About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 38102226 Journal: BRITISH JOURNAL OF CANCER Year: 2023 Reference: Br J Cancer. 2023 Dec 15. doi: 10.1038/s41416-023-02513-6. Impact factor: Publication type: Paper in international publication Authors: Aldecoa, Iban; Araujo, Silvia G; Buti, Maria; Castellano, Daniel; Climent, Miguel A; Fernandez, Emma; Fernandez, Pedro L; Font, Albert; Forns, Xavier; Gibson, Neil et al. DOI: 10.1038/s41416-023-02513-6
PMID: 38111084 Journal: LIVER INTERNATIONAL Year: 2023 Reference: Liver Int. 2023 Dec 18. doi: 10.1111/liv.15814. Impact factor: Publication type: Paper in international publication Authors: Barreira-Diaz, Ana; Buti, Maria; Esteban, Rafael; Feliu-Prius, Anna; Palom, Adriana; Rando, Ariadna; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Ruiz-Cobo, Juan C; Vargas-Accarino, Elena et al. DOI: 10.1111/liv.15814
PMID: 38114163 Journal: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER Year: 2023 Reference: Int J Gynecol Cancer. 2023 Dec 18:ijgc-2023-005109. doi: 10.1136/ijgc-2023-005109. Impact factor: Publication type: Paper in international publication Authors: Agusti, Nuria; Angeles, Martina Aida; Barreira-Diaz, Ana; Bilir, Esra; Bizzarri, Nicolo; Bonaldo, Giulio; Buti, Maria; Cucinella, Giuseppe; De Vitis, Luigi Antonio; du Bois, Andreas et al. DOI: 10.1136/ijgc-2023-005109
PMID: 38139013 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2023 Reference: Int J Mol Sci. 2023 Dec 6;24(24):17185. doi: 10.3390/ijms242417185. Impact factor: Publication type: Paper in international publication Authors: Adombi, Caroline Melanie; Buti, Maria; Campos, Carolina; Colomer-Castell, Sergi; Cortese, Maria Francesca; Esteban, Juan Ignacio; Garcia-Cehic, Damir; Gregori, Josep; Ibanez-Lligona, Marta; Quer, Josep et al. DOI: 10.3390/ijms242417185
PMID: 35257411 Journal: CLINICAL TRANSPLANTATION Year: 2022 Reference: Clin Transplant. 2022 Oct;36(10):e14631. doi: 10.1111/ctr.14631. Impact factor: Publication type: Review in international publication Authors: Blumberg, Emily A; Campos-Varela, Isabel; Giorgio, Patricia; Kotton, Camille N; Raptis, Dimitri Aristotle; Saliba, Fauzi; Spiro, Michael; Villamil, Federico; Wey, Emmanuel Q et al. DOI: 10.1111/ctr.14631
PMID: 35255179 Journal: LIVER TRANSPLANTATION Year: 2022 Reference: Liver Transpl. 2022 Jul;28(7):1257-1261. doi: 10.1002/lt.26452. Epub 2022 Apr 28. Impact factor: Publication type: Paper in international publication Authors: Aguilera, Victoria; Baliellas, Carme; Banares, Rafael; Caballero-Marcos, Aranzazu; Campos-Varela, Isabel; Castells, Lluis; Colmenero, Jordi; Diaz, Alba; Gomez-Bravo, Miguel Angel; Gonzalez-Dieguez, Luisa et al. DOI: 10.1002/lt.26452
PMID: 35220659 Journal: LIVER INTERNATIONAL Year: 2022 Reference: Liver Int. 2022 May;42(5):1109-1120. doi: 10.1111/liv.15207. Epub 2022 Mar 7. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Altamirano, Jose; Bataller, Ramon; Bosques-Padilla, Francisco; Brown, Robert S Jr; Caballeria, Juan; Calafat, Margalida; Canete, Nuria; Cirera, Isabel; Garcia-Retortillo, Montserrat et al. DOI: 10.1111/liv.15207
