Sergio, Hernandez, Jose M, Lazaro, Lourdes, Torres, Maria, Curi, Sergio et al.
DOI: 10.1016/j.arbres.2016.05.003

Interferon-Free Therapy in Elderly Patients With Advanced Liver Disease.

PMID: 28585554
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2017
Reference: Am J Gastroenterol. 2017 Sep;112(9):1400-1409. doi: 10.1038/ajg.2017.157. Epub 2017 Jun 6.
Impact factor: 9.566
Publication type: Paper in international publication
Authors: Roget, Merce, Lens, Sabela, Fernandez, Inmaculada, Rodriguez-Tajes, Sergio, Hontangas, Vanessa, Vergara, Mercedes, Forne, Montserrat, Calleja, Jose Luis, Diago, Moises, Llaneras, Jordi et al.
DOI: 10.1038/ajg.2017.157

Blog

News

The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.

On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.

Estudi sobre els patrons de consum habitual de l'alcohol en població jove

Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.

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