PMID: 35215809 Journal: Viruses-Basel Year: 2022 Reference: Viruses. 2022 Jan 22;14(2). pii: v14020215. doi: 10.3390/v14020215. Impact factor: Publication type: Paper in international publication Authors: Aldama, Unai; Buti, Maria; Casillas, Rosario; Cortese, Maria Francesca; Galan, Anna; Garcia-Garcia, Selene; Gonzalez-Aseguinolaza, Gloria; Gregori, Josep; Najarro, Adrian; Pacin-Ruiz, Beatriz et al. DOI: 10.3390/v14020215
PMID: 33590598 Journal: LIVER INTERNATIONAL Year: 2021 Reference: Liver Int. 2021 Jun;41(6):1227-1242. doi: 10.1111/liv.14825. Epub 2021 Mar 18. Impact factor: Publication type: Paper in international publication Authors: Aghemo, Alessio; Atella, Vincenzo; Augustin, Salvador; Bantel, Heike; Boursier, Jerome; Bugianesi, Elisabetta; Castera, Laurent; Crespo, Javier; Cure, Sandrine; de Ledinghen, Victor et al. DOI: 10.1111/liv.14825
PMID: 33537362 Journal: Open Forum Infectious Diseases Year: 2021 Reference: Open Forum Infect Dis. 2020 Dec 8;8(1):ofaa592. doi: 10.1093/ofid/ofaa592. eCollection 2021 Jan. Impact factor: Publication type: Paper in international publication Authors: Alves, Eduarda; Alves, Eduarda; Alves, Elisenda; Anmella, Gerard; Anmella, Gerard; Aranda, Carmen; Arenas, Andrea; Arenas, Andrea; Asenjo, Maria; Avalos, Maribel et al. DOI: 10.1093/ofid/ofaa592
PMID: 33103277 Journal: CLINICAL TRANSPLANTATION Year: 2021 Reference: Clin Transplant. 2021 Jan;35(1):e14132. doi: 10.1111/ctr.14132. Epub 2020 Dec 16. Impact factor: Publication type: Letter or abstract Authors: Bayes, Beatriu; Bodro, Marta; Cofan, Frederic; Coloma, Emmanuel; Creus, Paula; Cucchiari, David; Diekmann, Fritz; Esforzado, Nuria; Guillen, Elena; Hernandez, Carme et al. DOI: 10.1111/ctr.14132
PMID: 33338545 Journal: JOURNAL OF VIROLOGICAL METHODS Year: 2021 Reference: J Virol Methods. 2021 Mar;289:114039. doi: 10.1016/j.jviromet.2020.114039. Epub 2020 Dec 15. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Lopez, Patricia; Barbosa, Gisela; Barreira-Diaz, Ana; Buti, Maria; Esteban, Rafael; Ferreira, Vicelma; Ferrer-Costa, Roser; Kuchta, Alison; Lopez, Eva; Martinez-Camprecios, Joan et al. DOI: 10.1016/j.jviromet.2020.114039
PMID: 31195161 Journal: Clinical Gastroenterology and Hepatology Year: 2020 Reference: Clin Gastroenterol Hepatol. 2020 Jan;18(1):216-225.e5. doi: 10.1016/j.cgh.2019.05.051. Epub 2019 Jun 11. Impact factor: Publication type: Paper in international publication Authors: Agustin, Salvador; Albillos, Agustin; Aller, Rocio; Ampuero, Javier; Andrade, Raul; Arias Loste, Maria Teresa; Aspichueta, Patricia; Banales, Jesus M; Benlloch, Salvador; Boursier, Jerome et al. DOI: 10.1016/j.cgh.2019.05.051
PMID: 31909352 Journal: Hepatology communications Year: 2020 Reference: Hepatol Commun. 2019 Oct 10;4(1):8-20. doi: 10.1002/hep4.1436. eCollection 2020 Jan. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Chan, Henry L Y; Dusheiko, Geoffrey; Flaherty, John F; Gaggar, Anuj; Ghany, Marc G; Locarnini, Stephen; Lok, Anna S; Marcellin, Patrick; Subramanian, G Mani et al. DOI: 10.1002/hep4.1436
PMID: 31850577 Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS Year: 2020 Reference: Aliment Pharmacol Ther. 2020 Jan;51(1):174-175. doi: 10.1111/apt.15558. Impact factor: Publication type: Editorail in international publication Authors: Buti, Maria; Palom, Adriana; Riveiro-Barciela, Mar et al. DOI: 10.1111/apt.15558
PMID: 31721254 Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS Year: 2020 Reference: Aliment Pharmacol Ther. 2020 Jan;51(1):158-166. doi: 10.1111/apt.15521. Epub 2019 Nov 13. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Esteban, Rafael; Garcia-Samaniego, Javier; Lens, Sabela; Navascues, Carmen A; Palom, Adriana; Riveiro-Barciela, Mar; Rodriguez, Manuel; Rodriguez-Tajes, Sergio et al. DOI: 10.1111/apt.15521
PMID: 28527664 Journal: JOURNAL OF HEPATOLOGY Year: 2017 Reference: J Hepatol. 2017 Oct;67(4):669-679. doi: 10.1016/j.jhep.2017.05.010. Epub 2017 May 18. Impact factor: 12.486 Publication type: Paper in international publication Authors: Ni, Yi, Hommel, Mirja, Palomo, Laura, Segura, Victor, Olague, Cristina, Vales, Africa, Ruiz-Ripa, Alicia, Buti, Maria, Salido, Eduardo, Prieto, Jesus et al. DOI: 10.1016/j.jhep.2017.05.010
PMID: 28392234 Journal: JOURNAL OF HEPATOLOGY Year: 2017 Reference: J Hepatol. 2017 Aug;67(2):246-254. doi: 10.1016/j.jhep.2017.03.027. Epub 2017 Apr 7. Impact factor: 12.486 Publication type: Paper in international publication Authors: Shirvani-Dastgerdi, Elham, Winer, Benjamin Y, Celia-Terrassa, Antoni, Kang, Yibin, Tabernero, David, Yagmur, Eray, Rodriguez-Frias, Francisco, Gregori, Josep, Luedde, Tom, Ploss, Alexander et al. DOI: 10.1016/j.jhep.2017.03.027
PMID: 28189751 Journal: JOURNAL OF HEPATOLOGY Year: 2017 Reference: J Hepatol. 2017 Jun;66(6):1138-1148. doi: 10.1016/j.jhep.2017.01.028. Epub 2017 Feb 9. Impact factor: 12.486 Publication type: Paper in international publication Authors: Llerena, Susana, Pascasio, Juan Manuel, Turnes, Juan, Torras, Xavier, Morillas, Rosa Maria, Llaneras, Jordi, Serra, Miguel A, Diago, Moises, Rodriguez, Conrado Fernandez, Ampuero, Javier et al. DOI: 10.1016/j.jhep.2017.01.028
PMID: 28288829 Journal: CLINICAL MICROBIOLOGY AND INFECTION Year: 2017 Reference: Clin Microbiol Infect. 2017 Nov;23(11):860-867. doi: 10.1016/j.cmi.2017.03.003. Epub 2017 Mar 11. Impact factor: 5.292 Publication type: Paper in international publication Authors: Riveiro-Barciela, Mar, Bes, Marta, Rodriguez-Frias, Francisco, Tabernero, David, Ruiz, Alicia, Casillas, Rosario, Vidal, Judith, Homs, Maria, Nieto, Leonardo, Sauleda, Silvia et al. DOI: 10.1016/j.cmi.2017.03.003
The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.
Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.